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The map label for this gene is recQ [H]

Identifier: 87201212

GI number: 87201212

Start: 3416729

End: 3418531

Strand: Reverse

Name: recQ [H]

Synonym: Saro_3200

Alternate gene names: 87201212

Gene position: 3418531-3416729 (Counterclockwise)

Preceding gene: 87201213

Following gene: 87201209

Centisome position: 95.98

GC content: 69.05

Gene sequence:

>1803_bases
GTGAGCCTCATCGATCCCGTTTCCGACAGTTCCGCCGTCCTCGACCGCCTCCACGAAGTGTTCGGCTTCACCACCTTCCG
CGGGGTGCAGCGGGACGTGGTGGAGCGCGTGCTGGCGGGGCGCTCGACGCTTGCGGTCATGCCGACGGGCGCGGGCAAGT
CGCTCACCTACCAGCTCCCCGCCGTCATGCTCCCGGGGACTTGCGTGGTCGTATCGCCGCTTATCGCGCTGATGCACGAC
CAACTCCGCAGCGCCACCGCCAACGGCATTCGTGCCGCGACCCTGACCAGCGTCGACCTGGATCGCGGGCAGACCATCGA
CCGCTTCCTGGCGGGCGACCTCGACCTGCTCTACGTCGCTCCCGAACGCGCCAGCCAGCCGCATTTCATGGAAATGCTGA
GCCGGGGGCGCGTGGCGATGTTCGCGATCGACGAGGCCCATTGCGTTTCCGAATGGGGCCATGATTTCCGCCCCGACTAT
CGCCTCCTGCGCCCCCTGATGGACGCCTTCCCGGATGTCCCCCGGCTTGCCCTGACTGCCACGGCCGACCGCCACACCCG
CGCCGATATCCTCGCGCAGCTAGGCATCCCGGAAGAAGGGCTGATCGTCGCCGGGTTCGACCGGCCCAACATCCGTTATG
GCATCGTCCCGCGCGACAATCCGCTGCGGCAGCTGATGACGGTGATTGCCGAGAATCCCGGCCCCGGCATCGTCTATGCC
CCCACCCGCGCGCAGGTGGAGAAGCTGAGCCAGCAGCTGGGTGCGAGCGGCCGGCCCGTGCTGCCCTACCACGCCGGCCT
TGATCCGCAGGTGCGGGCTGCCAATCAGGCCGCCTTCGTCGCGTCGGAAGACATGGTCATGGTCGCCACGGTCGCGTTCG
GCATGGGCATAGACAAGCCCGACGTGCGCTTCGTCGCCCACGCGGCCTGCCCCAAGTCGATCGAGAGCTATTACCAGGAA
ACGGGCCGCGCAGGGCGCGACGGCGACCCGTCTGTCGCGGTCATGCTTTGGGGCGCCGAAGACTTCGTGCGTGCCCGTCA
GAGACTTGCCGAGGTCGAGGAGCACCGCCGCGCGGGCGAGCGCACCCGCATCGATGCGCTGGCATCGCTCGTGGAAACGC
CGCATTGCCGCCGTGCGCTGCTCCTTCGCCACTTCGGCGAAACCCCCCCGCCGTCGTGCGGCAACTGCGACAACTGCCTC
GAAGCGCCCCGGGTGACCGACGCGACCGAGACCGCGCGCAAGCTCCTGTCGGCCGTCTATCGCACCGGCCAGTCATTCGG
CTTCGGATATCTCGAGAAGGTGCTGACCGGCGTTGCCGACGAGCGCGTGATCCAACGTGGTCACGATCAGCTTTCGGTTT
TCGGCATCGTGACCTCCGACGAAGCCCCGTTGCTGCGCCCGCTGGCGAGGGCCTTGCAAGCGCGCGGCGCGCTCGTGGCG
ACCGAGCACGGCGGGCTGGCACTGGGCGGCGAGGCTCGGGCGATCCTCAAGGGCGAGGCGGAAGTGCCGCTGGTGCTGGT
GCCGAAGAAGGAGGGCCGGGGGAGCAGGCGCGGGCGGAGCGGGGCAGGGGCCGCGCTCAACCCCGTGGGCGATCCGCTGT
TCGACGCCCTGCGCGCCTTGCGTCGCGACCTGGCGCGCGAAGCCGGTGTCCCGCCCTATGTCATATTCCACGATTCTGTC
CTGCGCGAATTGGCGGCGTCCCGGCCCGCCACGCTTGCCGACATGGGCCAGATCGGCGGCGTCGGCACCCGCAAGCTCGA
CGCCTACGGCGACCGTTTCCTTGAAGAGATCCGGCAGTGGTAG

Upstream 100 bases:

>100_bases
AGGCGGCTGGAAGATCGTCACAAGCCGCATCAGCAGGCTTCATGTCATTGTCGGATCATCCGGCGTGGAATGACCGCCGC
CTATCTGGCATAGCAGGCGG

Downstream 100 bases:

>100_bases
CCTGAATGGAAGCCCCCTCCCTTGCGCGGGAGGGGGGGATAAATCAAACCGCGGGCTTCGTGCCTTCGTGTCCCCGCGTC
TTGTAGAGCGAGAACACCAC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSLIDPVSDSSAVLDRLHEVFGFTTFRGVQRDVVERVLAGRSTLAVMPTGAGKSLTYQLPAVMLPGTCVVVSPLIALMHD
QLRSATANGIRAATLTSVDLDRGQTIDRFLAGDLDLLYVAPERASQPHFMEMLSRGRVAMFAIDEAHCVSEWGHDFRPDY
RLLRPLMDAFPDVPRLALTATADRHTRADILAQLGIPEEGLIVAGFDRPNIRYGIVPRDNPLRQLMTVIAENPGPGIVYA
PTRAQVEKLSQQLGASGRPVLPYHAGLDPQVRAANQAAFVASEDMVMVATVAFGMGIDKPDVRFVAHAACPKSIESYYQE
TGRAGRDGDPSVAVMLWGAEDFVRARQRLAEVEEHRRAGERTRIDALASLVETPHCRRALLLRHFGETPPPSCGNCDNCL
EAPRVTDATETARKLLSAVYRTGQSFGFGYLEKVLTGVADERVIQRGHDQLSVFGIVTSDEAPLLRPLARALQARGALVA
TEHGGLALGGEARAILKGEAEVPLVLVPKKEGRGSRRGRSGAGAALNPVGDPLFDALRALRRDLAREAGVPPYVIFHDSV
LRELAASRPATLADMGQIGGVGTRKLDAYGDRFLEEIRQW

Sequences:

>Translated_600_residues
MSLIDPVSDSSAVLDRLHEVFGFTTFRGVQRDVVERVLAGRSTLAVMPTGAGKSLTYQLPAVMLPGTCVVVSPLIALMHD
QLRSATANGIRAATLTSVDLDRGQTIDRFLAGDLDLLYVAPERASQPHFMEMLSRGRVAMFAIDEAHCVSEWGHDFRPDY
RLLRPLMDAFPDVPRLALTATADRHTRADILAQLGIPEEGLIVAGFDRPNIRYGIVPRDNPLRQLMTVIAENPGPGIVYA
PTRAQVEKLSQQLGASGRPVLPYHAGLDPQVRAANQAAFVASEDMVMVATVAFGMGIDKPDVRFVAHAACPKSIESYYQE
TGRAGRDGDPSVAVMLWGAEDFVRARQRLAEVEEHRRAGERTRIDALASLVETPHCRRALLLRHFGETPPPSCGNCDNCL
EAPRVTDATETARKLLSAVYRTGQSFGFGYLEKVLTGVADERVIQRGHDQLSVFGIVTSDEAPLLRPLARALQARGALVA
TEHGGLALGGEARAILKGEAEVPLVLVPKKEGRGSRRGRSGAGAALNPVGDPLFDALRALRRDLAREAGVPPYVIFHDSV
LRELAASRPATLADMGQIGGVGTRKLDAYGDRFLEEIRQW
>Mature_599_residues
SLIDPVSDSSAVLDRLHEVFGFTTFRGVQRDVVERVLAGRSTLAVMPTGAGKSLTYQLPAVMLPGTCVVVSPLIALMHDQ
LRSATANGIRAATLTSVDLDRGQTIDRFLAGDLDLLYVAPERASQPHFMEMLSRGRVAMFAIDEAHCVSEWGHDFRPDYR
LLRPLMDAFPDVPRLALTATADRHTRADILAQLGIPEEGLIVAGFDRPNIRYGIVPRDNPLRQLMTVIAENPGPGIVYAP
TRAQVEKLSQQLGASGRPVLPYHAGLDPQVRAANQAAFVASEDMVMVATVAFGMGIDKPDVRFVAHAACPKSIESYYQET
GRAGRDGDPSVAVMLWGAEDFVRARQRLAEVEEHRRAGERTRIDALASLVETPHCRRALLLRHFGETPPPSCGNCDNCLE
APRVTDATETARKLLSAVYRTGQSFGFGYLEKVLTGVADERVIQRGHDQLSVFGIVTSDEAPLLRPLARALQARGALVAT
EHGGLALGGEARAILKGEAEVPLVLVPKKEGRGSRRGRSGAGAALNPVGDPLFDALRALRRDLAREAGVPPYVIFHDSVL
RELAASRPATLADMGQIGGVGTRKLDAYGDRFLEEIRQW

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=637, Percent_Identity=31.0832025117739, Blast_Score=288, Evalue=1e-77,
Organism=Homo sapiens, GI14591902, Length=428, Percent_Identity=35.7476635514019, Blast_Score=261, Evalue=9e-70,
Organism=Homo sapiens, GI14591904, Length=428, Percent_Identity=35.7476635514019, Blast_Score=261, Evalue=9e-70,
Organism=Homo sapiens, GI110735439, Length=495, Percent_Identity=34.5454545454545, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI169218196, Length=493, Percent_Identity=34.2799188640974, Blast_Score=253, Evalue=5e-67,
Organism=Homo sapiens, GI148612816, Length=437, Percent_Identity=35.6979405034325, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI51242943, Length=396, Percent_Identity=36.6161616161616, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI51242947, Length=396, Percent_Identity=36.6161616161616, Blast_Score=220, Evalue=4e-57,
Organism=Homo sapiens, GI284005309, Length=343, Percent_Identity=37.6093294460641, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI148613856, Length=367, Percent_Identity=23.433242506812, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI38201710, Length=367, Percent_Identity=23.433242506812, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4758138, Length=352, Percent_Identity=23.8636363636364, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=589, Percent_Identity=42.2750424448217, Blast_Score=457, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI25145561, Length=657, Percent_Identity=34.3987823439878, Blast_Score=300, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI32564293, Length=671, Percent_Identity=30.7004470938897, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI71987997, Length=437, Percent_Identity=35.9267734553776, Blast_Score=268, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71987993, Length=437, Percent_Identity=35.9267734553776, Blast_Score=268, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI17552866, Length=463, Percent_Identity=33.2613390928726, Blast_Score=212, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6323844, Length=532, Percent_Identity=35.5263157894737, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6324217, Length=358, Percent_Identity=24.0223463687151, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646066, Length=630, Percent_Identity=33.8095238095238, Blast_Score=314, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24664226, Length=448, Percent_Identity=36.1607142857143, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI62472181, Length=452, Percent_Identity=35.6194690265487, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24664230, Length=452, Percent_Identity=35.6194690265487, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI21358123, Length=366, Percent_Identity=36.3387978142077, Blast_Score=179, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 65096; Mature: 64965

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIDPVSDSSAVLDRLHEVFGFTTFRGVQRDVVERVLAGRSTLAVMPTGAGKSLTYQLP
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECC
AVMLPGTCVVVSPLIALMHDQLRSATANGIRAATLTSVDLDRGQTIDRFLAGDLDLLYVA
CEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHCCCEEEEEC
PERASQPHFMEMLSRGRVAMFAIDEAHCVSEWGHDFRPDYRLLRPLMDAFPDVPRLALTA
CCCCCCCHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEE
TADRHTRADILAQLGIPEEGLIVAGFDRPNIRYGIVPRDNPLRQLMTVIAENPGPGIVYA
CCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEEC
PTRAQVEKLSQQLGASGRPVLPYHAGLDPQVRAANQAAFVASEDMVMVATVAFGMGIDKP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCHHEEHHHHHHCCCCCC
DVRFVAHAACPKSIESYYQETGRAGRDGDPSVAVMLWGAEDFVRARQRLAEVEEHRRAGE
CHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCC
RTRIDALASLVETPHCRRALLLRHFGETPPPSCGNCDNCLEAPRVTDATETARKLLSAVY
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
RTGQSFGFGYLEKVLTGVADERVIQRGHDQLSVFGIVTSDEAPLLRPLARALQARGALVA
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEE
TEHGGLALGGEARAILKGEAEVPLVLVPKKEGRGSRRGRSGAGAALNPVGDPLFDALRAL
ECCCCEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RRDLAREAGVPPYVIFHDSVLRELAASRPATLADMGQIGGVGTRKLDAYGDRFLEEIRQW
HHHHHHHCCCCCEEEECHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLIDPVSDSSAVLDRLHEVFGFTTFRGVQRDVVERVLAGRSTLAVMPTGAGKSLTYQLP
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECC
AVMLPGTCVVVSPLIALMHDQLRSATANGIRAATLTSVDLDRGQTIDRFLAGDLDLLYVA
CEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHCCCEEEEEC
PERASQPHFMEMLSRGRVAMFAIDEAHCVSEWGHDFRPDYRLLRPLMDAFPDVPRLALTA
CCCCCCCHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEE
TADRHTRADILAQLGIPEEGLIVAGFDRPNIRYGIVPRDNPLRQLMTVIAENPGPGIVYA
CCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEEC
PTRAQVEKLSQQLGASGRPVLPYHAGLDPQVRAANQAAFVASEDMVMVATVAFGMGIDKP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCHHEEHHHHHHCCCCCC
DVRFVAHAACPKSIESYYQETGRAGRDGDPSVAVMLWGAEDFVRARQRLAEVEEHRRAGE
CHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCC
RTRIDALASLVETPHCRRALLLRHFGETPPPSCGNCDNCLEAPRVTDATETARKLLSAVY
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
RTGQSFGFGYLEKVLTGVADERVIQRGHDQLSVFGIVTSDEAPLLRPLARALQARGALVA
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEE
TEHGGLALGGEARAILKGEAEVPLVLVPKKEGRGSRRGRSGAGAALNPVGDPLFDALRAL
ECCCCEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RRDLAREAGVPPYVIFHDSVLRELAASRPATLADMGQIGGVGTRKLDAYGDRFLEEIRQW
HHHHHHHCCCCCEEEECHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]