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The map label for this gene is fusA [C]

Identifier: 87199298

GI number: 87199298

Start: 1316192

End: 1318252

Strand: Reverse

Name: fusA [C]

Synonym: Saro_1277

Alternate gene names: 87199298

Gene position: 1318252-1316192 (Counterclockwise)

Preceding gene: 87199301

Following gene: 87199295

Centisome position: 37.01

GC content: 67.88

Gene sequence:

>2061_bases
ATGGGCGACACCACAAATACAGGCACCACCCCTCACGGCAGCAGGCCAGGCCGGACCGGCAGCGCGCCGCGCATGATCGC
GCTGGTCGGTCCGGCAGGAACCGGCAAGACCACTCTCGCCGAGGCCCTGCTTCACGCGAGCGGCGCGATCAACCGGCAGG
GGAGCGTCGAGGCGGGCACATCCGTCGGCGATGCATCACCCGAGGCGCGGGCGCGGCGAGGATCGACCGAACTGAACCTG
TGCCGCCTTGAATATCTCGGCGACACCTTTGTCCTTGCCGATGCCCCCGGCAGTACCGGTTTCGCCGTCGATGCCGATCT
TGCGCTGCAGATGGCGGACATGGCGATCGTGGTCGTCGATCCGGTGGCGGATCGGGCGGCGCTGGCCGGCCCGATCCTGC
GCCGGCTCGACGAACTCGAATTGCCACACGCGATCTTCGTCAACAGGATGGACGGAGCGCGGGCGGGCTCTGTGCGCGAG
ATCCTGTCCGCGCTCCAGCCCCTCAGCCGCGAGCCGCTGATGCTGCGGCAGTTTCCGATCCGGCAGGGCGAGGAAATTAC
CGGGTTCGTCGACGTCGCACTCGAACGCGCGTGGCGCTACCGTCCCGGCCAGCCCTCCGAACCCATTCCCATGCCCGAGG
ACGTGGGCCTGCGCGAAAAAGGCGAACGCCAGCAATTGCTCGAAACCCTGGCGGACTTCGACGACGCGCTGATGGAAGCC
CTGCTGATGGACGAGGAGCCGGACCCAGCCACGATCCTTGCCGACCTCGCGGTCGATACGGCGACGAACCGCGTGGTCCC
CGTACTGTTCGGCTCCGCGCTTACGGGAGGAGGAATGCGCCGCCTGCTCAAGCTGCTGCGACACGAAGCTCCAGATCCCC
ACGCCGCCGCCGCGCGTCTGGGACTGGACGACGAGCCGGCGCTTGCGGTGTTCAAGGTAACGACGGGCGGTGCGATGGGC
CGTCTGGCGCTGGGTCGTGTGTTCGGAGCCGCATTGCGTGAAGGCACCGAACTTGCGGGAACGCGGGTCGGGTCGCTGTT
CCGGATGCAGGGCGACAAGACCAACAAGACCGCCGATGCAGATGCCGGCGATGTCGTCGCTGTGGCCAAGCTCGAGCAAG
CAAGGCCTGGCACGATCCTTGGGCGTTCGGGGCTTCTGGCGGAATTGACGCCCGCGATCCCGGCACGCAACACCGCGCTC
GCCATCGCCACGCGCGACCGGCGCGACGACGTGAAGCTATCGGCGGCGCTGCACCGTCTTTGCGAGGAAGACCCGGCACT
TGCCTGGGAGCAGGACGGCGACAGCCACGAGACCCTGCTTCGCGGGATCAACGACGAGCATCTTGCCGTTGTCCTGGCGC
GGTTGAAGCGGCGTTACGGGGTGGAGGTCACTTCATCGCCGCCCCGCGTCGCCTACCGCGAGACCATCCGCAAGGAAGCC
GGCGCGCGAGGACGCCACAAGAAGCAATCGGGCGGGCATGGCCAGTTCGGCGACGCGGTGATCGAAATTCGCCCCCTTTC
GCGCGGTGAAGGATTCGCCTTCGAGGACCGGATCACCGGCGGAGCCATCCCCAGGCAATGGATCCCGGCAGTCGAAGCGG
GCGCGCGCGATGCGATGATGAAAGGACCGCTCGGCTTCCCCGTGGTCGACGTCGCGGTGACCTTGCTCGACGGGTCGTTC
CATTCGGTGGACAGCTCGGAACTTGCGTTCCGGACCGCCGGCCGCATGGCGATGGCCGAGGCACTGGAAAAGGCCTCGCC
ATGCCTGCTCGAACCCGTCTTTCGGGTCAGCGTGGACATGCCGGCGGGGACCGGCGCGAAGGCCGGGTCGGCGCTTTCGG
CACGGCGCGGCCAGATCCTCGGCCTCGACCAGCATCCTGAGTGGGAGCGCTGGGAGCGCGTCGAGGCGCTGTTGCCCGAA
GCGGCGTTGCACGGGCTCGACGCAGAATTGCGCGCGTTGAGCCAGGGTCTCGCGAGCTTCACCGCGACGTTCGACCACAT
GACTGAACTGGCGGGCAAGCACGCGGACGATGCCATCCGCATGCAGGCCAAGGCCGCTTGA

Upstream 100 bases:

>100_bases
GCTTGCGACTCAGGGCCATGAGGCAGACCATCGGTTCAGGTCCCTTGCGCGTCAGGGCACTCCGTACAGCGCCCGGCGCG
CCCCCGCAGGAGAGGCGACG

Downstream 100 bases:

>100_bases
TGCCAACGGAGGGCCCCGAAGGCGACGACTACATGTTGAAGTAGGCGCCGCCCTTCTCCCGCGCCCGCTGCCAGGCGGGG
CGTGCATGGACCGCTGCCAC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MGDTTNTGTTPHGSRPGRTGSAPRMIALVGPAGTGKTTLAEALLHASGAINRQGSVEAGTSVGDASPEARARRGSTELNL
CRLEYLGDTFVLADAPGSTGFAVDADLALQMADMAIVVVDPVADRAALAGPILRRLDELELPHAIFVNRMDGARAGSVRE
ILSALQPLSREPLMLRQFPIRQGEEITGFVDVALERAWRYRPGQPSEPIPMPEDVGLREKGERQQLLETLADFDDALMEA
LLMDEEPDPATILADLAVDTATNRVVPVLFGSALTGGGMRRLLKLLRHEAPDPHAAAARLGLDDEPALAVFKVTTGGAMG
RLALGRVFGAALREGTELAGTRVGSLFRMQGDKTNKTADADAGDVVAVAKLEQARPGTILGRSGLLAELTPAIPARNTAL
AIATRDRRDDVKLSAALHRLCEEDPALAWEQDGDSHETLLRGINDEHLAVVLARLKRRYGVEVTSSPPRVAYRETIRKEA
GARGRHKKQSGGHGQFGDAVIEIRPLSRGEGFAFEDRITGGAIPRQWIPAVEAGARDAMMKGPLGFPVVDVAVTLLDGSF
HSVDSSELAFRTAGRMAMAEALEKASPCLLEPVFRVSVDMPAGTGAKAGSALSARRGQILGLDQHPEWERWERVEALLPE
AALHGLDAELRALSQGLASFTATFDHMTELAGKHADDAIRMQAKAA

Sequences:

>Translated_686_residues
MGDTTNTGTTPHGSRPGRTGSAPRMIALVGPAGTGKTTLAEALLHASGAINRQGSVEAGTSVGDASPEARARRGSTELNL
CRLEYLGDTFVLADAPGSTGFAVDADLALQMADMAIVVVDPVADRAALAGPILRRLDELELPHAIFVNRMDGARAGSVRE
ILSALQPLSREPLMLRQFPIRQGEEITGFVDVALERAWRYRPGQPSEPIPMPEDVGLREKGERQQLLETLADFDDALMEA
LLMDEEPDPATILADLAVDTATNRVVPVLFGSALTGGGMRRLLKLLRHEAPDPHAAAARLGLDDEPALAVFKVTTGGAMG
RLALGRVFGAALREGTELAGTRVGSLFRMQGDKTNKTADADAGDVVAVAKLEQARPGTILGRSGLLAELTPAIPARNTAL
AIATRDRRDDVKLSAALHRLCEEDPALAWEQDGDSHETLLRGINDEHLAVVLARLKRRYGVEVTSSPPRVAYRETIRKEA
GARGRHKKQSGGHGQFGDAVIEIRPLSRGEGFAFEDRITGGAIPRQWIPAVEAGARDAMMKGPLGFPVVDVAVTLLDGSF
HSVDSSELAFRTAGRMAMAEALEKASPCLLEPVFRVSVDMPAGTGAKAGSALSARRGQILGLDQHPEWERWERVEALLPE
AALHGLDAELRALSQGLASFTATFDHMTELAGKHADDAIRMQAKAA
>Mature_685_residues
GDTTNTGTTPHGSRPGRTGSAPRMIALVGPAGTGKTTLAEALLHASGAINRQGSVEAGTSVGDASPEARARRGSTELNLC
RLEYLGDTFVLADAPGSTGFAVDADLALQMADMAIVVVDPVADRAALAGPILRRLDELELPHAIFVNRMDGARAGSVREI
LSALQPLSREPLMLRQFPIRQGEEITGFVDVALERAWRYRPGQPSEPIPMPEDVGLREKGERQQLLETLADFDDALMEAL
LMDEEPDPATILADLAVDTATNRVVPVLFGSALTGGGMRRLLKLLRHEAPDPHAAAARLGLDDEPALAVFKVTTGGAMGR
LALGRVFGAALREGTELAGTRVGSLFRMQGDKTNKTADADAGDVVAVAKLEQARPGTILGRSGLLAELTPAIPARNTALA
IATRDRRDDVKLSAALHRLCEEDPALAWEQDGDSHETLLRGINDEHLAVVLARLKRRYGVEVTSSPPRVAYRETIRKEAG
ARGRHKKQSGGHGQFGDAVIEIRPLSRGEGFAFEDRITGGAIPRQWIPAVEAGARDAMMKGPLGFPVVDVAVTLLDGSFH
SVDSSELAFRTAGRMAMAEALEKASPCLLEPVFRVSVDMPAGTGAKAGSALSARRGQILGLDQHPEWERWERVEALLPEA
ALHGLDAELRALSQGLASFTATFDHMTELAGKHADDAIRMQAKAA

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=701, Percent_Identity=28.2453637660485, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI19923640, Length=693, Percent_Identity=26.984126984127, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI25306287, Length=254, Percent_Identity=30.3149606299213, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI25306283, Length=327, Percent_Identity=29.3577981651376, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1789738, Length=699, Percent_Identity=30.0429184549356, Blast_Score=286, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17533571, Length=675, Percent_Identity=27.4074074074074, Blast_Score=241, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17556745, Length=670, Percent_Identity=23.7313432835821, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323098, Length=676, Percent_Identity=29.1420118343195, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6322359, Length=704, Percent_Identity=22.4431818181818, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24582462, Length=698, Percent_Identity=28.9398280802292, Blast_Score=242, Evalue=5e-64,
Organism=Drosophila melanogaster, GI221458488, Length=694, Percent_Identity=25.2161383285303, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 73042; Mature: 72911

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTTNTGTTPHGSRPGRTGSAPRMIALVGPAGTGKTTLAEALLHASGAINRQGSVEAGT
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
SVGDASPEARARRGSTELNLCRLEYLGDTFVLADAPGSTGFAVDADLALQMADMAIVVVD
CCCCCCCHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCEECHHHHHHHCCEEEEEEC
PVADRAALAGPILRRLDELELPHAIFVNRMDGARAGSVREILSALQPLSREPLMLRQFPI
CCHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCC
RQGEEITGFVDVALERAWRYRPGQPSEPIPMPEDVGLREKGERQQLLETLADFDDALMEA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLMDEEPDPATILADLAVDTATNRVVPVLFGSALTGGGMRRLLKLLRHEAPDPHAAAARL
HHCCCCCCCHHHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHC
GLDDEPALAVFKVTTGGAMGRLALGRVFGAALREGTELAGTRVGSLFRMQGDKTNKTADA
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCC
DAGDVVAVAKLEQARPGTILGRSGLLAELTPAIPARNTALAIATRDRRDDVKLSAALHRL
CCCCEEEEEEHHCCCCCEEECCCCCHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
CEEDPALAWEQDGDSHETLLRGINDEHLAVVLARLKRRYGVEVTSSPPRVAYRETIRKEA
HCCCCCCEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHH
GARGRHKKQSGGHGQFGDAVIEIRPLSRGEGFAFEDRITGGAIPRQWIPAVEAGARDAMM
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCCCCCHHHCCHHHCCCHHHHH
KGPLGFPVVDVAVTLLDGSFHSVDSSELAFRTAGRMAMAEALEKASPCLLEPVFRVSVDM
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHEEECC
PAGTGAKAGSALSARRGQILGLDQHPEWERWERVEALLPEAALHGLDAELRALSQGLASF
CCCCCCCCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TATFDHMTELAGKHADDAIRMQAKAA
HHHHHHHHHHHCCCCCHHHHHHCCCC
>Mature Secondary Structure 
GDTTNTGTTPHGSRPGRTGSAPRMIALVGPAGTGKTTLAEALLHASGAINRQGSVEAGT
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
SVGDASPEARARRGSTELNLCRLEYLGDTFVLADAPGSTGFAVDADLALQMADMAIVVVD
CCCCCCCHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCEECHHHHHHHCCEEEEEEC
PVADRAALAGPILRRLDELELPHAIFVNRMDGARAGSVREILSALQPLSREPLMLRQFPI
CCHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCC
RQGEEITGFVDVALERAWRYRPGQPSEPIPMPEDVGLREKGERQQLLETLADFDDALMEA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLMDEEPDPATILADLAVDTATNRVVPVLFGSALTGGGMRRLLKLLRHEAPDPHAAAARL
HHCCCCCCCHHHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHC
GLDDEPALAVFKVTTGGAMGRLALGRVFGAALREGTELAGTRVGSLFRMQGDKTNKTADA
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCC
DAGDVVAVAKLEQARPGTILGRSGLLAELTPAIPARNTALAIATRDRRDDVKLSAALHRL
CCCCEEEEEEHHCCCCCEEECCCCCHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
CEEDPALAWEQDGDSHETLLRGINDEHLAVVLARLKRRYGVEVTSSPPRVAYRETIRKEA
HCCCCCCEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHH
GARGRHKKQSGGHGQFGDAVIEIRPLSRGEGFAFEDRITGGAIPRQWIPAVEAGARDAMM
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCCCCCHHHCCHHHCCCHHHHH
KGPLGFPVVDVAVTLLDGSFHSVDSSELAFRTAGRMAMAEALEKASPCLLEPVFRVSVDM
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHEEECC
PAGTGAKAGSALSARRGQILGLDQHPEWERWERVEALLPEAALHGLDAELRALSQGLASF
CCCCCCCCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TATFDHMTELAGKHADDAIRMQAKAA
HHHHHHHHHHHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]