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The map label for this gene is yaeL [C]

Identifier: 88606695

GI number: 88606695

Start: 1279764

End: 1280852

Strand: Reverse

Name: yaeL [C]

Synonym: APH_1211

Alternate gene names: 88606695

Gene position: 1280852-1279764 (Counterclockwise)

Preceding gene: 88607085

Following gene: 88607567

Centisome position: 87.06

GC content: 46.83

Gene sequence:

>1089_bases
ATGTTGTCCTTAGCGCGGGCTGTGAGCGCTTTTCAGGAGGGTTCTTTCTATGTGGCCTCTTTCCTCCTCGTGCTTTCTGT
TGTTGTCTTTATACACGAGTATGGGCATTACTGTGTGGCTAAGCTCTGCAAGGTCAAGGTTGAGACTTTTTCTCTAGGGT
TTGGGCCTGAGCTGTTCGGGATAACCGATGGATCTGGGACCAGGTGGAAATTTAGCCTGGTGCCTGTAGGGGGTTATGTC
AAGATGTTTGGTGACGCTCTAGACAGGGAGATGTCTGAAGAGGAGAAGCTTTGTGCCTTAAATGAGAAGCCTTTGTGGCA
GAGGTTTCTTATAGCTTTTGCAGGTCCGGCAGCAAATTTACTATTCTCTCTACTGGTTTTCTTTGTTCTTTTTAGTACTC
GTGGGGTTTTGAGCCCTATGCCAGTGGTGGGTAATGTGCTTGCGGGGAGCACTGCAGAGCTTGTAGGTCTTGAAGCTGGC
GATAGGATAGTATCAATAGATGGTAACGAAGTCGCTTGGTTTGAGGAGATAAGGCATTACATAGCTGGGGGGCAGGGTGA
GTATCTAACTATAGGGTTCTTGCGTAGTGGGGTATTGCATCATGTCACGATTGGGCCAGAGGAGTGGTCTAGTGGGGCGC
GAAAGCTAGGTATTTCCGCTAGTTCGTTACCGATGGATAGTCAAAGTAGGCGCCTTCCGGTTCTTAGTGCTGCAAACGAG
GCTTTTTTGTGTACTTACAGGATTGTAAAGATTACTCTTATGGCTGTTGTTCAGCTGGTTACGGGTTCCCGCAGTGTTGA
TGAGCTTGGTGGGCCAGTCCGTATAGCAAAGCATTCTGGTGATGCGATACGGCAGAAGGAAGGCCTTCGTTTTGTAGGTC
TTATATCTGCAAATTTAGGTGTAATAAATTTATTGCCGTTACCAATGCTAGACGGGGGCTTCATGTTGCAGTATGCTCTG
CAAGGGATTTTTCGGCGCAAGACCTTTAACCCTAGGCATTGTAGTATAGTGATGGTCGTAGGGTTTATTCTTCTTGTATC
TCTGATGGTTTTTGTAACCTTCAATGACGTCAAGAGCATTTTGAAATGA

Upstream 100 bases:

>100_bases
TGTGGCTCCTATATTGAAACTTTATACGGCACAATAGTGTTGTCAAGGATATAAATATAGTATAACATGCTCCTGATTTT
TGAGCTTGTTGAGTGGGCTT

Downstream 100 bases:

>100_bases
GACATATGAGATATTTTTTTGTTTTAGTCCTGATGGCAACGATGTTTGCCTCGGTGAGACCGGCGGTTGCAGATAGTGTG
CAAAAAGTACGTATAGAGGG

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MLSLARAVSAFQEGSFYVASFLLVLSVVVFIHEYGHYCVAKLCKVKVETFSLGFGPELFGITDGSGTRWKFSLVPVGGYV
KMFGDALDREMSEEEKLCALNEKPLWQRFLIAFAGPAANLLFSLLVFFVLFSTRGVLSPMPVVGNVLAGSTAELVGLEAG
DRIVSIDGNEVAWFEEIRHYIAGGQGEYLTIGFLRSGVLHHVTIGPEEWSSGARKLGISASSLPMDSQSRRLPVLSAANE
AFLCTYRIVKITLMAVVQLVTGSRSVDELGGPVRIAKHSGDAIRQKEGLRFVGLISANLGVINLLPLPMLDGGFMLQYAL
QGIFRRKTFNPRHCSIVMVVGFILLVSLMVFVTFNDVKSILK

Sequences:

>Translated_362_residues
MLSLARAVSAFQEGSFYVASFLLVLSVVVFIHEYGHYCVAKLCKVKVETFSLGFGPELFGITDGSGTRWKFSLVPVGGYV
KMFGDALDREMSEEEKLCALNEKPLWQRFLIAFAGPAANLLFSLLVFFVLFSTRGVLSPMPVVGNVLAGSTAELVGLEAG
DRIVSIDGNEVAWFEEIRHYIAGGQGEYLTIGFLRSGVLHHVTIGPEEWSSGARKLGISASSLPMDSQSRRLPVLSAANE
AFLCTYRIVKITLMAVVQLVTGSRSVDELGGPVRIAKHSGDAIRQKEGLRFVGLISANLGVINLLPLPMLDGGFMLQYAL
QGIFRRKTFNPRHCSIVMVVGFILLVSLMVFVTFNDVKSILK
>Mature_362_residues
MLSLARAVSAFQEGSFYVASFLLVLSVVVFIHEYGHYCVAKLCKVKVETFSLGFGPELFGITDGSGTRWKFSLVPVGGYV
KMFGDALDREMSEEEKLCALNEKPLWQRFLIAFAGPAANLLFSLLVFFVLFSTRGVLSPMPVVGNVLAGSTAELVGLEAG
DRIVSIDGNEVAWFEEIRHYIAGGQGEYLTIGFLRSGVLHHVTIGPEEWSSGARKLGISASSLPMDSQSRRLPVLSAANE
AFLCTYRIVKITLMAVVQLVTGSRSVDELGGPVRIAKHSGDAIRQKEGLRFVGLISANLGVINLLPLPMLDGGFMLQYAL
QGIFRRKTFNPRHCSIVMVVGFILLVSLMVFVTFNDVKSILK

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=254, Percent_Identity=32.6771653543307, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 39521; Mature: 39521

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLARAVSAFQEGSFYVASFLLVLSVVVFIHEYGHYCVAKLCKVKVETFSLGFGPELFG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEECCCCCEEE
ITDGSGTRWKFSLVPVGGYVKMFGDALDREMSEEEKLCALNEKPLWQRFLIAFAGPAANL
EECCCCCEEEEEEEECCHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCCHHHHH
LFSLLVFFVLFSTRGVLSPMPVVGNVLAGSTAELVGLEAGDRIVSIDGNEVAWFEEIRHY
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHEEEECCCCEEEEECCCCCHHHHHHHHH
IAGGQGEYLTIGFLRSGVLHHVTIGPEEWSSGARKLGISASSLPMDSQSRRLPVLSAANE
HCCCCCCEEEEEEHHCCCEEEEEECHHHHCCHHHEECCCCCCCCCCCCCCCCCEEECCCC
AFLCTYRIVKITLMAVVQLVTGSRSVDELGGPVRIAKHSGDAIRQKEGLRFVGLISANLG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCHHHHHCCCEEEEEEECCCC
VINLLPLPMLDGGFMLQYALQGIFRRKTFNPRHCSIVMVVGFILLVSLMVFVTFNDVKSI
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LK
HC
>Mature Secondary Structure
MLSLARAVSAFQEGSFYVASFLLVLSVVVFIHEYGHYCVAKLCKVKVETFSLGFGPELFG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEECCCCCEEE
ITDGSGTRWKFSLVPVGGYVKMFGDALDREMSEEEKLCALNEKPLWQRFLIAFAGPAANL
EECCCCCEEEEEEEECCHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCCHHHHH
LFSLLVFFVLFSTRGVLSPMPVVGNVLAGSTAELVGLEAGDRIVSIDGNEVAWFEEIRHY
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHEEEECCCCEEEEECCCCCHHHHHHHHH
IAGGQGEYLTIGFLRSGVLHHVTIGPEEWSSGARKLGISASSLPMDSQSRRLPVLSAANE
HCCCCCCEEEEEEHHCCCEEEEEECHHHHCCHHHEECCCCCCCCCCCCCCCCCEEECCCC
AFLCTYRIVKITLMAVVQLVTGSRSVDELGGPVRIAKHSGDAIRQKEGLRFVGLISANLG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCHHHHHCCCEEEEEEECCCC
VINLLPLPMLDGGFMLQYALQGIFRRKTFNPRHCSIVMVVGFILLVSLMVFVTFNDVKSI
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LK
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]