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The map label for this gene is nuoA [H]

Identifier: 87200317

GI number: 87200317

Start: 2443430

End: 2443816

Strand: Reverse

Name: nuoA [H]

Synonym: Saro_2303

Alternate gene names: 87200317

Gene position: 2443816-2443430 (Counterclockwise)

Preceding gene: 87200318

Following gene: 87200316

Centisome position: 68.62

GC content: 60.72

Gene sequence:

>387_bases
TTGGTCGACCAAGCATCCTATCTCGCGCAATACCTGCCGATCCTGATCTTCCTCGGGATCGCCCTCGCGCTTTCGGCGGC
ATTCGTGTTCCTGCCGATGGGCGTTGCCCGTCTGACGGGGGCCCACAACCCGACGGCCGAAAAGCTGAGCGAGTACGAAT
GCGGCTTCCCCGCGTTCGAAGACCCGCGCAGCCAGTTCGACGTCCGGTTCTACCTCGTCGCGATCCTCTTCATAATCTTC
GATCTCGAAGCCGCGTTCCTGTTTCCGTGGGCGGTTAGCCTGAAGGAAACGGGCTGGGCCGGATGGACGACCATGATGGT
GTTCCTCGGCGAACTGGTGATCGGCTTCATATACGCCTGGAAGAAGGGCGCGCTGGATTGGGAATGA

Upstream 100 bases:

>100_bases
GGTGGGTGGAATCCGCGCTCGTTGCGGTCCACCCCACTTGCGCCGAGGCGGCGTCGGGACTAGGGCGCTGCCAAACCTGC
TAGCAAGGCGAGTCAGCCCT

Downstream 100 bases:

>100_bases
GCAACATGACCGCTTCTCCGCTCGTCACCGCAGATCAGGGTGCGGTTGCCGCGCCTGACCAGGCGTTTTTCGACAGCCTC
AATGCCGAGGTCAACGACAA

Product: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MVDQASYLAQYLPILIFLGIALALSAAFVFLPMGVARLTGAHNPTAEKLSEYECGFPAFEDPRSQFDVRFYLVAILFIIF
DLEAAFLFPWAVSLKETGWAGWTTMMVFLGELVIGFIYAWKKGALDWE

Sequences:

>Translated_128_residues
MVDQASYLAQYLPILIFLGIALALSAAFVFLPMGVARLTGAHNPTAEKLSEYECGFPAFEDPRSQFDVRFYLVAILFIIF
DLEAAFLFPWAVSLKETGWAGWTTMMVFLGELVIGFIYAWKKGALDWE
>Mature_128_residues
MVDQASYLAQYLPILIFLGIALALSAAFVFLPMGVARLTGAHNPTAEKLSEYECGFPAFEDPRSQFDVRFYLVAILFIIF
DLEAAFLFPWAVSLKETGWAGWTTMMVFLGELVIGFIYAWKKGALDWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=131, Percent_Identity=33.587786259542, Blast_Score=74, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14399; Mature: 14399

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDQASYLAQYLPILIFLGIALALSAAFVFLPMGVARLTGAHNPTAEKLSEYECGFPAFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
DPRSQFDVRFYLVAILFIIFDLEAAFLFPWAVSLKETGWAGWTTMMVFLGELVIGFIYAW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KKGALDWE
HCCCCCCC
>Mature Secondary Structure
MVDQASYLAQYLPILIFLGIALALSAAFVFLPMGVARLTGAHNPTAEKLSEYECGFPAFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
DPRSQFDVRFYLVAILFIIFDLEAAFLFPWAVSLKETGWAGWTTMMVFLGELVIGFIYAW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KKGALDWE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA