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The map label for this gene is divL [H]

Identifier: 87200018

GI number: 87200018

Start: 2134947

End: 2137295

Strand: Reverse

Name: divL [H]

Synonym: Saro_2002

Alternate gene names: 87200018

Gene position: 2137295-2134947 (Counterclockwise)

Preceding gene: 87200019

Following gene: 87200017

Centisome position: 60.01

GC content: 68.71

Gene sequence:

>2349_bases
ATGCCTCTGCTCAACCAGACCGCGCTGGTCCTGATCGGACTGCTGCTTGCCGCGTGGACGGTTGGCGCGGGCTGGCTCGT
ACTCGACGCACGGCGGCGCGCGCGGCGCGGCGAGGCGTTGCAACGGCAGGCGCGCAGGCTTGCGCGGATGGTGGACGAAT
CTCCCGCCCTGCCACTGCTGGTCCGCGCCGACGGGAGGATCGAAGGACCCGCGCGCCTGGCCCTGTGGCTCGGTTTCGAG
GCGATGCCCGGCTATCTTTCAGAACTCGACGCCGGCGACCATGGCCTCGACGAAGTTGAGCTGGCCCGGCTTGGCGATGC
GGTGCGACGGGCGCAGAAGACCGGCACGCCGTTCCGCATGGCGCTTACCCCAAGGGGCGGCTCGCGCAGTCTGTGCGCGC
AGGGTCACCTGGCCGATCCGCAGGTCTCGCCGGGCGGGGCCGCGCTCGTCTGGTTCTTCGACGTTTCCGAAAGCGAGGAG
GAACTGGTCGCGCTGCGGGCCGAGACGCGCAAGGCCAAGTCGGATTTCGCCGGGCTTTCGGGCCTGATCGAGGCCGCGCC
CTTGCCGATGTGGTTCCGCGGCCCTGACTTGCGCCTGCGCCTGGTGAACAGCGCCTATGTCGCTGCCGTGGGCGCCGAGA
GCGCGGACCAGGTGATCGCGCAGGGTATCGAACTGATCGAGCCGGTAGAGGGGCTGTCCGCCGCGCAGGTCGCCCGGCAA
GCCCATTCGCGCAAGGTCTCCATCGAACGGTCCCTGCTGGCGACGATCAAGGGCCAGCGCCGCGCGGTGCGGGTGACCGA
CCTTCCGCTTGGCGACGAGGGGGTGGCCGGTTACGTCGTAGACATCGAGGAAATGGAGGAACTGATCCGCCAGTTCCGCC
GGTTCCGCGAGGCGCAGCGCGAGATGCTGGATACGCTTTCCGCCGGGATCGCGCAGTTCGACGAGAAGCGGAACCTCGTT
TTCGCCAACCAGCCATTCCTGCGCATCTTCTCGGTCCCGCAGGCGTGGGTGGTGGACACGCCGCCGTTCGACCGCGTGCT
GGACCGGATGCGCGACGCGGGCCGCCTGCCTGAAGTGCGCGACTTTCCGGAATGGCGCCGCGAGCGGCAGGGATGGTTCC
TTGCCCGCGAGCCGATCGAGGAGCCCTGGCACCTTTCGGACGGTACGCACCTGCGCGTCGTCGGCCAGCCCATGCCGGAC
GGCGGGTTGCTGATGATCTTCGAGGACCGCACCGAGCAGCTCCAGCTTTCGGCAACTCGCGACACGCTGCTGCGCACGCG
TACGGCCACTTTCGACAACCTGTTCGAATCGCTCGCCGTATTCGCGCCAGACGGCCGGTTGCAGCTCTGGAACCGCCGGT
TTGCGGCTGACTGGGGGCTCGACGAGGAGTTCCTGGCAACGCATCCCCGTGCCGACGTCCTGCTCAGCCGCATTGCCGAC
CAGCTCAAACGGCCCGCGCAAGTTGGCACGGTGGCGCAGGTCATCCAGGGGGCGACGCTGGAGCGCAAGCAGCGCAGTGG
CAGGTTGGCGCTGGCTGACGGGCGGCATCTGGCGCTGGCCGGCGTGCCATTGCCGGATGGAAACGGCCTGCTGACCGTGC
TCGACATCACCGACAGCCAGAAGGCCGAGGCGGCGCTGCGCGAACGGAACGCCGCGCTGGTCGAGGCGGACGCGGTCAAG
ACGCGCTTCATCGCCAACATGAGCTATGAATTCCGGACGCCGCTGACGTCCATCGGCGGCTTTGCGGAACTGCTTCAGAG
CGGCATCGCCGGCGATCTGACCGAGCAGCAGAACGAATACGTCGAGGCGATTCTCACGTCGGTAGAGCGCCTGGGCGAGC
AGATCGAGAACGTGCTGGACCTCTCGCAGAGCGAGGCCGGAACGCTGCCGCTGGCGCAGGAACCGGTGGAGATTTTCCCG
CTCCTGACCGATGTGGTGACCGAACGCACCGAGCGCCTTGCCGGTGCCGGCATCACGCTCGATCTGAGGGGCGACAGGTC
CGCAGGCATGGTAACGGGCGATGCGCGGCGGCTGCGGCGCGCTTTCGGCCAGCTCATCGACAATGCGATTGCGGCAACGC
CCGAGGGCGGGCGCATCCTGGTCGAGGCGTCGCGCAAGAAGGGCGGAGCGCTCCAGGTCGTCGTTTCGGACAACGGGCGC
GGGATGGAGCCGGCCGTGCTGGCGCGGGCGCTCGACGGCCTGAAGGTCAGCGCGGATGGCAAGGCGGTCGAACGGCGGCA
GGGATTGGGGCTTCCGCTGGTCCGCCAACTGGTCGAGGCGCACGGCGGAAACCTGGAGCTGATGTCCGAGCCGGGGCTGG
GCACGAGCGCGATCGTGATGCTGCCGTGA

Upstream 100 bases:

>100_bases
CTCTCTTTTCGTGTACATCGGGCGTCCGTTGTCCCCGCAATGCACGGCAATGTAATTCGCCGCATTGAAATTCCGGGGGG
CACGCCGTAGCGAAAGCGTG

Downstream 100 bases:

>100_bases
TCGTCGACCTGCCGGACCTTGCCTCGTCGGAGGCGCTTGCGCGCAGGATCGCCGCGGCCTTGCGTCCGGGTGACGTGGTC
GCCCTTTCCGGGGGGCTGGG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 781

Protein sequence:

>782_residues
MPLLNQTALVLIGLLLAAWTVGAGWLVLDARRRARRGEALQRQARRLARMVDESPALPLLVRADGRIEGPARLALWLGFE
AMPGYLSELDAGDHGLDEVELARLGDAVRRAQKTGTPFRMALTPRGGSRSLCAQGHLADPQVSPGGAALVWFFDVSESEE
ELVALRAETRKAKSDFAGLSGLIEAAPLPMWFRGPDLRLRLVNSAYVAAVGAESADQVIAQGIELIEPVEGLSAAQVARQ
AHSRKVSIERSLLATIKGQRRAVRVTDLPLGDEGVAGYVVDIEEMEELIRQFRRFREAQREMLDTLSAGIAQFDEKRNLV
FANQPFLRIFSVPQAWVVDTPPFDRVLDRMRDAGRLPEVRDFPEWRRERQGWFLAREPIEEPWHLSDGTHLRVVGQPMPD
GGLLMIFEDRTEQLQLSATRDTLLRTRTATFDNLFESLAVFAPDGRLQLWNRRFAADWGLDEEFLATHPRADVLLSRIAD
QLKRPAQVGTVAQVIQGATLERKQRSGRLALADGRHLALAGVPLPDGNGLLTVLDITDSQKAEAALRERNAALVEADAVK
TRFIANMSYEFRTPLTSIGGFAELLQSGIAGDLTEQQNEYVEAILTSVERLGEQIENVLDLSQSEAGTLPLAQEPVEIFP
LLTDVVTERTERLAGAGITLDLRGDRSAGMVTGDARRLRRAFGQLIDNAIAATPEGGRILVEASRKKGGALQVVVSDNGR
GMEPAVLARALDGLKVSADGKAVERRQGLGLPLVRQLVEAHGGNLELMSEPGLGTSAIVMLP

Sequences:

>Translated_782_residues
MPLLNQTALVLIGLLLAAWTVGAGWLVLDARRRARRGEALQRQARRLARMVDESPALPLLVRADGRIEGPARLALWLGFE
AMPGYLSELDAGDHGLDEVELARLGDAVRRAQKTGTPFRMALTPRGGSRSLCAQGHLADPQVSPGGAALVWFFDVSESEE
ELVALRAETRKAKSDFAGLSGLIEAAPLPMWFRGPDLRLRLVNSAYVAAVGAESADQVIAQGIELIEPVEGLSAAQVARQ
AHSRKVSIERSLLATIKGQRRAVRVTDLPLGDEGVAGYVVDIEEMEELIRQFRRFREAQREMLDTLSAGIAQFDEKRNLV
FANQPFLRIFSVPQAWVVDTPPFDRVLDRMRDAGRLPEVRDFPEWRRERQGWFLAREPIEEPWHLSDGTHLRVVGQPMPD
GGLLMIFEDRTEQLQLSATRDTLLRTRTATFDNLFESLAVFAPDGRLQLWNRRFAADWGLDEEFLATHPRADVLLSRIAD
QLKRPAQVGTVAQVIQGATLERKQRSGRLALADGRHLALAGVPLPDGNGLLTVLDITDSQKAEAALRERNAALVEADAVK
TRFIANMSYEFRTPLTSIGGFAELLQSGIAGDLTEQQNEYVEAILTSVERLGEQIENVLDLSQSEAGTLPLAQEPVEIFP
LLTDVVTERTERLAGAGITLDLRGDRSAGMVTGDARRLRRAFGQLIDNAIAATPEGGRILVEASRKKGGALQVVVSDNGR
GMEPAVLARALDGLKVSADGKAVERRQGLGLPLVRQLVEAHGGNLELMSEPGLGTSAIVMLP
>Mature_781_residues
PLLNQTALVLIGLLLAAWTVGAGWLVLDARRRARRGEALQRQARRLARMVDESPALPLLVRADGRIEGPARLALWLGFEA
MPGYLSELDAGDHGLDEVELARLGDAVRRAQKTGTPFRMALTPRGGSRSLCAQGHLADPQVSPGGAALVWFFDVSESEEE
LVALRAETRKAKSDFAGLSGLIEAAPLPMWFRGPDLRLRLVNSAYVAAVGAESADQVIAQGIELIEPVEGLSAAQVARQA
HSRKVSIERSLLATIKGQRRAVRVTDLPLGDEGVAGYVVDIEEMEELIRQFRRFREAQREMLDTLSAGIAQFDEKRNLVF
ANQPFLRIFSVPQAWVVDTPPFDRVLDRMRDAGRLPEVRDFPEWRRERQGWFLAREPIEEPWHLSDGTHLRVVGQPMPDG
GLLMIFEDRTEQLQLSATRDTLLRTRTATFDNLFESLAVFAPDGRLQLWNRRFAADWGLDEEFLATHPRADVLLSRIADQ
LKRPAQVGTVAQVIQGATLERKQRSGRLALADGRHLALAGVPLPDGNGLLTVLDITDSQKAEAALRERNAALVEADAVKT
RFIANMSYEFRTPLTSIGGFAELLQSGIAGDLTEQQNEYVEAILTSVERLGEQIENVLDLSQSEAGTLPLAQEPVEIFPL
LTDVVTERTERLAGAGITLDLRGDRSAGMVTGDARRLRRAFGQLIDNAIAATPEGGRILVEASRKKGGALQVVVSDNGRG
MEPAVLARALDGLKVSADGKAVERRQGLGLPLVRQLVEAHGGNLELMSEPGLGTSAIVMLP

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=278, Percent_Identity=29.4964028776978, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=33.0612244897959, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=35.1464435146443, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI145693157, Length=263, Percent_Identity=28.8973384030418, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=27.1653543307087, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=29.2682926829268, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=26.978417266187, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=26.6375545851528, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=22.2689075630252, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=26.4840182648402, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=25.9911894273128, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85571; Mature: 85440

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLNQTALVLIGLLLAAWTVGAGWLVLDARRRARRGEALQRQARRLARMVDESPALPLL
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHCCHHHHHHHHHHHHHHCCCCCCEEE
VRADGRIEGPARLALWLGFEAMPGYLSELDAGDHGLDEVELARLGDAVRRAQKTGTPFRM
EECCCCCCCCCEEEEEECCHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
ALTPRGGSRSLCAQGHLADPQVSPGGAALVWFFDVSESEEELVALRAETRKAKSDFAGLS
EEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
GLIEAAPLPMWFRGPDLRLRLVNSAYVAAVGAESADQVIAQGIELIEPVEGLSAAQVARQ
HHHHHCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AHSRKVSIERSLLATIKGQRRAVRVTDLPLGDEGVAGYVVDIEEMEELIRQFRRFREAQR
HHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
EMLDTLSAGIAQFDEKRNLVFANQPFLRIFSVPQAWVVDTPPFDRVLDRMRDAGRLPEVR
HHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCEEEECCCCHHHHHHHHHHCCCCCCCC
DFPEWRRERQGWFLAREPIEEPWHLSDGTHLRVVGQPMPDGGLLMIFEDRTEQLQLSATR
CCHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEHHHH
DTLLRTRTATFDNLFESLAVFAPDGRLQLWNRRFAADWGLDEEFLATHPRADVLLSRIAD
HHHHHHHHHHHHHHHHHHHEECCCCCEEHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHH
QLKRPAQVGTVAQVIQGATLERKQRSGRLALADGRHLALAGVPLPDGNGLLTVLDITDSQ
HHHCCHHHHHHHHHHCCCHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEECCCCH
KAEAALRERNAALVEADAVKTRFIANMSYEFRTPLTSIGGFAELLQSGIAGDLTEQQNEY
HHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VEAILTSVERLGEQIENVLDLSQSEAGTLPLAQEPVEIFPLLTDVVTERTERLAGAGITL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
DLRGDRSAGMVTGDARRLRRAFGQLIDNAIAATPEGGRILVEASRKKGGALQVVVSDNGR
EECCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCC
GMEPAVLARALDGLKVSADGKAVERRQGLGLPLVRQLVEAHGGNLELMSEPGLGTSAIVM
CCCHHHHHHHHCCCEEECCCHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEE
LP
EC
>Mature Secondary Structure 
PLLNQTALVLIGLLLAAWTVGAGWLVLDARRRARRGEALQRQARRLARMVDESPALPLL
CCCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHCCHHHHHHHHHHHHHHCCCCCCEEE
VRADGRIEGPARLALWLGFEAMPGYLSELDAGDHGLDEVELARLGDAVRRAQKTGTPFRM
EECCCCCCCCCEEEEEECCHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
ALTPRGGSRSLCAQGHLADPQVSPGGAALVWFFDVSESEEELVALRAETRKAKSDFAGLS
EEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
GLIEAAPLPMWFRGPDLRLRLVNSAYVAAVGAESADQVIAQGIELIEPVEGLSAAQVARQ
HHHHHCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AHSRKVSIERSLLATIKGQRRAVRVTDLPLGDEGVAGYVVDIEEMEELIRQFRRFREAQR
HHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
EMLDTLSAGIAQFDEKRNLVFANQPFLRIFSVPQAWVVDTPPFDRVLDRMRDAGRLPEVR
HHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCEEEECCCCHHHHHHHHHHCCCCCCCC
DFPEWRRERQGWFLAREPIEEPWHLSDGTHLRVVGQPMPDGGLLMIFEDRTEQLQLSATR
CCHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEHHHH
DTLLRTRTATFDNLFESLAVFAPDGRLQLWNRRFAADWGLDEEFLATHPRADVLLSRIAD
HHHHHHHHHHHHHHHHHHHEECCCCCEEHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHH
QLKRPAQVGTVAQVIQGATLERKQRSGRLALADGRHLALAGVPLPDGNGLLTVLDITDSQ
HHHCCHHHHHHHHHHCCCHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEECCCCH
KAEAALRERNAALVEADAVKTRFIANMSYEFRTPLTSIGGFAELLQSGIAGDLTEQQNEY
HHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VEAILTSVERLGEQIENVLDLSQSEAGTLPLAQEPVEIFPLLTDVVTERTERLAGAGITL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
DLRGDRSAGMVTGDARRLRRAFGQLIDNAIAATPEGGRILVEASRKKGGALQVVVSDNGR
EECCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCC
GMEPAVLARALDGLKVSADGKAVERRQGLGLPLVRQLVEAHGGNLELMSEPGLGTSAIVM
CCCHHHHHHHHCCCEEECCCHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEE
LP
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]