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The map label for this gene is nuoC

Identifier: 87200315

GI number: 87200315

Start: 2441936

End: 2442865

Strand: Reverse

Name: nuoC

Synonym: Saro_2301

Alternate gene names: 87200315

Gene position: 2442865-2441936 (Counterclockwise)

Preceding gene: 87200316

Following gene: 87200314

Centisome position: 68.59

GC content: 65.59

Gene sequence:

>930_bases
ATGACGGTACTCCACTCCGCTCCGCGCTGGTCCTCGAACGAGGGCGTGCTCGATACGCTGGTTGCTGCGCTTGGCGACAT
GGTCGCCGCCTCTCGCGAGGAGCATGGCGAGATCCTGCTGACGGTGGTGCGTGACCGCGTCGAGGACGCTCTGCGCCTCC
TTCGCGACGATCACGAATACCAGCAGCTCATGGACATCGCTGGCGTCGACTATCCGCAGCGCGCGGAACGCTTCGACGTC
TGCTACTGTCTGCTTTCGGTGACGAAGAACCATCGCGTGATCGTGAAGGTTTCGACCGACGAAGCGACGCCGGTGCCCAC
CGTTACCACGCTCTGGCCCAATGCCGGCTGGTACGAGCGCGAAGTCTACGACATGTTCGGCGTCCTGTTCGCCGGCAATC
CCGACTTGCGCCGCATCCTGACCGACTACGGCTTCCAGGGGCATCCGTTCCGCAAGGACTTCCCGCTGACCGGCTATGTC
GAGCTGCGCTATTCGGAAGAAGACAAGCGGGTGGTCTACGAGCCGGTGCAACTGGCGCAGGACCTTCGCCAGTTCGACTT
CATGAGCCCCTGGGAAGGCGCGGACTACGTGCTGCCGGGCGATGAAAAGGCCGTGCCGCCGCCGCCAGCCCCGGCTCCGG
TCGCGACTGCGCCCGAGACCAAGGGCGATGCCAAGGCCGACGTTCCGAAGACGACCGAACAGCCCGCCGATACCGGTGCT
GGCGAGAAGGCCAACGACGCTGCGGCAAAACCGGTCGCGGAAGCTGCCGCTCCCGCTGCAACCAAGACCGACGAGCCGGC
TGCGCCCGAACCGACCGAGGATCGTCCGGCCCGCAAGCCGCGCGCGAAGAAGGTTGCCGACACCGAAGGTGCGACCGAAC
CGGCTGCAAAGCCCAAGCGGACGCGAAAGAAGAAGGAGGATGGCGAGTGA

Upstream 100 bases:

>100_bases
GGCTGCCCGCCGACTGCCGAGGCGCTGCTCTATGGCGTGATGCAGTTGCAGCGGAAGATCCGCCGCGCCGGCACGCTCGA
GCGCTGAGGGAGGCTGGATA

Downstream 100 bases:

>100_bases
GCGTCTTGTCCCTTCTTTGTCACTCTGAACCCGTTTCAGGGTCCATCTTTCCGCAAGCACTGCTGCCTGTGGCGGGCACT
GCGTCTGCCGCACGATGGAT

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTVLHSAPRWSSNEGVLDTLVAALGDMVAASREEHGEILLTVVRDRVEDALRLLRDDHEYQQLMDIAGVDYPQRAERFDV
CYCLLSVTKNHRVIVKVSTDEATPVPTVTTLWPNAGWYEREVYDMFGVLFAGNPDLRRILTDYGFQGHPFRKDFPLTGYV
ELRYSEEDKRVVYEPVQLAQDLRQFDFMSPWEGADYVLPGDEKAVPPPPAPAPVATAPETKGDAKADVPKTTEQPADTGA
GEKANDAAAKPVAEAAAPAATKTDEPAAPEPTEDRPARKPRAKKVADTEGATEPAAKPKRTRKKKEDGE

Sequences:

>Translated_309_residues
MTVLHSAPRWSSNEGVLDTLVAALGDMVAASREEHGEILLTVVRDRVEDALRLLRDDHEYQQLMDIAGVDYPQRAERFDV
CYCLLSVTKNHRVIVKVSTDEATPVPTVTTLWPNAGWYEREVYDMFGVLFAGNPDLRRILTDYGFQGHPFRKDFPLTGYV
ELRYSEEDKRVVYEPVQLAQDLRQFDFMSPWEGADYVLPGDEKAVPPPPAPAPVATAPETKGDAKADVPKTTEQPADTGA
GEKANDAAAKPVAEAAAPAATKTDEPAAPEPTEDRPARKPRAKKVADTEGATEPAAKPKRTRKKKEDGE
>Mature_308_residues
TVLHSAPRWSSNEGVLDTLVAALGDMVAASREEHGEILLTVVRDRVEDALRLLRDDHEYQQLMDIAGVDYPQRAERFDVC
YCLLSVTKNHRVIVKVSTDEATPVPTVTTLWPNAGWYEREVYDMFGVLFAGNPDLRRILTDYGFQGHPFRKDFPLTGYVE
LRYSEEDKRVVYEPVQLAQDLRQFDFMSPWEGADYVLPGDEKAVPPPPAPAPVATAPETKGDAKADVPKTTEQPADTGAG
EKANDAAAKPVAEAAAPAATKTDEPAAPEPTEDRPARKPRAKKVADTEGATEPAAKPKRTRKKKEDGE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=160, Percent_Identity=55, Blast_Score=188, Evalue=6e-48,
Organism=Escherichia coli, GI145693162, Length=104, Percent_Identity=44.2307692307692, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=145, Percent_Identity=54.4827586206897, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI32563621, Length=158, Percent_Identity=51.8987341772152, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=51.9125683060109, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_NOVAD (Q2G5Y5)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497572.1
- ProteinModelPortal:   Q2G5Y5
- SMR:   Q2G5Y5
- STRING:   Q2G5Y5
- GeneID:   3915646
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2301
- NMPDR:   fig|48935.1.peg.2906
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   YVELRYS
- ProtClustDB:   CLSK843950
- BioCyc:   NARO279238:SARO_2301-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 34080; Mature: 33949

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLHSAPRWSSNEGVLDTLVAALGDMVAASREEHGEILLTVVRDRVEDALRLLRDDHEY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHH
QQLMDIAGVDYPQRAERFDVCYCLLSVTKNHRVIVKVSTDEATPVPTVTTLWPNAGWYER
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCCHHH
EVYDMFGVLFAGNPDLRRILTDYGFQGHPFRKDFPLTGYVELRYSEEDKRVVYEPVQLAQ
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHH
DLRQFDFMSPWEGADYVLPGDEKAVPPPPAPAPVATAPETKGDAKADVPKTTEQPADTGA
HHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEKANDAAAKPVAEAAAPAATKTDEPAAPEPTEDRPARKPRAKKVADTEGATEPAAKPKR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHH
TRKKKEDGE
HHCCCCCCC
>Mature Secondary Structure 
TVLHSAPRWSSNEGVLDTLVAALGDMVAASREEHGEILLTVVRDRVEDALRLLRDDHEY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHH
QQLMDIAGVDYPQRAERFDVCYCLLSVTKNHRVIVKVSTDEATPVPTVTTLWPNAGWYER
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCCHHH
EVYDMFGVLFAGNPDLRRILTDYGFQGHPFRKDFPLTGYVELRYSEEDKRVVYEPVQLAQ
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHH
DLRQFDFMSPWEGADYVLPGDEKAVPPPPAPAPVATAPETKGDAKADVPKTTEQPADTGA
HHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEKANDAAAKPVAEAAAPAATKTDEPAAPEPTEDRPARKPRAKKVADTEGATEPAAKPKR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHH
TRKKKEDGE
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA