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The map label for this gene is ctaC [H]

Identifier: 88608267

GI number: 88608267

Start: 542756

End: 543523

Strand: Direct

Name: ctaC [H]

Synonym: NSE_0621

Alternate gene names: 88608267

Gene position: 542756-543523 (Clockwise)

Preceding gene: 88608122

Following gene: 88608253

Centisome position: 63.18

GC content: 43.23

Gene sequence:

>768_bases
ATGCGGAAGCTTGTTTTAATACTCATCTTTCTGTTGCCGGTCTTCGGTTTTAGCGAACAACTTGGACAACCCTATGAATG
GCAGCTTGGATTTCAGCGATCAGCTAGTCCTGTGATGGACTATATCAATGACTTCCACAATCTAATGCTGATAATCATGA
TTTGCATTGCCGCTGGGGTTAATGCTCTTCTCCTATATACTGTTATCCGGTTTAACAAGAAGAGGAATCCATCTCCTTCT
GGGACATCGCACAATACTTTGCTGGAAATTATTTGGACAGTGATACCAGTGCTTATCGTGGTAGGCATCTCTTTCCCTTC
ATTAAAGGTGCTAAAATACGAGGAGCATGTTCCAGATGCAGACATGACAGTCAAAGTTATCGGGCATCAATGGTATTGGA
CGTACAACTACCCGGATCATGGTGAAATTACCTTCGACAGCAATTTAAAGCACGACTTGGATGAGGGCGAACCTCGATTG
CTGGCTGTAGACAATAATCTCGTCTTACCTGTTGATACGACAGTAAGAATTCAAATTACTTCCGATGATGTAATACATAG
CTGGGCGGTGCCGTCGCTTGGAATAAAAAAGGATGCGATCCCAGGTAGACTAAATGAAACCTGGGTTCGTATTGACAAGG
AAGGCACTTACTACGGACAGTGCTCTGAGCTTTGTGGTATACTGCACGGGTTTATGCCTATAGCTGTGACTGCCGTAAGT
AAAGAAGCATTTAAAGAATGGGTTACTCAAGCGAAAGACAGTTTTTAG

Upstream 100 bases:

>100_bases
ACTTATCTGCGAGCATTGCGCTTGCTAGTATGTTTGTGGTATTAAAGATCTTCTATTCGTGTTGTATAATTGATCAACTC
TTTAGGATCGACGTCGTTTT

Downstream 100 bases:

>100_bases
TTTTGGAGATTAGTTAAGGTTAATTATTATGAATAAACATTCAGAGGTCCCTAGCGGCATAAGGCGTTGGCTTTTTTCAA
CAAATCATAAAGACATAGGC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MRKLVLILIFLLPVFGFSEQLGQPYEWQLGFQRSASPVMDYINDFHNLMLIIMICIAAGVNALLLYTVIRFNKKRNPSPS
GTSHNTLLEIIWTVIPVLIVVGISFPSLKVLKYEEHVPDADMTVKVIGHQWYWTYNYPDHGEITFDSNLKHDLDEGEPRL
LAVDNNLVLPVDTTVRIQITSDDVIHSWAVPSLGIKKDAIPGRLNETWVRIDKEGTYYGQCSELCGILHGFMPIAVTAVS
KEAFKEWVTQAKDSF

Sequences:

>Translated_255_residues
MRKLVLILIFLLPVFGFSEQLGQPYEWQLGFQRSASPVMDYINDFHNLMLIIMICIAAGVNALLLYTVIRFNKKRNPSPS
GTSHNTLLEIIWTVIPVLIVVGISFPSLKVLKYEEHVPDADMTVKVIGHQWYWTYNYPDHGEITFDSNLKHDLDEGEPRL
LAVDNNLVLPVDTTVRIQITSDDVIHSWAVPSLGIKKDAIPGRLNETWVRIDKEGTYYGQCSELCGILHGFMPIAVTAVS
KEAFKEWVTQAKDSF
>Mature_255_residues
MRKLVLILIFLLPVFGFSEQLGQPYEWQLGFQRSASPVMDYINDFHNLMLIIMICIAAGVNALLLYTVIRFNKKRNPSPS
GTSHNTLLEIIWTVIPVLIVVGISFPSLKVLKYEEHVPDADMTVKVIGHQWYWTYNYPDHGEITFDSNLKHDLDEGEPRL
LAVDNNLVLPVDTTVRIQITSDDVIHSWAVPSLGIKKDAIPGRLNETWVRIDKEGTYYGQCSELCGILHGFMPIAVTAVS
KEAFKEWVTQAKDSF

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=222, Percent_Identity=43.6936936936937, Blast_Score=192, Evalue=2e-49,
Organism=Escherichia coli, GI1786635, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=235, Percent_Identity=41.7021276595745, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 28932; Mature: 28932

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLVLILIFLLPVFGFSEQLGQPYEWQLGFQRSASPVMDYINDFHNLMLIIMICIAAGV
CHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
NALLLYTVIRFNKKRNPSPSGTSHNTLLEIIWTVIPVLIVVGISFPSLKVLKYEEHVPDA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
DMTVKVIGHQWYWTYNYPDHGEITFDSNLKHDLDEGEPRLLAVDNNLVLPVDTTVRIQIT
CCEEEEEECEEEEEECCCCCCCEEECCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEEC
SDDVIHSWAVPSLGIKKDAIPGRLNETWVRIDKEGTYYGQCSELCGILHGFMPIAVTAVS
CCCHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KEAFKEWVTQAKDSF
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKLVLILIFLLPVFGFSEQLGQPYEWQLGFQRSASPVMDYINDFHNLMLIIMICIAAGV
CHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
NALLLYTVIRFNKKRNPSPSGTSHNTLLEIIWTVIPVLIVVGISFPSLKVLKYEEHVPDA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
DMTVKVIGHQWYWTYNYPDHGEITFDSNLKHDLDEGEPRLLAVDNNLVLPVDTTVRIQIT
CCEEEEEECEEEEEECCCCCCCEEECCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEEC
SDDVIHSWAVPSLGIKKDAIPGRLNETWVRIDKEGTYYGQCSELCGILHGFMPIAVTAVS
CCCHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KEAFKEWVTQAKDSF
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA