Click here to switch to the map view.

The map label for this gene is etfD [H]

Identifier: 87199798

GI number: 87199798

Start: 1878453

End: 1880102

Strand: Direct

Name: etfD [H]

Synonym: Saro_1781

Alternate gene names: 87199798

Gene position: 1878453-1880102 (Clockwise)

Preceding gene: 87199792

Following gene: 87199799

Centisome position: 52.74

GC content: 64.18

Gene sequence:

>1650_bases
ATGAGCGAACGGGAATCGATGCCGTATGACGTCGTTATCGTCGGCGGCGGTCCGGCGGGGCTGGCAGCCTCGATCCGGTT
GAAGCAGGTGAATCCCGAAATTTCGGTCTGCATCCTCGAAAAGGGTTCGGAAATCGGCGCGCACATTCTTTCGGGCGCGG
TGGTCGATCCCAAGGCGCTTGACGAACTGCTGCCCGAATGGCGCGAGCAGGGCTGCCCGATGGCCGAAGTGCCCGTGACC
GACAACTGGCATTGGGTGCTCTCGAAGAAGGGCAAGATGTCGATCCCACACTGGCCGATGCCTCCGTTCATGTCGAACGA
CGGCAACTACACCGGTTCGCTCGGCAACCTGTGCCGCTGGCTGGCCGAGCAGGCGATGGAACTGGGCGTGGAAATCTTCC
CCGGCTTTCCTGCCGCCGAAGTGCTGTTCGATGAAAATGGCGCGGTCATGGGCGTCGCGACCGGCGACATGGGCGTGGCC
AAGGACGGTTCGCACAAGCCCGACTACCAGCCGGGCATGGAACTTCACGCCAAGTACACCCTCTTCGCAGAGGGCGCACG
CGGGCATCTGACCAAGCGCCTGAAGGCTCACTTCGACCTCGAGCGCGATTGCGAGCCGCAGGTCTACGGCATCGGCATCA
AGGAACTGTGGGACATCGATCCGGCCAAGCACGTGCCGGGCCGCGTCATTCACACGCAGGGCTGGCCGCTGTCGGAGTCG
AACTCATGGGGCGGTGGTTTCCTTTACCACCAGGCCAACAACCAGGTGGCGCTCGGTTTCGTCACCGCGCTCGATTACGC
CAACCCCTATGTCTATCCGTTCGAGGAATTCCAGCGCTGGAAGCAGCACCCGGAAATCCGCGCGATCCTCGAGGGCGGTC
GCCGCGTTTCCTACGGGGCGCGTGCGATCAACGAGGGTGGCTGGCAGTCCGTGCCGCGCCTGTCGTTCCCTGGCGGCGCG
CTGATCGGTTGCTCCGCAGGCTTCGTCAACGTGCCGCGCATCAAGGGCAGCCACACCGCGATGAAGAGCGGGATGCTGGC
GGCCGATTCCATCGTGGCGGCCATCGCGGCGGGCCGCGAGAAGGACGACATGGTCGAATACGACACTGCCGTCCGCGAAA
GCTGGATCGCCACGGAACTCAAGAAGGTCCAGAACGCGCAGCCGCTCGTCGCCAAGTTCGGCGGTGAACTGGGCACCGTG
CTGGCGGGGGCGGACATGTGGCTTCGCACTGTCGGCGGCTTCGGCATCTGGAAGCCGATGAAGCACCACCGCGACAGCGA
GGCGACCCAGCGCGCCGACCTCTACAAGCCGATCGCCTATCCCAAGCCCGATGGCGTCATCACCTTCGACCGTCTGACCA
GCGTCTCGTTTTCCTATACCAACCACGAGGAGGACCAGCCCTGTCACCTCGTGCTCAAGGACCCGGAGGTGCCGACGCGC
ATCAACCTGCCGCTCTATGCCGGGCCCGAGCAGCGCTATTGCCCGGCGGGCGTCTACGAGTACGTCGGCGTCGAGGAAGG
CAATCCGCGCCTTCAGATCAACGCGCAGAACTGCGTCCACTGCAAGACCTGCGACATCAAGGACATGACCCAGAACATCG
ACTGGGTCACGCCCGAAGGCGGCGGTGGCCCGAACTACCCGAACATGTGA

Upstream 100 bases:

>100_bases
TGCTTCCTCGCAGTTCAATTTGCGGTCTTGACCTCGCCTGTGGCCTCTTTCAAGGCGGAATGCGAAATCAAATGCGCAAT
TAGTCGGGAGTGATCGGGGC

Downstream 100 bases:

>100_bases
TCGGGGCAGGACGAAAATGCAGGAGGCGTCGGGGCTTGCTCCGGCGCCTCTTCCGTTTCAGGGGAGGGCCATGAGTCTGC
GCGAAACCGCCTATGCCAAG

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MSERESMPYDVVIVGGGPAGLAASIRLKQVNPEISVCILEKGSEIGAHILSGAVVDPKALDELLPEWREQGCPMAEVPVT
DNWHWVLSKKGKMSIPHWPMPPFMSNDGNYTGSLGNLCRWLAEQAMELGVEIFPGFPAAEVLFDENGAVMGVATGDMGVA
KDGSHKPDYQPGMELHAKYTLFAEGARGHLTKRLKAHFDLERDCEPQVYGIGIKELWDIDPAKHVPGRVIHTQGWPLSES
NSWGGGFLYHQANNQVALGFVTALDYANPYVYPFEEFQRWKQHPEIRAILEGGRRVSYGARAINEGGWQSVPRLSFPGGA
LIGCSAGFVNVPRIKGSHTAMKSGMLAADSIVAAIAAGREKDDMVEYDTAVRESWIATELKKVQNAQPLVAKFGGELGTV
LAGADMWLRTVGGFGIWKPMKHHRDSEATQRADLYKPIAYPKPDGVITFDRLTSVSFSYTNHEEDQPCHLVLKDPEVPTR
INLPLYAGPEQRYCPAGVYEYVGVEEGNPRLQINAQNCVHCKTCDIKDMTQNIDWVTPEGGGGPNYPNM

Sequences:

>Translated_549_residues
MSERESMPYDVVIVGGGPAGLAASIRLKQVNPEISVCILEKGSEIGAHILSGAVVDPKALDELLPEWREQGCPMAEVPVT
DNWHWVLSKKGKMSIPHWPMPPFMSNDGNYTGSLGNLCRWLAEQAMELGVEIFPGFPAAEVLFDENGAVMGVATGDMGVA
KDGSHKPDYQPGMELHAKYTLFAEGARGHLTKRLKAHFDLERDCEPQVYGIGIKELWDIDPAKHVPGRVIHTQGWPLSES
NSWGGGFLYHQANNQVALGFVTALDYANPYVYPFEEFQRWKQHPEIRAILEGGRRVSYGARAINEGGWQSVPRLSFPGGA
LIGCSAGFVNVPRIKGSHTAMKSGMLAADSIVAAIAAGREKDDMVEYDTAVRESWIATELKKVQNAQPLVAKFGGELGTV
LAGADMWLRTVGGFGIWKPMKHHRDSEATQRADLYKPIAYPKPDGVITFDRLTSVSFSYTNHEEDQPCHLVLKDPEVPTR
INLPLYAGPEQRYCPAGVYEYVGVEEGNPRLQINAQNCVHCKTCDIKDMTQNIDWVTPEGGGGPNYPNM
>Mature_548_residues
SERESMPYDVVIVGGGPAGLAASIRLKQVNPEISVCILEKGSEIGAHILSGAVVDPKALDELLPEWREQGCPMAEVPVTD
NWHWVLSKKGKMSIPHWPMPPFMSNDGNYTGSLGNLCRWLAEQAMELGVEIFPGFPAAEVLFDENGAVMGVATGDMGVAK
DGSHKPDYQPGMELHAKYTLFAEGARGHLTKRLKAHFDLERDCEPQVYGIGIKELWDIDPAKHVPGRVIHTQGWPLSESN
SWGGGFLYHQANNQVALGFVTALDYANPYVYPFEEFQRWKQHPEIRAILEGGRRVSYGARAINEGGWQSVPRLSFPGGAL
IGCSAGFVNVPRIKGSHTAMKSGMLAADSIVAAIAAGREKDDMVEYDTAVRESWIATELKKVQNAQPLVAKFGGELGTVL
AGADMWLRTVGGFGIWKPMKHHRDSEATQRADLYKPIAYPKPDGVITFDRLTSVSFSYTNHEEDQPCHLVLKDPEVPTRI
NLPLYAGPEQRYCPAGVYEYVGVEEGNPRLQINAQNCVHCKTCDIKDMTQNIDWVTPEGGGGPNYPNM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=560, Percent_Identity=53.5714285714286, Blast_Score=590, Evalue=1e-168,
Organism=Escherichia coli, GI1787991, Length=328, Percent_Identity=27.1341463414634, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786227, Length=329, Percent_Identity=25.2279635258359, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082155, Length=382, Percent_Identity=26.1780104712042, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI25144720, Length=560, Percent_Identity=52.1428571428571, Blast_Score=568, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6324932, Length=571, Percent_Identity=44.6584938704028, Blast_Score=459, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24652256, Length=562, Percent_Identity=54.4483985765125, Blast_Score=583, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 60325; Mature: 60194

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERESMPYDVVIVGGGPAGLAASIRLKQVNPEISVCILEKGSEIGAHILSGAVVDPKAL
CCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEECCCHHHHHHHCCCCCCHHHH
DELLPEWREQGCPMAEVPVTDNWHWVLSKKGKMSIPHWPMPPFMSNDGNYTGSLGNLCRW
HHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAEQAMELGVEIFPGFPAAEVLFDENGAVMGVATGDMGVAKDGSHKPDYQPGMELHAKYT
HHHHHHHCCCEEECCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
LFAEGARGHLTKRLKAHFDLERDCEPQVYGIGIKELWDIDPAKHVPGRVIHTQGWPLSES
EEECCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHCCCCCCCCCCEEEEECCCCCCCC
NSWGGGFLYHQANNQVALGFVTALDYANPYVYPFEEFQRWKQHPEIRAILEGGRRVSYGA
CCCCCEEEEEECCCEEEEEEEEEHHCCCCCEEEHHHHHHHHHCCHHHHHHHCCCEEECCH
RAINEGGWQSVPRLSFPGGALIGCSAGFVNVPRIKGSHTAMKSGMLAADSIVAAIAAGRE
HHCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
KDDMVEYDTAVRESWIATELKKVQNAQPLVAKFGGELGTVLAGADMWLRTVGGFGIWKPM
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCHHHHHHHHCCCCCCCCH
KHHRDSEATQRADLYKPIAYPKPDGVITFDRLTSVSFSYTNHEEDQPCHLVLKDPEVPTR
HHCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHCEEEEEECCCCCCCCEEEEEECCCCCCE
INLPLYAGPEQRYCPAGVYEYVGVEEGNPRLQINAQNCVHCKTCDIKDMTQNIDWVTPEG
ECCCEEECCCCCCCCCCHHHEECCCCCCCEEEEECCCCEEEECCCHHHHHCCCCEECCCC
GGGPNYPNM
CCCCCCCCC
>Mature Secondary Structure 
SERESMPYDVVIVGGGPAGLAASIRLKQVNPEISVCILEKGSEIGAHILSGAVVDPKAL
CCCCCCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEECCCHHHHHHHCCCCCCHHHH
DELLPEWREQGCPMAEVPVTDNWHWVLSKKGKMSIPHWPMPPFMSNDGNYTGSLGNLCRW
HHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAEQAMELGVEIFPGFPAAEVLFDENGAVMGVATGDMGVAKDGSHKPDYQPGMELHAKYT
HHHHHHHCCCEEECCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
LFAEGARGHLTKRLKAHFDLERDCEPQVYGIGIKELWDIDPAKHVPGRVIHTQGWPLSES
EEECCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHCCCCCCCCCCEEEEECCCCCCCC
NSWGGGFLYHQANNQVALGFVTALDYANPYVYPFEEFQRWKQHPEIRAILEGGRRVSYGA
CCCCCEEEEEECCCEEEEEEEEEHHCCCCCEEEHHHHHHHHHCCHHHHHHHCCCEEECCH
RAINEGGWQSVPRLSFPGGALIGCSAGFVNVPRIKGSHTAMKSGMLAADSIVAAIAAGRE
HHCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
KDDMVEYDTAVRESWIATELKKVQNAQPLVAKFGGELGTVLAGADMWLRTVGGFGIWKPM
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCHHHHHHHHCCCCCCCCH
KHHRDSEATQRADLYKPIAYPKPDGVITFDRLTSVSFSYTNHEEDQPCHLVLKDPEVPTR
HHCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHCEEEEEECCCCCCCCEEEEEECCCCCCE
INLPLYAGPEQRYCPAGVYEYVGVEEGNPRLQINAQNCVHCKTCDIKDMTQNIDWVTPEG
ECCCEEECCCCCCCCCCHHHEECCCCCCCEEEEECCCCEEEECCCHHHHHCCCCEECCCC
GGGPNYPNM
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]