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The map label for this gene is feaR [H]

Identifier: 87199884

GI number: 87199884

Start: 1968031

End: 1968969

Strand: Direct

Name: feaR [H]

Synonym: Saro_1867

Alternate gene names: 87199884

Gene position: 1968031-1968969 (Clockwise)

Preceding gene: 87199883

Following gene: 87199885

Centisome position: 55.26

GC content: 65.92

Gene sequence:

>939_bases
ATGGGTGCGCTTCTCAAGTTTCATACGCAGGACGTCGCTCCGCAGGACCGGGCGCGCTACTGGAACGAGATTGCCGACCG
GGTCTTCACGGGCACGTTCGTCAACGTTCCGGGCGAGGATTTCAGCGGCCGGATGCTGTCGTGGCGCGTCGGCGAACTCG
ACATGATCCGTACGGATTCGACCCATTCCGGGGTCGGCCGCACCCCCATCGCGCAGGACGACGAAAGGCTGATCCTGCAT
CTGCAATGCCGCGGCACCAGCCAGCACATGCAGAAGCAGGCCGAATGCGCGCTCGAGCCGGGCGACTTCGTACTGGCGAG
CCCGCACATTCCCTATTCGATCAAGCTGACCGGGCACGAGATGCTGGTCGTCGAGTTCCCGCGCGCGCCCCTGGCGGAGC
GGTTTCCCGGCGTGGACGATGCCTTGTTGCAGCGCATGTGCGGTGCGTCGCCCGGCGGACGCGTGTTCCACGACTTCCTG
CTTTCGTTGTGGCAGCAGGGTGAACGGGCCGCCGAAGACCCCGAATGGGAAGTCGGCGTGAACGCGGTGTTCTATGACCT
TGCGGCGATGGCGATGCGCGGGGCGCAGCGCCCGAACGCCGAGGTTGGCGAGGCCGACTTGCGACGCAAGGTGCTGGCAA
TGGTCTCCTCCAGCCTGGAGGACCCCGCGCTGCGCACGGCATCGATCGCCGATGCCTGCAACATCTCGGTTCGCACGGTG
CAGAACGTGTTCGCGGCAATGGGTACGACGCCGACCGCGTACATTCTCGAGCAGCGCCTTCGCCGCGCGGCGGACCGGCT
CGTTGGAAGGCCCGACGCCAGCATCACGGAGATCGCCTTCGAACTGGGCTTCAACGACAGCGCCTACTTCACGCGGTGTT
TCCGCCAGCAGTTCGGCGCGGCGCCGCGCGACTGGCGATTGGGAAGGATGTCATCATGA

Upstream 100 bases:

>100_bases
GGGATGCTGACGCTGGGACTGATCGAATCCGCACCGCGCGTGGTGGCGCGGCGCCTAACCCCGGCCTTGGCAGCCGGGAC
CTGACAACGGGAGAAGAGAC

Downstream 100 bases:

>100_bases
ATCATGGGCTTGCCGCGCAATATGAGGCTTGCGCGGCAGTCCTGATCCGGTTGCGCACCAGTGCAAGCGGAAGGGGCAGG
CAGTCGGTAGACATGCCTGC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MGALLKFHTQDVAPQDRARYWNEIADRVFTGTFVNVPGEDFSGRMLSWRVGELDMIRTDSTHSGVGRTPIAQDDERLILH
LQCRGTSQHMQKQAECALEPGDFVLASPHIPYSIKLTGHEMLVVEFPRAPLAERFPGVDDALLQRMCGASPGGRVFHDFL
LSLWQQGERAAEDPEWEVGVNAVFYDLAAMAMRGAQRPNAEVGEADLRRKVLAMVSSSLEDPALRTASIADACNISVRTV
QNVFAAMGTTPTAYILEQRLRRAADRLVGRPDASITEIAFELGFNDSAYFTRCFRQQFGAAPRDWRLGRMSS

Sequences:

>Translated_312_residues
MGALLKFHTQDVAPQDRARYWNEIADRVFTGTFVNVPGEDFSGRMLSWRVGELDMIRTDSTHSGVGRTPIAQDDERLILH
LQCRGTSQHMQKQAECALEPGDFVLASPHIPYSIKLTGHEMLVVEFPRAPLAERFPGVDDALLQRMCGASPGGRVFHDFL
LSLWQQGERAAEDPEWEVGVNAVFYDLAAMAMRGAQRPNAEVGEADLRRKVLAMVSSSLEDPALRTASIADACNISVRTV
QNVFAAMGTTPTAYILEQRLRRAADRLVGRPDASITEIAFELGFNDSAYFTRCFRQQFGAAPRDWRLGRMSS
>Mature_311_residues
GALLKFHTQDVAPQDRARYWNEIADRVFTGTFVNVPGEDFSGRMLSWRVGELDMIRTDSTHSGVGRTPIAQDDERLILHL
QCRGTSQHMQKQAECALEPGDFVLASPHIPYSIKLTGHEMLVVEFPRAPLAERFPGVDDALLQRMCGASPGGRVFHDFLL
SLWQQGERAAEDPEWEVGVNAVFYDLAAMAMRGAQRPNAEVGEADLRRKVLAMVSSSLEDPALRTASIADACNISVRTVQ
NVFAAMGTTPTAYILEQRLRRAADRLVGRPDASITEIAFELGFNDSAYFTRCFRQQFGAAPRDWRLGRMSS

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=287, Percent_Identity=24.7386759581882, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790339, Length=237, Percent_Identity=27.0042194092827, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34719; Mature: 34588

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALLKFHTQDVAPQDRARYWNEIADRVFTGTFVNVPGEDFSGRMLSWRVGELDMIRTDS
CCCCEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCEEEEECCC
THSGVGRTPIAQDDERLILHLQCRGTSQHMQKQAECALEPGDFVLASPHIPYSIKLTGHE
CCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCE
MLVVEFPRAPLAERFPGVDDALLQRMCGASPGGRVFHDFLLSLWQQGERAAEDPEWEVGV
EEEEECCCCCHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
NAVFYDLAAMAMRGAQRPNAEVGEADLRRKVLAMVSSSLEDPALRTASIADACNISVRTV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHH
QNVFAAMGTTPTAYILEQRLRRAADRLVGRPDASITEIAFELGFNDSAYFTRCFRQQFGA
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
APRDWRLGRMSS
CCCCCCCCCCCC
>Mature Secondary Structure 
GALLKFHTQDVAPQDRARYWNEIADRVFTGTFVNVPGEDFSGRMLSWRVGELDMIRTDS
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCEEEEECCC
THSGVGRTPIAQDDERLILHLQCRGTSQHMQKQAECALEPGDFVLASPHIPYSIKLTGHE
CCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCE
MLVVEFPRAPLAERFPGVDDALLQRMCGASPGGRVFHDFLLSLWQQGERAAEDPEWEVGV
EEEEECCCCCHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
NAVFYDLAAMAMRGAQRPNAEVGEADLRRKVLAMVSSSLEDPALRTASIADACNISVRTV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHH
QNVFAAMGTTPTAYILEQRLRRAADRLVGRPDASITEIAFELGFNDSAYFTRCFRQQFGA
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
APRDWRLGRMSS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]