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The map label for this gene is ybdR [H]

Identifier: 87200525

GI number: 87200525

Start: 2716714

End: 2717754

Strand: Direct

Name: ybdR [H]

Synonym: Saro_2512

Alternate gene names: 87200525

Gene position: 2716714-2717754 (Clockwise)

Preceding gene: 87200524

Following gene: 87200527

Centisome position: 76.28

GC content: 67.53

Gene sequence:

>1041_bases
ATGAAGGCCCTGCGCTACTACGGTGCCCGCGACATCCGCCATGAATCGATGGATGATCCGACGCCGCAATCGGACCGCGA
CGCAATCGTGAAGGTCGATGCCTGCTCGATCTGCGGCTCCGACCTTCACATCTACCACGGCCACGGCTTTTCCGAGGATA
TCGGCTTCTGCGTGGGCCATGAAGCGGTGGGCGAAGTGGTCGAGGTCGGGCGCGGCGTCCACCGGCTCAAGGTCGGGCAA
AAGGTGATGATCCCCGCCGCGGTCGGCTGCGGGGCCTGCCGCTCGTGCCTCGCAGGGGTGGTCAACACCTGCGAAAACAA
TGGCTCGGGCTGCTACGGCCTGTCCGCGAAGCTACAGGGATCGCAGGCAGAGGCGGTGCGCGTTCCCGCTGCGGATGCCA
ATGCGGTCGCCATTCCCGAAGGCGTCAGCACCGAACAGGCGCTGATGATGACCGACGCGCTCGCCACGGCATGGTTCGGT
GCACGCCAGGCCGATATCCGCCCCGGCAGTTCGGTCGGCATCATCGGCCTCGGGCCGATCGGCCTCATGGCGGCGGAGAG
CGCATTCGTGATGGGCGCACATGTTGTCTATGCGATCGATCCCGTGCCGGAACGCCGCGCCATCGCGGAAAGCCTCGGGG
CCATTGCCTTGCATCCGGACGAGGCTTCCGCGCGGATCAAGGAGGACACGCACGGCAGGCGCCTCGATTGCGTGGTGGAA
GTCGTCGGATCGGATGCCACCGTCGACATGGCCCTGCGGCTCGTGCGCGTGCGCGGCACGGTCTCGGTGATCGGCGTCCA
GCAATCGCGCCGCTTTCCCTTCCCGCTCGAGCGGGCCTTCGCCGGCGGACTCACCTTCCGCGTGGGCACCTGCTCGGTCC
CGGAGGAACTGCCAGCTCTGTTCCCGCTTGTCGCTTCGGGCCGCCTGCGCCCCGAACGCTACATCAGCCACCGCCTGCCC
CTGTCGCAGGGCGCCGAAGCCTACCGCATGTTCGAGGCGCGCGAGGCAGGCGCGCTCAAGATGGTGCTTGTGCCGGACTG
A

Upstream 100 bases:

>100_bases
TCCGCCTCACCGATGGGCCGGAGGAAGTGCACATGAGCCAGCTCGGCAAGATCAAGATCGCCGAATACGTCGCCTCCAAC
GCACGCTGAAGGAACATCGC

Downstream 100 bases:

>100_bases
CTGCGCGCCGCGCAGCAAACCACGGACCGATCCTGCGCACCGCCTCCTCGATCAGCGGCGTCGAAACGGCAAAGCTGAAA
CGGATGAAGCGCTTGCCGTT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKALRYYGARDIRHESMDDPTPQSDRDAIVKVDACSICGSDLHIYHGHGFSEDIGFCVGHEAVGEVVEVGRGVHRLKVGQ
KVMIPAAVGCGACRSCLAGVVNTCENNGSGCYGLSAKLQGSQAEAVRVPAADANAVAIPEGVSTEQALMMTDALATAWFG
ARQADIRPGSSVGIIGLGPIGLMAAESAFVMGAHVVYAIDPVPERRAIAESLGAIALHPDEASARIKEDTHGRRLDCVVE
VVGSDATVDMALRLVRVRGTVSVIGVQQSRRFPFPLERAFAGGLTFRVGTCSVPEELPALFPLVASGRLRPERYISHRLP
LSQGAEAYRMFEAREAGALKMVLVPD

Sequences:

>Translated_346_residues
MKALRYYGARDIRHESMDDPTPQSDRDAIVKVDACSICGSDLHIYHGHGFSEDIGFCVGHEAVGEVVEVGRGVHRLKVGQ
KVMIPAAVGCGACRSCLAGVVNTCENNGSGCYGLSAKLQGSQAEAVRVPAADANAVAIPEGVSTEQALMMTDALATAWFG
ARQADIRPGSSVGIIGLGPIGLMAAESAFVMGAHVVYAIDPVPERRAIAESLGAIALHPDEASARIKEDTHGRRLDCVVE
VVGSDATVDMALRLVRVRGTVSVIGVQQSRRFPFPLERAFAGGLTFRVGTCSVPEELPALFPLVASGRLRPERYISHRLP
LSQGAEAYRMFEAREAGALKMVLVPD
>Mature_346_residues
MKALRYYGARDIRHESMDDPTPQSDRDAIVKVDACSICGSDLHIYHGHGFSEDIGFCVGHEAVGEVVEVGRGVHRLKVGQ
KVMIPAAVGCGACRSCLAGVVNTCENNGSGCYGLSAKLQGSQAEAVRVPAADANAVAIPEGVSTEQALMMTDALATAWFG
ARQADIRPGSSVGIIGLGPIGLMAAESAFVMGAHVVYAIDPVPERRAIAESLGAIALHPDEASARIKEDTHGRRLDCVVE
VVGSDATVDMALRLVRVRGTVSVIGVQQSRRFPFPLERAFAGGLTFRVGTCSVPEELPALFPLVASGRLRPERYISHRLP
LSQGAEAYRMFEAREAGALKMVLVPD

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=354, Percent_Identity=24.5762711864407, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4501929, Length=340, Percent_Identity=27.3529411764706, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI71743840, Length=338, Percent_Identity=23.6686390532544, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI262073058, Length=338, Percent_Identity=23.6686390532544, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI34577061, Length=337, Percent_Identity=26.1127596439169, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4501933, Length=350, Percent_Identity=26.5714285714286, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4501939, Length=340, Percent_Identity=24.1176470588235, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI156523966, Length=340, Percent_Identity=24.1176470588235, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI71565154, Length=356, Percent_Identity=21.9101123595506, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786825, Length=388, Percent_Identity=35.8247422680412, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI87082125, Length=346, Percent_Identity=28.0346820809249, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI226510992, Length=334, Percent_Identity=28.7425149700599, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788073, Length=314, Percent_Identity=28.6624203821656, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788075, Length=363, Percent_Identity=26.7217630853994, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790045, Length=336, Percent_Identity=27.3809523809524, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87081918, Length=325, Percent_Identity=28.6153846153846, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787863, Length=327, Percent_Identity=25.9938837920489, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790718, Length=333, Percent_Identity=24.9249249249249, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788407, Length=336, Percent_Identity=25.8928571428571, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786552, Length=353, Percent_Identity=24.929178470255, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=348, Percent_Identity=26.1494252873563, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562878, Length=340, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=257, Percent_Identity=27.2373540856031, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319257, Length=390, Percent_Identity=25.8974358974359, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6319955, Length=351, Percent_Identity=26.2108262108262, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322619, Length=351, Percent_Identity=26.2108262108262, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319258, Length=327, Percent_Identity=28.1345565749235, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319621, Length=277, Percent_Identity=28.5198555956679, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=277, Percent_Identity=27.0758122743682, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=24.6575342465753, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323980, Length=333, Percent_Identity=28.2282282282282, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319949, Length=346, Percent_Identity=27.4566473988439, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=274, Percent_Identity=27.007299270073, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=264, Percent_Identity=26.8939393939394, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737897, Length=348, Percent_Identity=29.3103448275862, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17137530, Length=348, Percent_Identity=28.448275862069, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI221457811, Length=347, Percent_Identity=26.2247838616715, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550770, Length=347, Percent_Identity=26.2247838616715, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45551930, Length=347, Percent_Identity=26.2247838616715, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17737895, Length=344, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36673; Mature: 36673

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALRYYGARDIRHESMDDPTPQSDRDAIVKVDACSICGSDLHIYHGHGFSEDIGFCVGH
CCCCHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCCEEEEECCCCCCCCCEEECH
EAVGEVVEVGRGVHRLKVGQKVMIPAAVGCGACRSCLAGVVNTCENNGSGCYGLSAKLQG
HHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
SQAEAVRVPAADANAVAIPEGVSTEQALMMTDALATAWFGARQADIRPGSSVGIIGLGPI
CCCCEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCH
GLMAAESAFVMGAHVVYAIDPVPERRAIAESLGAIALHPDEASARIKEDTHGRRLDCVVE
HHHHHCCCEEEEEEEEEEECCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEEEEEE
VVGSDATVDMALRLVRVRGTVSVIGVQQSRRFPFPLERAFAGGLTFRVGTCSVPEELPAL
ECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCHHHHHH
FPLVASGRLRPERYISHRLPLSQGAEAYRMFEAREAGALKMVLVPD
HHHHHCCCCCHHHHHHHCCCHHCCHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MKALRYYGARDIRHESMDDPTPQSDRDAIVKVDACSICGSDLHIYHGHGFSEDIGFCVGH
CCCCHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCCEEEEECCCCCCCCCEEECH
EAVGEVVEVGRGVHRLKVGQKVMIPAAVGCGACRSCLAGVVNTCENNGSGCYGLSAKLQG
HHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
SQAEAVRVPAADANAVAIPEGVSTEQALMMTDALATAWFGARQADIRPGSSVGIIGLGPI
CCCCEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCH
GLMAAESAFVMGAHVVYAIDPVPERRAIAESLGAIALHPDEASARIKEDTHGRRLDCVVE
HHHHHCCCEEEEEEEEEEECCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEEEEEE
VVGSDATVDMALRLVRVRGTVSVIGVQQSRRFPFPLERAFAGGLTFRVGTCSVPEELPAL
ECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCHHHHHH
FPLVASGRLRPERYISHRLPLSQGAEAYRMFEAREAGALKMVLVPD
HHHHHCCCCCHHHHHHHCCCHHCCHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]