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The map label for this gene is yhcY [H]

Identifier: 87199259

GI number: 87199259

Start: 1287922

End: 1289565

Strand: Reverse

Name: yhcY [H]

Synonym: Saro_1237

Alternate gene names: 87199259

Gene position: 1289565-1287922 (Counterclockwise)

Preceding gene: 87199294

Following gene: 87199258

Centisome position: 36.21

GC content: 67.03

Gene sequence:

>1644_bases
GTGAGCGCGAAGGGATGGACACGCAGGACCGGTCGCGTGATCGCGACGGGGCGTGCCGTACTCGCGCTGACCTTTCTCCT
CGCGCTCTGGCTCGATCCGGTGGTCCCGGTCCGCGGGGTGACGCTGGGTTACGCGCTGGTCAGCAGCTACCTGCTGTGGA
CGGCGCTGCTGATGATCATCGCCTGGCGGAGCTGGTGGTACGACTTCAGGCTCGCCCCGGTCGCCCAGGTCGTGGACATC
CTGATGTTCCTGTCGGCGGTCTACTTCACCGAAAGTCCCTTCACCGAATTCCAGAGCCCGTTCCTGGCCTTCGCAGCCTT
CATGCAGGTCAGCGCGATGGTGCGGTGGAATTGGCGCGCGACGGCGCTGACAGCGCTCGTCCTGCTCAGCACCAACCTCG
CGTTCGGCATCACGTTGTACCAGATGGGGCTGGACATCGACCTGTTCCGGTTCTCGCGGCGCACGATCTACATGATCGTG
CTGTCCTCGATCCTCATCTGGCTCAGCATGTCGCGCGGGAGCGGGCGAACCGTGGCGTTTGCCGAGCCTCCGGGCATTCC
GGGCGAACGACGCGACCTGCTGCTTGACAGCGCGCTCCGGGCGGCGGCGGCAACCCTCGGTGCCGAGCAGGTCGCCCTGG
CCTTCGCGGCGAGCGAAGAACCGTGGATCGAAATGCGGCGGCTCACGGCAAAGGGGATCGTGACCGAACGGCTTGCCCCC
GAGGGCCTTGCCGACGAACTCCTCGGTCGGCGCTCGACCGCAATCTTCAGCCGCTCGCGAAAGCGCCAGCTCGCTCTGGC
CGAAGACGGTGGGCTCGAGGCACTGGACGGGCCGGTCGAATCCCGCCTTGCCGACCTGCTCGGGGCAGACGAAGGCATCA
TCGCCTCAGTGCAGAGCGTGACCGGATCGGGCCATCTCGTCGCCTGGGACCACAAGAACCTGAGCTTCGACGACATCGCG
CTGGTGCGGGCCCTGGCGGACGAGATCGGGCACGCGCTGGACCGCGAGGAAATGGCGCGGCTGGCCCGCAGCGCCGCCGA
GACCGGGGTTCGCCAGGCCGTCGCCCGAGACCTGCACGACAGCGTGGCACAGTTCCTCGCAGGGACGTTGTTCCGCCTGG
AAGCGCTGCGCCGCTGGATCCGCGAGGGCAACGATCCCGAGGGCGAGATAGATTCCATCAAGAATGCCCTGCGCCGCGAG
CAAGGACAGTTGCGCCTCCTGATCCAGCGCCTGCGTCGCGGGCAGGAAGGCGACCGGCGCACCGAGATCGGCGAGGAACT
GCGCGATCTGCTGGCCGAGGCCAGCGGCCATTGGCACATCGAGACCGAGCTGGTCATGGACCAGCGCCCCCTGCCGGTTT
CCGTACAGCTCAGCCACGAGATCAGGCAGCTCGTGCGCGAGGCAGTGGCCAACGCGGCGCGCCATGGCAAATGCGGAAAA
GTGAAGGTCGAGCTTTCGGAACAGGCCGGCCACCTCAACCTTGCCATTACCGATGACGGCAAAGGGTTTCCCCAGATCCC
CAATGCCCCCCGCCCCCGCTCGATCAGCGAACGCGTCGAGGCACTGGGCGGTCGCTTCGAACTTCACAGCGACGGGGCCG
GAACGCGCCTCGCCATTGCCCTAAGATCCGGAGAACCTGCATGA

Upstream 100 bases:

>100_bases
AATATGAAAGTAACCGTTACCGTCCCTATTTCATACGGCGCCGCTATCCGCGCTTGCGCGGTTCGTGCAGGGTAGCAGGG
GCGAATCGGAAGGGGATAAA

Downstream 100 bases:

>100_bases
TTCCTGTTCTGGTTGCTGACGACCATGGCTTCATCCGCGCCGGTGTCGAAGCCGTGTTGCGGGGCACGCGTTTCTCCGTC
GTGGCAACCACGGCGAGTGG

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSAKGWTRRTGRVIATGRAVLALTFLLALWLDPVVPVRGVTLGYALVSSYLLWTALLMIIAWRSWWYDFRLAPVAQVVDI
LMFLSAVYFTESPFTEFQSPFLAFAAFMQVSAMVRWNWRATALTALVLLSTNLAFGITLYQMGLDIDLFRFSRRTIYMIV
LSSILIWLSMSRGSGRTVAFAEPPGIPGERRDLLLDSALRAAAATLGAEQVALAFAASEEPWIEMRRLTAKGIVTERLAP
EGLADELLGRRSTAIFSRSRKRQLALAEDGGLEALDGPVESRLADLLGADEGIIASVQSVTGSGHLVAWDHKNLSFDDIA
LVRALADEIGHALDREEMARLARSAAETGVRQAVARDLHDSVAQFLAGTLFRLEALRRWIREGNDPEGEIDSIKNALRRE
QGQLRLLIQRLRRGQEGDRRTEIGEELRDLLAEASGHWHIETELVMDQRPLPVSVQLSHEIRQLVREAVANAARHGKCGK
VKVELSEQAGHLNLAITDDGKGFPQIPNAPRPRSISERVEALGGRFELHSDGAGTRLAIALRSGEPA

Sequences:

>Translated_547_residues
MSAKGWTRRTGRVIATGRAVLALTFLLALWLDPVVPVRGVTLGYALVSSYLLWTALLMIIAWRSWWYDFRLAPVAQVVDI
LMFLSAVYFTESPFTEFQSPFLAFAAFMQVSAMVRWNWRATALTALVLLSTNLAFGITLYQMGLDIDLFRFSRRTIYMIV
LSSILIWLSMSRGSGRTVAFAEPPGIPGERRDLLLDSALRAAAATLGAEQVALAFAASEEPWIEMRRLTAKGIVTERLAP
EGLADELLGRRSTAIFSRSRKRQLALAEDGGLEALDGPVESRLADLLGADEGIIASVQSVTGSGHLVAWDHKNLSFDDIA
LVRALADEIGHALDREEMARLARSAAETGVRQAVARDLHDSVAQFLAGTLFRLEALRRWIREGNDPEGEIDSIKNALRRE
QGQLRLLIQRLRRGQEGDRRTEIGEELRDLLAEASGHWHIETELVMDQRPLPVSVQLSHEIRQLVREAVANAARHGKCGK
VKVELSEQAGHLNLAITDDGKGFPQIPNAPRPRSISERVEALGGRFELHSDGAGTRLAIALRSGEPA
>Mature_546_residues
SAKGWTRRTGRVIATGRAVLALTFLLALWLDPVVPVRGVTLGYALVSSYLLWTALLMIIAWRSWWYDFRLAPVAQVVDIL
MFLSAVYFTESPFTEFQSPFLAFAAFMQVSAMVRWNWRATALTALVLLSTNLAFGITLYQMGLDIDLFRFSRRTIYMIVL
SSILIWLSMSRGSGRTVAFAEPPGIPGERRDLLLDSALRAAAATLGAEQVALAFAASEEPWIEMRRLTAKGIVTERLAPE
GLADELLGRRSTAIFSRSRKRQLALAEDGGLEALDGPVESRLADLLGADEGIIASVQSVTGSGHLVAWDHKNLSFDDIAL
VRALADEIGHALDREEMARLARSAAETGVRQAVARDLHDSVAQFLAGTLFRLEALRRWIREGNDPEGEIDSIKNALRREQ
GQLRLLIQRLRRGQEGDRRTEIGEELRDLLAEASGHWHIETELVMDQRPLPVSVQLSHEIRQLVREAVANAARHGKCGKV
KVELSEQAGHLNLAITDDGKGFPQIPNAPRPRSISERVEALGGRFELHSDGAGTRLAIALRSGEPA

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=257, Percent_Identity=28.4046692607004, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60404; Mature: 60273

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKGWTRRTGRVIATGRAVLALTFLLALWLDPVVPVRGVTLGYALVSSYLLWTALLMII
CCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AWRSWWYDFRLAPVAQVVDILMFLSAVYFTESPFTEFQSPFLAFAAFMQVSAMVRWNWRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
TALTALVLLSTNLAFGITLYQMGLDIDLFRFSRRTIYMIVLSSILIWLSMSRGSGRTVAF
HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
AEPPGIPGERRDLLLDSALRAAAATLGAEQVALAFAASEEPWIEMRRLTAKGIVTERLAP
ECCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
EGLADELLGRRSTAIFSRSRKRQLALAEDGGLEALDGPVESRLADLLGADEGIIASVQSV
CCHHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHC
TGSGHLVAWDHKNLSFDDIALVRALADEIGHALDREEMARLARSAAETGVRQAVARDLHD
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAQFLAGTLFRLEALRRWIREGNDPEGEIDSIKNALRREQGQLRLLIQRLRRGQEGDRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TEIGEELRDLLAEASGHWHIETELVMDQRPLPVSVQLSHEIRQLVREAVANAARHGKCGK
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCE
VKVELSEQAGHLNLAITDDGKGFPQIPNAPRPRSISERVEALGGRFELHSDGAGTRLAIA
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEE
LRSGEPA
ECCCCCC
>Mature Secondary Structure 
SAKGWTRRTGRVIATGRAVLALTFLLALWLDPVVPVRGVTLGYALVSSYLLWTALLMII
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AWRSWWYDFRLAPVAQVVDILMFLSAVYFTESPFTEFQSPFLAFAAFMQVSAMVRWNWRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
TALTALVLLSTNLAFGITLYQMGLDIDLFRFSRRTIYMIVLSSILIWLSMSRGSGRTVAF
HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
AEPPGIPGERRDLLLDSALRAAAATLGAEQVALAFAASEEPWIEMRRLTAKGIVTERLAP
ECCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
EGLADELLGRRSTAIFSRSRKRQLALAEDGGLEALDGPVESRLADLLGADEGIIASVQSV
CCHHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHC
TGSGHLVAWDHKNLSFDDIALVRALADEIGHALDREEMARLARSAAETGVRQAVARDLHD
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAQFLAGTLFRLEALRRWIREGNDPEGEIDSIKNALRREQGQLRLLIQRLRRGQEGDRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TEIGEELRDLLAEASGHWHIETELVMDQRPLPVSVQLSHEIRQLVREAVANAARHGKCGK
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCE
VKVELSEQAGHLNLAITDDGKGFPQIPNAPRPRSISERVEALGGRFELHSDGAGTRLAIA
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEE
LRSGEPA
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]