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The map label for this gene is trpD

Identifier: 87200039

GI number: 87200039

Start: 2156671

End: 2157663

Strand: Direct

Name: trpD

Synonym: Saro_2023

Alternate gene names: 87200039

Gene position: 2156671-2157663 (Clockwise)

Preceding gene: 87200038

Following gene: 87200040

Centisome position: 60.55

GC content: 69.49

Gene sequence:

>993_bases
ATGACCCTGCTCCCCGATCCCCAGCACCCGCTAGAGGAAGCCGAGGCCGAAGCCGCCTTTGCCGCGATTCTCGATGGCGC
CGTGGCGGATGAAGCCATCGCCCGGTTTCTCGTGGGCCTGTCCGACCGTGGCGAGAACGCCAGCGAGATCGCCGGCGCCG
CCCGGGCCATGCGCGCCCGGATGATCCCGATCAAGGCGCCCGCAAACGCCATCGACGTCTGCGGCACCGGCGGCGACGGG
CATCACACGCTCAACGTCTCCACCGCCGTCAGCCTCGTCGTCGCCGCCTGCGGCGTGCCCGTCGCCAAGCACGGCAACCG
CGCCGCCAGTTCCAAGGCCGGCGCCGCCGATACCCTCGAAGCCCTGGGCCTCAATCTCGACCGCGCCGCCGAAACCGCCG
AAGAGACGTTGGCCGACCTCGGCATCTGCTTCCTCTTCGCCGCGCGTCATCACCCGTCGATGGGCCGTATCATGCCCATC
CGCAAGGCGCTCGGCCGCCGCACCATCTTCAACCTGATGGGGCCGCTCGCCAATCCCGCCAACGTGCGCCGCCAGCTCGT
CGGCATCGCGCGTCCGGCCTATGTCCCGATCTATGCCGAAGCCATCCTGCGCCTCGGCACCGATCACAGCTTCGTCATTT
CCGGCGATGAGGGGCTCGACGAACTGAGCCTTGCCGGCGGCAACGAACTGGCCGAAGTGCGCGACGGCGAAATCTCCATG
CGCCGCGTAACGCCTGCGGACGCCGGCCTGCCCGAAAGCGCGGTCACCGCGATCCGTGGCGGCGACGCGGCCCATAACGC
CCGCGCCCTGCGCGCCCTCCTCGAAGGCGAGCACGGTCCCTACCGCAACGCCGTGCTCTTCAACGCCGCCGCCGCGCTCA
TCATCGCGGGCGAGGCGCAGGACTGGCACGAAGGCGTCGAGGAAGCAGCCGAAGCCATCGACAAGGGCCTTGCCAACGCC
CTTCTCAACTGCTGGATCGCCGCTCTCGAATAG

Upstream 100 bases:

>100_bases
GCGTCCAGTTCCACCCGGAGTCCATCGCCACCGAACACGGCCACGCGATGATCGCGAACTTCCTCAGGATCTGCGGCATC
AAGACGAACCCGCTCCCGGC

Downstream 100 bases:

>100_bases
TGTCCCCGTCGCCATTCATGTCGAGCGGAGTCGAGGCACACTGGCGCAAATCGGTTCTCGACTTCGCGCGAACCCGGCGG
CAAAGGGGGATCGCAATGAC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTLLPDPQHPLEEAEAEAAFAAILDGAVADEAIARFLVGLSDRGENASEIAGAARAMRARMIPIKAPANAIDVCGTGGDG
HHTLNVSTAVSLVVAACGVPVAKHGNRAASSKAGAADTLEALGLNLDRAAETAEETLADLGICFLFAARHHPSMGRIMPI
RKALGRRTIFNLMGPLANPANVRRQLVGIARPAYVPIYAEAILRLGTDHSFVISGDEGLDELSLAGGNELAEVRDGEISM
RRVTPADAGLPESAVTAIRGGDAAHNARALRALLEGEHGPYRNAVLFNAAAALIIAGEAQDWHEGVEEAAEAIDKGLANA
LLNCWIAALE

Sequences:

>Translated_330_residues
MTLLPDPQHPLEEAEAEAAFAAILDGAVADEAIARFLVGLSDRGENASEIAGAARAMRARMIPIKAPANAIDVCGTGGDG
HHTLNVSTAVSLVVAACGVPVAKHGNRAASSKAGAADTLEALGLNLDRAAETAEETLADLGICFLFAARHHPSMGRIMPI
RKALGRRTIFNLMGPLANPANVRRQLVGIARPAYVPIYAEAILRLGTDHSFVISGDEGLDELSLAGGNELAEVRDGEISM
RRVTPADAGLPESAVTAIRGGDAAHNARALRALLEGEHGPYRNAVLFNAAAALIIAGEAQDWHEGVEEAAEAIDKGLANA
LLNCWIAALE
>Mature_329_residues
TLLPDPQHPLEEAEAEAAFAAILDGAVADEAIARFLVGLSDRGENASEIAGAARAMRARMIPIKAPANAIDVCGTGGDGH
HTLNVSTAVSLVVAACGVPVAKHGNRAASSKAGAADTLEALGLNLDRAAETAEETLADLGICFLFAARHHPSMGRIMPIR
KALGRRTIFNLMGPLANPANVRRQLVGIARPAYVPIYAEAILRLGTDHSFVISGDEGLDELSLAGGNELAEVRDGEISMR
RVTPADAGLPESAVTAIRGGDAAHNARALRALLEGEHGPYRNAVLFNAAAALIIAGEAQDWHEGVEEAAEAIDKGLANAL
LNCWIAALE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=268, Percent_Identity=41.044776119403, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320561, Length=318, Percent_Identity=29.874213836478, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_NOVAD (Q2G6R1)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497296.1
- HSSP:   P50384
- ProteinModelPortal:   Q2G6R1
- SMR:   Q2G6R1
- STRING:   Q2G6R1
- GeneID:   3917344
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2023
- NMPDR:   fig|48935.1.peg.2290
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- PhylomeDB:   Q2G6R1
- ProtClustDB:   PRK00188
- BioCyc:   NARO279238:SARO_2023-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34294; Mature: 34163

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLPDPQHPLEEAEAEAAFAAILDGAVADEAIARFLVGLSDRGENASEIAGAARAMRAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MIPIKAPANAIDVCGTGGDGHHTLNVSTAVSLVVAACGVPVAKHGNRAASSKAGAADTLE
CCEECCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCHHCCCCCCHHHHH
ALGLNLDRAAETAEETLADLGICFLFAARHHPSMGRIMPIRKALGRRTIFNLMGPLANPA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
NVRRQLVGIARPAYVPIYAEAILRLGTDHSFVISGDEGLDELSLAGGNELAEVRDGEISM
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCHHHHCCCCEEE
RRVTPADAGLPESAVTAIRGGDAAHNARALRALLEGEHGPYRNAVLFNAAAALIIAGEAQ
EEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEEEECCCH
DWHEGVEEAAEAIDKGLANALLNCWIAALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLLPDPQHPLEEAEAEAAFAAILDGAVADEAIARFLVGLSDRGENASEIAGAARAMRAR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MIPIKAPANAIDVCGTGGDGHHTLNVSTAVSLVVAACGVPVAKHGNRAASSKAGAADTLE
CCEECCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCHHCCCCCCHHHHH
ALGLNLDRAAETAEETLADLGICFLFAARHHPSMGRIMPIRKALGRRTIFNLMGPLANPA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
NVRRQLVGIARPAYVPIYAEAILRLGTDHSFVISGDEGLDELSLAGGNELAEVRDGEISM
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCHHHHCCCCEEE
RRVTPADAGLPESAVTAIRGGDAAHNARALRALLEGEHGPYRNAVLFNAAAALIIAGEAQ
EEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEEEECCCH
DWHEGVEEAAEAIDKGLANALLNCWIAALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA