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The map label for this gene is pdxH [H]

Identifier: 88608240

GI number: 88608240

Start: 305092

End: 305652

Strand: Reverse

Name: pdxH [H]

Synonym: NSE_0371

Alternate gene names: 88608240

Gene position: 305652-305092 (Counterclockwise)

Preceding gene: 88608299

Following gene: 88608711

Centisome position: 35.58

GC content: 42.42

Gene sequence:

>561_bases
ATGGATACGGATCCAATTGCACAGTTTTTGCTATGGCAAAAGGAGGCTGATGCTTACGACAGAACTGCTGCTGTGCTTGC
AACATGTACGAGGGATAATATTCCCTATGCGAGGACAATTTTAGTGAAGGATGTTACTGCAGATGGATTTACATTCTACA
CCAATATGAATAGTACCAAAGGTAAAAACTTGTTCGATAATCCAAGAGCAGCAATCGTATTTTACTGGAACGAAAGACAG
GTTATCGGACGTGGGAATGTTTTCCTCGTAGATGAAAAGGAAGCAGACACAAGCTTTGCCTTTCGCCCACGAAGTAGCAG
AGCTGTCACCACAATTTCCAAGCAATCTCAAGAATTAACAGACGAAACACTTTTCCTTAATGCGGTGAAAAAGCTAGAAA
ATTCCAGCGACCCAATAGGACGACCAAAACACTGGGTGGGATTCCGGTTGAAGCCATACGCTATGGAGTTTTTCCTTGCT
GGCAAACACAGATTGAACAAAAGATACCTATATCTTCTCCAATCAGACGGAAAGTGGAAAATCTCTAGGCTGTATCCATA
G

Upstream 100 bases:

>100_bases
CTTTGCAACTTCTTTTTTTTATGAAAATTTCCTTGCATAAAAAAGTAATGTATGATTCCTGCATCATGATTAATGTATAG
TGAACCTGGTAGGCTTTTGA

Downstream 100 bases:

>100_bases
GTATTTCAGATAAAGAAGACATATACTGAAAAATCAACGCTGAGCAGGCAATGATGCCCACAGCCGAACCACACTGCGAG
AAACGAGAGTACAGATCAAG

Product: putative pyridoxamine 5-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDTDPIAQFLLWQKEADAYDRTAAVLATCTRDNIPYARTILVKDVTADGFTFYTNMNSTKGKNLFDNPRAAIVFYWNERQ
VIGRGNVFLVDEKEADTSFAFRPRSSRAVTTISKQSQELTDETLFLNAVKKLENSSDPIGRPKHWVGFRLKPYAMEFFLA
GKHRLNKRYLYLLQSDGKWKISRLYP

Sequences:

>Translated_186_residues
MDTDPIAQFLLWQKEADAYDRTAAVLATCTRDNIPYARTILVKDVTADGFTFYTNMNSTKGKNLFDNPRAAIVFYWNERQ
VIGRGNVFLVDEKEADTSFAFRPRSSRAVTTISKQSQELTDETLFLNAVKKLENSSDPIGRPKHWVGFRLKPYAMEFFLA
GKHRLNKRYLYLLQSDGKWKISRLYP
>Mature_186_residues
MDTDPIAQFLLWQKEADAYDRTAAVLATCTRDNIPYARTILVKDVTADGFTFYTNMNSTKGKNLFDNPRAAIVFYWNERQ
VIGRGNVFLVDEKEADTSFAFRPRSSRAVTTISKQSQELTDETLFLNAVKKLENSSDPIGRPKHWVGFRLKPYAMEFFLA
GKHRLNKRYLYLLQSDGKWKISRLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=176, Percent_Identity=39.7727272727273, Blast_Score=121, Evalue=3e-28,
Organism=Escherichia coli, GI1787926, Length=195, Percent_Identity=35.8974358974359, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17553712, Length=198, Percent_Identity=31.8181818181818, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6319509, Length=197, Percent_Identity=32.48730964467, Blast_Score=81, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24644901, Length=159, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45551845, Length=159, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 21503; Mature: 21503

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTDPIAQFLLWQKEADAYDRTAAVLATCTRDNIPYARTILVKDVTADGFTFYTNMNSTK
CCCHHHHHHHHHCCCCCCHHHHEEEEEEECCCCCCEEEEEEEEEECCCCEEEEEECCCCC
GKNLFDNPRAAIVFYWNERQVIGRGNVFLVDEKEADTSFAFRPRSSRAVTTISKQSQELT
CCCCCCCCCEEEEEEECCEEEEECCCEEEEECCCCCCEEEECCCCCCEEEEEHHHHHHHH
DETLFLNAVKKLENSSDPIGRPKHWVGFRLKPYAMEFFLAGKHRLNKRYLYLLQSDGKWK
HHHHHHHHHHHHCCCCCCCCCCCCEECEEECHHEEEEEECCCCCCCCEEEEEEECCCCEE
ISRLYP
EEECCC
>Mature Secondary Structure
MDTDPIAQFLLWQKEADAYDRTAAVLATCTRDNIPYARTILVKDVTADGFTFYTNMNSTK
CCCHHHHHHHHHCCCCCCHHHHEEEEEEECCCCCCEEEEEEEEEECCCCEEEEEECCCCC
GKNLFDNPRAAIVFYWNERQVIGRGNVFLVDEKEADTSFAFRPRSSRAVTTISKQSQELT
CCCCCCCCCEEEEEEECCEEEEECCCEEEEECCCCCCEEEECCCCCCEEEEEHHHHHHHH
DETLFLNAVKKLENSSDPIGRPKHWVGFRLKPYAMEFFLAGKHRLNKRYLYLLQSDGKWK
HHHHHHHHHHHHCCCCCCCCCCCCEECEEECHHEEEEEECCCCCCCCEEEEEEECCCCEE
ISRLYP
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA