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The map label for this gene is ltaE [H]

Identifier: 87201279

GI number: 87201279

Start: 3486981

End: 3487997

Strand: Direct

Name: ltaE [H]

Synonym: Saro_3267

Alternate gene names: 87201279

Gene position: 3486981-3487997 (Clockwise)

Preceding gene: 87201268

Following gene: 87201280

Centisome position: 97.91

GC content: 67.35

Gene sequence:

>1017_bases
ATGAAATTCTTTTCCGACAACGCCGCCGCCGTCCATCCCCGCGTGTGGGAGGCCATGCATGCCGCCGACCGTGCCGATTC
AGGCTATGATGGCGATGCGCTTTCACGGCGGCTGGACGATGCGTTCTCCGACCTTTTCGGCACCGAATGCGCCGCATTGT
GGGTGGCGACCGGCACGGCAGCCAACTGCCTTGCCCTGGCGGCGATGGTGCCACCGCACGGCGGCGTGGTCTGTCACCGC
GAGGCCCATGTAGAAATGGACGAAGGCGGCGCTCCAGGGTTCTTCACGCACGGCGCAAAGCTGATGCTGGCCGATGGCGA
AGGCGCGAAGCTGACGCCGCAGGCAATCGAACGCGTGATCGACCCGATCCGTAACGACGTCCACCAGGTGCAGCCGCATG
CGATCTCGATCACGCAGGCGACCGAGTATGGCCGGGTCTACAGCCCCAAGGAAGTCGCCCGGATCGGATCGGTGGCGCAG
GGGCGCGGGCTGGGCCTGCACATGGATGGCGCGCGCTTTGCCAACGCGGTGGCCCACCTTGGTTGCCATCCCGCGGAAGT
AACTGCGCAGGCCGGAGTCGACGTGCTGAGCTTCGGGTGCGTCAAGAATGGGGGCATGAACGCCGAGGCGCTGGTCTTCT
TCGACATGGATCTGGCCGACGTGGTGCGATACCGGCGCAAACGGGCCGGGCACCTGCAGTCGAAAGGCCGTTACCTTGCC
GCCCAGGTGCTTGCGATGATCGAGGGCGACCTGTGGCTGGACAATGCCCGCGCCGCCAACGCCGCCGCGCGCGAGATCGC
CGACGCCTGCGGGACGCGGGTGTTCCATCCGGTCGAGGCGAACGAGATCTTCGTGGTGCTTTCGCCCGCCGAACAGGCGA
CCCTGCGCGCGCAGGGCTTCGACTTCTATGACTGGACCGCCCCCGAAGGCGCGCCGGGCGCGGCGCGGCTGGTGACGGCG
TGGAACAGCGATCCGGCGGAAGTTTCCGCCCTCGCCCGGGCGATAGCGGCCTTATGA

Upstream 100 bases:

>100_bases
CCTGGTCGAGGTGGGTGATCGTGATGTCCGGCATGCGTTTTCTCCTTGCCCGAATGTCGTTGCTTGACCGCAAACGTGCG
CGCCGACATTGCGGTTTCCA

Downstream 100 bases:

>100_bases
CCGCAGCCGAAGCCCCGGGACAGGCGCGGTTCTGGCAGCCCAGCGTGGCAGGGCCGTTCATGCTCGTCGCGCTGATCTGG
GGTTCGACCTGGCTGGTGAT

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKFFSDNAAAVHPRVWEAMHAADRADSGYDGDALSRRLDDAFSDLFGTECAALWVATGTAANCLALAAMVPPHGGVVCHR
EAHVEMDEGGAPGFFTHGAKLMLADGEGAKLTPQAIERVIDPIRNDVHQVQPHAISITQATEYGRVYSPKEVARIGSVAQ
GRGLGLHMDGARFANAVAHLGCHPAEVTAQAGVDVLSFGCVKNGGMNAEALVFFDMDLADVVRYRRKRAGHLQSKGRYLA
AQVLAMIEGDLWLDNARAANAAAREIADACGTRVFHPVEANEIFVVLSPAEQATLRAQGFDFYDWTAPEGAPGAARLVTA
WNSDPAEVSALARAIAAL

Sequences:

>Translated_338_residues
MKFFSDNAAAVHPRVWEAMHAADRADSGYDGDALSRRLDDAFSDLFGTECAALWVATGTAANCLALAAMVPPHGGVVCHR
EAHVEMDEGGAPGFFTHGAKLMLADGEGAKLTPQAIERVIDPIRNDVHQVQPHAISITQATEYGRVYSPKEVARIGSVAQ
GRGLGLHMDGARFANAVAHLGCHPAEVTAQAGVDVLSFGCVKNGGMNAEALVFFDMDLADVVRYRRKRAGHLQSKGRYLA
AQVLAMIEGDLWLDNARAANAAAREIADACGTRVFHPVEANEIFVVLSPAEQATLRAQGFDFYDWTAPEGAPGAARLVTA
WNSDPAEVSALARAIAAL
>Mature_338_residues
MKFFSDNAAAVHPRVWEAMHAADRADSGYDGDALSRRLDDAFSDLFGTECAALWVATGTAANCLALAAMVPPHGGVVCHR
EAHVEMDEGGAPGFFTHGAKLMLADGEGAKLTPQAIERVIDPIRNDVHQVQPHAISITQATEYGRVYSPKEVARIGSVAQ
GRGLGLHMDGARFANAVAHLGCHPAEVTAQAGVDVLSFGCVKNGGMNAEALVFFDMDLADVVRYRRKRAGHLQSKGRYLA
AQVLAMIEGDLWLDNARAANAAAREIADACGTRVFHPVEANEIFVVLSPAEQATLRAQGFDFYDWTAPEGAPGAARLVTA
WNSDPAEVSALARAIAAL

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=243, Percent_Identity=26.3374485596708, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320789, Length=292, Percent_Identity=26.3698630136986, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 35913; Mature: 35913

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFSDNAAAVHPRVWEAMHAADRADSGYDGDALSRRLDDAFSDLFGTECAALWVATGTA
CCEECCCCCEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCH
ANCLALAAMVPPHGGVVCHREAHVEMDEGGAPGFFTHGAKLMLADGEGAKLTPQAIERVI
HHHHHHHHHCCCCCCEEEEECCCEEECCCCCCCEEECCCEEEEECCCCCEECHHHHHHHH
DPIRNDVHQVQPHAISITQATEYGRVYSPKEVARIGSVAQGRGLGLHMDGARFANAVAHL
HHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHCCHHCCCCCEEEECCHHHHHHHHHH
GCHPAEVTAQAGVDVLSFGCVKNGGMNAEALVFFDMDLADVVRYRRKRAGHLQSKGRYLA
CCCCHHHHHHCCCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHCCHHHH
AQVLAMIEGDLWLDNARAANAAAREIADACGTRVFHPVEANEIFVVLSPAEQATLRAQGF
HHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCCHHHHHHCCC
DFYDWTAPEGAPGAARLVTAWNSDPAEVSALARAIAAL
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFFSDNAAAVHPRVWEAMHAADRADSGYDGDALSRRLDDAFSDLFGTECAALWVATGTA
CCEECCCCCEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCH
ANCLALAAMVPPHGGVVCHREAHVEMDEGGAPGFFTHGAKLMLADGEGAKLTPQAIERVI
HHHHHHHHHCCCCCCEEEEECCCEEECCCCCCCEEECCCEEEEECCCCCEECHHHHHHHH
DPIRNDVHQVQPHAISITQATEYGRVYSPKEVARIGSVAQGRGLGLHMDGARFANAVAHL
HHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHCCHHCCCCCEEEECCHHHHHHHHHH
GCHPAEVTAQAGVDVLSFGCVKNGGMNAEALVFFDMDLADVVRYRRKRAGHLQSKGRYLA
CCCCHHHHHHCCCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHCCHHHH
AQVLAMIEGDLWLDNARAANAAAREIADACGTRVFHPVEANEIFVVLSPAEQATLRAQGF
HHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCCHHHHHHCCC
DFYDWTAPEGAPGAARLVTAWNSDPAEVSALARAIAAL
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]