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The map label for this gene is kdpD [H]

Identifier: 87199517

GI number: 87199517

Start: 1542170

End: 1543456

Strand: Reverse

Name: kdpD [H]

Synonym: Saro_1499

Alternate gene names: 87199517

Gene position: 1543456-1542170 (Counterclockwise)

Preceding gene: 87199519

Following gene: 87199515

Centisome position: 43.34

GC content: 60.84

Gene sequence:

>1287_bases
TTGAACACCGGACCCACAAGCCAGGTTTTCAATTCGAAGCTGAAGAGTGCCCATCCCTGTGATGATCGGGTAAGCGTCGT
TCTCGACGTTGGTGGGGAATGTGGGCGCCTTGTGAAGCTGGGGCACGAGCTGGCAGTCAAACTCGCGCGTTCCTGGGAGG
TCCTCTCGATCGAGACGCCCGCTACAGTCCCAGGCGCAAGCGCCGACAAAAGTATGAGCTTGGCTCTCGCGGAAGCCGCA
GCGCTCGGCGCATCGATCCATCGCGTGTCCGGTGCGACCGTGGCCTCGGCCCTCGAACATCATCTGAAGGGCATGGCGTC
GCCGCATGTGGTTCTGGCTGTGCGGCCGCGCGCGACAATTGCACGTCTCAGGCAGGAATCGCTGGTCGAGCAACTGGCAA
AAGCCATGCCCGGCGCCACTTTCCATGTATTTGGCAGCGCGCAGCCGATACCGGCGGCAAGATCGTGGATTGCCGCGCGC
AGCACGCCCAGGGACATCGTGCTTACGGTGATTGGCGTGATAATCACGATGGCCATCGCGCTGCTGCTGCGCGAGTTTAC
CGGTGCAACTTACCTCAGCATCCTGTTCCTGTTTCCGGTCATCGCAGCTTCGGCAAGGCTTGGTATGATGGCCGCGGCTG
TCGGTGCCTTGCTGTCGACGGTGATGTTCAACCTGTTTTTCCTTGCACCCGGCCTCTCCGCCAATCCCTTGGCCGTCCAA
AGCTGGGTCATGGCGCTCGTCCTGCTCGGGGTTGGTATCTATACATCCATGCTGACAGGTACCTTGCGCAGCAGGATCTA
CCTGAGTGACCGCAATGCGCAGGAAAGCGCTGCACTAGCAGTCTTTGCGCAGGACCTTACGCGGGTTTCCGACTGGACTT
CCACAGCCGAAGTGGTTTGCCGCGAGATAAACCGGATGCTCGGCGCAAATGCGATCGTTGCGCGCGAAATTGCAGGCAAG
TTGGAGATTGCAGGATCCTTTCCAGAAAGCCAGTCGCTCGACCCGCTGGACGAGGCGGCGCTCGACTGGGCCTGGACAAC
TGGGGAGATGACCGGCAGCGGCAGTTCAAATCTTGCCGAGGCGAGCTGGCAGTTCCACCCTCTCAAGACCTCGCTGGGCA
CTCTCGCCGTGCTGGGCATCTCGAAAGGGGATGGACGTGACCCGGTCATGCCGCAGCAGAAGGTTCTTCTGGCGACGATG
ATCGCGCAGGCATCGCTGGCCCATGAACGCTTGCGGCTCGAAGCGGCGACAATCTGCGATTCCCAGTCACGGGAATGCGG
AACCTAA

Upstream 100 bases:

>100_bases
ATCAAAGCTTTGGGGCAATATTGACACGAAGTTCGTTGTCCGCTTGCGCAGGAAGGCGCCGGCAAGGCTGTCCGCAAAGA
TTGGGAAGGTGACCGACGGT

Downstream 100 bases:

>100_bases
GACGACTAGAACGGAAAGAAGTGGTGTATGGCCATTACCGCCACGGCCCATGTCAACAGGTTGAGCGGCAGGCCTACCTT
CATGAAATCCATATAGCGGT

Product: osmosensitive K+ channel histidine kinase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNTGPTSQVFNSKLKSAHPCDDRVSVVLDVGGECGRLVKLGHELAVKLARSWEVLSIETPATVPGASADKSMSLALAEAA
ALGASIHRVSGATVASALEHHLKGMASPHVVLAVRPRATIARLRQESLVEQLAKAMPGATFHVFGSAQPIPAARSWIAAR
STPRDIVLTVIGVIITMAIALLLREFTGATYLSILFLFPVIAASARLGMMAAAVGALLSTVMFNLFFLAPGLSANPLAVQ
SWVMALVLLGVGIYTSMLTGTLRSRIYLSDRNAQESAALAVFAQDLTRVSDWTSTAEVVCREINRMLGANAIVAREIAGK
LEIAGSFPESQSLDPLDEAALDWAWTTGEMTGSGSSNLAEASWQFHPLKTSLGTLAVLGISKGDGRDPVMPQQKVLLATM
IAQASLAHERLRLEAATICDSQSRECGT

Sequences:

>Translated_428_residues
MNTGPTSQVFNSKLKSAHPCDDRVSVVLDVGGECGRLVKLGHELAVKLARSWEVLSIETPATVPGASADKSMSLALAEAA
ALGASIHRVSGATVASALEHHLKGMASPHVVLAVRPRATIARLRQESLVEQLAKAMPGATFHVFGSAQPIPAARSWIAAR
STPRDIVLTVIGVIITMAIALLLREFTGATYLSILFLFPVIAASARLGMMAAAVGALLSTVMFNLFFLAPGLSANPLAVQ
SWVMALVLLGVGIYTSMLTGTLRSRIYLSDRNAQESAALAVFAQDLTRVSDWTSTAEVVCREINRMLGANAIVAREIAGK
LEIAGSFPESQSLDPLDEAALDWAWTTGEMTGSGSSNLAEASWQFHPLKTSLGTLAVLGISKGDGRDPVMPQQKVLLATM
IAQASLAHERLRLEAATICDSQSRECGT
>Mature_428_residues
MNTGPTSQVFNSKLKSAHPCDDRVSVVLDVGGECGRLVKLGHELAVKLARSWEVLSIETPATVPGASADKSMSLALAEAA
ALGASIHRVSGATVASALEHHLKGMASPHVVLAVRPRATIARLRQESLVEQLAKAMPGATFHVFGSAQPIPAARSWIAAR
STPRDIVLTVIGVIITMAIALLLREFTGATYLSILFLFPVIAASARLGMMAAAVGALLSTVMFNLFFLAPGLSANPLAVQ
SWVMALVLLGVGIYTSMLTGTLRSRIYLSDRNAQESAALAVFAQDLTRVSDWTSTAEVVCREINRMLGANAIVAREIAGK
LEIAGSFPESQSLDPLDEAALDWAWTTGEMTGSGSSNLAEASWQFHPLKTSLGTLAVLGISKGDGRDPVMPQQKVLLATM
IAQASLAHERLRLEAATICDSQSRECGT

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=439, Percent_Identity=25.9681093394077, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45190; Mature: 45190

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGPTSQVFNSKLKSAHPCDDRVSVVLDVGGECGRLVKLGHELAVKLARSWEVLSIETP
CCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCC
ATVPGASADKSMSLALAEAAALGASIHRVSGATVASALEHHLKGMASPHVVLAVRPRATI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHHH
ARLRQESLVEQLAKAMPGATFHVFGSAQPIPAARSWIAARSTPRDIVLTVIGVIITMAIA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLLREFTGATYLSILFLFPVIAASARLGMMAAAVGALLSTVMFNLFFLAPGLSANPLAVQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
SWVMALVLLGVGIYTSMLTGTLRSRIYLSDRNAQESAALAVFAQDLTRVSDWTSTAEVVC
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REINRMLGANAIVAREIAGKLEIAGSFPESQSLDPLDEAALDWAWTTGEMTGSGSSNLAE
HHHHHHHCCCHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHCCEEECCCCCCCCCCCHHH
ASWQFHPLKTSLGTLAVLGISKGDGRDPVMPQQKVLLATMIAQASLAHERLRLEAATICD
CCCEEECHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQSRECGT
CCCCCCCC
>Mature Secondary Structure
MNTGPTSQVFNSKLKSAHPCDDRVSVVLDVGGECGRLVKLGHELAVKLARSWEVLSIETP
CCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCC
ATVPGASADKSMSLALAEAAALGASIHRVSGATVASALEHHLKGMASPHVVLAVRPRATI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHHH
ARLRQESLVEQLAKAMPGATFHVFGSAQPIPAARSWIAARSTPRDIVLTVIGVIITMAIA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLLREFTGATYLSILFLFPVIAASARLGMMAAAVGALLSTVMFNLFFLAPGLSANPLAVQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
SWVMALVLLGVGIYTSMLTGTLRSRIYLSDRNAQESAALAVFAQDLTRVSDWTSTAEVVC
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REINRMLGANAIVAREIAGKLEIAGSFPESQSLDPLDEAALDWAWTTGEMTGSGSSNLAE
HHHHHHHCCCHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHCCEEECCCCCCCCCCCHHH
ASWQFHPLKTSLGTLAVLGISKGDGRDPVMPQQKVLLATMIAQASLAHERLRLEAATICD
CCCEEECHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQSRECGT
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]