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The map label for this gene is lldD

Identifier: 87199072

GI number: 87199072

Start: 1089104

End: 1090249

Strand: Reverse

Name: lldD

Synonym: Saro_1050

Alternate gene names: 87199072

Gene position: 1090249-1089104 (Counterclockwise)

Preceding gene: 87199073

Following gene: 87199071

Centisome position: 30.61

GC content: 66.06

Gene sequence:

>1146_bases
ATGATCGCCGCCTCGATCCCCGATTTCCGGGAGCTTGCCCGCCGCCGCCTGCCGCATTTTCTGTTCGAATACATCGACGG
CGGCTCCTACAGCGAGACCACGCTTCGCCGGAACGTCGAGGACTTGCGCGATATCGCGCTGCGCCAGCGCGTGCTGCGCG
ACGTGTCCGGACTTGACCTGTCGACCGAACTGTTCGGCCAGAAGGTGGCCCTTCCCGTCGCCCTCGCCCCAATCGGCCTT
GCAGGGATGAACGCACGGCGCGGCGAATGCCAGGCGGTGCGCGCGGCGGAAACCGCGGGGATACCTTTTACGCTGTCCAC
CGTATCGGCCTGCTCGCTCGCCGAAGTCGCGGGCGCGGCATCGAAGCCGTTCTGGTTCCAGCTCTACATGACGCGCGACC
GCGGCTTCATGCGCGAATTGCTTCAGGAAGCGGTCGAGCTGAAGTGTTCGACCCTGGTCTTCACCGTCGACATGCCGGTG
CCGGGCAGTCGATACCGCGATTATCACTCCGGCCTTGCCGGCGCGTCGGGCATGAAGGGCGCGCTGCGGCGCACCCTGCA
AGGTGCAATGAAGCCCGGCTGGGCTTGGGACGTCGGCGTCATGGGGCGCCCGCATGGCCTCGGCAACGTCGTGCGCAAGC
TCGATGGCAAGACCGGCATCGAGGACTTCTTTGCCTGGATGCGCAACAACTTCGACAGCTCCATCGCTTGGAGCGACCTC
GATTTCATCCGTTCGGAATGGAACGGACCTCTGGTCATCAAGGGCTTGCTCGATCCTGAAGATGCGGTGGAAGCCGCCAA
CCTCGGCGCGGACGGTATCGTCGTCTCGAACCACGGCGGCCGCCAGCTCGATGGCGTGCTGTCGAGCGCGAAGGCCCTTC
CCGCCATCGCCGATGCCGTGGGCGATCGCATGACCGTGCTCGCCGATGGCGGCGTCCGTTCGGGCCTGGATGTCGTTCGC
CTGCTGGCACTGGGCGCCAAGGGCGTGTTGCTCGGCCGCGCGTGGGTGTTTGCGCTGGCGGCACAGGGGCAGGCCGGGGT
CGAACACATGCTGCGGCTGATCGAGGCGGAGATGCGCGTCGCCATGACGCTGACCGGCGTGAAGAACATCGGTGAGATCG
ACCGCTCGATCCTCGCCAGCAGATAA

Upstream 100 bases:

>100_bases
CTCGACACCGGATCGTGGGCCGATCTCGATACCTACCGCAACCGCTGGCAGGCCGAGGTCGAAGCTGCAAAAGTGGAGCC
CATTACGTGAGCAACGCCGC

Downstream 100 bases:

>100_bases
AAGAACGAAGGGACAGGATACCGATGGGCGCAAACCCCGCACTGGGCGTGATCTTCCACTGGCTGGGCGGCTTCTCGTCG
GCCAGCTTCTACGTGCCGTA

Product: L-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MIAASIPDFRELARRRLPHFLFEYIDGGSYSETTLRRNVEDLRDIALRQRVLRDVSGLDLSTELFGQKVALPVALAPIGL
AGMNARRGECQAVRAAETAGIPFTLSTVSACSLAEVAGAASKPFWFQLYMTRDRGFMRELLQEAVELKCSTLVFTVDMPV
PGSRYRDYHSGLAGASGMKGALRRTLQGAMKPGWAWDVGVMGRPHGLGNVVRKLDGKTGIEDFFAWMRNNFDSSIAWSDL
DFIRSEWNGPLVIKGLLDPEDAVEAANLGADGIVVSNHGGRQLDGVLSSAKALPAIADAVGDRMTVLADGGVRSGLDVVR
LLALGAKGVLLGRAWVFALAAQGQAGVEHMLRLIEAEMRVAMTLTGVKNIGEIDRSILASR

Sequences:

>Translated_381_residues
MIAASIPDFRELARRRLPHFLFEYIDGGSYSETTLRRNVEDLRDIALRQRVLRDVSGLDLSTELFGQKVALPVALAPIGL
AGMNARRGECQAVRAAETAGIPFTLSTVSACSLAEVAGAASKPFWFQLYMTRDRGFMRELLQEAVELKCSTLVFTVDMPV
PGSRYRDYHSGLAGASGMKGALRRTLQGAMKPGWAWDVGVMGRPHGLGNVVRKLDGKTGIEDFFAWMRNNFDSSIAWSDL
DFIRSEWNGPLVIKGLLDPEDAVEAANLGADGIVVSNHGGRQLDGVLSSAKALPAIADAVGDRMTVLADGGVRSGLDVVR
LLALGAKGVLLGRAWVFALAAQGQAGVEHMLRLIEAEMRVAMTLTGVKNIGEIDRSILASR
>Mature_381_residues
MIAASIPDFRELARRRLPHFLFEYIDGGSYSETTLRRNVEDLRDIALRQRVLRDVSGLDLSTELFGQKVALPVALAPIGL
AGMNARRGECQAVRAAETAGIPFTLSTVSACSLAEVAGAASKPFWFQLYMTRDRGFMRELLQEAVELKCSTLVFTVDMPV
PGSRYRDYHSGLAGASGMKGALRRTLQGAMKPGWAWDVGVMGRPHGLGNVVRKLDGKTGIEDFFAWMRNNFDSSIAWSDL
DFIRSEWNGPLVIKGLLDPEDAVEAANLGADGIVVSNHGGRQLDGVLSSAKALPAIADAVGDRMTVLADGGVRSGLDVVR
LLALGAKGVLLGRAWVFALAAQGQAGVEHMLRLIEAEMRVAMTLTGVKNIGEIDRSILASR

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=376, Percent_Identity=34.5744680851064, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI54234014, Length=379, Percent_Identity=34.8284960422164, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI7705393, Length=379, Percent_Identity=34.8284960422164, Blast_Score=216, Evalue=2e-56,
Organism=Escherichia coli, GI1790033, Length=378, Percent_Identity=63.2275132275132, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI193208036, Length=373, Percent_Identity=32.4396782841823, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI32566217, Length=289, Percent_Identity=29.757785467128, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6323587, Length=382, Percent_Identity=30.1047120418848, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI78707188, Length=379, Percent_Identity=36.9393139841689, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI281363140, Length=379, Percent_Identity=36.9393139841689, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI78707190, Length=379, Percent_Identity=36.9393139841689, Blast_Score=219, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 41124; Mature: 41124

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAASIPDFRELARRRLPHFLFEYIDGGSYSETTLRRNVEDLRDIALRQRVLRDVSGLDL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
STELFGQKVALPVALAPIGLAGMNARRGECQAVRAAETAGIPFTLSTVSACSLAEVAGAA
CHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCC
SKPFWFQLYMTRDRGFMRELLQEAVELKCSTLVFTVDMPVPGSRYRDYHSGLAGASGMKG
CCCEEEEEEEECCHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCHHH
ALRRTLQGAMKPGWAWDVGVMGRPHGLGNVVRKLDGKTGIEDFFAWMRNNFDSSIAWSDL
HHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHH
DFIRSEWNGPLVIKGLLDPEDAVEAANLGADGIVVSNHGGRQLDGVLSSAKALPAIADAV
HHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHC
GDRMTVLADGGVRSGLDVVRLLALGAKGVLLGRAWVFALAAQGQAGVEHMLRLIEAEMRV
CCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AMTLTGVKNIGEIDRSILASR
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAASIPDFRELARRRLPHFLFEYIDGGSYSETTLRRNVEDLRDIALRQRVLRDVSGLDL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
STELFGQKVALPVALAPIGLAGMNARRGECQAVRAAETAGIPFTLSTVSACSLAEVAGAA
CHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCC
SKPFWFQLYMTRDRGFMRELLQEAVELKCSTLVFTVDMPVPGSRYRDYHSGLAGASGMKG
CCCEEEEEEEECCHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCHHH
ALRRTLQGAMKPGWAWDVGVMGRPHGLGNVVRKLDGKTGIEDFFAWMRNNFDSSIAWSDL
HHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHH
DFIRSEWNGPLVIKGLLDPEDAVEAANLGADGIVVSNHGGRQLDGVLSSAKALPAIADAV
HHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHC
GDRMTVLADGGVRSGLDVVRLLALGAKGVLLGRAWVFALAAQGQAGVEHMLRLIEAEMRV
CCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AMTLTGVKNIGEIDRSILASR
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA