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The map label for this gene is coq7 [H]

Identifier: 88608210

GI number: 88608210

Start: 278349

End: 278876

Strand: Reverse

Name: coq7 [H]

Synonym: NSE_0339

Alternate gene names: 88608210

Gene position: 278876-278349 (Counterclockwise)

Preceding gene: 88608168

Following gene: 88608577

Centisome position: 32.46

GC content: 39.39

Gene sequence:

>528_bases
ATGAAAGCCGGTCCGCTAATTGAGAGAATATTAAGAGTAAACCATGCAGGCGAATCAGCTGCTGTGTATATTTACAGAGG
CCAATTGCGTGGCCTTAAGAATAATCCAGAGAAGAGAGAATTGATTTACGAGATGATGAAAACCGAACAAAAGCATCTAC
AGTTTTTTCATTCTCAAATTATTCAATTGAGGGCTAGGCCAACTATTCTGTTGGGAGTTTGGAAAGGCATTGCTTTTGGA
GTGGGATACCTAAGTGCTAAGGCGGGCATCCAAGTTGCAATGTCTTGTACCGCTGCAATTGAAGATACAATAGATAGACA
CTACCAAAAACAAATAAAGTTTCTCACAAAGGTTAAACCAAACGAGCCTCAACTCTTGGAAAAAATCGTGCAATTTCACC
AAGAAGAAGTTGAACATAAAGACATAGGGTTGGCAAATGAGGCAAAAAAAGCACCATTTCATTCCATCATCACAGGAGTT
GTAAGTCTAGGTTGCAGAGTTGGGATTTTCATCGCAGAAAAAATTTAG

Upstream 100 bases:

>100_bases
TGTGATAATCCACAAAAATTACTTGGAATACGTTTGACTTATTTAAATCTGTTGTATTCTCTAGGGAGTGCACTTTTGGT
AATTTTTGCGTGTATTAAAA

Downstream 100 bases:

>100_bases
GTATATTCTTTTGCAGTTGTACACCCCTCTTCGAAGTGGCGCATTCTATTGCAGCGAGATTTGTGAGGGAACTAAAATGT
TTAGCATCGCAGATTAGCGG

Product: Coq7 family protein

Products: NA

Alternate protein names: 5-demethoxyubiquinone hydroxylase; DMQ hydroxylase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKAGPLIERILRVNHAGESAAVYIYRGQLRGLKNNPEKRELIYEMMKTEQKHLQFFHSQIIQLRARPTILLGVWKGIAFG
VGYLSAKAGIQVAMSCTAAIEDTIDRHYQKQIKFLTKVKPNEPQLLEKIVQFHQEEVEHKDIGLANEAKKAPFHSIITGV
VSLGCRVGIFIAEKI

Sequences:

>Translated_175_residues
MKAGPLIERILRVNHAGESAAVYIYRGQLRGLKNNPEKRELIYEMMKTEQKHLQFFHSQIIQLRARPTILLGVWKGIAFG
VGYLSAKAGIQVAMSCTAAIEDTIDRHYQKQIKFLTKVKPNEPQLLEKIVQFHQEEVEHKDIGLANEAKKAPFHSIITGV
VSLGCRVGIFIAEKI
>Mature_175_residues
MKAGPLIERILRVNHAGESAAVYIYRGQLRGLKNNPEKRELIYEMMKTEQKHLQFFHSQIIQLRARPTILLGVWKGIAFG
VGYLSAKAGIQVAMSCTAAIEDTIDRHYQKQIKFLTKVKPNEPQLLEKIVQFHQEEVEHKDIGLANEAKKAPFHSIITGV
VSLGCRVGIFIAEKI

Specific function: Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol [H]

COG id: COG2941

COG function: function code H; Ubiquinone biosynthesis protein COQ7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COQ7 family [H]

Homologues:

Organism=Homo sapiens, GI25453484, Length=170, Percent_Identity=37.6470588235294, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI300244542, Length=170, Percent_Identity=37.6470588235294, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17552756, Length=171, Percent_Identity=35.672514619883, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324699, Length=183, Percent_Identity=31.6939890710383, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24640215, Length=170, Percent_Identity=38.2352941176471, Blast_Score=121, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR011566 [H]

Pfam domain/function: PF03232 COQ7 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 19789; Mature: 19789

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAGPLIERILRVNHAGESAAVYIYRGQLRGLKNNPEKRELIYEMMKTEQKHLQFFHSQI
CCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IQLRARPTILLGVWKGIAFGVGYLSAKAGIQVAMSCTAAIEDTIDRHYQKQIKFLTKVKP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEPQLLEKIVQFHQEEVEHKDIGLANEAKKAPFHSIITGVVSLGCRVGIFIAEKI
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MKAGPLIERILRVNHAGESAAVYIYRGQLRGLKNNPEKRELIYEMMKTEQKHLQFFHSQI
CCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IQLRARPTILLGVWKGIAFGVGYLSAKAGIQVAMSCTAAIEDTIDRHYQKQIKFLTKVKP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEPQLLEKIVQFHQEEVEHKDIGLANEAKKAPFHSIITGVVSLGCRVGIFIAEKI
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA