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The map label for this gene is thiL [H]

Identifier: 87199090

GI number: 87199090

Start: 1112500

End: 1113414

Strand: Reverse

Name: thiL [H]

Synonym: Saro_1068

Alternate gene names: 87199090

Gene position: 1113414-1112500 (Counterclockwise)

Preceding gene: 87199097

Following gene: 87199089

Centisome position: 31.26

GC content: 68.52

Gene sequence:

>915_bases
TTGTGGAGACAGCCGCTCCACCCCATAGACCGGGGCGTGAGCAAGGAATCCGCCCTGATCGAAGCGATGCGCGCGCTGGC
CACGCACCCGGCCGCCCGCGCCCTCGCGGACGATTGCGCAGTGCTGGACTTCGGCGGCGAAACGATGGTCCTGACCCACG
ACATGATGGTCGAGGGCGTGCACTGGCTGCCGGGGCAGGACATGGCGGATGTGGCGTGGAAGCTGGTGGCGACGAACCTG
TCGGACCTTGCATCCAAGGGCGCGGAACCTGTCGGCGTCCTGCTGGGGTATACGCTCGACAACGATGAAGACGCGCGCTT
CATCGAAGGGCTCGGTGCGGCGCTGGCGACCTTCGGCGTTCCGCTGCTGGGCGGCGACACGGTAAGCGGCAATGGCCCGC
GCAGCCTCGGCCTGACTGCCCTGGGCCGCGCGACTTCACATCCCGTGCCCGACCGGCGCGGCGCCAGGGTGGGCGATGTG
CTGTGGATCACCGGCCCGGTCGGAGCGGCGATGCTCGGGTTCGAGGCGCTGCGCGATGGCACCGCCGCGGACAGCACGGC
CTTTCGTCGGCCCGTGCCACGCCTTGCCGAAGGTCGCGCGCTGGCAGGCATGGTCACGGCTATGATGGACGTGTCCGACG
GCCTGCTGATCGATGCAGCGCGCATGGCGGATGCCAGCAACGTGACTTTCGCCATCGACAGTGCCTCGGTCGCCTTCCCG
CCCGCCCTTCCCGCCACGCGCCGCGACGAGGCGATGCGCTGGGGCGATGATTACGAGTTGCTGTTCTGCCTTCCCGCACG
ATCGGTTCCACCGATCCCTGCCGTTCGCATCGGCCATGCTGTAGCCCGCATGGCAACAGCCGTTACGGTCGACGGCGTGC
CACCCGAGGGTCGGCTCGGTTATTCGCACGATTAA

Upstream 100 bases:

>100_bases
CCGCATCGACGATATAGGCTGTAGCCATTTCTTCTCCGACTCCTCTCGAATACTCTTTAATCGAACGATTAAGGACCGCA
AGGCCGCTGGTCAAGCAGGC

Downstream 100 bases:

>100_bases
AAACCGACTGGCGCACCGCATCGAAGGACTTGCGGGGCGGGAATAAACCTATAGCTTCCGCCCGACCCGCAACGACGGGG
ACGGATCATTCGTGGTCCGG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MWRQPLHPIDRGVSKESALIEAMRALATHPAARALADDCAVLDFGGETMVLTHDMMVEGVHWLPGQDMADVAWKLVATNL
SDLASKGAEPVGVLLGYTLDNDEDARFIEGLGAALATFGVPLLGGDTVSGNGPRSLGLTALGRATSHPVPDRRGARVGDV
LWITGPVGAAMLGFEALRDGTAADSTAFRRPVPRLAEGRALAGMVTAMMDVSDGLLIDAARMADASNVTFAIDSASVAFP
PALPATRRDEAMRWGDDYELLFCLPARSVPPIPAVRIGHAVARMATAVTVDGVPPEGRLGYSHD

Sequences:

>Translated_304_residues
MWRQPLHPIDRGVSKESALIEAMRALATHPAARALADDCAVLDFGGETMVLTHDMMVEGVHWLPGQDMADVAWKLVATNL
SDLASKGAEPVGVLLGYTLDNDEDARFIEGLGAALATFGVPLLGGDTVSGNGPRSLGLTALGRATSHPVPDRRGARVGDV
LWITGPVGAAMLGFEALRDGTAADSTAFRRPVPRLAEGRALAGMVTAMMDVSDGLLIDAARMADASNVTFAIDSASVAFP
PALPATRRDEAMRWGDDYELLFCLPARSVPPIPAVRIGHAVARMATAVTVDGVPPEGRLGYSHD
>Mature_304_residues
MWRQPLHPIDRGVSKESALIEAMRALATHPAARALADDCAVLDFGGETMVLTHDMMVEGVHWLPGQDMADVAWKLVATNL
SDLASKGAEPVGVLLGYTLDNDEDARFIEGLGAALATFGVPLLGGDTVSGNGPRSLGLTALGRATSHPVPDRRGARVGDV
LWITGPVGAAMLGFEALRDGTAADSTAFRRPVPRLAEGRALAGMVTAMMDVSDGLLIDAARMADASNVTFAIDSASVAFP
PALPATRRDEAMRWGDDYELLFCLPARSVPPIPAVRIGHAVARMATAVTVDGVPPEGRLGYSHD

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=251, Percent_Identity=35.8565737051793, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 31910; Mature: 31910

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRQPLHPIDRGVSKESALIEAMRALATHPAARALADDCAVLDFGGETMVLTHDMMVEGV
CCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCEEEECCCCEEEEEHHHHHCCC
HWLPGQDMADVAWKLVATNLSDLASKGAEPVGVLLGYTLDNDEDARFIEGLGAALATFGV
CCCCCCCHHHHHHHHHHHCHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC
PLLGGDTVSGNGPRSLGLTALGRATSHPVPDRRGARVGDVLWITGPVGAAMLGFEALRDG
EEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCC
TAADSTAFRRPVPRLAEGRALAGMVTAMMDVSDGLLIDAARMADASNVTFAIDSASVAFP
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCEEEEECCCCEECC
PALPATRRDEAMRWGDDYELLFCLPARSVPPIPAVRIGHAVARMATAVTVDGVPPEGRLG
CCCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCC
YSHD
CCCC
>Mature Secondary Structure
MWRQPLHPIDRGVSKESALIEAMRALATHPAARALADDCAVLDFGGETMVLTHDMMVEGV
CCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCEEEECCCCEEEEEHHHHHCCC
HWLPGQDMADVAWKLVATNLSDLASKGAEPVGVLLGYTLDNDEDARFIEGLGAALATFGV
CCCCCCCHHHHHHHHHHHCHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC
PLLGGDTVSGNGPRSLGLTALGRATSHPVPDRRGARVGDVLWITGPVGAAMLGFEALRDG
EEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCC
TAADSTAFRRPVPRLAEGRALAGMVTAMMDVSDGLLIDAARMADASNVTFAIDSASVAFP
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCEEEEECCCCEECC
PALPATRRDEAMRWGDDYELLFCLPARSVPPIPAVRIGHAVARMATAVTVDGVPPEGRLG
CCCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCC
YSHD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]