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The map label for this gene is apr [H]

Identifier: 87199854

GI number: 87199854

Start: 1935151

End: 1937463

Strand: Direct

Name: apr [H]

Synonym: Saro_1837

Alternate gene names: 87199854

Gene position: 1935151-1937463 (Clockwise)

Preceding gene: 87199844

Following gene: 87199856

Centisome position: 54.33

GC content: 70.0

Gene sequence:

>2313_bases
ATGATTGCGTGGAAGTTCGCGGGGCAATCGGCCCTTTTGGTTCTGGCCTTGGCCCTGACAGGCTGCGGTGGAGGCGGCGG
AGTAGCGAGCACGCCGACGCCGACGCCGACGCCCAGCCCGACCCCATCGCCGGCCCCCACGCCAACGCCGACGCCCACGC
CCACGCCCACGCCTACGCCGGTTTCCTACAATACCGCCGAATATCGCAATTCGGACGGCCCCGTGTTCCACGGCGCGATT
ACCGCGTGGGAAGCGGGGGCATCCGGCGCGGGGACGACGATTGCCATCGTGGACAGCGGGATCGATACCGCCAACAGCGA
GTTCGCGGGCCGGATCTCGTCAGCATCGGCGGACGTCGCCGGATCGCGCGGCGTAAGGAACACCGGGGACGATCACGGAA
CGCAGGTCGCGCTCGTCGCGGCGGCAGCGCGCAACGATTACGGAGTGATGGGCATCGCCTGGGGCGCCACAGTACAGATG
CTGCGCGCGGATACACCCGGAACCTGCGCAAGTGCGGATGGGTGCACATTCTCCGACACGAACATCGCCGAAGGAATCGA
CGCAGCGGTTGGAGCGGGCGCCCGGGTGGTCAATCTCTCGCTTGGTGGCGAAGCGGCGGATACAAACCTGCGCGCCGCCG
TCGCCCGCGCCACGTCCGCCGGGCTGATCGTGGTGGTATCAGCCGGCAACGACGGGCAGAGCACCGATCCGGCCATTGAC
CCGAACAACCCCGACCCCTTCGCGGTGTCGCTGCTCCAGGCAGGCGGTGGCAACGTGATCATCGTCGGATCGGTCAGCTC
CGCCGGGCTGGTCTCGGACTTCAGCAACCGTGCAGGCTCGTCGGCATCCTCGTTCCTCATGGCCCAAGGCGAGACGATCT
GCTGCGTGTACGAAGGCAGCCAGATCCGCGTGGTCGACGGTTTCCGCACGGCCGTGAATGGAACAAGCTTCGCCGCGCCC
CAGGTCTCGGGCGCGGTCGCTCTTCTCGCCCAGGCGTTCCCGAACCTCACGGGCGCGCAAATCGTCAGCCTCCTGCTGAG
TACGGCGCGCGAGGGCGGGGCAATCGGCACCGACCCTATCTACGGGCGCGGCATTCTCGATATCGCGCGAGCCTTTTCGC
CGCAGGGTAGCACTGGCCTCGCCGGAACCAGCGTCGCCGTCTCGCTCGACAGCGTTGCGGGCACGACTTCGGGCGCGATG
GGCGATGCGGTTTCGGGGGCCTCGCTCGGCACGGTCATGCTCGACGGCTACGGCAGGGCCTATGCTCTCGATCTCGGACG
GGGGCTCCGTTTCGGTCAGGCGCGTCAGCCCTTGCTGGAGGCGCTGCGGGCCGGGGCGCGGCCAACCGGGTTCGAGGCCG
GCGACGTGTCGCTCGCCTTCTCCGTGGACCGGCGGTTCGGGGCCGTGCCGTTGCGCCTTGCGCCGGGCGAGCGGGAGCAG
GCTCGCGTGCTGGCATCGACGCTGGTGACGCGGATCGGGAACGCGCGCGAACTCGCGCTCGGATGGAACACATCCTCCGA
TGCGCTGGCGGCACGTTTGCAGAAACGGCGCGAGGCGCAGTTCCTCGTCGCCGGTACGGCCAATGGCATGTTCGAGCGTC
CCGAGCTTGGCTTCGCGGCACGGCAGAGGTTCGGCGGCATGGGCGTCACCGTCAGCGGCGGTCGCAGCCTTGTCTGGCGG
CCCGAAGCATTGCGCGACCGTCGCGAGGACAGGCTGGCGCGCCTTGGCGTGGCGTTGGATGGCCACGGGGGCGATGCCCT
CGACTGGCGGCTTGGCCTGGGCCTCATGCGCGAGGAGCGTACCGTGCTGGGCGCACGCTTCGCCGATGCGCTGGGCGGCG
GCGGTGCCACGACCGGCACGATCGAGCCCGGCGTTACCTGGCGGCCGATGCGCGGATGGCACGTGGGCGCAACGGGCAGC
CTGGGCTTCACCCGGGTCGCGGGAACCTCTGTGGCGCCCGGCGGGTCGAGGCTGGTGTCGTCGTCGTGGGCGTTCGACGT
TGCGCGCGATGGCGCCCTGATCGAGGGCGACCGCCTTGGCCTGCGCCTGTCGCAGCCGTTGCGGGTGGAAAGCGGCGGGT
TGGCGCTGAACCTTCCGGTCGCTTGGGACTATGCGACGCAGACTGCCCGTTTTGGCCGCGTCCCTTTATCCCTTGCGCCA
AAGGGGCGCGAGCTTGACGCGGAAGTGGCGTGGTCGGCGCGGCTGTGGGACGGCGCCTTTTCCGCCAGCCTGTTCTGGCG
GCGCGATCCGGGGCACTTCGCCGCCGCGCCCGACGATGCCGGCGGGGCGGTGCGCTGGACGGCGGGGTTCTAG

Upstream 100 bases:

>100_bases
CGGTCCTGCTAAAGCTGTGTCATTCGGCATTTACCGTTTGGGGGTTATCAGCAAGAGACGGTGATGGCCACGGTGCGGTG
GCTTTCGACAGGGAATCGCG

Downstream 100 bases:

>100_bases
GTCGTAAACTCATGGAGGGCGCCATCGAGGTTTGAGGCAGAACGGCCTAGCTCTTTGGGGACAGGTGGCGAAGCCGCGCG
CCTTCGCCGTCTTCCAACAC

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 770; Mature: 770

Protein sequence:

>770_residues
MIAWKFAGQSALLVLALALTGCGGGGGVASTPTPTPTPSPTPSPAPTPTPTPTPTPTPTPVSYNTAEYRNSDGPVFHGAI
TAWEAGASGAGTTIAIVDSGIDTANSEFAGRISSASADVAGSRGVRNTGDDHGTQVALVAAAARNDYGVMGIAWGATVQM
LRADTPGTCASADGCTFSDTNIAEGIDAAVGAGARVVNLSLGGEAADTNLRAAVARATSAGLIVVVSAGNDGQSTDPAID
PNNPDPFAVSLLQAGGGNVIIVGSVSSAGLVSDFSNRAGSSASSFLMAQGETICCVYEGSQIRVVDGFRTAVNGTSFAAP
QVSGAVALLAQAFPNLTGAQIVSLLLSTAREGGAIGTDPIYGRGILDIARAFSPQGSTGLAGTSVAVSLDSVAGTTSGAM
GDAVSGASLGTVMLDGYGRAYALDLGRGLRFGQARQPLLEALRAGARPTGFEAGDVSLAFSVDRRFGAVPLRLAPGEREQ
ARVLASTLVTRIGNARELALGWNTSSDALAARLQKRREAQFLVAGTANGMFERPELGFAARQRFGGMGVTVSGGRSLVWR
PEALRDRREDRLARLGVALDGHGGDALDWRLGLGLMREERTVLGARFADALGGGGATTGTIEPGVTWRPMRGWHVGATGS
LGFTRVAGTSVAPGGSRLVSSSWAFDVARDGALIEGDRLGLRLSQPLRVESGGLALNLPVAWDYATQTARFGRVPLSLAP
KGRELDAEVAWSARLWDGAFSASLFWRRDPGHFAAAPDDAGGAVRWTAGF

Sequences:

>Translated_770_residues
MIAWKFAGQSALLVLALALTGCGGGGGVASTPTPTPTPSPTPSPAPTPTPTPTPTPTPTPVSYNTAEYRNSDGPVFHGAI
TAWEAGASGAGTTIAIVDSGIDTANSEFAGRISSASADVAGSRGVRNTGDDHGTQVALVAAAARNDYGVMGIAWGATVQM
LRADTPGTCASADGCTFSDTNIAEGIDAAVGAGARVVNLSLGGEAADTNLRAAVARATSAGLIVVVSAGNDGQSTDPAID
PNNPDPFAVSLLQAGGGNVIIVGSVSSAGLVSDFSNRAGSSASSFLMAQGETICCVYEGSQIRVVDGFRTAVNGTSFAAP
QVSGAVALLAQAFPNLTGAQIVSLLLSTAREGGAIGTDPIYGRGILDIARAFSPQGSTGLAGTSVAVSLDSVAGTTSGAM
GDAVSGASLGTVMLDGYGRAYALDLGRGLRFGQARQPLLEALRAGARPTGFEAGDVSLAFSVDRRFGAVPLRLAPGEREQ
ARVLASTLVTRIGNARELALGWNTSSDALAARLQKRREAQFLVAGTANGMFERPELGFAARQRFGGMGVTVSGGRSLVWR
PEALRDRREDRLARLGVALDGHGGDALDWRLGLGLMREERTVLGARFADALGGGGATTGTIEPGVTWRPMRGWHVGATGS
LGFTRVAGTSVAPGGSRLVSSSWAFDVARDGALIEGDRLGLRLSQPLRVESGGLALNLPVAWDYATQTARFGRVPLSLAP
KGRELDAEVAWSARLWDGAFSASLFWRRDPGHFAAAPDDAGGAVRWTAGF
>Mature_770_residues
MIAWKFAGQSALLVLALALTGCGGGGGVASTPTPTPTPSPTPSPAPTPTPTPTPTPTPTPVSYNTAEYRNSDGPVFHGAI
TAWEAGASGAGTTIAIVDSGIDTANSEFAGRISSASADVAGSRGVRNTGDDHGTQVALVAAAARNDYGVMGIAWGATVQM
LRADTPGTCASADGCTFSDTNIAEGIDAAVGAGARVVNLSLGGEAADTNLRAAVARATSAGLIVVVSAGNDGQSTDPAID
PNNPDPFAVSLLQAGGGNVIIVGSVSSAGLVSDFSNRAGSSASSFLMAQGETICCVYEGSQIRVVDGFRTAVNGTSFAAP
QVSGAVALLAQAFPNLTGAQIVSLLLSTAREGGAIGTDPIYGRGILDIARAFSPQGSTGLAGTSVAVSLDSVAGTTSGAM
GDAVSGASLGTVMLDGYGRAYALDLGRGLRFGQARQPLLEALRAGARPTGFEAGDVSLAFSVDRRFGAVPLRLAPGEREQ
ARVLASTLVTRIGNARELALGWNTSSDALAARLQKRREAQFLVAGTANGMFERPELGFAARQRFGGMGVTVSGGRSLVWR
PEALRDRREDRLARLGVALDGHGGDALDWRLGLGLMREERTVLGARFADALGGGGATTGTIEPGVTWRPMRGWHVGATGS
LGFTRVAGTSVAPGGSRLVSSSWAFDVARDGALIEGDRLGLRLSQPLRVESGGLALNLPVAWDYATQTARFGRVPLSLAP
KGRELDAEVAWSARLWDGAFSASLFWRRDPGHFAAAPDDAGGAVRWTAGF

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 78377; Mature: 78377

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAWKFAGQSALLVLALALTGCGGGGGVASTPTPTPTPSPTPSPAPTPTPTPTPTPTPTP
CEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VSYNTAEYRNSDGPVFHGAITAWEAGASGAGTTIAIVDSGIDTANSEFAGRISSASADVA
CCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCC
GSRGVRNTGDDHGTQVALVAAAARNDYGVMGIAWGATVQMLRADTPGTCASADGCTFSDT
CCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
NIAEGIDAAVGAGARVVNLSLGGEAADTNLRAAVARATSAGLIVVVSAGNDGQSTDPAID
CHHHCCHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
PNNPDPFAVSLLQAGGGNVIIVGSVSSAGLVSDFSNRAGSSASSFLMAQGETICCVYEGS
CCCCCHHEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCHHEEEECCCEEEEEEECC
QIRVVDGFRTAVNGTSFAAPQVSGAVALLAQAFPNLTGAQIVSLLLSTAREGGAIGTDPI
EEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YGRGILDIARAFSPQGSTGLAGTSVAVSLDSVAGTTSGAMGDAVSGASLGTVMLDGYGRA
CCCHHHHHHHHCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCEEEECCCCCE
YALDLGRGLRFGQARQPLLEALRAGARPTGFEAGDVSLAFSVDRRFGAVPLRLAPGEREQ
EEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCHHH
ARVLASTLVTRIGNARELALGWNTSSDALAARLQKRREAQFLVAGTANGMFERPELGFAA
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHH
RQRFGGMGVTVSGGRSLVWRPEALRDRREDRLARLGVALDGHGGDALDWRLGLGLMREER
HHHCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCEEEECCCCCEEEHHHCCCHHHHHH
TVLGARFADALGGGGATTGTIEPGVTWRPMRGWHVGATGSLGFTRVAGTSVAPGGSRLVS
HHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEECCCCCCCCEEEECCCCCCCCCCCEEC
SSWAFDVARDGALIEGDRLGLRLSQPLRVESGGLALNLPVAWDYATQTARFGRVPLSLAP
CCCEEEECCCCCEEECCCCCEEECCCEEEECCCEEEECCEEECCHHHHHHHCCCCEEECC
KGRELDAEVAWSARLWDGAFSASLFWRRDPGHFAAAPDDAGGAVRWTAGF
CCCCCCCEEEEEEEEECCCCCEEEEEEECCCCEECCCCCCCCEEEEECCC
>Mature Secondary Structure
MIAWKFAGQSALLVLALALTGCGGGGGVASTPTPTPTPSPTPSPAPTPTPTPTPTPTPTP
CEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VSYNTAEYRNSDGPVFHGAITAWEAGASGAGTTIAIVDSGIDTANSEFAGRISSASADVA
CCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCC
GSRGVRNTGDDHGTQVALVAAAARNDYGVMGIAWGATVQMLRADTPGTCASADGCTFSDT
CCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
NIAEGIDAAVGAGARVVNLSLGGEAADTNLRAAVARATSAGLIVVVSAGNDGQSTDPAID
CHHHCCHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
PNNPDPFAVSLLQAGGGNVIIVGSVSSAGLVSDFSNRAGSSASSFLMAQGETICCVYEGS
CCCCCHHEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCHHEEEECCCEEEEEEECC
QIRVVDGFRTAVNGTSFAAPQVSGAVALLAQAFPNLTGAQIVSLLLSTAREGGAIGTDPI
EEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YGRGILDIARAFSPQGSTGLAGTSVAVSLDSVAGTTSGAMGDAVSGASLGTVMLDGYGRA
CCCHHHHHHHHCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCEEEECCCCCE
YALDLGRGLRFGQARQPLLEALRAGARPTGFEAGDVSLAFSVDRRFGAVPLRLAPGEREQ
EEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCHHH
ARVLASTLVTRIGNARELALGWNTSSDALAARLQKRREAQFLVAGTANGMFERPELGFAA
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHH
RQRFGGMGVTVSGGRSLVWRPEALRDRREDRLARLGVALDGHGGDALDWRLGLGLMREER
HHHCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCEEEECCCCCEEEHHHCCCHHHHHH
TVLGARFADALGGGGATTGTIEPGVTWRPMRGWHVGATGSLGFTRVAGTSVAPGGSRLVS
HHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEECCCCCCCCEEEECCCCCCCCCCCEEC
SSWAFDVARDGALIEGDRLGLRLSQPLRVESGGLALNLPVAWDYATQTARFGRVPLSLAP
CCCEEEECCCCCEEECCCCCEEECCCEEEECCCEEEECCEEECCHHHHHHHCCCCEEECC
KGRELDAEVAWSARLWDGAFSASLFWRRDPGHFAAAPDDAGGAVRWTAGF
CCCCCCCEEEEEEEEECCCCCEEEEEEECCCCEECCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6420308; 9826175 [H]