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The map label for this gene is divJ [H]

Identifier: 87200050

GI number: 87200050

Start: 2169049

End: 2170425

Strand: Reverse

Name: divJ [H]

Synonym: Saro_2034

Alternate gene names: 87200050

Gene position: 2170425-2169049 (Counterclockwise)

Preceding gene: 87200051

Following gene: 87200046

Centisome position: 60.94

GC content: 68.7

Gene sequence:

>1377_bases
ATGACCGCCGCTGGGCCAATCCGCGCCCGTCTTGACGGCGCCGACTGCCTGGTCGAGGCGGACGAGACGCTTGCGGCCCT
GCAACTGCGGGTCGGCGGTTCCTATCCCGGACCGCTTGCCATTCCCGGGCTGCTTGCGCTGGCCCGGCGGGCCCGCGTCC
AGCAGGTTCCGCTGGATGGCCTCGTCACCGTCGCGGACGAAGCCCAGCCCGTGTCCTTTCGCGCGCGGGTCGACCCGGCG
GATGGGGGCACGCTGATCAGGATTACCGAGTGGCAGCTTTCCGCCGATGCATGGGCCGCCGAGGAACGCGCCACGGACGA
GCTTCTGCTTCGCCAGGTAGCGGAAGCTCACGTCGTTCTCGATGCGGAACAGCGCGTCATTTCGGGTATGACCGAGGCTG
CCGATCTGGAGCAGTTCGGCCAATCCCTGCGGACGGGCTTCGGCCGGTACTGGACCGACCTCGTCGAACTGCCCGGCAAT
ACCTACCGCCAGCCTCTGCACTGGCGTCTCCTCGATGATGCCGAACTCGAGATACCGGGCTCGTCCAGAGTCTGGCGCGC
GCGCCTGATCCCGCTGCGGGCGGGTGGCTTCGAACTCCTGCTGCTGGCGGACACAGTGCTTGCCAGGCCCACGAAAGCGC
AGACGGCGCCCGGTGCCGCCACTTCGCGCGGGACCGACTGGAAGGGCTTGCTTGGCCGAACCCTGGCACCGGCCTTGCGT
CTGCCGATGAACCGCATCGTCGCCAATGCCGAGACGATCCGTTCTCGCCTGGCCGGCCCGCTCGATGCCCAATACGTCGC
ATATGCCGGCGACATTGCCGAGGCCGGTCGCCATCTCCTCGGTCTGGTCGAAGACCTTGCCGATCTGGAAACGGTCGAGG
ACGAGGATTTCGCTCCGGTCCCGGACCACGTGGACCTTGCCGACTGCGCCCGCCGCGCCGCCGGCATACTCGGGGTCCGC
GCCCAGGAGCGGGGCATCGTCATGGTGCCGCCGTCGATCGAGGCGACCGCGCCCGCGATCGGCGAATTCCGCCGCGTCCT
CCAGATTCTCCTCAACCTGATCGGCAACGCGATCCGCTACGCGCCAGAGCATTCGGCCGTCTCGATCGAGACCGGCGTCG
AGGCGGGCGGGACATGGGTGGCGGTGTCGGACGAGGGGCGGGGAATCGCGCTCGAGGAGGCCGACAAGGTCTTCGAGAAG
TTCGAGCGGCTCGGTCGCAGCGGCGATGGCGGCAGCGGTCTCGGCCTCTACATCTCGCGCAAGCTCGCGCGGGCGATGGG
GGGGGAACTCTCGGTCGAGCAGGCCAAAGGCGGCGGCGCGCGTTTCGTTCTCAGCCTGCCTTCGGATGCAGAGGCGCTTT
CGAGCGCCATCGGCTAA

Upstream 100 bases:

>100_bases
ATTCATCCCGATGTTTCGCTTCCGTCCGATGTCGACTCCGTGCACCCCGATCGCGCAGCCGCGCTTCTTTCGGCGTCGCG
GATCGGGGCGAGGGGCTGAC

Downstream 100 bases:

>100_bases
GGTTCAGCGGCGGCTGCGCCAGAGCGCGCCCAGTCCCAGCAGCATGAGCCCGGCGCCGATCAGCGCCCACTGGCCCTGTG
CGAGCATGAAGCTCGATGCG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTAAGPIRARLDGADCLVEADETLAALQLRVGGSYPGPLAIPGLLALARRARVQQVPLDGLVTVADEAQPVSFRARVDPA
DGGTLIRITEWQLSADAWAAEERATDELLLRQVAEAHVVLDAEQRVISGMTEAADLEQFGQSLRTGFGRYWTDLVELPGN
TYRQPLHWRLLDDAELEIPGSSRVWRARLIPLRAGGFELLLLADTVLARPTKAQTAPGAATSRGTDWKGLLGRTLAPALR
LPMNRIVANAETIRSRLAGPLDAQYVAYAGDIAEAGRHLLGLVEDLADLETVEDEDFAPVPDHVDLADCARRAAGILGVR
AQERGIVMVPPSIEATAPAIGEFRRVLQILLNLIGNAIRYAPEHSAVSIETGVEAGGTWVAVSDEGRGIALEEADKVFEK
FERLGRSGDGGSGLGLYISRKLARAMGGELSVEQAKGGGARFVLSLPSDAEALSSAIG

Sequences:

>Translated_458_residues
MTAAGPIRARLDGADCLVEADETLAALQLRVGGSYPGPLAIPGLLALARRARVQQVPLDGLVTVADEAQPVSFRARVDPA
DGGTLIRITEWQLSADAWAAEERATDELLLRQVAEAHVVLDAEQRVISGMTEAADLEQFGQSLRTGFGRYWTDLVELPGN
TYRQPLHWRLLDDAELEIPGSSRVWRARLIPLRAGGFELLLLADTVLARPTKAQTAPGAATSRGTDWKGLLGRTLAPALR
LPMNRIVANAETIRSRLAGPLDAQYVAYAGDIAEAGRHLLGLVEDLADLETVEDEDFAPVPDHVDLADCARRAAGILGVR
AQERGIVMVPPSIEATAPAIGEFRRVLQILLNLIGNAIRYAPEHSAVSIETGVEAGGTWVAVSDEGRGIALEEADKVFEK
FERLGRSGDGGSGLGLYISRKLARAMGGELSVEQAKGGGARFVLSLPSDAEALSSAIG
>Mature_457_residues
TAAGPIRARLDGADCLVEADETLAALQLRVGGSYPGPLAIPGLLALARRARVQQVPLDGLVTVADEAQPVSFRARVDPAD
GGTLIRITEWQLSADAWAAEERATDELLLRQVAEAHVVLDAEQRVISGMTEAADLEQFGQSLRTGFGRYWTDLVELPGNT
YRQPLHWRLLDDAELEIPGSSRVWRARLIPLRAGGFELLLLADTVLARPTKAQTAPGAATSRGTDWKGLLGRTLAPALRL
PMNRIVANAETIRSRLAGPLDAQYVAYAGDIAEAGRHLLGLVEDLADLETVEDEDFAPVPDHVDLADCARRAAGILGVRA
QERGIVMVPPSIEATAPAIGEFRRVLQILLNLIGNAIRYAPEHSAVSIETGVEAGGTWVAVSDEGRGIALEEADKVFEKF
ERLGRSGDGGSGLGLYISRKLARAMGGELSVEQAKGGGARFVLSLPSDAEALSSAIG

Specific function: Kinase required for the regulation of cell division and differentiation. Makes part of a signal transduction pathway, activating pleD by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=28.4552845528455, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=27.1966527196653, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=109, Percent_Identity=40.3669724770642, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=189, Percent_Identity=32.8042328042328, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082128, Length=219, Percent_Identity=26.4840182648402, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=26.8, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=29.1866028708134, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790436, Length=105, Percent_Identity=32.3809523809524, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=25.5605381165919, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788393, Length=181, Percent_Identity=29.2817679558011, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=218, Percent_Identity=24.7706422018349, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48784; Mature: 48653

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAGPIRARLDGADCLVEADETLAALQLRVGGSYPGPLAIPGLLALARRARVQQVPLDG
CCCCCCCEEEECCCHHEEECCHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LVTVADEAQPVSFRARVDPADGGTLIRITEWQLSADAWAAEERATDELLLRQVAEAHVVL
EEEECCCCCCCEEEEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEE
DAEQRVISGMTEAADLEQFGQSLRTGFGRYWTDLVELPGNTYRQPLHWRLLDDAELEIPG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECCC
SSRVWRARLIPLRAGGFELLLLADTVLARPTKAQTAPGAATSRGTDWKGLLGRTLAPALR
CCCEEEEEEEEEECCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LPMNRIVANAETIRSRLAGPLDAQYVAYAGDIAEAGRHLLGLVEDLADLETVEDEDFAPV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDHVDLADCARRAAGILGVRAQERGIVMVPPSIEATAPAIGEFRRVLQILLNLIGNAIRY
CCCCCHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
APEHSAVSIETGVEAGGTWVAVSDEGRGIALEEADKVFEKFERLGRSGDGGSGLGLYISR
CCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
KLARAMGGELSVEQAKGGGARFVLSLPSDAEALSSAIG
HHHHHHCCCCEEEECCCCCEEEEEECCCCHHHHHHHCC
>Mature Secondary Structure 
TAAGPIRARLDGADCLVEADETLAALQLRVGGSYPGPLAIPGLLALARRARVQQVPLDG
CCCCCCEEEECCCHHEEECCHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LVTVADEAQPVSFRARVDPADGGTLIRITEWQLSADAWAAEERATDELLLRQVAEAHVVL
EEEECCCCCCCEEEEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEE
DAEQRVISGMTEAADLEQFGQSLRTGFGRYWTDLVELPGNTYRQPLHWRLLDDAELEIPG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECCC
SSRVWRARLIPLRAGGFELLLLADTVLARPTKAQTAPGAATSRGTDWKGLLGRTLAPALR
CCCEEEEEEEEEECCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LPMNRIVANAETIRSRLAGPLDAQYVAYAGDIAEAGRHLLGLVEDLADLETVEDEDFAPV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDHVDLADCARRAAGILGVRAQERGIVMVPPSIEATAPAIGEFRRVLQILLNLIGNAIRY
CCCCCHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
APEHSAVSIETGVEAGGTWVAVSDEGRGIALEEADKVFEKFERLGRSGDGGSGLGLYISR
CCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
KLARAMGGELSVEQAKGGGARFVLSLPSDAEALSSAIG
HHHHHHCCCCEEEECCCCCEEEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1438215; 11259647 [H]