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The map label for this gene is dapA

Identifier: 88608025

GI number: 88608025

Start: 822373

End: 823299

Strand: Direct

Name: dapA

Synonym: NSE_0929

Alternate gene names: 88608025

Gene position: 822373-823299 (Clockwise)

Preceding gene: 88608190

Following gene: 88608628

Centisome position: 95.74

GC content: 39.59

Gene sequence:

>927_bases
ATGCAGGGATTAAGATCAATCTTCAAAGGGATTTTCACTGCTATAATCACACCTTTTAAACGCAACACTCTGGATGTAGA
AAGCTTAGAACGATTAATCGAAATTCAAGTAGCTAGTGCCGTAGATGGTATCGTAATAGCGGACTCGACCGGAGAAGGAC
ATTCATTATCTCAATCGGAGTATTGTACCCTGGTAAAAAACGTAGCAGCAGTGCTTAAAAATAGGGTGCCTCTAGTTGTA
AGTGTGCCACACTGTTCTACGACACAAGCTATCGATGTAATAACTCACCTAAAAAACAAAACAATTGAAGCATTCCTTGT
TGCCGCACCGTATTATCTACGCCCACAACAAGAAGGAATCTTTGAGCATTATCGACAGATTACAAACAAAACAAAGGCGA
ACATTATCATGTGCAACATACCACACAGATGTGCTATCAATGTAGAAAATGCAACAACACTGAAAATCATGGATCTGCCG
GCTATATCAGCAATTGTTGATTTATCGGGAGATCTTGAATATCCAACAATACTGCGTAGAGAAAATGACCGCGTACCCAT
ACTTACAGGGAATGATACGACATATGCAGCCCATAGACTCAACGGAGGAGATGGAATAGTATCCACACTAAGCAACCTAA
TTCCAAAAGAAATGGTCACGTTGGAGAGAGCAATCTATAAAGGTAACTACGAAAACATCAAGAAGTTACATAAACTTATT
TTTCCACTTGCCAAATCTATGTCCTGCGAGACTAACCCAATACCTTTAAAATATGCCGTCAGTTGCATCTACAAGTACGT
CACACCAAATGTCAGGCTCCCACTGACTGATGCAACTACGTTAACTAGGCAGTTAATACATACTCTTCTAAGTAACTTAG
AAAGGGAGAAACAAGAACACGAAATTTTATCCCTGATACAAAGTTGA

Upstream 100 bases:

>100_bases
GGAACAGATAACTAAAGTCCTTTTTATCAGCGAAAGTCAAAAATTTTATTTCTTTTAAGTAAGGTGCTACTAATAATTTT
AGACGCAAATTTTATCTGGA

Downstream 100 bases:

>100_bases
TTGGAAAAAAGATTCAATCCTAACGAATACTTCTCCCCAAACATTCTCTAGGCAGAGCATTCACATCTATCCGGCTTTCT
AAGCCAGATATCTTCCTCTA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MQGLRSIFKGIFTAIITPFKRNTLDVESLERLIEIQVASAVDGIVIADSTGEGHSLSQSEYCTLVKNVAAVLKNRVPLVV
SVPHCSTTQAIDVITHLKNKTIEAFLVAAPYYLRPQQEGIFEHYRQITNKTKANIIMCNIPHRCAINVENATTLKIMDLP
AISAIVDLSGDLEYPTILRRENDRVPILTGNDTTYAAHRLNGGDGIVSTLSNLIPKEMVTLERAIYKGNYENIKKLHKLI
FPLAKSMSCETNPIPLKYAVSCIYKYVTPNVRLPLTDATTLTRQLIHTLLSNLEREKQEHEILSLIQS

Sequences:

>Translated_308_residues
MQGLRSIFKGIFTAIITPFKRNTLDVESLERLIEIQVASAVDGIVIADSTGEGHSLSQSEYCTLVKNVAAVLKNRVPLVV
SVPHCSTTQAIDVITHLKNKTIEAFLVAAPYYLRPQQEGIFEHYRQITNKTKANIIMCNIPHRCAINVENATTLKIMDLP
AISAIVDLSGDLEYPTILRRENDRVPILTGNDTTYAAHRLNGGDGIVSTLSNLIPKEMVTLERAIYKGNYENIKKLHKLI
FPLAKSMSCETNPIPLKYAVSCIYKYVTPNVRLPLTDATTLTRQLIHTLLSNLEREKQEHEILSLIQS
>Mature_308_residues
MQGLRSIFKGIFTAIITPFKRNTLDVESLERLIEIQVASAVDGIVIADSTGEGHSLSQSEYCTLVKNVAAVLKNRVPLVV
SVPHCSTTQAIDVITHLKNKTIEAFLVAAPYYLRPQQEGIFEHYRQITNKTKANIIMCNIPHRCAINVENATTLKIMDLP
AISAIVDLSGDLEYPTILRRENDRVPILTGNDTTYAAHRLNGGDGIVSTLSNLIPKEMVTLERAIYKGNYENIKKLHKLI
FPLAKSMSCETNPIPLKYAVSCIYKYVTPNVRLPLTDATTLTRQLIHTLLSNLEREKQEHEILSLIQS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=252, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788823, Length=286, Percent_Identity=26.5734265734266, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789620, Length=232, Percent_Identity=26.2931034482759, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082415, Length=293, Percent_Identity=23.2081911262799, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786463, Length=254, Percent_Identity=20.4724409448819, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 34377; Mature: 34377

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLRSIFKGIFTAIITPFKRNTLDVESLERLIEIQVASAVDGIVIADSTGEGHSLSQSE
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHH
YCTLVKNVAAVLKNRVPLVVSVPHCSTTQAIDVITHLKNKTIEAFLVAAPYYLRPQQEGI
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHEEHEEECCCEECCCCCHH
FEHYRQITNKTKANIIMCNIPHRCAINVENATTLKIMDLPAISAIVDLSGDLEYPTILRR
HHHHHHHHCCCCCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHCCCCCCCCCHHEEC
ENDRVPILTGNDTTYAAHRLNGGDGIVSTLSNLIPKEMVTLERAIYKGNYENIKKLHKLI
CCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FPLAKSMSCETNPIPLKYAVSCIYKYVTPNVRLPLTDATTLTRQLIHTLLSNLEREKQEH
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
EILSLIQS
HHHHHHCC
>Mature Secondary Structure
MQGLRSIFKGIFTAIITPFKRNTLDVESLERLIEIQVASAVDGIVIADSTGEGHSLSQSE
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHH
YCTLVKNVAAVLKNRVPLVVSVPHCSTTQAIDVITHLKNKTIEAFLVAAPYYLRPQQEGI
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHEEHEEECCCEECCCCCHH
FEHYRQITNKTKANIIMCNIPHRCAINVENATTLKIMDLPAISAIVDLSGDLEYPTILRR
HHHHHHHHCCCCCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHCCCCCCCCCHHEEC
ENDRVPILTGNDTTYAAHRLNGGDGIVSTLSNLIPKEMVTLERAIYKGNYENIKKLHKLI
CCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FPLAKSMSCETNPIPLKYAVSCIYKYVTPNVRLPLTDATTLTRQLIHTLLSNLEREKQEH
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
EILSLIQS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA