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The map label for this gene is fkpA [H]

Identifier: 87200847

GI number: 87200847

Start: 3061771

End: 3062334

Strand: Reverse

Name: fkpA [H]

Synonym: Saro_2834

Alternate gene names: 87200847

Gene position: 3062334-3061771 (Counterclockwise)

Preceding gene: 87200848

Following gene: 87200846

Centisome position: 85.98

GC content: 65.96

Gene sequence:

>564_bases
ATGTCGGAAATCACCCGCGTTCCGCTCCAGCCCATCGCCAAGGGCTCCATCGGCAAGATCTGGCTCGGCGTGATCGTCGC
CGTGCTCATCGGCTCGGGCGTTGCCTATGGCACCCGCTACAAGGGCGTCGTGGTTGAAACGGTGAAGGCCGGCGCTGGCG
CCTCGCCGACGAAGAGCGACGTCGCGCTCATCAACTATGTCGGCCGCCTCGCCAACGGCAAGGAATTCGACCGCGGAGAG
CGTGCGGTCCTGCCGCTCGAAACCGTGATCCCGGGTTTCACCGAAGGCCTCGCCAAGATGCAGAAGGGCGGCAAGTACGT
CCTCGAGATCCCGGCCGAAAAGGCCTACGGCGCCGAGGAAAAGCGCAACCCGCAGACCGGAGAGGTGGTCATCCCCGCCA
ACTCCGACCTCGTGTTCGAGATCGAACTGATCGACTTCAAGAGCGCCGCCGAGCTTGAGCAGCAGCGCATGATGCTCGAA
CAGATGCAGAAGATGCAGGGCGGCGCCGGCGCGGCTCCCGGCGGGGCGCCCATGCCGATGCCGCAGGGCGCTCCGCAACC
CTGA

Upstream 100 bases:

>100_bases
TCCGGCGCCCTTTTTCGTGCGTCGGTGTCCTAGTTGAGTACGTTCAGGCCATTCGAATCATCCGGTGCGATTCGCCCGAA
TCGCGCTTCAGGGGGAAAGC

Downstream 100 bases:

>100_bases
CAGGCGCCGGGCGCCCTTCGGGGCGGCCTCGGCTTGAAGCACGCCGCGCGCTCTGGTAGCGCGCGGCGTTCCTTTTTCCC
GCTTTCGCTTCTCCTGGGAG

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSEITRVPLQPIAKGSIGKIWLGVIVAVLIGSGVAYGTRYKGVVVETVKAGAGASPTKSDVALINYVGRLANGKEFDRGE
RAVLPLETVIPGFTEGLAKMQKGGKYVLEIPAEKAYGAEEKRNPQTGEVVIPANSDLVFEIELIDFKSAAELEQQRMMLE
QMQKMQGGAGAAPGGAPMPMPQGAPQP

Sequences:

>Translated_187_residues
MSEITRVPLQPIAKGSIGKIWLGVIVAVLIGSGVAYGTRYKGVVVETVKAGAGASPTKSDVALINYVGRLANGKEFDRGE
RAVLPLETVIPGFTEGLAKMQKGGKYVLEIPAEKAYGAEEKRNPQTGEVVIPANSDLVFEIELIDFKSAAELEQQRMMLE
QMQKMQGGAGAAPGGAPMPMPQGAPQP
>Mature_186_residues
SEITRVPLQPIAKGSIGKIWLGVIVAVLIGSGVAYGTRYKGVVVETVKAGAGASPTKSDVALINYVGRLANGKEFDRGER
AVLPLETVIPGFTEGLAKMQKGGKYVLEIPAEKAYGAEEKRNPQTGEVVIPANSDLVFEIELIDFKSAAELEQQRMMLEQ
MQKMQGGAGAAPGGAPMPMPQGAPQP

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789745, Length=116, Percent_Identity=47.4137931034483, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI87082390, Length=110, Percent_Identity=38.1818181818182, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19735; Mature: 19604

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEITRVPLQPIAKGSIGKIWLGVIVAVLIGSGVAYGTRYKGVVVETVKAGAGASPTKSD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
VALINYVGRLANGKEFDRGERAVLPLETVIPGFTEGLAKMQKGGKYVLEIPAEKAYGAEE
HHHHHHHHHHCCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHCCCEEEEECCHHHCCCCH
KRNPQTGEVVIPANSDLVFEIELIDFKSAAELEQQRMMLEQMQKMQGGAGAAPGGAPMPM
HCCCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PQGAPQP
CCCCCCC
>Mature Secondary Structure 
SEITRVPLQPIAKGSIGKIWLGVIVAVLIGSGVAYGTRYKGVVVETVKAGAGASPTKSD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
VALINYVGRLANGKEFDRGERAVLPLETVIPGFTEGLAKMQKGGKYVLEIPAEKAYGAEE
HHHHHHHHHHCCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHCCCEEEEECCHHHCCCCH
KRNPQTGEVVIPANSDLVFEIELIDFKSAAELEQQRMMLEQMQKMQGGAGAAPGGAPMPM
HCCCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PQGAPQP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]