Click here to switch to the map view.

The map label for this gene is atoS [C]

Identifier: 88608143

GI number: 88608143

Start: 297885

End: 300113

Strand: Direct

Name: atoS [C]

Synonym: NSE_0366

Alternate gene names: 88608143

Gene position: 297885-300113 (Clockwise)

Preceding gene: 88608232

Following gene: 88608761

Centisome position: 34.68

GC content: 38.09

Gene sequence:

>2229_bases
ATGAAAAGTAGATACACAGATGGTATCAAAAAGAACAAGCTGAACTTTGTTATCAGGTATCCGAGAAGATTTTTCTTAGT
TTTCATTTTGATGTTACTGCAGTTTCTGTGCGGTGCTCCAATTGTTTTGGGATTCAATTCAATAGATCTGTCAGGCGTTC
ACGAAATTAAAGGGCTTTTCTATGCATGCGGGATTATTATATTTTTTCTCCTCACTTACAACTTAAAGAAACTTCACTTA
GTACTTGCAGCAGCGGAATTTCAAAATATGTTCTACTCAAATGCTGCAAAGGCACTGACCGAATTTTACTTGATCATCAC
CAATAATGGCGAGGTAGTATATAGGGATGAGAGAACGAAGATAAAAAATCTACAATCCCTTTTAGGAGAGAAATACGAAA
AGTTTATTTCTGATATCAGGGAAGGGGTGCTGTATCACAGTTTTTCTTATGATGGACAGGTGGTAGAAATTACCCCAATG
ATTCGTCCAAAGGGGTATTTCATTGTTGCGGCCAGGAGGGTTGGTGAAAGAGAAATTTATGATGTGCTTTTACGAGAGGC
GGGGATTTCTTTGTATAGCGTCAGAGGTGATTCATTAAAGTACAGATGTGCTTCCTATTTCGAAGAGGCGAGTTATAAAA
AAACTTTTCTTGAGAATGAGCTTTACAGACTAACAGAGGTTTTTTTAACAGAGCAAAACCATAAAGGCCTCTTCCTGCAA
AACTACAGAAGGTGTTTCAATGACACACATTACGGAGTGTTAGTACCAAAGTTGAAAGAAATCAGAGAGCTAGCAAACAA
TGCGTCTATCGGTATTGTTTTAATGAGCAATGACTTAGAAATAATTAGCGCGAATGACGCTTTCTTTGATATATTCGAGA
AGGGAGATCAGATAAAGCAGTTTCTTCGTGACAAATTGAGTGATTTAAAGCGTGGAGGTGGACCGTCTATATTTAATTTT
TCCACGGAGAACGGTGATAGTGCACGACTTTACCTTTCAACTTGTGGTATTCTTAATATAGGGTTTCTCGTCGACCTAAG
CGAGTTAAGTGACTTGCAGAAAAAATTTCAGCATTCTCAAAAGATATTTTCTTTAGGTGAGTTGAGTGGTGGTATAGCTC
ACGACTTTAATAACATTCTCACTGCGATAATGGGCTTTGCAGAAATGCTGCTTGAAGATGTGCGACTAGAAAGCAAGCAC
TACTATAACGTTGCTCAGATAAGGTATAGCGCAAAAAAAGGTAGGGACTTGGTAAAGAAAATTTTGGCTTTTTCTCGAAA
ACAAACTCTGCATCCCGAGGTTTTGAGTATGGCAGAGGTTGTGAAAAGTATGAGGCAGTTTATAGAGAGGCTCGTTCCAG
AAAATATTAAGCTGACTTTTGTTATTAGGTCAGGTCTAAAAAACGTAAGAGTCGACAGGACAGAGATAGAGCAGAGTCTT
ATCAATTTAATAGTCAATGCACGTGATGCAATAGAAACGTGTGGGGAAATCACTGTTGAAATTGCAGAAACTTTCATAAA
CAAAAAATATGCTGTTCTTCCTGGTACTCAAAATGAGGAGGTTGTTTTAAAAGGAGAGTACATAAGCCTTACAGTTCGTG
ATAACGGTTGTGGAATAAACAAGGAGTTGCTGTCGAAAATTTTTGATCCTTTCTTTTCAACAAAAAGTGTAGATAAAGGA
ACAGGTTTAGGCCTTTCTACTGTTTATGGCATAATGAAGCAGATGAAGGGTTACATAAATGTTGAGAGCACCGAAGGCCA
GGGTTCCCTTTTTACACTATTGATCCCAGTTTCCTATGAAGATATCAGTAGTGATGCAAAAAAGGTTGATGAAGATTTGG
TTCCTTCAGAGAGAAGCAAAGGTGCAAAGATACTGCTAGTTGAAGATGAAAAAATTGTCAGAAATTTTTTGGTGAAAGCT
TTAACTCGCCAGGGTTTTAGTGTCATCGAGTACGAAAGTAGTAAGTCAGCTCTTGAAAAATTTGAAGAAGAAAAAAATAC
GGTTGCCCTCCTAATTACAGATGTCGTAATGCCCGGTATGGATGGTCCGGAAATGGTCAAGGAGATGAGAAAGCAGAAAG
CGGATCTCAAAGTTCTTTTCATGTCTGGGTACACGCGTGACAAGTTACATTTAGACAGTAAAAATCGTGATGAAATTTTT
GTAGCGAAGCCTTTTGGGATTAATGAGTTAATTTCTAAAATCATAAGCTTAACCGAAGGTGGGGGTTAG

Upstream 100 bases:

>100_bases
GCTACTATAGATGAATTAGCAGCGGAGAAGGAGATTTTGCTTATAGATAAGATGGTATCAGAGGAGAAAATAGATTATCT
AAAGCGAAAAGTGAAGGAAA

Downstream 100 bases:

>100_bases
AATGCATGAAAAATAAAACAAGAGTATCCGAGTACTATTTACCCCTTATGAAAAATGTATCGGGTGAGGTGAAGTTGCGC
TCGCACAAGTATTCCCTGCG

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 742; Mature: 742

Protein sequence:

>742_residues
MKSRYTDGIKKNKLNFVIRYPRRFFLVFILMLLQFLCGAPIVLGFNSIDLSGVHEIKGLFYACGIIIFFLLTYNLKKLHL
VLAAAEFQNMFYSNAAKALTEFYLIITNNGEVVYRDERTKIKNLQSLLGEKYEKFISDIREGVLYHSFSYDGQVVEITPM
IRPKGYFIVAARRVGEREIYDVLLREAGISLYSVRGDSLKYRCASYFEEASYKKTFLENELYRLTEVFLTEQNHKGLFLQ
NYRRCFNDTHYGVLVPKLKEIRELANNASIGIVLMSNDLEIISANDAFFDIFEKGDQIKQFLRDKLSDLKRGGGPSIFNF
STENGDSARLYLSTCGILNIGFLVDLSELSDLQKKFQHSQKIFSLGELSGGIAHDFNNILTAIMGFAEMLLEDVRLESKH
YYNVAQIRYSAKKGRDLVKKILAFSRKQTLHPEVLSMAEVVKSMRQFIERLVPENIKLTFVIRSGLKNVRVDRTEIEQSL
INLIVNARDAIETCGEITVEIAETFINKKYAVLPGTQNEEVVLKGEYISLTVRDNGCGINKELLSKIFDPFFSTKSVDKG
TGLGLSTVYGIMKQMKGYINVESTEGQGSLFTLLIPVSYEDISSDAKKVDEDLVPSERSKGAKILLVEDEKIVRNFLVKA
LTRQGFSVIEYESSKSALEKFEEEKNTVALLITDVVMPGMDGPEMVKEMRKQKADLKVLFMSGYTRDKLHLDSKNRDEIF
VAKPFGINELISKIISLTEGGG

Sequences:

>Translated_742_residues
MKSRYTDGIKKNKLNFVIRYPRRFFLVFILMLLQFLCGAPIVLGFNSIDLSGVHEIKGLFYACGIIIFFLLTYNLKKLHL
VLAAAEFQNMFYSNAAKALTEFYLIITNNGEVVYRDERTKIKNLQSLLGEKYEKFISDIREGVLYHSFSYDGQVVEITPM
IRPKGYFIVAARRVGEREIYDVLLREAGISLYSVRGDSLKYRCASYFEEASYKKTFLENELYRLTEVFLTEQNHKGLFLQ
NYRRCFNDTHYGVLVPKLKEIRELANNASIGIVLMSNDLEIISANDAFFDIFEKGDQIKQFLRDKLSDLKRGGGPSIFNF
STENGDSARLYLSTCGILNIGFLVDLSELSDLQKKFQHSQKIFSLGELSGGIAHDFNNILTAIMGFAEMLLEDVRLESKH
YYNVAQIRYSAKKGRDLVKKILAFSRKQTLHPEVLSMAEVVKSMRQFIERLVPENIKLTFVIRSGLKNVRVDRTEIEQSL
INLIVNARDAIETCGEITVEIAETFINKKYAVLPGTQNEEVVLKGEYISLTVRDNGCGINKELLSKIFDPFFSTKSVDKG
TGLGLSTVYGIMKQMKGYINVESTEGQGSLFTLLIPVSYEDISSDAKKVDEDLVPSERSKGAKILLVEDEKIVRNFLVKA
LTRQGFSVIEYESSKSALEKFEEEKNTVALLITDVVMPGMDGPEMVKEMRKQKADLKVLFMSGYTRDKLHLDSKNRDEIF
VAKPFGINELISKIISLTEGGG
>Mature_742_residues
MKSRYTDGIKKNKLNFVIRYPRRFFLVFILMLLQFLCGAPIVLGFNSIDLSGVHEIKGLFYACGIIIFFLLTYNLKKLHL
VLAAAEFQNMFYSNAAKALTEFYLIITNNGEVVYRDERTKIKNLQSLLGEKYEKFISDIREGVLYHSFSYDGQVVEITPM
IRPKGYFIVAARRVGEREIYDVLLREAGISLYSVRGDSLKYRCASYFEEASYKKTFLENELYRLTEVFLTEQNHKGLFLQ
NYRRCFNDTHYGVLVPKLKEIRELANNASIGIVLMSNDLEIISANDAFFDIFEKGDQIKQFLRDKLSDLKRGGGPSIFNF
STENGDSARLYLSTCGILNIGFLVDLSELSDLQKKFQHSQKIFSLGELSGGIAHDFNNILTAIMGFAEMLLEDVRLESKH
YYNVAQIRYSAKKGRDLVKKILAFSRKQTLHPEVLSMAEVVKSMRQFIERLVPENIKLTFVIRSGLKNVRVDRTEIEQSL
INLIVNARDAIETCGEITVEIAETFINKKYAVLPGTQNEEVVLKGEYISLTVRDNGCGINKELLSKIFDPFFSTKSVDKG
TGLGLSTVYGIMKQMKGYINVESTEGQGSLFTLLIPVSYEDISSDAKKVDEDLVPSERSKGAKILLVEDEKIVRNFLVKA
LTRQGFSVIEYESSKSALEKFEEEKNTVALLITDVVMPGMDGPEMVKEMRKQKADLKVLFMSGYTRDKLHLDSKNRDEIF
VAKPFGINELISKIISLTEGGG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=373, Percent_Identity=25.7372654155496, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=24.4094488188976, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=347, Percent_Identity=23.0547550432277, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI48994928, Length=417, Percent_Identity=27.0983213429257, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=263, Percent_Identity=27.7566539923954, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=29.7071129707113, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=157, Percent_Identity=33.7579617834395, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=26.1410788381743, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84296; Mature: 84296

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRYTDGIKKNKLNFVIRYPRRFFLVFILMLLQFLCGAPIVLGFNSIDLSGVHEIKGLF
CCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHH
YACGIIIFFLLTYNLKKLHLVLAAAEFQNMFYSNAAKALTEFYLIITNNGEVVYRDERTK
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEECCHHH
IKNLQSLLGEKYEKFISDIREGVLYHSFSYDGQVVEITPMIRPKGYFIVAARRVGEREIY
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCEEEEEECCCCHHHHH
DVLLREAGISLYSVRGDSLKYRCASYFEEASYKKTFLENELYRLTEVFLTEQNHKGLFLQ
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
NYRRCFNDTHYGVLVPKLKEIRELANNASIGIVLMSNDLEIISANDAFFDIFEKGDQIKQ
HHHHHHCCCCCEEECHHHHHHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHCCHHHHH
FLRDKLSDLKRGGGPSIFNFSTENGDSARLYLSTCGILNIGFLVDLSELSDLQKKFQHSQ
HHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCHHHHHHHEEHHHHHHHHHHHHHHH
KIFSLGELSGGIAHDFNNILTAIMGFAEMLLEDVRLESKHYYNVAQIRYSAKKGRDLVKK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEHHHEEECHHHHHHHHHH
ILAFSRKQTLHPEVLSMAEVVKSMRQFIERLVPENIKLTFVIRSGLKNVRVDRTEIEQSL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHH
INLIVNARDAIETCGEITVEIAETFINKKYAVLPGTQNEEVVLKGEYISLTVRDNGCGIN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEEEEEECCCCCCC
KELLSKIFDPFFSTKSVDKGTGLGLSTVYGIMKQMKGYINVESTEGQGSLFTLLIPVSYE
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECHH
DISSDAKKVDEDLVPSERSKGAKILLVEDEKIVRNFLVKALTRQGFSVIEYESSKSALEK
HHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHH
FEEEKNTVALLITDVVMPGMDGPEMVKEMRKQKADLKVLFMSGYTRDKLHLDSKNRDEIF
HHHCCCEEEEEEEHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCEE
VAKPFGINELISKIISLTEGGG
EECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKSRYTDGIKKNKLNFVIRYPRRFFLVFILMLLQFLCGAPIVLGFNSIDLSGVHEIKGLF
CCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHH
YACGIIIFFLLTYNLKKLHLVLAAAEFQNMFYSNAAKALTEFYLIITNNGEVVYRDERTK
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEECCHHH
IKNLQSLLGEKYEKFISDIREGVLYHSFSYDGQVVEITPMIRPKGYFIVAARRVGEREIY
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCEEEEEECCCCHHHHH
DVLLREAGISLYSVRGDSLKYRCASYFEEASYKKTFLENELYRLTEVFLTEQNHKGLFLQ
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
NYRRCFNDTHYGVLVPKLKEIRELANNASIGIVLMSNDLEIISANDAFFDIFEKGDQIKQ
HHHHHHCCCCCEEECHHHHHHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHCCHHHHH
FLRDKLSDLKRGGGPSIFNFSTENGDSARLYLSTCGILNIGFLVDLSELSDLQKKFQHSQ
HHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCHHHHHHHEEHHHHHHHHHHHHHHH
KIFSLGELSGGIAHDFNNILTAIMGFAEMLLEDVRLESKHYYNVAQIRYSAKKGRDLVKK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEHHHEEECHHHHHHHHHH
ILAFSRKQTLHPEVLSMAEVVKSMRQFIERLVPENIKLTFVIRSGLKNVRVDRTEIEQSL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHH
INLIVNARDAIETCGEITVEIAETFINKKYAVLPGTQNEEVVLKGEYISLTVRDNGCGIN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEEEEEECCCCCCC
KELLSKIFDPFFSTKSVDKGTGLGLSTVYGIMKQMKGYINVESTEGQGSLFTLLIPVSYE
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECHH
DISSDAKKVDEDLVPSERSKGAKILLVEDEKIVRNFLVKALTRQGFSVIEYESSKSALEK
HHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHH
FEEEKNTVALLITDVVMPGMDGPEMVKEMRKQKADLKVLFMSGYTRDKLHLDSKNRDEIF
HHHCCCEEEEEEEHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCEE
VAKPFGINELISKIISLTEGGG
EECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA