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The map label for this gene is yjcC [H]

Identifier: 88608099

GI number: 88608099

Start: 359143

End: 360159

Strand: Direct

Name: yjcC [H]

Synonym: NSE_0442

Alternate gene names: 88608099

Gene position: 359143-360159 (Clockwise)

Preceding gene: 88608065

Following gene: 88608079

Centisome position: 41.81

GC content: 36.97

Gene sequence:

>1017_bases
ATGCTTTCAGCTGGCCTAAATATCATAGCATTCAAGCCACCGGTTATCGTGATTCTTGAGAGTAATGGGAGCTCTGTGTG
GAGCATATATGAAAAGCTGACAGAGGTTGCTTCTTCTGTATTTCAGGAGTACGTGAGTTTTGCGGTAGGTTACTACGTTT
TTTCGTTTGAGGTACCAAATGAAGTGATAAGTAAGGCTTTTGCAGCTGTGTCTTTTGGTGAAAAAGAGGGTAGTGGGATT
GTTAGTTATGCGAGCTGTGCTTCAAGATTAAAAGAATTCTCGAATGCAGTTGCGAAGGCTACGGTTTTACACAATGCTCT
AAAAAACAACGAGTTATTGAACGTCTTTCAGCCAATTGTTGATACAGAGACCTCATCTGTAATTTTTAATGAATTCCTGC
TGAGGGTCAAAGGCGAAGAAAGCATTAGAGATTGTATAGTTGCGGCAGAAAAAACACATTTAATTTCTGTGGTGGATAAA
TTTGTTTTCAAGCGCGTTGTTGAACTTCTTGAACGTCATAGTGATCTAAGATTGTCATTTAACCTTTCTATGTTAAGTGC
AAGTGACGAACTGCAAACAGAAGAATTTTTAAAATCTTTTGCTACACTGCAATTTATTGCGAAGAGGCTTGTTGTAGAGA
TTACAGAGGGGGTACTGTTGCATGATACGGATAGGATGTTTGATTTTATCTTTAAGTTGAAATCTCTTGGATGTGCTATA
GCTTTAGATGATTTCGGAAAGAATTTTTATCTTCCTTTCTCGGAGCTTGAGAAGTTGCCAATAGATTATTTGAAGCTTGA
TAGGGAATTTGCTGGGAAAATTAAAACTAGCAAGAATGCTTCTATTTTTATTAAGAATATTCTTGAGATTGCAAATAATC
TAAATATCAAGGTAGTTGCAGAGTTTGTCGAAGATAAGAGCGTGTTTGATTTATTCAAGGAATTGGGAATCAGATATATG
CAAGGTAACTATCTACATGGAGCCAGTCCAGAGTTAAAAGATACGGTTAATGCATGA

Upstream 100 bases:

>100_bases
TGTTTTTCTTGTCGCGAAAATATTGAATCCTCTTGCTTATAAGGTTTTTTCTTATGAACAAAGGAAATGTGAGGGGTATC
TAGTTGAGTTGGAAAAACAA

Downstream 100 bases:

>100_bases
AAAAAATTTCTATTTTAGGTTCAACTGGTTCGGTTGGCTGTCAGTCTGTTGATGTAGTTTCCCGTTTCTATAGCGGTACA
ATTAAGGTTGACGCGCTGAG

Product: EAL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLSAGLNIIAFKPPVIVILESNGSSVWSIYEKLTEVASSVFQEYVSFAVGYYVFSFEVPNEVISKAFAAVSFGEKEGSGI
VSYASCASRLKEFSNAVAKATVLHNALKNNELLNVFQPIVDTETSSVIFNEFLLRVKGEESIRDCIVAAEKTHLISVVDK
FVFKRVVELLERHSDLRLSFNLSMLSASDELQTEEFLKSFATLQFIAKRLVVEITEGVLLHDTDRMFDFIFKLKSLGCAI
ALDDFGKNFYLPFSELEKLPIDYLKLDREFAGKIKTSKNASIFIKNILEIANNLNIKVVAEFVEDKSVFDLFKELGIRYM
QGNYLHGASPELKDTVNA

Sequences:

>Translated_338_residues
MLSAGLNIIAFKPPVIVILESNGSSVWSIYEKLTEVASSVFQEYVSFAVGYYVFSFEVPNEVISKAFAAVSFGEKEGSGI
VSYASCASRLKEFSNAVAKATVLHNALKNNELLNVFQPIVDTETSSVIFNEFLLRVKGEESIRDCIVAAEKTHLISVVDK
FVFKRVVELLERHSDLRLSFNLSMLSASDELQTEEFLKSFATLQFIAKRLVVEITEGVLLHDTDRMFDFIFKLKSLGCAI
ALDDFGKNFYLPFSELEKLPIDYLKLDREFAGKIKTSKNASIFIKNILEIANNLNIKVVAEFVEDKSVFDLFKELGIRYM
QGNYLHGASPELKDTVNA
>Mature_338_residues
MLSAGLNIIAFKPPVIVILESNGSSVWSIYEKLTEVASSVFQEYVSFAVGYYVFSFEVPNEVISKAFAAVSFGEKEGSGI
VSYASCASRLKEFSNAVAKATVLHNALKNNELLNVFQPIVDTETSSVIFNEFLLRVKGEESIRDCIVAAEKTHLISVVDK
FVFKRVVELLERHSDLRLSFNLSMLSASDELQTEEFLKSFATLQFIAKRLVVEITEGVLLHDTDRMFDFIFKLKSLGCAI
ALDDFGKNFYLPFSELEKLPIDYLKLDREFAGKIKTSKNASIFIKNILEIANNLNIKVVAEFVEDKSVFDLFKELGIRYM
QGNYLHGASPELKDTVNA

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=30.1587301587302, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788849, Length=255, Percent_Identity=30.9803921568627, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87081921, Length=337, Percent_Identity=27.5964391691395, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788502, Length=240, Percent_Identity=31.25, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI226510982, Length=316, Percent_Identity=24.3670886075949, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787541, Length=230, Percent_Identity=29.5652173913043, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87081845, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082096, Length=290, Percent_Identity=25.8620689655172, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081980, Length=226, Percent_Identity=28.7610619469027, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=26.1603375527426, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786507, Length=233, Percent_Identity=26.6094420600858, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787055, Length=260, Percent_Identity=27.3076923076923, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 37916; Mature: 37916

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAGLNIIAFKPPVIVILESNGSSVWSIYEKLTEVASSVFQEYVSFAVGYYVFSFEVPN
CCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCH
EVISKAFAAVSFGEKEGSGIVSYASCASRLKEFSNAVAKATVLHNALKNNELLNVFQPIV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DTETSSVIFNEFLLRVKGEESIRDCIVAAEKTHLISVVDKFVFKRVVELLERHSDLRLSF
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NLSMLSASDELQTEEFLKSFATLQFIAKRLVVEITEGVLLHDTDRMFDFIFKLKSLGCAI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCEE
ALDDFGKNFYLPFSELEKLPIDYLKLDREFAGKIKTSKNASIFIKNILEIANNLNIKVVA
EEECCCCCCCCCHHHHHHCCHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEHH
EFVEDKSVFDLFKELGIRYMQGNYLHGASPELKDTVNA
HHHHCHHHHHHHHHHCCEEECCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MLSAGLNIIAFKPPVIVILESNGSSVWSIYEKLTEVASSVFQEYVSFAVGYYVFSFEVPN
CCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCH
EVISKAFAAVSFGEKEGSGIVSYASCASRLKEFSNAVAKATVLHNALKNNELLNVFQPIV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DTETSSVIFNEFLLRVKGEESIRDCIVAAEKTHLISVVDKFVFKRVVELLERHSDLRLSF
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NLSMLSASDELQTEEFLKSFATLQFIAKRLVVEITEGVLLHDTDRMFDFIFKLKSLGCAI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCEE
ALDDFGKNFYLPFSELEKLPIDYLKLDREFAGKIKTSKNASIFIKNILEIANNLNIKVVA
EEECCCCCCCCCHHHHHHCCHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEHH
EFVEDKSVFDLFKELGIRYMQGNYLHGASPELKDTVNA
HHHHCHHHHHHHHHHCCEEECCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]