Click here to switch to the map view.

The map label for this gene is glk [H]

Identifier: 87199913

GI number: 87199913

Start: 2009128

End: 2010096

Strand: Direct

Name: glk [H]

Synonym: Saro_1896

Alternate gene names: 87199913

Gene position: 2009128-2010096 (Clockwise)

Preceding gene: 87199912

Following gene: 87199914

Centisome position: 56.41

GC content: 66.15

Gene sequence:

>969_bases
ATGCAGGTAGTTGCCGTCGATATTGGCGGAACCCACGCCCGCTTCGCGATTGCCGAAGTCGCGGAAGGCCGCGTGGTCTC
GCTTGGCGAGGCCGTTACGCTCAAGACGGCGGAGCATGGCTCGTTCCAGCTTGCCTGGGAGGATTTCGAGCGCGTTCGTG
GAGAGCCATTGCCCAAGGCCGCGGCTATTGCCGTCGCCGGGCCTGTCGGCGGCGAGATCATCAAGTTCACGAACAATCCG
TGGATCATCCGCCCGGCGTTGATCCCGGAGAAGCTGGGGGCGGAGCAATATGTCGTCGTCAACGACTTCGCCGCCGTGGC
CCATGCTGTCGCGCAGGCGGACCAGAGCCACTTTCTACACCTGAGCGGCCCGGACGAACCGCTGCCCGCCAGCGGCGTGA
CCAGCGTGGTCGGACCAGGGACAGGGCTCGGCGTGGCGCAGTTGTGGCGTGACGGGAACAACTACCGGGTCCAGCCCACC
GAAGGCGGGCACATCGACTTCGCGCCGCTAGATTCGATCGAGGACGCGATCCTTGCCGGTCTGCGCAAGCGCCACCGCCG
CGTTTCGGCGGAACGCGTCGTGGCCGGGCCGGGCATCGTCGATATCTACGAGGCGCTTGCTCTGATCGAAGGACGACCGT
TTACACCCCGGTCTGACCGCGAGTTGTGGGAACTCGGGACTTCCGGAGCGGACAGCCTTGCCGCCGCTGCAGTAGACAGG
TTCTGCCTCTCGCTCGGCAGCGTGGCAGGCGATCTTGCCCTGGCTCACGGCGCCAACGGCGTCGTCATGGCCGGCGGGCT
TGGCCTGCGGATCAAGGACACGCTGGTTCGGTCTGGCTTCTCGGACAGGTTCAGGGCAAAAGGGCGGTTCGAGGCCCTCA
TGGCGGCCATTCCGGTCAAGCTGATCACGCATCCGCAGCCCGGCCTGTTCGGTGCGGCAGCGGCCTTTGCGCAAGCGCAT
ACGTCGTGA

Upstream 100 bases:

>100_bases
ATTCCGATCCCGCCGAGCGCGGCGGATCGGCGATGCTCGCGGCGGCGGGGCTCTGAAGGATATATCCATCCGGCTGACAG
AGGCCGATCTGGGGGACAGG

Downstream 100 bases:

>100_bases
ACCTCGCGGGTCGGCCCGCCTAGCACTTTAATCGTGCAATTAAATTTTGGTGGATTCGCTCCGCCAAGACGGTATTGCTG
TGCGCGAAGTGCGAAGGCGG

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQVVAVDIGGTHARFAIAEVAEGRVVSLGEAVTLKTAEHGSFQLAWEDFERVRGEPLPKAAAIAVAGPVGGEIIKFTNNP
WIIRPALIPEKLGAEQYVVVNDFAAVAHAVAQADQSHFLHLSGPDEPLPASGVTSVVGPGTGLGVAQLWRDGNNYRVQPT
EGGHIDFAPLDSIEDAILAGLRKRHRRVSAERVVAGPGIVDIYEALALIEGRPFTPRSDRELWELGTSGADSLAAAAVDR
FCLSLGSVAGDLALAHGANGVVMAGGLGLRIKDTLVRSGFSDRFRAKGRFEALMAAIPVKLITHPQPGLFGAAAAFAQAH
TS

Sequences:

>Translated_322_residues
MQVVAVDIGGTHARFAIAEVAEGRVVSLGEAVTLKTAEHGSFQLAWEDFERVRGEPLPKAAAIAVAGPVGGEIIKFTNNP
WIIRPALIPEKLGAEQYVVVNDFAAVAHAVAQADQSHFLHLSGPDEPLPASGVTSVVGPGTGLGVAQLWRDGNNYRVQPT
EGGHIDFAPLDSIEDAILAGLRKRHRRVSAERVVAGPGIVDIYEALALIEGRPFTPRSDRELWELGTSGADSLAAAAVDR
FCLSLGSVAGDLALAHGANGVVMAGGLGLRIKDTLVRSGFSDRFRAKGRFEALMAAIPVKLITHPQPGLFGAAAAFAQAH
TS
>Mature_322_residues
MQVVAVDIGGTHARFAIAEVAEGRVVSLGEAVTLKTAEHGSFQLAWEDFERVRGEPLPKAAAIAVAGPVGGEIIKFTNNP
WIIRPALIPEKLGAEQYVVVNDFAAVAHAVAQADQSHFLHLSGPDEPLPASGVTSVVGPGTGLGVAQLWRDGNNYRVQPT
EGGHIDFAPLDSIEDAILAGLRKRHRRVSAERVVAGPGIVDIYEALALIEGRPFTPRSDRELWELGTSGADSLAAAAVDR
FCLSLGSVAGDLALAHGANGVVMAGGLGLRIKDTLVRSGFSDRFRAKGRFEALMAAIPVKLITHPQPGLFGAAAAFAQAH
TS

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=315, Percent_Identity=34.6031746031746, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33761; Mature: 33761

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVVAVDIGGTHARFAIAEVAEGRVVSLGEAVTLKTAEHGSFQLAWEDFERVRGEPLPKA
CEEEEEECCCCCHHHHHHHHCCCCEEECCCEEEEEECCCCCEEEEHHHHHHHCCCCCCCC
AAIAVAGPVGGEIIKFTNNPWIIRPALIPEKLGAEQYVVVNDFAAVAHAVAQADQSHFLH
EEEEEECCCCCEEEEECCCCEEEECCCCHHHCCCCCEEEEEHHHHHHHHHHHCCCCCEEE
LSGPDEPLPASGVTSVVGPGTGLGVAQLWRDGNNYRVQPTEGGHIDFAPLDSIEDAILAG
ECCCCCCCCCCCCCHHCCCCCCCCHHHHHHCCCCEEEECCCCCEEECCCCCHHHHHHHHH
LRKRHRRVSAERVVAGPGIVDIYEALALIEGRPFTPRSDRELWELGTSGADSLAAAAVDR
HHHHHHHHCHHHEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHH
FCLSLGSVAGDLALAHGANGVVMAGGLGLRIKDTLVRSGFSDRFRAKGRFEALMAAIPVK
HHHHHHHHHHHHHEECCCCCEEEECCCCEEEHHHHHHCCCCHHHHCCCHHHHHHHHHCHH
LITHPQPGLFGAAAAFAQAHTS
EEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQVVAVDIGGTHARFAIAEVAEGRVVSLGEAVTLKTAEHGSFQLAWEDFERVRGEPLPKA
CEEEEEECCCCCHHHHHHHHCCCCEEECCCEEEEEECCCCCEEEEHHHHHHHCCCCCCCC
AAIAVAGPVGGEIIKFTNNPWIIRPALIPEKLGAEQYVVVNDFAAVAHAVAQADQSHFLH
EEEEEECCCCCEEEEECCCCEEEECCCCHHHCCCCCEEEEEHHHHHHHHHHHCCCCCEEE
LSGPDEPLPASGVTSVVGPGTGLGVAQLWRDGNNYRVQPTEGGHIDFAPLDSIEDAILAG
ECCCCCCCCCCCCCHHCCCCCCCCHHHHHHCCCCEEEECCCCCEEECCCCCHHHHHHHHH
LRKRHRRVSAERVVAGPGIVDIYEALALIEGRPFTPRSDRELWELGTSGADSLAAAAVDR
HHHHHHHHCHHHEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHH
FCLSLGSVAGDLALAHGANGVVMAGGLGLRIKDTLVRSGFSDRFRAKGRFEALMAAIPVK
HHHHHHHHHHHHHEECCCCCEEEECCCCEEEHHHHHHCCCCHHHHCCCHHHHHHHHHCHH
LITHPQPGLFGAAAAFAQAHTS
EEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254282 [H]