BacMap

Definition	Neorickettsia sennetsu str. Miyayama chromosome, complete genome.
Accession	NC_007798
Length	859,006

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The map label for this gene is fabG

Identifier: 88608352

GI number: 88608352

Start: 582931

End: 583671

Strand: Reverse

Name: fabG

Synonym: NSE_0665

Alternate gene names: 88608352

Gene position: 583671-582931 (Counterclockwise)

Preceding gene: 88608239

Following gene: 88608882

Centisome position: 67.95

GC content: 44.4

Gene sequence:

>741_bases
ATGGGTTTTAGTCTCCGTGATAAGCGCATACTGGTCACCGGGGCATCTGGAGGTATAGGAGAAGCTTTAATTAGGTATCT
TCATGCCTTGGGAGCCAGACTTGTTATTTCGGGCACTAAAGAGGCGAAATTGCACGCCCTGAACGCAAGTATTGATTGCG
GAGCACATGTTATTGTGCAGGACCTTTCAGATTTGGAGAATGTGCACCTGCTCATAGAAGGCTGTAAGGAAAAACTAGGT
GGTCTGGACGGCTTAGTTTGTAATGCTGGAATCACGGATGATAAATTGTCCTTACGTATGGGGCTAGATTCGTGGCAGAA
GGTTATCAATGTCAATTTAACGTCAAGTTTTATACTCAATAAAAATGCTGCAGTGCTGATGATGCGTCAAAAATATGGGA
GAATAGTGAACATTTCTTCAGTCGTTGCGGTTATGGGTAACTCAGGTCAGGTGAACTATTGTGCCGCAAAAGCTGGGATC
ATAGGTATGTCAAAAAGTTTTGCTCGTGAGTTTGCATCTAAAGGGGTACTGGTGAATTGCATTGCGCCTGGCTTCATCAA
GACTAACATGACGGATAAGCTCACCGAAGAGCAACTTGCACAAGTACTTCCTACCATTCCGATGAAGCGGGTTGGATTAC
CTGAGGAACTATGTGGTATTGTCGCTCTTCTACTCAGTGATATGGCAAGTTATATTACAGGGCAGACTTTCCACGTGAAT
GGCGGAATGTTGATGGTATAG

Upstream 100 bases:

>100_bases
GAAGTTTTGTAAGCAGTTGTATATAATTCTCGATTTGTTCTTGTTTTTCGCGCACGCATGGTGCTAAACTGCCTCCTGGT
TCTATTTTATTAGTCTTGAG

Downstream 100 bases:

>100_bases
TTCTGTGTGCCCCTGAGGACTTTCGCTGTTTAATCCAAGTTGTGCATTAAGTCTGGCTTCCCTCGCCGTCTGTGCTGGCT
TTTTCTAATAGAAAGTTACC

Product: 3-oxoacyl-[acyl-carrier protein] reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MGFSLRDKRILVTGASGGIGEALIRYLHALGARLVISGTKEAKLHALNASIDCGAHVIVQDLSDLENVHLLIEGCKEKLG
GLDGLVCNAGITDDKLSLRMGLDSWQKVINVNLTSSFILNKNAAVLMMRQKYGRIVNISSVVAVMGNSGQVNYCAAKAGI
IGMSKSFAREFASKGVLVNCIAPGFIKTNMTDKLTEEQLAQVLPTIPMKRVGLPEELCGIVALLLSDMASYITGQTFHVN
GGMLMV

Sequences:

>Translated_246_residues
MGFSLRDKRILVTGASGGIGEALIRYLHALGARLVISGTKEAKLHALNASIDCGAHVIVQDLSDLENVHLLIEGCKEKLG
GLDGLVCNAGITDDKLSLRMGLDSWQKVINVNLTSSFILNKNAAVLMMRQKYGRIVNISSVVAVMGNSGQVNYCAAKAGI
IGMSKSFAREFASKGVLVNCIAPGFIKTNMTDKLTEEQLAQVLPTIPMKRVGLPEELCGIVALLLSDMASYITGQTFHVN
GGMLMV
>Mature_245_residues
GFSLRDKRILVTGASGGIGEALIRYLHALGARLVISGTKEAKLHALNASIDCGAHVIVQDLSDLENVHLLIEGCKEKLGG
LDGLVCNAGITDDKLSLRMGLDSWQKVINVNLTSSFILNKNAAVLMMRQKYGRIVNISSVVAVMGNSGQVNYCAAKAGII
GMSKSFAREFASKGVLVNCIAPGFIKTNMTDKLTEEQLAQVLPTIPMKRVGLPEELCGIVALLLSDMASYITGQTFHVNG
GMLMV

Specific function: Proposed to modify Nod factor fatty acyl chain [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=36.0153256704981, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=36.6255144032922, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=31.9838056680162, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=32, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=30.241935483871, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=31.1688311688312, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=29.0196078431373, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4504505, Length=255, Percent_Identity=30.9803921568627, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=29.1497975708502, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI40548397, Length=219, Percent_Identity=30.5936073059361, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI214010158, Length=219, Percent_Identity=30.5936073059361, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI214010156, Length=219, Percent_Identity=30.5936073059361, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI22758144, Length=219, Percent_Identity=30.5936073059361, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=28.2828282828283, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=30.3482587064677, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=28.0701754385965, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI150247226, Length=196, Percent_Identity=31.6326530612245, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=27.4193548387097, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI66933014, Length=219, Percent_Identity=27.8538812785388, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=30.6122448979592, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI19743808, Length=214, Percent_Identity=29.4392523364486, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=30.0518134715026, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI50726952, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4503817, Length=209, Percent_Identity=25.8373205741627, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=28.7234042553192, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=30.8510638297872, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=30.8510638297872, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=30.8510638297872, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI142976729, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=27.0408163265306, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI32455239, Length=173, Percent_Identity=29.4797687861272, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI5031765, Length=173, Percent_Identity=29.4797687861272, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=46.1864406779661, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=31.8725099601594, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=31.5789473684211, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=34.6456692913386, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=30.6451612903226, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788459, Length=192, Percent_Identity=34.375, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=31.1740890688259, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=33.1967213114754, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=31.7991631799163, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787526, Length=246, Percent_Identity=30.0813008130081, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=30.6513409961686, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.5123966942149, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787891, Length=235, Percent_Identity=25.9574468085106, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=39.2712550607287, Blast_Score=170, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=41.3934426229508, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=33.0612244897959, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=31.3008130081301, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=30.4511278195489, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=29.811320754717, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=29.9625468164794, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17568967, Length=253, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=32.5, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=27.7992277992278, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=28.1853281853282, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=27.9693486590038, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=277, Percent_Identity=29.6028880866426, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=29.3893129770992, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=215, Percent_Identity=29.7674418604651, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=27.8195488721804, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=28.9795918367347, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=28.2786885245902, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=212, Percent_Identity=31.1320754716981, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.4354838709677, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=27.0992366412214, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=29.0697674418605, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=26.7924528301887, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=27.906976744186, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=28.7313432835821, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=29.3893129770992, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=246, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.1794871794872, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.984126984127, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=223, Percent_Identity=30.9417040358744, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=251, Percent_Identity=31.0756972111554, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=26.6129032258064, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=258, Percent_Identity=27.1317829457364, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=29.6482412060301, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=35.2226720647773, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=35.2, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=32.9268292682927, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=33.7349397590361, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=32.5301204819277, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=31.1740890688259, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737361, Length=249, Percent_Identity=27.3092369477912, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=31.0204081632653, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859837, Length=245, Percent_Identity=31.4285714285714, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644337, Length=192, Percent_Identity=31.25, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=27.319587628866, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584748, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161076933, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007236, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581726, Length=194, Percent_Identity=26.2886597938144, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 26234; Mature: 26103

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFSLRDKRILVTGASGGIGEALIRYLHALGARLVISGTKEAKLHALNASIDCGAHVIVQ
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCHHHHHH
DLSDLENVHLLIEGCKEKLGGLDGLVCNAGITDDKLSLRMGLDSWQKVINVNLTSSFILN
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHEEECHHHHHHHEECCCCCEEEEC
KNAAVLMMRQKYGRIVNISSVVAVMGNSGQVNYCAAKAGIIGMSKSFAREFASKGVLVNC
CCCEEEEEEHHCCCEEEHHHEEEEECCCCCEEEEEHHCCEECCCHHHHHHHHHCCEEEEE
IAPGFIKTNMTDKLTEEQLAQVLPTIPMKRVGLPEELCGIVALLLSDMASYITGQTFHVN
CCCCEEECCCHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEC
GGMLMV
CCEEEC
>Mature Secondary Structure 
GFSLRDKRILVTGASGGIGEALIRYLHALGARLVISGTKEAKLHALNASIDCGAHVIVQ
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCHHHHHH
DLSDLENVHLLIEGCKEKLGGLDGLVCNAGITDDKLSLRMGLDSWQKVINVNLTSSFILN
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHEEECHHHHHHHEECCCCCEEEEC
KNAAVLMMRQKYGRIVNISSVVAVMGNSGQVNYCAAKAGIIGMSKSFAREFASKGVLVNC
CCCEEEEEEHHCCCEEEHHHEEEEECCCCCEEEEEHHCCEECCCHHHHHHHHHCCEEEEE
IAPGFIKTNMTDKLTEEQLAQVLPTIPMKRVGLPEELCGIVALLLSDMASYITGQTFHVN
CCCCEEECCCHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEC
GGMLMV
CCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9100384 [H]