Click here to switch to the map view.

The map label for this gene is lysK [H]

Identifier: 88657725

GI number: 88657725

Start: 632092

End: 633627

Strand: Reverse

Name: lysK [H]

Synonym: ECH_0626

Alternate gene names: 88657725

Gene position: 633627-632092 (Counterclockwise)

Preceding gene: 88658360

Following gene: 88657976

Centisome position: 53.87

GC content: 30.4

Gene sequence:

>1536_bases
ATGGTGGGACAGTACAAATTTTGGCCATTTCAAGAAGCAGAAAAAATATTAAAAAGATTTGGGGAGAATACAGAAATTAT
TTTTGAAACTGGTTATGGCCCGTCAGGACTTCCTCATATTGGTACTTTTGGAGAAGTATTACGTACTACAGCAATAATGA
ATGCTCTACGTAAAATCTGTCCTAATATTACAACAAAAGTAATAGTTGTATCAGATGATATGGATGGTCTAAGGAAAGTG
CCAGATAATATTCCAAATAAAGATATGATAGCTGACCATTTAGGTAAACCTTTGACTATGATACCGGATCCTTTTTGTGC
TTGTGAAAGTTACGGGCATCATATGAACATGTTGTTGTGTAGGTTTCTTGATTTATTTAATTTTGAATATGAATTTAAAA
GTGCAACAGAATGTTATAAGAATGGTTTATATGATGAAAAGTTGCTCTTATTGTTGAAAAATTATGATAAAGTGATGGAT
GTTATGCTGCCTACATTAGGTAGTGAAAGACAAAAAACTTATAGCCCATTTTTGCCAATATGTCCTAGAACGTCAAGAGT
ATTACAAGTGCCTATTGTTGATATTGATATTGCATTAGGTACTATTTCTTATCAGGATGAGAATGGGGAAGTTATTCAAG
TTCCAGTTACAGGTGGAAAATGTAAATTACAATGGAAGCCAGATTGGGGTATGAGATGGTCAGCACTTAATGTAAAGTAT
GAAGCATATGGTAAAGATTTGCAGCCATCTGCGGAATTATCTAGTAAAATATGTGAGATTCTAGGTAGTGAACCTCCGGT
TCTATTCTGTTATGAGTTGTTTCTTGATAAAGAAGGTAGGAAAATTTCAAAATCAAAAGGTAATGGTATATCAATAGAAG
ATTGGTTGTCTTATGCTCCTTCTGAAAGTTTAGCATTATATATATTACAGAATCCTAAAAAGGCAAAGAAGTTATATTTT
GATGTTATACCGCGTTCTATGGATGATTATTTATGTCTAGTGGATGATTATCATAAAAATGTTAGTTGTGATAATCCTGT
GTGGCATATTCATAATGGAAATGTGCCATTAATTAATATTTCTGGGTTAAGTTTTTCTTTATTATTGAATTTAGCATCTG
CTTGTAATGCTGAAACTAGTGAAGTATTATGGGGATTCATTGAAAATTACCAAGATAATGATAATCTACAAGATAATAAA
ATATTATCTCAATTAGTAGATTTTTCAGTTAAATATTATCATGATTTTGTAAAACCATATAAGGTTTATAAAACTCCAAA
TCATGATGAAAGAATCATATTAGATGAATTGAAAAATATGCTTAATGATTTCTCAGAAAATATTACATCTGAAGAAATAC
AAAGTAATATATTTTCTTTAATGAAAAAATATTGTTTTAATGATCTGCGATCTTGTTTTCAAAGTTTTTATGAAATTCTA
TTAGGGCAAAGTCATGGCCCTAGGCTTGGATCTTTTGTAAAATTATATGGAGTAAATAATACTATAGACCTAATAAATCA
AGCATTGGAAAGGTGA

Upstream 100 bases:

>100_bases
TTTCGAAATTCATTTTGTGTAATCTTGCTATATATTTGCCACTTTATACATTTTGTGTTATATAGGTGAGTGAGATTATA
AGCTATCAGTTTTATGTATT

Downstream 100 bases:

>100_bases
ACTGTAAGCATCTATTTTGTAGAATAATGTTTTTGTATTTACTAATAGGTATATATTTAAAAATATATAATATGAAATTG
ACCAGTTAATTAAATTATGA

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MVGQYKFWPFQEAEKILKRFGENTEIIFETGYGPSGLPHIGTFGEVLRTTAIMNALRKICPNITTKVIVVSDDMDGLRKV
PDNIPNKDMIADHLGKPLTMIPDPFCACESYGHHMNMLLCRFLDLFNFEYEFKSATECYKNGLYDEKLLLLLKNYDKVMD
VMLPTLGSERQKTYSPFLPICPRTSRVLQVPIVDIDIALGTISYQDENGEVIQVPVTGGKCKLQWKPDWGMRWSALNVKY
EAYGKDLQPSAELSSKICEILGSEPPVLFCYELFLDKEGRKISKSKGNGISIEDWLSYAPSESLALYILQNPKKAKKLYF
DVIPRSMDDYLCLVDDYHKNVSCDNPVWHIHNGNVPLINISGLSFSLLLNLASACNAETSEVLWGFIENYQDNDNLQDNK
ILSQLVDFSVKYYHDFVKPYKVYKTPNHDERIILDELKNMLNDFSENITSEEIQSNIFSLMKKYCFNDLRSCFQSFYEIL
LGQSHGPRLGSFVKLYGVNNTIDLINQALER

Sequences:

>Translated_511_residues
MVGQYKFWPFQEAEKILKRFGENTEIIFETGYGPSGLPHIGTFGEVLRTTAIMNALRKICPNITTKVIVVSDDMDGLRKV
PDNIPNKDMIADHLGKPLTMIPDPFCACESYGHHMNMLLCRFLDLFNFEYEFKSATECYKNGLYDEKLLLLLKNYDKVMD
VMLPTLGSERQKTYSPFLPICPRTSRVLQVPIVDIDIALGTISYQDENGEVIQVPVTGGKCKLQWKPDWGMRWSALNVKY
EAYGKDLQPSAELSSKICEILGSEPPVLFCYELFLDKEGRKISKSKGNGISIEDWLSYAPSESLALYILQNPKKAKKLYF
DVIPRSMDDYLCLVDDYHKNVSCDNPVWHIHNGNVPLINISGLSFSLLLNLASACNAETSEVLWGFIENYQDNDNLQDNK
ILSQLVDFSVKYYHDFVKPYKVYKTPNHDERIILDELKNMLNDFSENITSEEIQSNIFSLMKKYCFNDLRSCFQSFYEIL
LGQSHGPRLGSFVKLYGVNNTIDLINQALER
>Mature_511_residues
MVGQYKFWPFQEAEKILKRFGENTEIIFETGYGPSGLPHIGTFGEVLRTTAIMNALRKICPNITTKVIVVSDDMDGLRKV
PDNIPNKDMIADHLGKPLTMIPDPFCACESYGHHMNMLLCRFLDLFNFEYEFKSATECYKNGLYDEKLLLLLKNYDKVMD
VMLPTLGSERQKTYSPFLPICPRTSRVLQVPIVDIDIALGTISYQDENGEVIQVPVTGGKCKLQWKPDWGMRWSALNVKY
EAYGKDLQPSAELSSKICEILGSEPPVLFCYELFLDKEGRKISKSKGNGISIEDWLSYAPSESLALYILQNPKKAKKLYF
DVIPRSMDDYLCLVDDYHKNVSCDNPVWHIHNGNVPLINISGLSFSLLLNLASACNAETSEVLWGFIENYQDNDNLQDNK
ILSQLVDFSVKYYHDFVKPYKVYKTPNHDERIILDELKNMLNDFSENITSEEIQSNIFSLMKKYCFNDLRSCFQSFYEIL
LGQSHGPRLGSFVKLYGVNNTIDLINQALER

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 58494; Mature: 58494

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGQYKFWPFQEAEKILKRFGENTEIIFETGYGPSGLPHIGTFGEVLRTTAIMNALRKIC
CCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PNITTKVIVVSDDMDGLRKVPDNIPNKDMIADHLGKPLTMIPDPFCACESYGHHMNMLLC
CCCCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHH
RFLDLFNFEYEFKSATECYKNGLYDEKLLLLLKNYDKVMDVMLPTLGSERQKTYSPFLPI
HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCC
CPRTSRVLQVPIVDIDIALGTISYQDENGEVIQVPVTGGKCKLQWKPDWGMRWSALNVKY
CCCCCCEEEEEEEEEEEEEEEEEEECCCCCEEEEEECCCEEEEEECCCCCCEEEEEEEEH
EAYGKDLQPSAELSSKICEILGSEPPVLFCYELFLDKEGRKISKSKGNGISIEDWLSYAP
HHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCEECCCCCCCCCHHHHHHCCC
SESLALYILQNPKKAKKLYFDVIPRSMDDYLCLVDDYHKNVSCDNPVWHIHNGNVPLINI
CCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCEEEEECCCCCEEEE
SGLSFSLLLNLASACNAETSEVLWGFIENYQDNDNLQDNKILSQLVDFSVKYYHDFVKPY
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
KVYKTPNHDERIILDELKNMLNDFSENITSEEIQSNIFSLMKKYCFNDLRSCFQSFYEIL
EEECCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQSHGPRLGSFVKLYGVNNTIDLINQALER
HCCCCCCCCCCEEEEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MVGQYKFWPFQEAEKILKRFGENTEIIFETGYGPSGLPHIGTFGEVLRTTAIMNALRKIC
CCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PNITTKVIVVSDDMDGLRKVPDNIPNKDMIADHLGKPLTMIPDPFCACESYGHHMNMLLC
CCCCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHH
RFLDLFNFEYEFKSATECYKNGLYDEKLLLLLKNYDKVMDVMLPTLGSERQKTYSPFLPI
HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCC
CPRTSRVLQVPIVDIDIALGTISYQDENGEVIQVPVTGGKCKLQWKPDWGMRWSALNVKY
CCCCCCEEEEEEEEEEEEEEEEEEECCCCCEEEEEECCCEEEEEECCCCCCEEEEEEEEH
EAYGKDLQPSAELSSKICEILGSEPPVLFCYELFLDKEGRKISKSKGNGISIEDWLSYAP
HHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCEECCCCCCCCCHHHHHHCCC
SESLALYILQNPKKAKKLYFDVIPRSMDDYLCLVDDYHKNVSCDNPVWHIHNGNVPLINI
CCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCEEEEECCCCCEEEE
SGLSFSLLLNLASACNAETSEVLWGFIENYQDNDNLQDNKILSQLVDFSVKYYHDFVKPY
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
KVYKTPNHDERIILDELKNMLNDFSENITSEEIQSNIFSLMKKYCFNDLRSCFQSFYEIL
EEECCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQSHGPRLGSFVKLYGVNNTIDLINQALER
HCCCCCCCCCCEEEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA