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The map label for this gene is infC

Identifier: 88608274

GI number: 88608274

Start: 237738

End: 238307

Strand: Reverse

Name: infC

Synonym: NSE_0293

Alternate gene names: 88608274

Gene position: 238307-237738 (Counterclockwise)

Preceding gene: 88608148

Following gene: 88608879

Centisome position: 27.74

GC content: 39.12

Gene sequence:

>570_bases
TTGAAGAATAAAGAAAAAAGTTTTACTAACCGTACTCCAAGTAGGTCTAATACAGACAAAAGAATTGTCTGGAGTTACGC
AAACGCGAACAACGAAGTAAGAGTGATAGACGTGAACGATAAGTTCATGGGAGTGATGAAGATCGCGGAAGCGTTGCAGC
TGGCAAAAAGCAGGAATTTAGACTTGGTGGAGGTATCCTCAGCTGTATTTCCACCGATATGTAAAATATTGGACTACGGA
AAATATAAGTACGAGGCAAAGAAGGAGTCCAACCTAAAACGGAGAAAACAAAAATCCTCTACGATAAAAGAGGTTCAGTT
ACGCCAATCCATAGGAGCAGGCGATCTGAGTACAAAACTCAAAAAAATTAGGGAGTTTTTGCAGGAGGAAGACAAAGTAA
AAGTTGTAGTGAGACTCCGTGGTAGGGAAATGACTAACAAAAACCTTGCTATTAACTTACTGAACAAGGTCGTAGAGGAA
GTCGGATCTGAGGTTGGTAAATTGGAAAAAGAGATTGTACAGAATAACAATAATTTTTTTATCATCCTTGCTCCCAATGC
AAAGTCGTAA

Upstream 100 bases:

>100_bases
AGTGAAGACAGTTGATACAGCCCTTGGGGATATATTGAGGGAGTTCAATGTTAGATAAATAAGTAGTACTAATATAAGAA
GAATTTGAGGTTCAATAAAT

Downstream 100 bases:

>100_bases
GGAAAGAAAGCAGGACGTATTTACAAAATGTGCGACATGCTTTGGTATCGGTTACCTTTCTCCGTTACCTGGTACACTGG
GTAGCATACTTGCATTTGTT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKNKEKSFTNRTPSRSNTDKRIVWSYANANNEVRVIDVNDKFMGVMKIAEALQLAKSRNLDLVEVSSAVFPPICKILDYG
KYKYEAKKESNLKRRKQKSSTIKEVQLRQSIGAGDLSTKLKKIREFLQEEDKVKVVVRLRGREMTNKNLAINLLNKVVEE
VGSEVGKLEKEIVQNNNNFFIILAPNAKS

Sequences:

>Translated_189_residues
MKNKEKSFTNRTPSRSNTDKRIVWSYANANNEVRVIDVNDKFMGVMKIAEALQLAKSRNLDLVEVSSAVFPPICKILDYG
KYKYEAKKESNLKRRKQKSSTIKEVQLRQSIGAGDLSTKLKKIREFLQEEDKVKVVVRLRGREMTNKNLAINLLNKVVEE
VGSEVGKLEKEIVQNNNNFFIILAPNAKS
>Mature_189_residues
MKNKEKSFTNRTPSRSNTDKRIVWSYANANNEVRVIDVNDKFMGVMKIAEALQLAKSRNLDLVEVSSAVFPPICKILDYG
KYKYEAKKESNLKRRKQKSSTIKEVQLRQSIGAGDLSTKLKKIREFLQEEDKVKVVVRLRGREMTNKNLAINLLNKVVEE
VGSEVGKLEKEIVQNNNNFFIILAPNAKS

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=190, Percent_Identity=33.6842105263158, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21617; Mature: 21617

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKEKSFTNRTPSRSNTDKRIVWSYANANNEVRVIDVNDKFMGVMKIAEALQLAKSRNL
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
DLVEVSSAVFPPICKILDYGKYKYEAKKESNLKRRKQKSSTIKEVQLRQSIGAGDLSTKL
CEEEHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KKIREFLQEEDKVKVVVRLRGREMTNKNLAINLLNKVVEEVGSEVGKLEKEIVQNNNNFF
HHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IILAPNAKS
EEECCCCCC
>Mature Secondary Structure
MKNKEKSFTNRTPSRSNTDKRIVWSYANANNEVRVIDVNDKFMGVMKIAEALQLAKSRNL
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
DLVEVSSAVFPPICKILDYGKYKYEAKKESNLKRRKQKSSTIKEVQLRQSIGAGDLSTKL
CEEEHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KKIREFLQEEDKVKVVVRLRGREMTNKNLAINLLNKVVEEVGSEVGKLEKEIVQNNNNFF
HHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IILAPNAKS
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA