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The map label for this gene is trpS

Identifier: 88608758

GI number: 88608758

Start: 180524

End: 181516

Strand: Direct

Name: trpS

Synonym: NSE_0213

Alternate gene names: 88608758

Gene position: 180524-181516 (Clockwise)

Preceding gene: 88608234

Following gene: 88608877

Centisome position: 21.02

GC content: 43.4

Gene sequence:

>993_bases
ATGGTACGGTCTACGGTGGAAGATAAAGCTGTTTTGTCTGGGATCCAGCCAACTGGGTATGTGCAGCTTGGAAATTTGCT
TGGTGCCGTAGACGTATGGGTAGAAATACAGTCTCAGTATAAAAGGAAGTTTTTCTTTATGGCTGATCTACACTCCCTTG
ATGGGGGAACATTAGGTCTGGCTGATGCTTCCATAGAGATGGCTTGCACTTACATAGCGTGTGGCATAGATCCAAATGAT
TGTCGCATATTTGTGCAGTCCCATATCCCTCAGCATGTAGAGCTCTGTTGGTTGCTTGGTTGCATCACTCCTATGGGTCT
GCTCAACAGGATGACTCAGTTTAAGGACAAGTCGAACAGGGAGGGCGTTACTCCGATGCTCTCTTTATATGCTTATCCGG
TTCTAATGGTGGCTGATATACTGCTGTACAATGCAGAAGTTATACCAGTGGGTGATGATCAAACCCAACACGTTGAGTTG
GCAAGAGATGTGGTGCTGCGTTTTAATCAACGTTATGGTGAGTACTTCAGGTTGCCTACGATTCTCAAAAAGAAAGAAGC
CACTAGGATAATGAGCCTCACGAATCCGACAAAAAAGATGAGTAAATCTGATCCCTCGGATTTTTCCAGAATAAATTTAT
CCGATCCAAAGGAGTTGATTGAAAAGAAGATATTATCTGCTAAGACAGACTCTATACTAGGTTTCTCTCCTGAAGGATTG
CAAGACAGACCTGAGGCGTCTAATTTGCTCAACATAGCGGCTTGCCTTAGTGGTAAAAAAGTAGAGCAACTCTGCAACGA
GGTGAGTAATTTTTCTGCTCTAAAATCTATGCTTATCGATCTGCTTCTTGCAAAGCTCCTACCGATACAGGAAAAGAGGA
AGAATCTTGAAAGGGATGCAGTCAAAAAGATGCTTGCTGATTCTGCTGAGGCGATGAGAGAGATAGCTCGTGCAAACCTG
ACGCATATAAAACAGCTTATGCAACTCATTTGA

Upstream 100 bases:

>100_bases
AGGATGGCTATACAATTAAGGGGCGCCTTTTGCGTCCGGCAGTGGTGGTTGTTGTGGAAAATTTAGAGTAAGACTCTTCT
CTTAAAAGGTAAATTGTTTA

Downstream 100 bases:

>100_bases
TCACGTGTAGTTCTAGTTTGTTGCTGTGGGAAGGAATAGATGTTACTATTCCCCCTGAGGTTTTGAGAATGCCTAAGTTA
AAAACTAATTCCAGCGCTAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MVRSTVEDKAVLSGIQPTGYVQLGNLLGAVDVWVEIQSQYKRKFFFMADLHSLDGGTLGLADASIEMACTYIACGIDPND
CRIFVQSHIPQHVELCWLLGCITPMGLLNRMTQFKDKSNREGVTPMLSLYAYPVLMVADILLYNAEVIPVGDDQTQHVEL
ARDVVLRFNQRYGEYFRLPTILKKKEATRIMSLTNPTKKMSKSDPSDFSRINLSDPKELIEKKILSAKTDSILGFSPEGL
QDRPEASNLLNIAACLSGKKVEQLCNEVSNFSALKSMLIDLLLAKLLPIQEKRKNLERDAVKKMLADSAEAMREIARANL
THIKQLMQLI

Sequences:

>Translated_330_residues
MVRSTVEDKAVLSGIQPTGYVQLGNLLGAVDVWVEIQSQYKRKFFFMADLHSLDGGTLGLADASIEMACTYIACGIDPND
CRIFVQSHIPQHVELCWLLGCITPMGLLNRMTQFKDKSNREGVTPMLSLYAYPVLMVADILLYNAEVIPVGDDQTQHVEL
ARDVVLRFNQRYGEYFRLPTILKKKEATRIMSLTNPTKKMSKSDPSDFSRINLSDPKELIEKKILSAKTDSILGFSPEGL
QDRPEASNLLNIAACLSGKKVEQLCNEVSNFSALKSMLIDLLLAKLLPIQEKRKNLERDAVKKMLADSAEAMREIARANL
THIKQLMQLI
>Mature_330_residues
MVRSTVEDKAVLSGIQPTGYVQLGNLLGAVDVWVEIQSQYKRKFFFMADLHSLDGGTLGLADASIEMACTYIACGIDPND
CRIFVQSHIPQHVELCWLLGCITPMGLLNRMTQFKDKSNREGVTPMLSLYAYPVLMVADILLYNAEVIPVGDDQTQHVEL
ARDVVLRFNQRYGEYFRLPTILKKKEATRIMSLTNPTKKMSKSDPSDFSRINLSDPKELIEKKILSAKTDSILGFSPEGL
QDRPEASNLLNIAACLSGKKVEQLCNEVSNFSALKSMLIDLLLAKLLPIQEKRKNLERDAVKKMLADSAEAMREIARANL
THIKQLMQLI

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=34.1389728096677, Blast_Score=204, Evalue=7e-53,
Organism=Homo sapiens, GI41352700, Length=173, Percent_Identity=40.4624277456647, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI1789786, Length=331, Percent_Identity=38.368580060423, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=33.8368580060423, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71982793, Length=342, Percent_Identity=32.7485380116959, Blast_Score=184, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6320474, Length=347, Percent_Identity=37.1757925072046, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24666151, Length=330, Percent_Identity=38.4848484848485, Blast_Score=210, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36979; Mature: 36979

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSTVEDKAVLSGIQPTGYVQLGNLLGAVDVWVEIQSQYKRKFFFMADLHSLDGGTLGL
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ADASIEMACTYIACGIDPNDCRIFVQSHIPQHVELCWLLGCITPMGLLNRMTQFKDKSNR
CCCHHHHHHHHEEECCCCCHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGVTPMLSLYAYPVLMVADILLYNAEVIPVGDDQTQHVELARDVVLRFNQRYGEYFRLPT
CCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHH
ILKKKEATRIMSLTNPTKKMSKSDPSDFSRINLSDPKELIEKKILSAKTDSILGFSPEGL
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
QDRPEASNLLNIAACLSGKKVEQLCNEVSNFSALKSMLIDLLLAKLLPIQEKRKNLERDA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VKKMLADSAEAMREIARANLTHIKQLMQLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MVRSTVEDKAVLSGIQPTGYVQLGNLLGAVDVWVEIQSQYKRKFFFMADLHSLDGGTLGL
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ADASIEMACTYIACGIDPNDCRIFVQSHIPQHVELCWLLGCITPMGLLNRMTQFKDKSNR
CCCHHHHHHHHEEECCCCCHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGVTPMLSLYAYPVLMVADILLYNAEVIPVGDDQTQHVELARDVVLRFNQRYGEYFRLPT
CCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHH
ILKKKEATRIMSLTNPTKKMSKSDPSDFSRINLSDPKELIEKKILSAKTDSILGFSPEGL
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
QDRPEASNLLNIAACLSGKKVEQLCNEVSNFSALKSMLIDLLLAKLLPIQEKRKNLERDA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VKKMLADSAEAMREIARANLTHIKQLMQLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]