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The map label for this gene is ppnK [H]

Identifier: 88608069

GI number: 88608069

Start: 253032

End: 253793

Strand: Reverse

Name: ppnK [H]

Synonym: NSE_0310

Alternate gene names: 88608069

Gene position: 253793-253032 (Counterclockwise)

Preceding gene: 88608660

Following gene: 88608331

Centisome position: 29.54

GC content: 42.26

Gene sequence:

>762_bases
GTGTTTTATTCTTCTTCTGGCTCAGAAAAGGCAACATCTGTTGCCGCGTTTATTAGTTCGCGTTACGGAATAAAGTGCAT
TGACGCTCCAGAGGCAGTAGACCCATCGATGATTCTCGCTTTAGGCGGAGATGGATTCATGCTTGATACTCTGCATAGCA
CAATAGAAACCCAGATACCTGTTTATGGGATAAATTGCGGGAATGTTGGCTTTTTACTGAACAAATTTCATCCAAACCAC
TTACTCGAAGATATAGAAAGCGCAGGCACCCATATCCTACCCATTCTAAATGCTGAGCTTTTCGATGGAAAGGGCAGTAG
GATGGTAAATGCGATAAATGATTGTTATTTCCTTAGAAGCCACACAAAAGCAGCAAAGCTCGGGATAACGGTGGACGGAG
AAATCCTTACCGAGAGTTTTGTCGGGGACGGGCTGATCATCTCAACTCCCACAGGAAGTACAGCTTATAATTCAGCTATA
GGTGGAGCAGTGTTATCACTCAGCTCAAATTGCATAATCCTAACAGGAATTAATGCATTTACACCAAAAGGATTTAAGAG
TCTTGTCCTACCAAGAGATAGTATAATAGAAATCAAAATCCACCACCATGATAGAAGGCCTGTGATTGCTGCAGCGGACG
CACAAGTCTTTTTAGGAGTAGAAAGAGCAAGAATATCCATAGATAAAAAGAAGACTGTTTCCGTGTTGTTTGCAGCCAGC
GAGAGTCTCCATAAAAAAATTATGATGGCCCAATTCCGTTGA

Upstream 100 bases:

>100_bases
TTTTCATTAATGACGTGTGTGTAGGTGGCTTTGATGATCTCAACAGCCTAAACGAGAGTGGCAAGCTCAATGAGCTCTTA
TTTTTGAACAATCAGTAAAG

Downstream 100 bases:

>100_bases
TGAAAGCGATCGGTGTCACGGGAAGGATGGCTTCGGGCAAAACGTATTTTTCCTCTATTTTATCCCGTTCACTGCGCTGT
AAAGTATTTGATGCAGATAA

Product: putative ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MFYSSSGSEKATSVAAFISSRYGIKCIDAPEAVDPSMILALGGDGFMLDTLHSTIETQIPVYGINCGNVGFLLNKFHPNH
LLEDIESAGTHILPILNAELFDGKGSRMVNAINDCYFLRSHTKAAKLGITVDGEILTESFVGDGLIISTPTGSTAYNSAI
GGAVLSLSSNCIILTGINAFTPKGFKSLVLPRDSIIEIKIHHHDRRPVIAAADAQVFLGVERARISIDKKKTVSVLFAAS
ESLHKKIMMAQFR

Sequences:

>Translated_253_residues
MFYSSSGSEKATSVAAFISSRYGIKCIDAPEAVDPSMILALGGDGFMLDTLHSTIETQIPVYGINCGNVGFLLNKFHPNH
LLEDIESAGTHILPILNAELFDGKGSRMVNAINDCYFLRSHTKAAKLGITVDGEILTESFVGDGLIISTPTGSTAYNSAI
GGAVLSLSSNCIILTGINAFTPKGFKSLVLPRDSIIEIKIHHHDRRPVIAAADAQVFLGVERARISIDKKKTVSVLFAAS
ESLHKKIMMAQFR
>Mature_253_residues
MFYSSSGSEKATSVAAFISSRYGIKCIDAPEAVDPSMILALGGDGFMLDTLHSTIETQIPVYGINCGNVGFLLNKFHPNH
LLEDIESAGTHILPILNAELFDGKGSRMVNAINDCYFLRSHTKAAKLGITVDGEILTESFVGDGLIISTPTGSTAYNSAI
GGAVLSLSSNCIILTGINAFTPKGFKSLVLPRDSIIEIKIHHHDRRPVIAAADAQVFLGVERARISIDKKKTVSVLFAAS
ESLHKKIMMAQFR

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=192, Percent_Identity=31.7708333333333, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325068, Length=174, Percent_Identity=32.7586206896552, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 27169; Mature: 27169

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYSSSGSEKATSVAAFISSRYGIKCIDAPEAVDPSMILALGGDGFMLDTLHSTIETQIP
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCC
VYGINCGNVGFLLNKFHPNHLLEDIESAGTHILPILNAELFDGKGSRMVNAINDCYFLRS
EEEECCCCHHHEEECCCHHHHHHHHHHCCCEEEEEECCEEECCCCCHHHHHHHHHHEECC
HTKAAKLGITVDGEILTESFVGDGLIISTPTGSTAYNSAIGGAVLSLSSNCIILTGINAF
CCCCEEEEEEECCHHHHHHHCCCCEEEECCCCCCHHHHHHCCEEEEECCCEEEEECCCCC
TPKGFKSLVLPRDSIIEIKIHHHDRRPVIAAADAQVFLGVERARISIDKKKTVSVLFAAS
CCCCCCEEECCCCCEEEEEEEECCCCCEEEECCCEEEEEEEHHEEEECCCCEEEEEEECH
ESLHKKIMMAQFR
HHHHHHHHHHCCC
>Mature Secondary Structure
MFYSSSGSEKATSVAAFISSRYGIKCIDAPEAVDPSMILALGGDGFMLDTLHSTIETQIP
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCC
VYGINCGNVGFLLNKFHPNHLLEDIESAGTHILPILNAELFDGKGSRMVNAINDCYFLRS
EEEECCCCHHHEEECCCHHHHHHHHHHCCCEEEEEECCEEECCCCCHHHHHHHHHHEECC
HTKAAKLGITVDGEILTESFVGDGLIISTPTGSTAYNSAIGGAVLSLSSNCIILTGINAF
CCCCEEEEEEECCHHHHHHHCCCCEEEECCCCCCHHHHHHCCEEEEECCCEEEEECCCCC
TPKGFKSLVLPRDSIIEIKIHHHDRRPVIAAADAQVFLGVERARISIDKKKTVSVLFAAS
CCCCCCEEECCCCCEEEEEEEECCCCCEEEECCCEEEEEEEHHEEEECCCCEEEEEEECH
ESLHKKIMMAQFR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA