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The map label for this gene is pamO [H]

Identifier: 87199500

GI number: 87199500

Start: 1521727

End: 1523376

Strand: Reverse

Name: pamO [H]

Synonym: Saro_1480

Alternate gene names: 87199500

Gene position: 1523376-1521727 (Counterclockwise)

Preceding gene: 87199502

Following gene: 87199498

Centisome position: 42.77

GC content: 64.61

Gene sequence:

>1650_bases
GTGGAAGCAGCAGCCGGTCCGGGTTTCGGCGCCCCTGATTTCGATGCAATCGTCATCGGTGCTGGTGTGACGGGAATGTA
TCAGACGTACCTGCTGGACGAGGCGGGGCTTCGGGTGCTTGGTATCGAGGCGGGGGCGGATGTCGGGGGGACCTGGTACT
GGAACCGCTACCCCGGCTGTCGGCTTGACACCGAGAGCTATGCCTACGGTTATTTCGCGCTGAAGGGGATCATTCCTGAA
TGGCGCTGGAGCGAGACGTTCGCCGGCCAGCCCGAGATGCTGCGCTATGCCAATTACGCGGCCGACAAGATGGACGTACG
CCGGCACTACCGCTTCAACACCCGCGTAGAGGCAGCCCGATATGACGACAGCAACAGCTGCTGGCAGGTCACGCTCGACA
GCGGCGAGATCGTCAGCTGCCGGTTCCTGATCTCGGCCACAGGCCCGCTCTCGGCCTCGCGCATGCCCGACTTTGCCGGG
CTCGACAGCTACAAGGGACAGTCGTTCCATTCCTCGCGCTGGCCGACCAACCCCGATGGCAGCGTCCAGGACATCGACTT
TGCCGGTAAGCGCGTCGGCGTCATCGGCACTGGCGCGACTGGCGTCCAGATCATCCCGATCGTCGCCCAGAGCGCGCAGG
AACTGTTCGTGTTCCAGCGCACCCCCAACTGGTGCACCCCGCTCGGCAACTCTCCGCTCAGCGACGAGGACATGGCGCTG
ATCCGCAGCCGTTATCCCACCATCCTCGAATACGTGAAGATCACCGATACCGCCTTCCCCTACCACCGTGACACCCGCAA
GGGCACAGAGGTGCCGGCAGAGGAGCGCGAGGCCTTCTTCGAGGAGCTTTACGACCAGCCCGGATATGGCATCTGGCTGA
GCGGCTTTCGCGATCTCCTGCTCAGCAAGGAATCGAACAAGTTCCTCGCCGACTTCGTCGCCAAGAAGATCCGCCAGCGC
GTGAAGGACCCCGCAGTCGCCGAGAAGCTGATCCCGACCGACCACCCCTTCGGCACCAAGCGGGTGCCGATGGAGACCAA
CTATTACGAGGCCTACAACCGCGACAACGTCCACCTCGTCGACATCCGCGAGGCGCCGATCCAGGGCTTCGAGGCCGGGG
GTATCCGCACCGCCGACGCGTTCTACGATCTCGACGTTGTGATCTTCGCGACCGGCTTCGACGCGGTCACAGGCTCGCTC
GACCGTATCGACATCCGCGGCCGCAACGGCCTGCGCCTCAAGGATGCCTGGTCGGAAGGGCCAAGCACCTACCTGGGCGT
GCAGGCACGCGGCTTCCCCAACTTCTGGACGCTCGTCGGCCCGCACAATGGCTCAGCCTTCTGCAACGTGGGCGTGTGTG
GCGGGCTCCAGGCCGAATGGGTGCTGCGCATGATCGCGTACATGCAGGCACGCGGACTCACCAGTTCGGAGCCCTCCGAG
CGTGCCGAGCAGCGCTGGACCGAGGAAGTCTACCGCGACTTCTCGCGCACCCTCCTCGCAGAAGCCAACGCCTGGTGGGT
CAAGACCACCGAGCGGCCCGACGGAACCATCGAGCGGCGCACCCTCGTCCACGTCGGCGGCGGGCCCGAGTACCGCAAGC
GCTGCGAACAGGTCGCCTACAAAAACTACGAAGGCTTCGAAATGGCCTGA

Upstream 100 bases:

>100_bases
TTCCCGCGTAAAATATTTGCGTCGGACAAAAACTCTGATAACAGCTTTGTATCAGTCAACACCTACGTTGACTCACGATG
AAGAGTTAGGGAGGATGATA

Downstream 100 bases:

>100_bases
GGGGTGATGTTTTCAGGCCTCACGCGTGGTGGTCAGGATGCATCGTTGTCCGATGCATCCACCGCCTCGTGGATGTTGCG
CATGAAGGCTTTGAGTCGCA

Product: cyclohexanone monooxygenase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MEAAAGPGFGAPDFDAIVIGAGVTGMYQTYLLDEAGLRVLGIEAGADVGGTWYWNRYPGCRLDTESYAYGYFALKGIIPE
WRWSETFAGQPEMLRYANYAADKMDVRRHYRFNTRVEAARYDDSNSCWQVTLDSGEIVSCRFLISATGPLSASRMPDFAG
LDSYKGQSFHSSRWPTNPDGSVQDIDFAGKRVGVIGTGATGVQIIPIVAQSAQELFVFQRTPNWCTPLGNSPLSDEDMAL
IRSRYPTILEYVKITDTAFPYHRDTRKGTEVPAEEREAFFEELYDQPGYGIWLSGFRDLLLSKESNKFLADFVAKKIRQR
VKDPAVAEKLIPTDHPFGTKRVPMETNYYEAYNRDNVHLVDIREAPIQGFEAGGIRTADAFYDLDVVIFATGFDAVTGSL
DRIDIRGRNGLRLKDAWSEGPSTYLGVQARGFPNFWTLVGPHNGSAFCNVGVCGGLQAEWVLRMIAYMQARGLTSSEPSE
RAEQRWTEEVYRDFSRTLLAEANAWWVKTTERPDGTIERRTLVHVGGGPEYRKRCEQVAYKNYEGFEMA

Sequences:

>Translated_549_residues
MEAAAGPGFGAPDFDAIVIGAGVTGMYQTYLLDEAGLRVLGIEAGADVGGTWYWNRYPGCRLDTESYAYGYFALKGIIPE
WRWSETFAGQPEMLRYANYAADKMDVRRHYRFNTRVEAARYDDSNSCWQVTLDSGEIVSCRFLISATGPLSASRMPDFAG
LDSYKGQSFHSSRWPTNPDGSVQDIDFAGKRVGVIGTGATGVQIIPIVAQSAQELFVFQRTPNWCTPLGNSPLSDEDMAL
IRSRYPTILEYVKITDTAFPYHRDTRKGTEVPAEEREAFFEELYDQPGYGIWLSGFRDLLLSKESNKFLADFVAKKIRQR
VKDPAVAEKLIPTDHPFGTKRVPMETNYYEAYNRDNVHLVDIREAPIQGFEAGGIRTADAFYDLDVVIFATGFDAVTGSL
DRIDIRGRNGLRLKDAWSEGPSTYLGVQARGFPNFWTLVGPHNGSAFCNVGVCGGLQAEWVLRMIAYMQARGLTSSEPSE
RAEQRWTEEVYRDFSRTLLAEANAWWVKTTERPDGTIERRTLVHVGGGPEYRKRCEQVAYKNYEGFEMA
>Mature_549_residues
MEAAAGPGFGAPDFDAIVIGAGVTGMYQTYLLDEAGLRVLGIEAGADVGGTWYWNRYPGCRLDTESYAYGYFALKGIIPE
WRWSETFAGQPEMLRYANYAADKMDVRRHYRFNTRVEAARYDDSNSCWQVTLDSGEIVSCRFLISATGPLSASRMPDFAG
LDSYKGQSFHSSRWPTNPDGSVQDIDFAGKRVGVIGTGATGVQIIPIVAQSAQELFVFQRTPNWCTPLGNSPLSDEDMAL
IRSRYPTILEYVKITDTAFPYHRDTRKGTEVPAEEREAFFEELYDQPGYGIWLSGFRDLLLSKESNKFLADFVAKKIRQR
VKDPAVAEKLIPTDHPFGTKRVPMETNYYEAYNRDNVHLVDIREAPIQGFEAGGIRTADAFYDLDVVIFATGFDAVTGSL
DRIDIRGRNGLRLKDAWSEGPSTYLGVQARGFPNFWTLVGPHNGSAFCNVGVCGGLQAEWVLRMIAYMQARGLTSSEPSE
RAEQRWTEEVYRDFSRTLLAEANAWWVKTTERPDGTIERRTLVHVGGGPEYRKRCEQVAYKNYEGFEMA

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25145785, Length=248, Percent_Identity=26.2096774193548, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 61605; Mature: 61605

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAAAGPGFGAPDFDAIVIGAGVTGMYQTYLLDEAGLRVLGIEAGADVGGTWYWNRYPGC
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCC
RLDTESYAYGYFALKGIIPEWRWSETFAGQPEMLRYANYAADKMDVRRHYRFNTRVEAAR
EECCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
YDDSNSCWQVTLDSGEIVSCRFLISATGPLSASRMPDFAGLDSYKGQSFHSSRWPTNPDG
CCCCCCEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SVQDIDFAGKRVGVIGTGATGVQIIPIVAQSAQELFVFQRTPNWCTPLGNSPLSDEDMAL
CEEEEECCCCEEEEEECCCCCEEEEEEHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
IRSRYPTILEYVKITDTAFPYHRDTRKGTEVPAEEREAFFEELYDQPGYGIWLSGFRDLL
HHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHH
LSKESNKFLADFVAKKIRQRVKDPAVAEKLIPTDHPFGTKRVPMETNYYEAYNRDNVHLV
HCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEE
DIREAPIQGFEAGGIRTADAFYDLDVVIFATGFDAVTGSLDRIDIRGRNGLRLKDAWSEG
EECCCCCCCCCCCCEEECHHHCCCEEEEEEECCHHHCCCCEEEEECCCCCCEECCCCCCC
PSTYLGVQARGFPNFWTLVGPHNGSAFCNVGVCGGLQAEWVLRMIAYMQARGLTSSEPSE
CCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHH
RAEQRWTEEVYRDFSRTLLAEANAWWVKTTERPDGTIERRTLVHVGGGPEYRKRCEQVAY
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHH
KNYEGFEMA
CCCCCCCCC
>Mature Secondary Structure
MEAAAGPGFGAPDFDAIVIGAGVTGMYQTYLLDEAGLRVLGIEAGADVGGTWYWNRYPGC
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCC
RLDTESYAYGYFALKGIIPEWRWSETFAGQPEMLRYANYAADKMDVRRHYRFNTRVEAAR
EECCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
YDDSNSCWQVTLDSGEIVSCRFLISATGPLSASRMPDFAGLDSYKGQSFHSSRWPTNPDG
CCCCCCEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SVQDIDFAGKRVGVIGTGATGVQIIPIVAQSAQELFVFQRTPNWCTPLGNSPLSDEDMAL
CEEEEECCCCEEEEEECCCCCEEEEEEHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
IRSRYPTILEYVKITDTAFPYHRDTRKGTEVPAEEREAFFEELYDQPGYGIWLSGFRDLL
HHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHH
LSKESNKFLADFVAKKIRQRVKDPAVAEKLIPTDHPFGTKRVPMETNYYEAYNRDNVHLV
HCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEE
DIREAPIQGFEAGGIRTADAFYDLDVVIFATGFDAVTGSLDRIDIRGRNGLRLKDAWSEG
EECCCCCCCCCCCCEEECHHHCCCEEEEEEECCHHHCCCCEEEEECCCCCCEECCCCCCC
PSTYLGVQARGFPNFWTLVGPHNGSAFCNVGVCGGLQAEWVLRMIAYMQARGLTSSEPSE
CCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHH
RAEQRWTEEVYRDFSRTLLAEANAWWVKTTERPDGTIERRTLVHVGGGPEYRKRCEQVAY
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHH
KNYEGFEMA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA