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The map label for this gene is dnaX [H]

Identifier: 88607018

GI number: 88607018

Start: 825070

End: 825948

Strand: Direct

Name: dnaX [H]

Synonym: APH_0783

Alternate gene names: 88607018

Gene position: 825070-825948 (Clockwise)

Preceding gene: 88607846

Following gene: 88606926

Centisome position: 56.08

GC content: 38.45

Gene sequence:

>879_bases
ATGGACACAGTAGTTGGACATAGTGCTCAAAAAGAGACTCTTTGGCAAAATCGTGAAGTCAACACCTGGCTTTTGTGCGG
GAAAAGAGGTATCGGTAAAGCAACTTTATCGCATGCTTATGCAAGGTTTCTTACTCGCTCTGATTCTTTGGATTCTCATC
CAGACGTAGCTATCATAGATGATGAAACATCACCTATAGGTATAGATAAGATCAGAAAAATTAAGCACTTCTTACACATG
TCGCCGATAAGTGCAGAACGTAAGATAGTGATACTTGATAGCATTGATGGGCTAAACAGCAACACGATAAACTCCATGCT
CAAGATCTTGGAAGAACCGCCACAACACTCACTTATCTTGATAATTAGTCACAACCTATATAGCGTGCCTATAGTGATAA
GGTCTAGGTGCATGATTCTTTCATTCTCTCAGCTTAGTCTTGAGGAAACAAGACAAGTAATAGGATTAAAATTTCCCGAT
ATGAACTTAGAAGATAAAGCAGTAGCTTTATATCCTGGCATTCCAGGAATGGTATCTGAAGACATAGACAAAGAAATAAC
TCTGTACGAGAACATAATTGACTTGATACAGAAAAAAAACGTTTCTGACACCATAGGAAACGTGCTGGAAACAGAACTTC
CCATGCACAAGATAGAGTACCTATCACTTAAAGCGATATATGACACAATTCTGAGCACACTTAGGTTGCACGAAAGCAAC
ACCAATTACGTGACTGAGGCAAATATACTTGCAATGTTGGATAAGTACTCAAAAGCACAGGAGATTTTTGCTACCGCGCG
AAAGTTACATATACATAGGGAAGCAACCCTATTTAGAATAGCTGAGATTATATCAAATCTTCTCAAATCCAAAAAATAG

Upstream 100 bases:

>100_bases
TGTGTTCTACAGTATTTGACATGGTATCGCAGAAAATACTGAGAACTGGTATGCTACCGAGTAGCAAAATTCTTGATGCT
ATTAACCGTGGAAAAACAAC

Downstream 100 bases:

>100_bases
GGATATTGCCTAGTGTTCATGTTCTCAATTATTATGTTCTTTACCTAAGTACGCTGTCTTTACATGATTTTGTGGCAAAA
AGTCGTCCATGCTTAATAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDTVVGHSAQKETLWQNREVNTWLLCGKRGIGKATLSHAYARFLTRSDSLDSHPDVAIIDDETSPIGIDKIRKIKHFLHM
SPISAERKIVILDSIDGLNSNTINSMLKILEEPPQHSLILIISHNLYSVPIVIRSRCMILSFSQLSLEETRQVIGLKFPD
MNLEDKAVALYPGIPGMVSEDIDKEITLYENIIDLIQKKNVSDTIGNVLETELPMHKIEYLSLKAIYDTILSTLRLHESN
TNYVTEANILAMLDKYSKAQEIFATARKLHIHREATLFRIAEIISNLLKSKK

Sequences:

>Translated_292_residues
MDTVVGHSAQKETLWQNREVNTWLLCGKRGIGKATLSHAYARFLTRSDSLDSHPDVAIIDDETSPIGIDKIRKIKHFLHM
SPISAERKIVILDSIDGLNSNTINSMLKILEEPPQHSLILIISHNLYSVPIVIRSRCMILSFSQLSLEETRQVIGLKFPD
MNLEDKAVALYPGIPGMVSEDIDKEITLYENIIDLIQKKNVSDTIGNVLETELPMHKIEYLSLKAIYDTILSTLRLHESN
TNYVTEANILAMLDKYSKAQEIFATARKLHIHREATLFRIAEIISNLLKSKK
>Mature_292_residues
MDTVVGHSAQKETLWQNREVNTWLLCGKRGIGKATLSHAYARFLTRSDSLDSHPDVAIIDDETSPIGIDKIRKIKHFLHM
SPISAERKIVILDSIDGLNSNTINSMLKILEEPPQHSLILIISHNLYSVPIVIRSRCMILSFSQLSLEETRQVIGLKFPD
MNLEDKAVALYPGIPGMVSEDIDKEITLYENIIDLIQKKNVSDTIGNVLETELPMHKIEYLSLKAIYDTILSTLRLHESN
TNYVTEANILAMLDKYSKAQEIFATARKLHIHREATLFRIAEIISNLLKSKK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=147, Percent_Identity=23.8095238095238, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 33084; Mature: 33084

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTVVGHSAQKETLWQNREVNTWLLCGKRGIGKATLSHAYARFLTRSDSLDSHPDVAIID
CCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEC
DETSPIGIDKIRKIKHFLHMSPISAERKIVILDSIDGLNSNTINSMLKILEEPPQHSLIL
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
IISHNLYSVPIVIRSRCMILSFSQLSLEETRQVIGLKFPDMNLEDKAVALYPGIPGMVSE
EEECCCEECHHHHHCCCCEEEHHHHCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHH
DIDKEITLYENIIDLIQKKNVSDTIGNVLETELPMHKIEYLSLKAIYDTILSTLRLHESN
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TNYVTEANILAMLDKYSKAQEIFATARKLHIHREATLFRIAEIISNLLKSKK
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTVVGHSAQKETLWQNREVNTWLLCGKRGIGKATLSHAYARFLTRSDSLDSHPDVAIID
CCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEC
DETSPIGIDKIRKIKHFLHMSPISAERKIVILDSIDGLNSNTINSMLKILEEPPQHSLIL
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
IISHNLYSVPIVIRSRCMILSFSQLSLEETRQVIGLKFPDMNLEDKAVALYPGIPGMVSE
EEECCCEECHHHHHCCCCEEEHHHHCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHH
DIDKEITLYENIIDLIQKKNVSDTIGNVLETELPMHKIEYLSLKAIYDTILSTLRLHESN
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TNYVTEANILAMLDKYSKAQEIFATARKLHIHREATLFRIAEIISNLLKSKK
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]