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The map label for this gene is iscU

Identifier: 88608191

GI number: 88608191

Start: 244519

End: 244947

Strand: Reverse

Name: iscU

Synonym: NSE_0302

Alternate gene names: 88608191

Gene position: 244947-244519 (Counterclockwise)

Preceding gene: 88608058

Following gene: 88608116

Centisome position: 28.52

GC content: 41.49

Gene sequence:

>429_bases
ATGGCTTATAGTGATTCCGTATTAAATCATTACAACAATCCAAGAAATGTTGGTACAATTGACAAGAACAAAAAAAATGT
AGGAACCGGCTTAGTGGGTGCTCCAGCCTGCGGGGATGTAATGAGATTACAGATCGAAGTTGATAATAACGGTTGCATTG
TAGACGCAAAGTTCAAAACCTTTGGTTGTGGTTCAGCGATAGCATCAAGCTCCTTAGCAACAGAGTACCTGATCGGGAAA
AGCATCGAGGAAGCCGAAAAAATCAAGAATACTGAGATCGCATCTACTTTGTGTCTCCCACCGATAAAAATGCACTGCTC
AATGCTGGCAGAGGATGCAATCAAAGCTGCTATCAAAGATTTTAGAGAGAAACAGGTGACTTCTAGCACTGAGGAGGCAG
GTAACGAAAATACAGAGAACAAAAGCTAA

Upstream 100 bases:

>100_bases
CAAGAAGGGATAGATCTTAACTCAATAAAATGGGATACGAGCTAGGCAAACGGTTTACAAAATAGGTAATATTGATATTT
AGTTTAGGAGGAGGACGTTT

Downstream 100 bases:

>100_bases
AGCAAGGCTCCTCATATCTAGATTCAGATGAACTTAAATGGACCACCCATCGCAGTGAGCGCTTTGGCATTTCAGAAGTT
TGTTGAACTGATCGATGAAA

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAYSDSVLNHYNNPRNVGTIDKNKKNVGTGLVGAPACGDVMRLQIEVDNNGCIVDAKFKTFGCGSAIASSSLATEYLIGK
SIEEAEKIKNTEIASTLCLPPIKMHCSMLAEDAIKAAIKDFREKQVTSSTEEAGNENTENKS

Sequences:

>Translated_142_residues
MAYSDSVLNHYNNPRNVGTIDKNKKNVGTGLVGAPACGDVMRLQIEVDNNGCIVDAKFKTFGCGSAIASSSLATEYLIGK
SIEEAEKIKNTEIASTLCLPPIKMHCSMLAEDAIKAAIKDFREKQVTSSTEEAGNENTENKS
>Mature_141_residues
AYSDSVLNHYNNPRNVGTIDKNKKNVGTGLVGAPACGDVMRLQIEVDNNGCIVDAKFKTFGCGSAIASSSLATEYLIGKS
IEEAEKIKNTEIASTLCLPPIKMHCSMLAEDAIKAAIKDFREKQVTSSTEEAGNENTENKS

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=123, Percent_Identity=73.1707317073171, Blast_Score=200, Evalue=3e-52,
Organism=Homo sapiens, GI24307953, Length=122, Percent_Identity=73.7704918032787, Blast_Score=198, Evalue=2e-51,
Organism=Escherichia coli, GI1788878, Length=125, Percent_Identity=67.2, Blast_Score=188, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17543474, Length=123, Percent_Identity=70.7317073170732, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6325122, Length=128, Percent_Identity=67.1875, Blast_Score=181, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6324800, Length=124, Percent_Identity=67.741935483871, Blast_Score=177, Evalue=6e-46,
Organism=Drosophila melanogaster, GI21355597, Length=123, Percent_Identity=73.1707317073171, Blast_Score=195, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 15231; Mature: 15100

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSDSVLNHYNNPRNVGTIDKNKKNVGTGLVGAPACGDVMRLQIEVDNNGCIVDAKFKT
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCC
FGCGSAIASSSLATEYLIGKSIEEAEKIKNTEIASTLCLPPIKMHCSMLAEDAIKAAIKD
CCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FREKQVTSSTEEAGNENTENKS
HHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure 
AYSDSVLNHYNNPRNVGTIDKNKKNVGTGLVGAPACGDVMRLQIEVDNNGCIVDAKFKT
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCC
FGCGSAIASSSLATEYLIGKSIEEAEKIKNTEIASTLCLPPIKMHCSMLAEDAIKAAIKD
CCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FREKQVTSSTEEAGNENTENKS
HHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]