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The map label for this gene is rnhB

Identifier: 87199856

GI number: 87199856

Start: 1938693

End: 1939283

Strand: Direct

Name: rnhB

Synonym: Saro_1839

Alternate gene names: 87199856

Gene position: 1938693-1939283 (Clockwise)

Preceding gene: 87199854

Following gene: 87199857

Centisome position: 54.43

GC content: 68.36

Gene sequence:

>591_bases
ATGGTCACCATCGGCGTGGACGAGGCTGGTCGTGGGCCCTTGGCGGGGCCGGTAGTTGCTGCGGCGGTGGTGCTGTGCAA
GCCGCGCCCATCAGGGCTCGACGATTCCAAGAAGCTCAGCGCTGCGCGACGGGCGGAGCTTGAAGAGAAGATCAAGCGGC
GCTGCCGGTGGGCCGTGGGCGTCGTGGAACCGGATGAGATCGACCGGCTCAACATCTTCGGCGCGACGATGCTGGCGATG
ACGCTGGCCGTCGGCGCGCTGTGCGAACAGCTTGCCCATGACGAGGACGTGGGCGAAGTGCTGGTCGACGGAAACCTGAC
CCCGCATGGCCGGCGGCCCGAGTGGTGCTGGCCAGCGCGGCCCATCGTGGGCGGGGATGCCCTCGAACCCTGCATTTCGG
CCGCCTCGATCATCGCAAAGGAACATCGCGACCGCCTGATGCGCGAGGCCGCTCTGGCACACCCGCACTACGGGTGGGAG
CGCAATGCAGGGTATGGAACGCCCGAGCATCTGGCGGCCCTGCGCGAACATGGCCCAACGCCGCTCCACCGCCGCAGCTT
CGCGCCGGTCGCGCAGTTGCAGCTTCTCTGA

Upstream 100 bases:

>100_bases
TGCGAGGAGAAGAGCGAGAGGCGATAGCGAGCGCAGGATCGGATTCGTCATGGCTCTCACAATGCTCCCGAATGCCACTT
GTGCCACTTCCTTTTCGTCC

Downstream 100 bases:

>100_bases
TCGTTCGCCCTTGCTTCGCTCTGCACGCAATGCCGAGGGGGCGGGAAATTTTTTGCGGGTGAGTCCGCGGGGGCACACCA
CTAGATGTTGAGTCCGTGCA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MVTIGVDEAGRGPLAGPVVAAAVVLCKPRPSGLDDSKKLSAARRAELEEKIKRRCRWAVGVVEPDEIDRLNIFGATMLAM
TLAVGALCEQLAHDEDVGEVLVDGNLTPHGRRPEWCWPARPIVGGDALEPCISAASIIAKEHRDRLMREAALAHPHYGWE
RNAGYGTPEHLAALREHGPTPLHRRSFAPVAQLQLL

Sequences:

>Translated_196_residues
MVTIGVDEAGRGPLAGPVVAAAVVLCKPRPSGLDDSKKLSAARRAELEEKIKRRCRWAVGVVEPDEIDRLNIFGATMLAM
TLAVGALCEQLAHDEDVGEVLVDGNLTPHGRRPEWCWPARPIVGGDALEPCISAASIIAKEHRDRLMREAALAHPHYGWE
RNAGYGTPEHLAALREHGPTPLHRRSFAPVAQLQLL
>Mature_196_residues
MVTIGVDEAGRGPLAGPVVAAAVVLCKPRPSGLDDSKKLSAARRAELEEKIKRRCRWAVGVVEPDEIDRLNIFGATMLAM
TLAVGALCEQLAHDEDVGEVLVDGNLTPHGRRPEWCWPARPIVGGDALEPCISAASIIAKEHRDRLMREAALAHPHYGWE
RNAGYGTPEHLAALREHGPTPLHRRSFAPVAQLQLL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=188, Percent_Identity=51.063829787234, Blast_Score=150, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_NOVAD (Q2G794)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497113.1
- ProteinModelPortal:   Q2G794
- SMR:   Q2G794
- STRING:   Q2G794
- GeneID:   3918399
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1839
- NMPDR:   fig|48935.1.peg.460
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   NARO279238:SARO_1839-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21289; Mature: 21289

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIGVDEAGRGPLAGPVVAAAVVLCKPRPSGLDDSKKLSAARRAELEEKIKRRCRWAVG
CEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VVEPDEIDRLNIFGATMLAMTLAVGALCEQLAHDEDVGEVLVDGNLTPHGRRPEWCWPAR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCC
PIVGGDALEPCISAASIIAKEHRDRLMREAALAHPHYGWERNAGYGTPEHLAALREHGPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PLHRRSFAPVAQLQLL
CCCCCCCCCHHHHCCC
>Mature Secondary Structure
MVTIGVDEAGRGPLAGPVVAAAVVLCKPRPSGLDDSKKLSAARRAELEEKIKRRCRWAVG
CEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VVEPDEIDRLNIFGATMLAMTLAVGALCEQLAHDEDVGEVLVDGNLTPHGRRPEWCWPAR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCC
PIVGGDALEPCISAASIIAKEHRDRLMREAALAHPHYGWERNAGYGTPEHLAALREHGPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PLHRRSFAPVAQLQLL
CCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA