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The map label for this gene is argG [H]

Identifier: 87199217

GI number: 87199217

Start: 1242494

End: 1243708

Strand: Reverse

Name: argG [H]

Synonym: Saro_1195

Alternate gene names: 87199217

Gene position: 1243708-1242494 (Counterclockwise)

Preceding gene: 87199219

Following gene: 87199215

Centisome position: 34.92

GC content: 65.93

Gene sequence:

>1215_bases
ATGTCCGATATCAAGAAGGTCGTCCTCGCCTACTCCGGCGGTCTCGACACCTCCGTCATCCTCAAGTGGCTGCAGGTCAC
CTACAACTGCGAGGTGGTCACCTTCACCGCCGACCTCGGCCAGGGCGAGGAGCTCGAACCCGCGCGCGCCAAGGCAAAGC
TGATGGGCGTGCCCGATCACCACATCTACATCGACGACCTGCGCGAGGAATTCGTGCGCGACTTCGTCTTCCCGATGATG
CGCGCCAATGCCCGCTACGAGGGCGATTACCTGCTCGGCACCTCGATCGCCCGTCCGCTGATCTCCAAGCGCCTGATCGA
AATCGCGCGCGAAACCGGAGCCGATGCCGTCGCCCACGGCGCGACCGGCAAGGGCAACGACCAGGTCCGCTTCGAACTGT
CCGCCTACGCCCTCGAACCGGGCATCAAGGTTATCGCGCCCTGGCGCGAATGGGATCTCACCAGCCGCACCGCGCTGATC
GCCTGGGCCGAAGCGCACCAGATTCCGGTCCCCAAGGACAAGCGCGGCGAAAGCCCGTTCTCGACCGACGCCAACCTCCT
CCACACCTCGTCCGAAGGCAAGGTGCTGGAAGATCCGTGGCAGGAAACCCCGGACTACGTCTACTCGCGCACCGTCAATC
CGGAAGACGCGCCCGACACCCCTGAGTACATCACCATCGACTTCGAGAAGGGCGATGGCGTCGCGCTCAACGGCGAGGCC
ATGTCGCCCGCCACGCTGCTCGCCGCCCTCAACGACCTCGGCCGCAAGCACGGCATCGGCCGTCTCGATCTCGTCGAGAA
CCGCTTCGTCGGCATGAAGAGCCGCGGCATGTACGAAACGCCCGGCGGCGAGATCTATGCCCGTGCCCATCGCGGCATCG
AAAGCATCACCCTCGACCGGGGCGCGGCGCACCTCAAGGACGAGCTGATGCCCAAGTACGCGGAGCTGATCTACAACGGC
TTCTGGTTCTCGCCCGAGCGCGAGATGCTGCAGGCCGCGATCGATCACTCGCAGGCCCGCGTGAACGGCACCGTCCGGCT
CAAGCTCTACAAGGGCAGCGCCTCGGTCGTCGGCCGCAAGTCGCCCGACAGCCTCTACTCCGAACGCCACGTGACGTTCG
AGGACGATGCCGGCGCCTACGACCAGAAGGACGCGGCGGGCTTCATCAAGCTCAACGCCCTGCGCCTTCGCCTGCTGGCG
CAGCAGGGCCGCTGA

Upstream 100 bases:

>100_bases
GCATTCTGCGAGGGATGGCCCAGCCTGCCCGGCAAAGGTTGCGATGTTGGACCTCGCCTGTTAGTCGCGCGGCGCGTAAT
TCACGGGAGTCGTAGCGCCC

Downstream 100 bases:

>100_bases
TCGCCGCGCTTCGGCGCTGCACAAGAGCTATCCACCGAAGAGTGCGGGGGTTGTGGATAACTCCCGCACTTTTCGCTTGC
GCGACTCGGACGAGAGGCGC

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSDIKKVVLAYSGGLDTSVILKWLQVTYNCEVVTFTADLGQGEELEPARAKAKLMGVPDHHIYIDDLREEFVRDFVFPMM
RANARYEGDYLLGTSIARPLISKRLIEIARETGADAVAHGATGKGNDQVRFELSAYALEPGIKVIAPWREWDLTSRTALI
AWAEAHQIPVPKDKRGESPFSTDANLLHTSSEGKVLEDPWQETPDYVYSRTVNPEDAPDTPEYITIDFEKGDGVALNGEA
MSPATLLAALNDLGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIESITLDRGAAHLKDELMPKYAELIYNG
FWFSPEREMLQAAIDHSQARVNGTVRLKLYKGSASVVGRKSPDSLYSERHVTFEDDAGAYDQKDAAGFIKLNALRLRLLA
QQGR

Sequences:

>Translated_404_residues
MSDIKKVVLAYSGGLDTSVILKWLQVTYNCEVVTFTADLGQGEELEPARAKAKLMGVPDHHIYIDDLREEFVRDFVFPMM
RANARYEGDYLLGTSIARPLISKRLIEIARETGADAVAHGATGKGNDQVRFELSAYALEPGIKVIAPWREWDLTSRTALI
AWAEAHQIPVPKDKRGESPFSTDANLLHTSSEGKVLEDPWQETPDYVYSRTVNPEDAPDTPEYITIDFEKGDGVALNGEA
MSPATLLAALNDLGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIESITLDRGAAHLKDELMPKYAELIYNG
FWFSPEREMLQAAIDHSQARVNGTVRLKLYKGSASVVGRKSPDSLYSERHVTFEDDAGAYDQKDAAGFIKLNALRLRLLA
QQGR
>Mature_403_residues
SDIKKVVLAYSGGLDTSVILKWLQVTYNCEVVTFTADLGQGEELEPARAKAKLMGVPDHHIYIDDLREEFVRDFVFPMMR
ANARYEGDYLLGTSIARPLISKRLIEIARETGADAVAHGATGKGNDQVRFELSAYALEPGIKVIAPWREWDLTSRTALIA
WAEAHQIPVPKDKRGESPFSTDANLLHTSSEGKVLEDPWQETPDYVYSRTVNPEDAPDTPEYITIDFEKGDGVALNGEAM
SPATLLAALNDLGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIESITLDRGAAHLKDELMPKYAELIYNGF
WFSPEREMLQAAIDHSQARVNGTVRLKLYKGSASVVGRKSPDSLYSERHVTFEDDAGAYDQKDAAGFIKLNALRLRLLAQ
QGR

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=406, Percent_Identity=46.551724137931, Blast_Score=359, Evalue=3e-99,
Organism=Homo sapiens, GI16950633, Length=406, Percent_Identity=46.551724137931, Blast_Score=359, Evalue=3e-99,
Organism=Escherichia coli, GI1789563, Length=423, Percent_Identity=27.1867612293144, Blast_Score=124, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6324514, Length=407, Percent_Identity=43.2432432432432, Blast_Score=321, Evalue=2e-88,
Organism=Drosophila melanogaster, GI21358151, Length=404, Percent_Identity=45.5445544554455, Blast_Score=332, Evalue=3e-91,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 44929; Mature: 44798

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIKKVVLAYSGGLDTSVILKWLQVTYNCEVVTFTADLGQGEELEPARAKAKLMGVPDH
CCHHHEEHHHCCCCCCHHHHHHHHHHEECCEEEEEEECCCCCCCCCHHHHHHEEECCCCC
HIYIDDLREEFVRDFVFPMMRANARYEGDYLLGTSIARPLISKRLIEIARETGADAVAHG
EEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHCCC
ATGKGNDQVRFELSAYALEPGIKVIAPWREWDLTSRTALIAWAEAHQIPVPKDKRGESPF
CCCCCCCEEEEEEEEEEECCCCEEEECCHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
STDANLLHTSSEGKVLEDPWQETPDYVYSRTVNPEDAPDTPEYITIDFEKGDGVALNGEA
CCCCCEEEECCCCCEECCCHHCCCCHHEECCCCCCCCCCCCCEEEEEEECCCCEEECCCC
MSPATLLAALNDLGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIESITLDR
CCHHHHHHHHHHHHHHCCCCCEEEHHCCCCCCCCCCCEECCCCCEEEHHHCCCCEEEECC
GAAHLKDELMPKYAELIYNGFWFSPEREMLQAAIDHSQARVNGTVRLKLYKGSASVVGRK
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECEEEEEEEEECCCCCCCCC
SPDSLYSERHVTFEDDAGAYDQKDAAGFIKLNALRLRLLAQQGR
CCHHHHHCCCCEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
SDIKKVVLAYSGGLDTSVILKWLQVTYNCEVVTFTADLGQGEELEPARAKAKLMGVPDH
CHHHEEHHHCCCCCCHHHHHHHHHHEECCEEEEEEECCCCCCCCCHHHHHHEEECCCCC
HIYIDDLREEFVRDFVFPMMRANARYEGDYLLGTSIARPLISKRLIEIARETGADAVAHG
EEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHCCC
ATGKGNDQVRFELSAYALEPGIKVIAPWREWDLTSRTALIAWAEAHQIPVPKDKRGESPF
CCCCCCCEEEEEEEEEEECCCCEEEECCHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
STDANLLHTSSEGKVLEDPWQETPDYVYSRTVNPEDAPDTPEYITIDFEKGDGVALNGEA
CCCCCEEEECCCCCEECCCHHCCCCHHEECCCCCCCCCCCCCEEEEEEECCCCEEECCCC
MSPATLLAALNDLGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIESITLDR
CCHHHHHHHHHHHHHHCCCCCEEEHHCCCCCCCCCCCEECCCCCEEEHHHCCCCEEEECC
GAAHLKDELMPKYAELIYNGFWFSPEREMLQAAIDHSQARVNGTVRLKLYKGSASVVGRK
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECEEEEEEEEECCCCCCCCC
SPDSLYSERHVTFEDDAGAYDQKDAAGFIKLNALRLRLLAQQGR
CCHHHHHCCCCEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA