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The map label for this gene is oxyR [H]

Identifier: 87199519

GI number: 87199519

Start: 1545008

End: 1545943

Strand: Reverse

Name: oxyR [H]

Synonym: Saro_1501

Alternate gene names: 87199519

Gene position: 1545943-1545008 (Counterclockwise)

Preceding gene: 87199526

Following gene: 87199517

Centisome position: 43.41

GC content: 59.4

Gene sequence:

>936_bases
ATGCTGTCGTTTCGCCAACTGCAATATCTCGTTGCGATCGCCGACCATCAGCACTTCCGACGGGCCGCAACTTACCTGCA
CGTGTCGCAGCCGACCCTTAGTTTGCAAGTGCAGAAGATGGAGGAGCACCTTGGCGTTACGCTGATCGAGCGGGGTGTAA
CGCCGGCAAGGCTTACGCCGGTCGGCCGGGACATCGTGGTCCGCGCTCGAAAACTCTTGCTCGACCTCACTGAACTTGAA
GCTTGCGCGCGCAGTAGTGCGGGCAAGCTGGTCGGCACCATCAGTCTCGGCGTTTCGCCGACCATAGGCCCCTATCTTCT
GCCCGGTATTATCAGTGTGCTGAAGCAGCAGATGCCCCAAGTGAGACTTCACATTCGTGAGGGCATTCCCAGCGAGCATC
TGCTCGAACTGCGGCACGGCGCGCTCGACGTCATGCTGACGCCTGTACCGGCTGCGGGCAGCGATCTGCACTTCGAGACA
CTCTTCGAAGAACGACTGGAGGTTGTGGCCCCGCCCGAGCACCCACTGTCCGGCAAGCAGCCTGTTACAAGGGCAGATCT
TGCCGGAAGCAAGGCGCTTGGCATTGATCCACGCTATCCGTTTCACCAGCAGACCCAGGAAATCTGCGACGACCTTGGGC
TAGATCTGCTGAGCGATTACGAAGGGACAAGTCTCGACAGCCTGTGTCAGATGTGCGCCTCGGGTCTTGGCCTGGCTATC
CTTCCCGAGCTCTATCTGGGATCAGAAGTCGGTGGACGAAACGTGGTGACGGCCCTTCAGATCCAGGATTGGTCCGCGAA
GCGTTCGATTGCAGCCGTCTGGCGGGCTGGCTCGGTTTACACCGAGAGTTTCCACGAGATCGCGCTAGCAATCCAGCGTG
AGGCGCTGCTCTTGCTGGACGATGAACGTCCGGGCACATTTCCCGATAGGAATTGA

Upstream 100 bases:

>100_bases
CTTATCTCTGAGTTGCGGAAAAACCTTGCATGCCTGATTGCGATAGGTCCAATTGAAAGAAACGTAAGAAATTGATAGGT
TTTAACAATCAGGCGGAGTC

Downstream 100 bases:

>100_bases
GCAGATCAGGCAGCACTCTCTTTTGCAGGGCTTGGCCGGAAGCCTTGGGAAAGCGCATGGTAGAGCTTCACGTGGCAAAT
CTTGTTGCTGACCCAATCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MLSFRQLQYLVAIADHQHFRRAATYLHVSQPTLSLQVQKMEEHLGVTLIERGVTPARLTPVGRDIVVRARKLLLDLTELE
ACARSSAGKLVGTISLGVSPTIGPYLLPGIISVLKQQMPQVRLHIREGIPSEHLLELRHGALDVMLTPVPAAGSDLHFET
LFEERLEVVAPPEHPLSGKQPVTRADLAGSKALGIDPRYPFHQQTQEICDDLGLDLLSDYEGTSLDSLCQMCASGLGLAI
LPELYLGSEVGGRNVVTALQIQDWSAKRSIAAVWRAGSVYTESFHEIALAIQREALLLLDDERPGTFPDRN

Sequences:

>Translated_311_residues
MLSFRQLQYLVAIADHQHFRRAATYLHVSQPTLSLQVQKMEEHLGVTLIERGVTPARLTPVGRDIVVRARKLLLDLTELE
ACARSSAGKLVGTISLGVSPTIGPYLLPGIISVLKQQMPQVRLHIREGIPSEHLLELRHGALDVMLTPVPAAGSDLHFET
LFEERLEVVAPPEHPLSGKQPVTRADLAGSKALGIDPRYPFHQQTQEICDDLGLDLLSDYEGTSLDSLCQMCASGLGLAI
LPELYLGSEVGGRNVVTALQIQDWSAKRSIAAVWRAGSVYTESFHEIALAIQREALLLLDDERPGTFPDRN
>Mature_311_residues
MLSFRQLQYLVAIADHQHFRRAATYLHVSQPTLSLQVQKMEEHLGVTLIERGVTPARLTPVGRDIVVRARKLLLDLTELE
ACARSSAGKLVGTISLGVSPTIGPYLLPGIISVLKQQMPQVRLHIREGIPSEHLLELRHGALDVMLTPVPAAGSDLHFET
LFEERLEVVAPPEHPLSGKQPVTRADLAGSKALGIDPRYPFHQQTQEICDDLGLDLLSDYEGTSLDSLCQMCASGLGLAI
LPELYLGSEVGGRNVVTALQIQDWSAKRSIAAVWRAGSVYTESFHEIALAIQREALLLLDDERPGTFPDRN

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=291, Percent_Identity=34.7079037800687, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1788887, Length=201, Percent_Identity=31.8407960199005, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787879, Length=253, Percent_Identity=28.8537549407115, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787601, Length=208, Percent_Identity=30.2884615384615, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI157672245, Length=231, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693105, Length=240, Percent_Identity=26.25, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787530, Length=246, Percent_Identity=24.390243902439, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=27.5303643724696, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790262, Length=278, Percent_Identity=29.4964028776978, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=29.3785310734463, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=267, Percent_Identity=25.0936329588015, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789506, Length=159, Percent_Identity=27.6729559748428, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786401, Length=285, Percent_Identity=23.859649122807, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788748, Length=258, Percent_Identity=26.3565891472868, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788481, Length=245, Percent_Identity=26.9387755102041, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=249, Percent_Identity=23.2931726907631, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34152; Mature: 34152

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFRQLQYLVAIADHQHFRRAATYLHVSQPTLSLQVQKMEEHLGVTLIERGVTPARLTP
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCEEHHHCCCCCHHCCC
VGRDIVVRARKLLLDLTELEACARSSAGKLVGTISLGVSPTIGPYLLPGIISVLKQQMPQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
VRLHIREGIPSEHLLELRHGALDVMLTPVPAAGSDLHFETLFEERLEVVAPPEHPLSGKQ
HHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCC
PVTRADLAGSKALGIDPRYPFHQQTQEICDDLGLDLLSDYEGTSLDSLCQMCASGLGLAI
CCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCHHH
LPELYLGSEVGGRNVVTALQIQDWSAKRSIAAVWRAGSVYTESFHEIALAIQREALLLLD
HHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEE
DERPGTFPDRN
CCCCCCCCCCC
>Mature Secondary Structure
MLSFRQLQYLVAIADHQHFRRAATYLHVSQPTLSLQVQKMEEHLGVTLIERGVTPARLTP
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCEEHHHCCCCCHHCCC
VGRDIVVRARKLLLDLTELEACARSSAGKLVGTISLGVSPTIGPYLLPGIISVLKQQMPQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
VRLHIREGIPSEHLLELRHGALDVMLTPVPAAGSDLHFETLFEERLEVVAPPEHPLSGKQ
HHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCC
PVTRADLAGSKALGIDPRYPFHQQTQEICDDLGLDLLSDYEGTSLDSLCQMCASGLGLAI
CCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCHHH
LPELYLGSEVGGRNVVTALQIQDWSAKRSIAAVWRAGSVYTESFHEIALAIQREALLLLD
HHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEE
DERPGTFPDRN
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]