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The map label for this gene is ywlC [H]

Identifier: 88196020

GI number: 88196020

Start: 2178626

End: 2179723

Strand: Reverse

Name: ywlC [H]

Synonym: SAOUHSC_02357

Alternate gene names: 88196020

Gene position: 2179723-2178626 (Counterclockwise)

Preceding gene: 88196021

Following gene: 88196019

Centisome position: 77.26

GC content: 34.97

Gene sequence:

>1098_bases
GTGCATAGCTTTTTGCTTTATATTATGATAAATAAGAAAGGCGTGATTAAGTTGGATACTAAAATTTGGGATGTTAGAGA
ATATAATGAAGATTTACAGCAATATCCTAAAATTAATGAAATAAAAGACATTGTTTTAAACGGTGGTTTAATAGGTTTAC
CAACTGAAACAGTTTATGGACTTGCAGCAAATGCGACAGATGAAGAAGCTGTAGCTAAAATATATGAAGCTAAAGGCCGT
CCATCTGACAATCCGCTTATTGTTCATATACACAGTAAAGGTCAATTAAAAGATTTTACATATACTTTGGATCCACGCGT
AGAAAAGTTAATGCAGGCATTCTGGCCGGGCCCTATTTCGTTTATATTGCCGTTAAAGCTAGGCTATCTATGTCGAAAAG
TTTCTGGAGGTTTATCATCAGTTGCTGTTAGAATGCCAAGCCATTCTGTAGGTAGACAATTATTACAAATCATAAATGAA
CCTCTAGCTGCTCCAAGTGCTAATTTAAGTGGTAGACCTTCACCAACAACTTTCAATCATGTATATCAAGATTTGAATGG
CCGTATCGATGGTATTGTTCAAGCTGAACAAAGTGAAGAAGGATTAGAAAGTACGGTTTTAGATTGCACATCTTTTCCTT
ATAAAATTGCAAGACCTGGTTCTATAACAGCAGCAATGATTACAGAAATACTTCCGAATAGTATCGCCCATGCTGATTAT
AATGATACTGAACAGCCAATTGCACCAGGTATGAAGTATAAGCATTACTCACCCAATACACCACTTACAATTATTACAGA
TATTGAGAGCAAAATTGGAAATGACGGTAAAGATTGGTCTTCTATAGCTTTTATTGTGCCGAGTAATAAGGTGGCGTTTA
TACCAAGTGAAGCGCAATTCATTCAATTATGTCAGGATGACAATGATGTTAAACAAGCAAGTCATAATCTTTATGATGTG
TTACATTCACTTGATGAAAATGAAAATATTTCAGCGGCGTATATATACGGCTTTGAGCTGAATGATAATACAGAAGCAAT
TATGAATCGCATGTTAAAAGCTGCAGGTAATCACATTATTAAAGGATGTGAACTATGA

Upstream 100 bases:

>100_bases
CTGACAAAAAAATCGACATTATTAAAGATATAAATGGCCACGATCGAATCGTCTCATTTAAATGGTAATTAGAAGTTATG
CCTTTGCTATGATTAGTTAA

Downstream 100 bases:

>100_bases
AGATTTTATTCGTTTGTACAGGTAACACATGTCGTAGCCCATTAGCGGAAAGTATTGCAAAAGAGGTTATGCCAAATCAT
CAATTTGAATCAAGAGGTAT

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGR
PSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINE
PLAAPSANLSGRPSPTTFNHVYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADY
NDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDV
LHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

Sequences:

>Translated_365_residues
MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGR
PSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINE
PLAAPSANLSGRPSPTTFNHVYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADY
NDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDV
LHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL
>Mature_365_residues
MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGR
PSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINE
PLAAPSANLSGRPSPTTFNHVYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADY
NDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDV
LHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=207, Percent_Identity=32.3671497584541, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI2367210, Length=156, Percent_Identity=34.6153846153846, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537239, Length=183, Percent_Identity=30.6010928961749, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=378, Percent_Identity=31.2169312169312, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI78707274, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 40446; Mature: 40446

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYG
CCCEEEEEEECCCCEEEECCEEEHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCHHHHE
LAANATDEEAVAKIYEAKGRPSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPIS
EECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHCCCCHH
FILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNH
HHHHHHHHHHHHHHCCCHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
VYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADY
HHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
NDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQF
CCCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCEEEEEEECCEEEEECCHHHH
IQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHII
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCHHH
KGCEL
CCCCC
>Mature Secondary Structure
MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYG
CCCEEEEEEECCCCEEEECCEEEHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCHHHHE
LAANATDEEAVAKIYEAKGRPSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPIS
EECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHCCCCHH
FILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNH
HHHHHHHHHHHHHHCCCHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
VYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADY
HHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
NDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQF
CCCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCEEEEEEECCEEEEECCHHHH
IQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHII
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCHHH
KGCEL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]