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The map label for this gene is aroE [H]

Identifier: 87199607

GI number: 87199607

Start: 1650970

End: 1651800

Strand: Direct

Name: aroE [H]

Synonym: Saro_1590

Alternate gene names: 87199607

Gene position: 1650970-1651800 (Clockwise)

Preceding gene: 87199606

Following gene: 87199610

Centisome position: 46.35

GC content: 66.79

Gene sequence:

>831_bases
ATGATGATCCGTTCCGGCCTCGTAGGACGTTCGATCCTCGCCTCCCGCTCTCCCGACCTGCACCAGGGGGAAGGGCGCGC
GCTGGGGCTGGAGGTGAGCTACGAGCTGTTCGACTTTACCGCCCGCGACCTGCCCGACAGTGCATTGGCCGAAGTGATCG
GCACGCTGCGCGACGACGGCTTTGCGGGCTTCAACGTGACCTACCCGTTCAAGCAGGCGATTGTGCCGCTGCTGGACGAA
CTCGACGAGAGCGCATTGGCCGTAGGCGCCGTCAATACCGTGGCGATCCGTGAGGGGCGCCTGATCGGCTACAACACCGA
CATGATCGGTTTTCGCCTGTCGATGGAGCAGGGCCTGCCGGGCGCGAGGCTGGAGCGCGTGGTGCAGCTCGGCGCGGGCG
GAGCGGGCGCGGCGGTGGCCAATGCGCTTCTCTCGCTCGGCGTGCGCAGGCTGGTGCTGGTCGACGTCGACCCGGCCCGC
GCGGAGCAACTGCGCAGCGAACTTGCCGCGCGCTTTCCCGGCCAGGATGTGGAGTGCGGCGCGCCTGGCACGCTGGACAC
CACAGGCGCCGACGGCATCGTCAATGCAACGCCCATAGGCATGAACGGGAAGCCAGGCATGCCGCTGCCACCGGAAAAGA
TTGCTGCGAGGCAGTGGGTGGCCGACATCATCTATTTCCCGAGAGAGACCGAGCTACTTCGGGTCGCGAAGAGCAAGGGA
TGCGCCACTATCAATGGCGTGGGCATGGTCGTGGGCCAGGCGGCACGGGCTTTCGAGATCATCACCGGCCATGCCGCCGA
CGCCCGACGCATGCGCGCAATGCTCGACTGA

Upstream 100 bases:

>100_bases
ATCGGCCGCTCGTTCTACCTTGGCGCCAAGGTCAGCTTCTGATCCACCCTATGTCCCGGCGCCGCCTGCGCGGCTGGCGC
CGGGATTTTTTGAGAAGGCA

Downstream 100 bases:

>100_bases
GTTATTCCGACGGTTGCCAGTTGTGCCCACGGGCGGCGCGCTCGGCTGCGGCATCGAGCGCTGGACCTGCCGCCATTTCC
TGCGCGGCAGCCATGATTTC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MMIRSGLVGRSILASRSPDLHQGEGRALGLEVSYELFDFTARDLPDSALAEVIGTLRDDGFAGFNVTYPFKQAIVPLLDE
LDESALAVGAVNTVAIREGRLIGYNTDMIGFRLSMEQGLPGARLERVVQLGAGGAGAAVANALLSLGVRRLVLVDVDPAR
AEQLRSELAARFPGQDVECGAPGTLDTTGADGIVNATPIGMNGKPGMPLPPEKIAARQWVADIIYFPRETELLRVAKSKG
CATINGVGMVVGQAARAFEIITGHAADARRMRAMLD

Sequences:

>Translated_276_residues
MMIRSGLVGRSILASRSPDLHQGEGRALGLEVSYELFDFTARDLPDSALAEVIGTLRDDGFAGFNVTYPFKQAIVPLLDE
LDESALAVGAVNTVAIREGRLIGYNTDMIGFRLSMEQGLPGARLERVVQLGAGGAGAAVANALLSLGVRRLVLVDVDPAR
AEQLRSELAARFPGQDVECGAPGTLDTTGADGIVNATPIGMNGKPGMPLPPEKIAARQWVADIIYFPRETELLRVAKSKG
CATINGVGMVVGQAARAFEIITGHAADARRMRAMLD
>Mature_276_residues
MMIRSGLVGRSILASRSPDLHQGEGRALGLEVSYELFDFTARDLPDSALAEVIGTLRDDGFAGFNVTYPFKQAIVPLLDE
LDESALAVGAVNTVAIREGRLIGYNTDMIGFRLSMEQGLPGARLERVVQLGAGGAGAAVANALLSLGVRRLVLVDVDPAR
AEQLRSELAARFPGQDVECGAPGTLDTTGADGIVNATPIGMNGKPGMPLPPEKIAARQWVADIIYFPRETELLRVAKSKG
CATINGVGMVVGQAARAFEIITGHAADARRMRAMLD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=275, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789675, Length=271, Percent_Identity=32.1033210332103, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=171, Percent_Identity=32.1637426900585, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29182; Mature: 29182

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIRSGLVGRSILASRSPDLHQGEGRALGLEVSYELFDFTARDLPDSALAEVIGTLRDDG
CCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCC
FAGFNVTYPFKQAIVPLLDELDESALAVGAVNTVAIREGRLIGYNTDMIGFRLSMEQGLP
CCCCEECCCHHHHHHHHHHHHCHHHEECCCCEEEEEECCEEEEECCCEEEEEEEHHCCCC
GARLERVVQLGAGGAGAAVANALLSLGVRRLVLVDVDPARAEQLRSELAARFPGQDVECG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
APGTLDTTGADGIVNATPIGMNGKPGMPLPPEKIAARQWVADIIYFPRETELLRVAKSKG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
CATINGVGMVVGQAARAFEIITGHAADARRMRAMLD
CEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MMIRSGLVGRSILASRSPDLHQGEGRALGLEVSYELFDFTARDLPDSALAEVIGTLRDDG
CCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCC
FAGFNVTYPFKQAIVPLLDELDESALAVGAVNTVAIREGRLIGYNTDMIGFRLSMEQGLP
CCCCEECCCHHHHHHHHHHHHCHHHEECCCCEEEEEECCEEEEECCCEEEEEEEHHCCCC
GARLERVVQLGAGGAGAAVANALLSLGVRRLVLVDVDPARAEQLRSELAARFPGQDVECG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
APGTLDTTGADGIVNATPIGMNGKPGMPLPPEKIAARQWVADIIYFPRETELLRVAKSKG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
CATINGVGMVVGQAARAFEIITGHAADARRMRAMLD
CEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA