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The map label for this gene is yleA [C]

Identifier: 88608641

GI number: 88608641

Start: 697345

End: 698634

Strand: Reverse

Name: yleA [C]

Synonym: NSE_0785

Alternate gene names: 88608641

Gene position: 698634-697345 (Counterclockwise)

Preceding gene: 88608466

Following gene: 88608756

Centisome position: 81.33

GC content: 40.93

Gene sequence:

>1290_bases
GTGGTAATTTTTAACCTACCTGGCTTTTCCAATAAATTCATGGTGAAAGTTATTACTTTTGGGTGTCGTCTGAATTTTTA
TGAGAGTGACCTCATTAAAAACCTCGTAGGTATCCGAGATAGTAGAGAGTGTATCATCATTAATACCTGTGCTGTAACAA
ATGAAGCTGTGCGTCAGGTAAAACAAAAGATAAGAAAGTGTCACAAAGATGAACCTAGTAAGAAGATTATAGTGGTTGGT
TGTGGTCCTCAACTTGACCCTCATGCATATTCACGTATGCCAGGAGTTTTTAAGGTTCTTGGTAATGTTGAAAAACTAAA
AGCCGAAAACTATGCTTCTGAACAAAAGATAGCAGTTGCCGACATAACTGATGCATCCGAGACTGCTTTTTCTAGCACAA
TGATGCCTGTGGTTTCCGCTGTGCGTAAACGGGCTTTTCTTGAGATTCAAAATGGATGCGATCATGATTGCACCTTTTGC
GCAATCACCCTTGCCAGGGGTAAGAATCGCTCTTCAGATGCTATGACAATTGTTTCGGAAGTGCGTAAAATAGTCGCTTT
TGGTATAAATGAGGTCGTGCTTACCGGGGTTGATATTACTGATTATGGGAAAGATCTTTTTGGGAAACCGGCGTTAGTTT
ATTTGCTAAAAAAGATACTAAATGATGTTCCAGAGCTAAAGAGATTGCGTTTATCTTCTGTGGATGTCTCTGAGCTTAGT
GATGATTTCATCGAGTTATTTGCTACCGAGGCTCGTCTAATGCCGCACTTGCACTTAAGCATACAGTCAGGTGATTCCAT
TATCCTGAAGCGGATGAAAAGGAGACACACTCCTGAACAGGTTGTTGAATTTCATTCAAAGATTTTGGCTGTTCGGCCGG
AAACTGGTTTTGGTGCCGACATAATCGTGGGGTTTCCAACAGAGAGTGAAGAAATGTTCCATAATAGTTATGAGTTAATC
AAAAGGCTCGCTATTCCATACCTACACGTTTTTCCTTTTTCGCCTAAAAAAGGAACAAAGGCTGCCTTAATGCCTCAAGT
AGACGGAGTAGTAAAAAAGGGACGTGCGAGGAAGCTTATAAAATTGGGAAAAGAGAATTTGCAAATATTCAATACCATGC
AAGTCGGTAGCATACATAACCTTGTACTTGAGAGAGATAATGTTGGAAGGAGTGAAAATTTTTGTCTCGTGAGACTAGGT
AGCGCCGTAAGTGATGATACTGGTATCATACGCGCCAAGATAACTGGTTGTAGTGACGCGGAGACGCTGTCGGGGCAGAT
TATAGCATGA

Upstream 100 bases:

>100_bases
TGAACAAGCTTAGTTAGTCTTGTCAAAGTTGAGTATTCCTGTAAAAACAGGATTTTGTACATGATCAAATTTTGCAAGGG
TATCTTTTGTCACAATAAAG

Downstream 100 bases:

>100_bases
TGTTTTGTGTTAAGATGCTCACTTCTGGCCTAATAGATGATATAACGCTTTCGCTTCCAGTATAGGAAAGGTAGGGTTCC
AAGAACTTACTACTCGATCT

Product: MiaB family tRNA modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MVIFNLPGFSNKFMVKVITFGCRLNFYESDLIKNLVGIRDSRECIIINTCAVTNEAVRQVKQKIRKCHKDEPSKKIIVVG
CGPQLDPHAYSRMPGVFKVLGNVEKLKAENYASEQKIAVADITDASETAFSSTMMPVVSAVRKRAFLEIQNGCDHDCTFC
AITLARGKNRSSDAMTIVSEVRKIVAFGINEVVLTGVDITDYGKDLFGKPALVYLLKKILNDVPELKRLRLSSVDVSELS
DDFIELFATEARLMPHLHLSIQSGDSIILKRMKRRHTPEQVVEFHSKILAVRPETGFGADIIVGFPTESEEMFHNSYELI
KRLAIPYLHVFPFSPKKGTKAALMPQVDGVVKKGRARKLIKLGKENLQIFNTMQVGSIHNLVLERDNVGRSENFCLVRLG
SAVSDDTGIIRAKITGCSDAETLSGQIIA

Sequences:

>Translated_429_residues
MVIFNLPGFSNKFMVKVITFGCRLNFYESDLIKNLVGIRDSRECIIINTCAVTNEAVRQVKQKIRKCHKDEPSKKIIVVG
CGPQLDPHAYSRMPGVFKVLGNVEKLKAENYASEQKIAVADITDASETAFSSTMMPVVSAVRKRAFLEIQNGCDHDCTFC
AITLARGKNRSSDAMTIVSEVRKIVAFGINEVVLTGVDITDYGKDLFGKPALVYLLKKILNDVPELKRLRLSSVDVSELS
DDFIELFATEARLMPHLHLSIQSGDSIILKRMKRRHTPEQVVEFHSKILAVRPETGFGADIIVGFPTESEEMFHNSYELI
KRLAIPYLHVFPFSPKKGTKAALMPQVDGVVKKGRARKLIKLGKENLQIFNTMQVGSIHNLVLERDNVGRSENFCLVRLG
SAVSDDTGIIRAKITGCSDAETLSGQIIA
>Mature_429_residues
MVIFNLPGFSNKFMVKVITFGCRLNFYESDLIKNLVGIRDSRECIIINTCAVTNEAVRQVKQKIRKCHKDEPSKKIIVVG
CGPQLDPHAYSRMPGVFKVLGNVEKLKAENYASEQKIAVADITDASETAFSSTMMPVVSAVRKRAFLEIQNGCDHDCTFC
AITLARGKNRSSDAMTIVSEVRKIVAFGINEVVLTGVDITDYGKDLFGKPALVYLLKKILNDVPELKRLRLSSVDVSELS
DDFIELFATEARLMPHLHLSIQSGDSIILKRMKRRHTPEQVVEFHSKILAVRPETGFGADIIVGFPTESEEMFHNSYELI
KRLAIPYLHVFPFSPKKGTKAALMPQVDGVVKKGRARKLIKLGKENLQIFNTMQVGSIHNLVLERDNVGRSENFCLVRLG
SAVSDDTGIIRAKITGCSDAETLSGQIIA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=377, Percent_Identity=25.9946949602122, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI28872784, Length=427, Percent_Identity=22.4824355971897, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI28872782, Length=427, Percent_Identity=22.4824355971897, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1786882, Length=402, Percent_Identity=27.1144278606965, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787057, Length=401, Percent_Identity=26.4339152119701, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17553146, Length=434, Percent_Identity=24.6543778801843, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71996771, Length=242, Percent_Identity=26.4462809917355, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356207, Length=403, Percent_Identity=23.0769230769231, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19922432, Length=382, Percent_Identity=26.9633507853403, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47673; Mature: 47673

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIFNLPGFSNKFMVKVITFGCRLNFYESDLIKNLVGIRDSRECIIINTCAVTNEAVRQV
CEEECCCCCCCCEEEEEEEEHHEECCHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHH
KQKIRKCHKDEPSKKIIVVGCGPQLDPHAYSRMPGVFKVLGNVEKLKAENYASEQKIAVA
HHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHCCHHHHHHCCHHHHHHHCCCCCCCEEEE
DITDASETAFSSTMMPVVSAVRKRAFLEIQNGCDHDCTFCAITLARGKNRSSDAMTIVSE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHH
VRKIVAFGINEVVLTGVDITDYGKDLFGKPALVYLLKKILNDVPELKRLRLSSVDVSELS
HHHHHHHCCCCEEEECCCHHHCCHHHCCCHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHH
DDFIELFATEARLMPHLHLSIQSGDSIILKRMKRRHTPEQVVEFHSKILAVRPETGFGAD
HHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCE
IIVGFPTESEEMFHNSYELIKRLAIPYLHVFPFSPKKGTKAALMPQVDGVVKKGRARKLI
EEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEECCCHHHHHHHCCHHHHHH
KLGKENLQIFNTMQVGSIHNLVLERDNVGRSENFCLVRLGSAVSDDTGIIRAKITGCSDA
HHCCCHHEEEEEEECCCHHHHEEECCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCC
ETLSGQIIA
HHCCCCCCC
>Mature Secondary Structure
MVIFNLPGFSNKFMVKVITFGCRLNFYESDLIKNLVGIRDSRECIIINTCAVTNEAVRQV
CEEECCCCCCCCEEEEEEEEHHEECCHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHH
KQKIRKCHKDEPSKKIIVVGCGPQLDPHAYSRMPGVFKVLGNVEKLKAENYASEQKIAVA
HHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHCCHHHHHHCCHHHHHHHCCCCCCCEEEE
DITDASETAFSSTMMPVVSAVRKRAFLEIQNGCDHDCTFCAITLARGKNRSSDAMTIVSE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHH
VRKIVAFGINEVVLTGVDITDYGKDLFGKPALVYLLKKILNDVPELKRLRLSSVDVSELS
HHHHHHHCCCCEEEECCCHHHCCHHHCCCHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHH
DDFIELFATEARLMPHLHLSIQSGDSIILKRMKRRHTPEQVVEFHSKILAVRPETGFGAD
HHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCE
IIVGFPTESEEMFHNSYELIKRLAIPYLHVFPFSPKKGTKAALMPQVDGVVKKGRARKLI
EEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEECCCHHHHHHHCCHHHHHH
KLGKENLQIFNTMQVGSIHNLVLERDNVGRSENFCLVRLGSAVSDDTGIIRAKITGCSDA
HHCCCHHEEEEEEECCCHHHHEEECCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCC
ETLSGQIIA
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]