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The map label for this gene is ftsY

Identifier: 88608763

GI number: 88608763

Start: 474851

End: 475780

Strand: Direct

Name: ftsY

Synonym: NSE_0545

Alternate gene names: 88608763

Gene position: 474851-475780 (Clockwise)

Preceding gene: 88608236

Following gene: 88608120

Centisome position: 55.28

GC content: 38.71

Gene sequence:

>930_bases
GTGTTCAAAAGTGTCTTTTCCTCAATTAGAAACTCGATCACAAAGAGTAGAGATTACTTATCAAGTGGAATCGATAATAT
TTTTGCAAAAGAGAAAATAAGTGAATCTACTATTGAACAGTTGGAAGAATTACTTATTTCCGCTGATATTGGCCCTACAG
TGACTGAGAGAATCATTAAAACGGTCAAAAAAATTAAAGTAAAAGATGGCGAGTCACTTGAACAAGTGAAAAGTATTACG
CGTGAAGAAATGAAAAAAGTACTCGATCCCACATCAAAAAAGCTGATTTTCCCACAGACCGGACCTCAAGTCATTGTATT
TTGTGGTGTGAATGGCAATGGTAAGACAACCACTATAGGGAAATTAGCATACAAATTTATTCAAGAGAATAAAACGGTCA
TGATTGCTGCATGTGATCTTTTCAGGGCAGCTGCAATAGAGCAACTGCGTTTCTGGGCGGAAAGAGCATCTGCGACATTT
TTTTCAAGCGAAACAAGCAAAAATGCCTCTGGTACCGCTTATAAAGCCTTAGAAAAAGCTCTAGAAGATAAAGTTGATGT
ACTTATAGTAGATACTTCTGGCAGGTTACACACACAGAATGACCTCATGGAAGAACTCAAAAAGATATGCAGGGTACTTT
CGAAGCTAATGCCCTCAGCACCCAACGAAGTTATACTAGCTCTCGATGCCAGTACTGGGCAAAATGCTCTTAACCAAGTG
CAGGTTTTTAAAGATGCGGTCAATCTCACTGGACTGGTCGTGACAAAATTAGATGGCACGTCCAAAGGAGGAGTGATTGT
AGCTATAGCTGAAAGGTATCCTAATCTTGGGATATACTTTGTTGGGACAGGAGAAAAAATAACCGATCTGGAAGAATTCT
CTCCTTCAGAGTTTGTAGATGCTTTGCTTGAAGTAAAAACTACATCTTAA

Upstream 100 bases:

>100_bases
CTAAGAGGAACTTCTGTTTCCGAATTTTAGAAAAAAATATCCTTCTGCAGAAGTTTCTATGTTAGAGTGAAGTTTCATGG
AGTAAATTAGGCTTATAGTA

Downstream 100 bases:

>100_bases
TAAAATTGTTGCCACAGAATCAGGACCTCAAAAATTCCACAGATTTTTACGACCCGTAATCGGAATAGTAGGGATTCCGC
TTTACTCCACAAAAAAAAAG

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MFKSVFSSIRNSITKSRDYLSSGIDNIFAKEKISESTIEQLEELLISADIGPTVTERIIKTVKKIKVKDGESLEQVKSIT
REEMKKVLDPTSKKLIFPQTGPQVIVFCGVNGNGKTTTIGKLAYKFIQENKTVMIAACDLFRAAAIEQLRFWAERASATF
FSSETSKNASGTAYKALEKALEDKVDVLIVDTSGRLHTQNDLMEELKKICRVLSKLMPSAPNEVILALDASTGQNALNQV
QVFKDAVNLTGLVVTKLDGTSKGGVIVAIAERYPNLGIYFVGTGEKITDLEEFSPSEFVDALLEVKTTS

Sequences:

>Translated_309_residues
MFKSVFSSIRNSITKSRDYLSSGIDNIFAKEKISESTIEQLEELLISADIGPTVTERIIKTVKKIKVKDGESLEQVKSIT
REEMKKVLDPTSKKLIFPQTGPQVIVFCGVNGNGKTTTIGKLAYKFIQENKTVMIAACDLFRAAAIEQLRFWAERASATF
FSSETSKNASGTAYKALEKALEDKVDVLIVDTSGRLHTQNDLMEELKKICRVLSKLMPSAPNEVILALDASTGQNALNQV
QVFKDAVNLTGLVVTKLDGTSKGGVIVAIAERYPNLGIYFVGTGEKITDLEEFSPSEFVDALLEVKTTS
>Mature_309_residues
MFKSVFSSIRNSITKSRDYLSSGIDNIFAKEKISESTIEQLEELLISADIGPTVTERIIKTVKKIKVKDGESLEQVKSIT
REEMKKVLDPTSKKLIFPQTGPQVIVFCGVNGNGKTTTIGKLAYKFIQENKTVMIAACDLFRAAAIEQLRFWAERASATF
FSSETSKNASGTAYKALEKALEDKVDVLIVDTSGRLHTQNDLMEELKKICRVLSKLMPSAPNEVILALDASTGQNALNQV
QVFKDAVNLTGLVVTKLDGTSKGGVIVAIAERYPNLGIYFVGTGEKITDLEEFSPSEFVDALLEVKTTS

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=289, Percent_Identity=33.9100346020761, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI226371618, Length=226, Percent_Identity=38.0530973451327, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI295424842, Length=306, Percent_Identity=28.7581699346405, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI23308697, Length=306, Percent_Identity=28.7581699346405, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI89061728, Length=133, Percent_Identity=36.8421052631579, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI1789874, Length=302, Percent_Identity=43.046357615894, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1788963, Length=297, Percent_Identity=32.996632996633, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=224, Percent_Identity=34.8214285714286, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193206261, Length=296, Percent_Identity=31.4189189189189, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=319, Percent_Identity=30.0940438871473, Blast_Score=148, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6320498, Length=361, Percent_Identity=26.5927977839335, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17647949, Length=280, Percent_Identity=30.7142857142857, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641198, Length=308, Percent_Identity=28.8961038961039, Blast_Score=118, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 33901; Mature: 33901

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSVFSSIRNSITKSRDYLSSGIDNIFAKEKISESTIEQLEELLISADIGPTVTERIIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TVKKIKVKDGESLEQVKSITREEMKKVLDPTSKKLIFPQTGPQVIVFCGVNGNGKTTTIG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCHHHH
KLAYKFIQENKTVMIAACDLFRAAAIEQLRFWAERASATFFSSETSKNASGTAYKALEKA
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHH
LEDKVDVLIVDTSGRLHTQNDLMEELKKICRVLSKLMPSAPNEVILALDASTGQNALNQV
HHCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHH
QVFKDAVNLTGLVVTKLDGTSKGGVIVAIAERYPNLGIYFVGTGEKITDLEEFSPSEFVD
HHHHHHHCCCEEEEEEECCCCCCCEEEEEHHCCCCCCEEEEECCCCHHHHHHCCHHHHHH
ALLEVKTTS
HHHHHHCCC
>Mature Secondary Structure
MFKSVFSSIRNSITKSRDYLSSGIDNIFAKEKISESTIEQLEELLISADIGPTVTERIIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TVKKIKVKDGESLEQVKSITREEMKKVLDPTSKKLIFPQTGPQVIVFCGVNGNGKTTTIG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCHHHH
KLAYKFIQENKTVMIAACDLFRAAAIEQLRFWAERASATFFSSETSKNASGTAYKALEKA
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHH
LEDKVDVLIVDTSGRLHTQNDLMEELKKICRVLSKLMPSAPNEVILALDASTGQNALNQV
HHCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHH
QVFKDAVNLTGLVVTKLDGTSKGGVIVAIAERYPNLGIYFVGTGEKITDLEEFSPSEFVD
HHHHHHHCCCEEEEEEECCCCCCCEEEEEHHCCCCCCEEEEECCCCHHHHHHCCHHHHHH
ALLEVKTTS
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]