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The map label for this gene is trxB

Identifier: 88608277

GI number: 88608277

Start: 484685

End: 485629

Strand: Reverse

Name: trxB

Synonym: NSE_0558

Alternate gene names: 88608277

Gene position: 485629-484685 (Counterclockwise)

Preceding gene: 88608779

Following gene: 88608398

Centisome position: 56.53

GC content: 48.57

Gene sequence:

>945_bases
ATGTGTGATGCTCTTGAAAGCGATGTAATAATAATCGGGTCTGGGCCAGCCGGGTGTACGGCTGGGATATACGCGGCACG
TGCATCTCTTAGCGTTGTTATAGTCAGTGGGAATCAGTCAGGTGGGCAACTTACCACAACAACCGAGGTCGAGAATTATC
CGGGTTTTGCTCTACCTGTGCAGGGTCCCTGGCTTATGGAACAAATGCAGCAGCAAGCTGTGAATGTTGGGTGCCGTCTT
GTTAATGATCACATCTTGCAAATTGAAGCCCCATATAGCTCTCCATTTGTCCTTCGAGGAGAGGGTGGAAATAAGTATCG
TGCTAGAAGTATTGTTGTCGCGACAGGTGCACAGGCTAAGTGGTTGGGTCTTGAGAGCGAGAAGAAGTACCAGGGTTATG
GAGTGTCTGGCTGTGCAACGTGTGATGGCTTTTTTTTTCGCGACCAGGACGTAATTGTTATTGGTGGTGGAAATACCGCC
GTAGAAGAGGCACTTTATCTTACCAGGCATGCTAAAAAGGTTTACCTGCTTCACCGTAGGGAACGTCTTAGGGCAGAGAC
TGTCCTTCAGGAACGCCTTTTTGCGAATGCAAAGGTAGAGTTAATTTGGAATTCTGTTCTTGATGAGATCCTTGGCCGCG
ACTCGCCTCCTGAGGTAACAGGTGTGCGTGTCCGCTCATTGATGGACGGTACTTTTAGGGAGATACTTGTTTCTGGAGTG
TTCGTTGCTATCGGTCATGCTCCAAACACAGCGCTGTTCAGCGGTATTCTGGAAATGGATTCTGCTGGGTACATCAAGAC
ATCCAGTTCAGATACTTCTACTAGCGTGTCTGGTATTTTTGCGTGTGGCGATGTTCAGGATCCTGTCTACAGACAAGCTG
TTACCGCAGCTGGAACCGGTTGTATGGCTGCCCTTGATGCCATAAGGTTTCTTGACTGCATATAG

Upstream 100 bases:

>100_bases
TTGTCCGGCAGGTTGGAGCAAGGGCAAAGAAGCGATAAAGGCGACGCATGAGAGTATTTCCGATTATCTAGCTTCCAATA
GGGATGAGCTTTGACTAAAG

Downstream 100 bases:

>100_bases
TTTATACTCTTTGCGTGTTAGCTTGTAAGATGTGTGTGCAAGCCACGGAGCACTGTCTATTTTTTGTCTGGGGGATGTTT
GTTTTTTGTGTGGCGGTGTA

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MCDALESDVIIIGSGPAGCTAGIYAARASLSVVIVSGNQSGGQLTTTTEVENYPGFALPVQGPWLMEQMQQQAVNVGCRL
VNDHILQIEAPYSSPFVLRGEGGNKYRARSIVVATGAQAKWLGLESEKKYQGYGVSGCATCDGFFFRDQDVIVIGGGNTA
VEEALYLTRHAKKVYLLHRRERLRAETVLQERLFANAKVELIWNSVLDEILGRDSPPEVTGVRVRSLMDGTFREILVSGV
FVAIGHAPNTALFSGILEMDSAGYIKTSSSDTSTSVSGIFACGDVQDPVYRQAVTAAGTGCMAALDAIRFLDCI

Sequences:

>Translated_314_residues
MCDALESDVIIIGSGPAGCTAGIYAARASLSVVIVSGNQSGGQLTTTTEVENYPGFALPVQGPWLMEQMQQQAVNVGCRL
VNDHILQIEAPYSSPFVLRGEGGNKYRARSIVVATGAQAKWLGLESEKKYQGYGVSGCATCDGFFFRDQDVIVIGGGNTA
VEEALYLTRHAKKVYLLHRRERLRAETVLQERLFANAKVELIWNSVLDEILGRDSPPEVTGVRVRSLMDGTFREILVSGV
FVAIGHAPNTALFSGILEMDSAGYIKTSSSDTSTSVSGIFACGDVQDPVYRQAVTAAGTGCMAALDAIRFLDCI
>Mature_314_residues
MCDALESDVIIIGSGPAGCTAGIYAARASLSVVIVSGNQSGGQLTTTTEVENYPGFALPVQGPWLMEQMQQQAVNVGCRL
VNDHILQIEAPYSSPFVLRGEGGNKYRARSIVVATGAQAKWLGLESEKKYQGYGVSGCATCDGFFFRDQDVIVIGGGNTA
VEEALYLTRHAKKVYLLHRRERLRAETVLQERLFANAKVELIWNSVLDEILGRDSPPEVTGVRVRSLMDGTFREILVSGV
FVAIGHAPNTALFSGILEMDSAGYIKTSSSDTSTSVSGIFACGDVQDPVYRQAVTAAGTGCMAALDAIRFLDCI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=51.5625, Blast_Score=310, Evalue=6e-86,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=33.4415584415584, Blast_Score=138, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=41.875, Blast_Score=251, Evalue=8e-68,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=41.0094637223975, Blast_Score=238, Evalue=9e-64,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33643; Mature: 33643

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDALESDVIIIGSGPAGCTAGIYAARASLSVVIVSGNQSGGQLTTTTEVENYPGFALPV
CCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCCCEEEEC
QGPWLMEQMQQQAVNVGCRLVNDHILQIEAPYSSPFVLRGEGGNKYRARSIVVATGAQAK
CCHHHHHHHHHHHHHHCEEEECCEEEEEECCCCCCEEEECCCCCCEEEEEEEEEECCCEE
WLGLESEKKYQGYGVSGCATCDGFFFRDQDVIVIGGGNTAVEEALYLTRHAKKVYLLHRR
EECCCCCCCCCCCCCCCEEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEHHHH
ERLRAETVLQERLFANAKVELIWNSVLDEILGRDSPPEVTGVRVRSLMDGTFREILVSGV
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCE
FVAIGHAPNTALFSGILEMDSAGYIKTSSSDTSTSVSGIFACGDVQDPVYRQAVTAAGTG
EEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCH
CMAALDAIRFLDCI
HHHHHHHHHHHHCC
>Mature Secondary Structure
MCDALESDVIIIGSGPAGCTAGIYAARASLSVVIVSGNQSGGQLTTTTEVENYPGFALPV
CCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCCCEEEEC
QGPWLMEQMQQQAVNVGCRLVNDHILQIEAPYSSPFVLRGEGGNKYRARSIVVATGAQAK
CCHHHHHHHHHHHHHHCEEEECCEEEEEECCCCCCEEEECCCCCCEEEEEEEEEECCCEE
WLGLESEKKYQGYGVSGCATCDGFFFRDQDVIVIGGGNTAVEEALYLTRHAKKVYLLHRR
EECCCCCCCCCCCCCCCEEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEHHHH
ERLRAETVLQERLFANAKVELIWNSVLDEILGRDSPPEVTGVRVRSLMDGTFREILVSGV
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCE
FVAIGHAPNTALFSGILEMDSAGYIKTSSSDTSTSVSGIFACGDVQDPVYRQAVTAAGTG
EEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCH
CMAALDAIRFLDCI
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]