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The map label for this gene is ywlC [H]

Identifier: 88607846

GI number: 88607846

Start: 824480

End: 825082

Strand: Direct

Name: ywlC [H]

Synonym: APH_0782

Alternate gene names: 88607846

Gene position: 824480-825082 (Clockwise)

Preceding gene: 88607268

Following gene: 88607018

Centisome position: 56.04

GC content: 40.3

Gene sequence:

>603_bases
ATGGTTGAAGAAATAGTAAATGCGCTTAGAAATGAGGAAATAGTATGTTTCCCCACTGAAACTCTGTACGCTTTAGCATG
TAATGCTTTTAGTGAACGCGCAGTTGCTAAACTGTACGACATAAAACGTCGTTTATATGATAAACCTTTCTCTCTAATGT
TAGGTGATATTCAGCAAGTTAAGAAGTTTTCTAATATGAAAAATACAGACTTGAGGATAATGGAAATGTTATCACCGGGG
CCGATAACCTTCATACTCCCTCTGCATTATGCACAAAACTTGCCAAGACGCTTCTTCAAAGATACCCTGGGCGTGAGAAT
ACCTGATCATGCGCTGGCGTGTAATATACTCAGTAGGTTTGAGTTCCCTGTTGTAGCTACTAGCGCGAATTTGTCTGGTG
AGCGCGATGCTCTAAAGGCCTCTGATATTCCTGAAGAACTTAGAATGCATGTTTCTAAGTTATGGGAGGATGATAGCTCT
GTTAGCGGAATGTGTTCTACAGTATTTGACATGGTATCGCAGAAAATACTGAGAACTGGTATGCTACCGAGTAGCAAAAT
TCTTGATGCTATTAACCGTGGAAAAACAACATGGACACAGTAG

Upstream 100 bases:

>100_bases
CTGAATGTGATACCCTAATACATGGAGATGTCCTTTAAAGACCTAACAACTTCATTATCGGCTACCAGCAGGCTTATAGT
AACTATGTATATTGGTATAT

Downstream 100 bases:

>100_bases
TTGGACATAGTGCTCAAAAAGAGACTCTTTGGCAAAATCGTGAAGTCAACACCTGGCTTTTGTGCGGGAAAAGAGGTATC
GGTAAAGCAACTTTATCGCA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVEEIVNALRNEEIVCFPTETLYALACNAFSERAVAKLYDIKRRLYDKPFSLMLGDIQQVKKFSNMKNTDLRIMEMLSPG
PITFILPLHYAQNLPRRFFKDTLGVRIPDHALACNILSRFEFPVVATSANLSGERDALKASDIPEELRMHVSKLWEDDSS
VSGMCSTVFDMVSQKILRTGMLPSSKILDAINRGKTTWTQ

Sequences:

>Translated_200_residues
MVEEIVNALRNEEIVCFPTETLYALACNAFSERAVAKLYDIKRRLYDKPFSLMLGDIQQVKKFSNMKNTDLRIMEMLSPG
PITFILPLHYAQNLPRRFFKDTLGVRIPDHALACNILSRFEFPVVATSANLSGERDALKASDIPEELRMHVSKLWEDDSS
VSGMCSTVFDMVSQKILRTGMLPSSKILDAINRGKTTWTQ
>Mature_200_residues
MVEEIVNALRNEEIVCFPTETLYALACNAFSERAVAKLYDIKRRLYDKPFSLMLGDIQQVKKFSNMKNTDLRIMEMLSPG
PITFILPLHYAQNLPRRFFKDTLGVRIPDHALACNILSRFEFPVVATSANLSGERDALKASDIPEELRMHVSKLWEDDSS
VSGMCSTVFDMVSQKILRTGMLPSSKILDAINRGKTTWTQ

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=171, Percent_Identity=30.4093567251462, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI2367210, Length=135, Percent_Identity=34.8148148148148, Blast_Score=80, Evalue=7e-17,
Organism=Escherichia coli, GI87081864, Length=156, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=207, Percent_Identity=26.5700483091787, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI78707274, Length=134, Percent_Identity=30.5970149253731, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 22708; Mature: 22708

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEEIVNALRNEEIVCFPTETLYALACNAFSERAVAKLYDIKRRLYDKPFSLMLGDIQQV
CHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KKFSNMKNTDLRIMEMLSPGPITFILPLHYAQNLPRRFFKDTLGVRIPDHALACNILSRF
HHHHCCCCCCHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
EFPVVATSANLSGERDALKASDIPEELRMHVSKLWEDDSSVSGMCSTVFDMVSQKILRTG
CCCEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
MLPSSKILDAINRGKTTWTQ
CCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVEEIVNALRNEEIVCFPTETLYALACNAFSERAVAKLYDIKRRLYDKPFSLMLGDIQQV
CHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KKFSNMKNTDLRIMEMLSPGPITFILPLHYAQNLPRRFFKDTLGVRIPDHALACNILSRF
HHHHCCCCCCHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
EFPVVATSANLSGERDALKASDIPEELRMHVSKLWEDDSSVSGMCSTVFDMVSQKILRTG
CCCEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
MLPSSKILDAINRGKTTWTQ
CCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]