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The map label for this gene is gutA [H]

Identifier: 87199019

GI number: 87199019

Start: 1040458

End: 1041885

Strand: Reverse

Name: gutA [H]

Synonym: Saro_0997

Alternate gene names: 87199019

Gene position: 1041885-1040458 (Counterclockwise)

Preceding gene: 87199020

Following gene: 87199018

Centisome position: 29.25

GC content: 67.44

Gene sequence:

>1428_bases
ATGATCCCGATACAGGGCAAGGTTCCCACCCGCCTCGCCCTGTTCAACGGGCTTGGCAGCGTGGCCTACGGCATCAAGGA
CAATGGCTTCGCCACGTTCCTGCTGCTGTTCTACAATCAGGTCCTGGGCATGGATGCGCGGCTGGTGAGCCTCGCGCTGC
TGATCGCACTGGTGTTCGACGGGCTGATCGATCCGGTCGTCGGTCATATCAGCGATCGCACGCGCACGCATTGGGGCCGG
CGACTGCCGTTCCTCTACCTCGCCCCGATCCCGCTGGGCCTGGCCTGGATATTCCTGTGGTCGCCCATCGGCGAGCCAAG
CTTCGCGATGCTGCTGATGTCGGCGATCATGGTGCGCGCGCTGGTGGCCATGTGCGAGGTCCCCTCGGCAGCGCTGGTCG
CCGAAATCAGTCGCGACTACGATGAGCGGACCCGCCTTACCCGGTTCCGCTTCCTGTTCTCGTGGGGCGGCGGACTGCTG
ATGCTGCTGCTCGCCTATGGGGTGTTCCTGCCCAACGCCATGCTGGCGCGCGAGGGATACCGCAACTTCGGCCTGTTCGG
CGCCGGGCTGATGGTGGCCTGCGTCCTGCTTTCCGCCATCGGGCAGCACCGGGCCGTGGCAGGCATGCCTCCCGAGCGCG
CGACGGCGGACAAGGGCGCCCTCGCCTCGCTGGGCGAGATCCGCGAAAGCTTCTCGCACCCTGCGTGCCTCGTCGTCATG
GCGGGAATCGCGGCGGCCCTGACCGCGCAGGGGATTACATTCGCGCTTTCGAATTACCTCTATCTCTACGTGTGGAAGTT
CACGCCGACCGCGCTCAAGGCCTTCCCCTTCCTGCTTTTCGCCAGCGTCGTGGGCGCGTCGCTGCTGGTGGGCAAGGCGC
AGGCGCGTTGGGGAAAGGCGGGGACCGTGATCCGCATGGCACCGCTCGGCATGGTCTTCTGGGCGGGACCCCTGATCCTG
CGCTGGCTGGGGCTGTGGGCTCCGGACGGATCGACCGCGTCGATCGCGGGCATGTTCGCCTGCACGCTCCTGTCGAACAC
GTTTACCGTCACGGGCACGATGACCCTGTGGTCGATGGTCGCGGACGTCGTCGAGGCTTCGGAGGAGCAGACGGGACGCC
GCTCCGAAGGAACGCTTTCGGCCGGCGCATTCCTCGCCTCGAAGTGCGCCGGGGGACTGGGCGTATTCCTGACCGGGCTC
CTGCTGAGCTTCGCGGGGCTCGAGGCGAACACGGCGCCTGCCGACGTGCTGCCCGAAGTCACCTATCGCCTGAGCCTTGC
CTATGCGGCGAGCATCGCGCTCCTGGCCGTGCTGACGGCGCTGGTCGTGCAACGCTTCCCGATCGACCGGGCCGCACACG
AGGCGCGGCTGGCGAGGCTCGACCAGGTGGCGAGGGTCGATCCGGACGCCGCGGGCCTTCATCCTTGA

Upstream 100 bases:

>100_bases
TCGATGGCGGCATCACCGTGGGCCCGCGCCATAGCTGGGACCCGAACATGCCCGGCCTGTTCGATGCGCTGCAGCAGATG
AAGGAAAGCGGCAAGGTTTC

Downstream 100 bases:

>100_bases
CATGGATCGGGCGCGCCCATTAACCGAACGCTTAATTTTGACTTGAAAACACCACAGGCCCGATGGACAGTGCCGGGCGA
GAAGGAGACGATCATGGATT

Product: Na+/melibiose symporter and related transporters-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MIPIQGKVPTRLALFNGLGSVAYGIKDNGFATFLLLFYNQVLGMDARLVSLALLIALVFDGLIDPVVGHISDRTRTHWGR
RLPFLYLAPIPLGLAWIFLWSPIGEPSFAMLLMSAIMVRALVAMCEVPSAALVAEISRDYDERTRLTRFRFLFSWGGGLL
MLLLAYGVFLPNAMLAREGYRNFGLFGAGLMVACVLLSAIGQHRAVAGMPPERATADKGALASLGEIRESFSHPACLVVM
AGIAAALTAQGITFALSNYLYLYVWKFTPTALKAFPFLLFASVVGASLLVGKAQARWGKAGTVIRMAPLGMVFWAGPLIL
RWLGLWAPDGSTASIAGMFACTLLSNTFTVTGTMTLWSMVADVVEASEEQTGRRSEGTLSAGAFLASKCAGGLGVFLTGL
LLSFAGLEANTAPADVLPEVTYRLSLAYAASIALLAVLTALVVQRFPIDRAAHEARLARLDQVARVDPDAAGLHP

Sequences:

>Translated_475_residues
MIPIQGKVPTRLALFNGLGSVAYGIKDNGFATFLLLFYNQVLGMDARLVSLALLIALVFDGLIDPVVGHISDRTRTHWGR
RLPFLYLAPIPLGLAWIFLWSPIGEPSFAMLLMSAIMVRALVAMCEVPSAALVAEISRDYDERTRLTRFRFLFSWGGGLL
MLLLAYGVFLPNAMLAREGYRNFGLFGAGLMVACVLLSAIGQHRAVAGMPPERATADKGALASLGEIRESFSHPACLVVM
AGIAAALTAQGITFALSNYLYLYVWKFTPTALKAFPFLLFASVVGASLLVGKAQARWGKAGTVIRMAPLGMVFWAGPLIL
RWLGLWAPDGSTASIAGMFACTLLSNTFTVTGTMTLWSMVADVVEASEEQTGRRSEGTLSAGAFLASKCAGGLGVFLTGL
LLSFAGLEANTAPADVLPEVTYRLSLAYAASIALLAVLTALVVQRFPIDRAAHEARLARLDQVARVDPDAAGLHP
>Mature_475_residues
MIPIQGKVPTRLALFNGLGSVAYGIKDNGFATFLLLFYNQVLGMDARLVSLALLIALVFDGLIDPVVGHISDRTRTHWGR
RLPFLYLAPIPLGLAWIFLWSPIGEPSFAMLLMSAIMVRALVAMCEVPSAALVAEISRDYDERTRLTRFRFLFSWGGGLL
MLLLAYGVFLPNAMLAREGYRNFGLFGAGLMVACVLLSAIGQHRAVAGMPPERATADKGALASLGEIRESFSHPACLVVM
AGIAAALTAQGITFALSNYLYLYVWKFTPTALKAFPFLLFASVVGASLLVGKAQARWGKAGTVIRMAPLGMVFWAGPLIL
RWLGLWAPDGSTASIAGMFACTLLSNTFTVTGTMTLWSMVADVVEASEEQTGRRSEGTLSAGAFLASKCAGGLGVFLTGL
LLSFAGLEANTAPADVLPEVTYRLSLAYAASIALLAVLTALVVQRFPIDRAAHEARLARLDQVARVDPDAAGLHP

Specific function: Probably involved in glucitol uptake [H]

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Escherichia coli, GI1786466, Length=492, Percent_Identity=24.7967479674797, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI145693206, Length=449, Percent_Identity=26.7260579064588, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI48994989, Length=449, Percent_Identity=24.9443207126949, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082306, Length=435, Percent_Identity=23.9080459770115, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787902, Length=470, Percent_Identity=22.3404255319149, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50792; Mature: 50792

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPIQGKVPTRLALFNGLGSVAYGIKDNGFATFLLLFYNQVLGMDARLVSLALLIALVFD
CCCCCCCCCHHHHHHHCHHHHEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLIDPVVGHISDRTRTHWGRRLPFLYLAPIPLGLAWIFLWSPIGEPSFAMLLMSAIMVRA
HHHHHHHHHHCHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LVAMCEVPSAALVAEISRDYDERTRLTRFRFLFSWGGGLLMLLLAYGVFLPNAMLAREGY
HHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCC
RNFGLFGAGLMVACVLLSAIGQHRAVAGMPPERATADKGALASLGEIRESFSHPACLVVM
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
AGIAAALTAQGITFALSNYLYLYVWKFTPTALKAFPFLLFASVVGASLLVGKAQARWGKA
HHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTVIRMAPLGMVFWAGPLILRWLGLWAPDGSTASIAGMFACTLLSNTFTVTGTMTLWSMV
CCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHH
ADVVEASEEQTGRRSEGTLSAGAFLASKCAGGLGVFLTGLLLSFAGLEANTAPADVLPEV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
TYRLSLAYAASIALLAVLTALVVQRFPIDRAAHEARLARLDQVARVDPDAAGLHP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIPIQGKVPTRLALFNGLGSVAYGIKDNGFATFLLLFYNQVLGMDARLVSLALLIALVFD
CCCCCCCCCHHHHHHHCHHHHEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLIDPVVGHISDRTRTHWGRRLPFLYLAPIPLGLAWIFLWSPIGEPSFAMLLMSAIMVRA
HHHHHHHHHHCHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LVAMCEVPSAALVAEISRDYDERTRLTRFRFLFSWGGGLLMLLLAYGVFLPNAMLAREGY
HHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCC
RNFGLFGAGLMVACVLLSAIGQHRAVAGMPPERATADKGALASLGEIRESFSHPACLVVM
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
AGIAAALTAQGITFALSNYLYLYVWKFTPTALKAFPFLLFASVVGASLLVGKAQARWGKA
HHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTVIRMAPLGMVFWAGPLILRWLGLWAPDGSTASIAGMFACTLLSNTFTVTGTMTLWSMV
CCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHH
ADVVEASEEQTGRRSEGTLSAGAFLASKCAGGLGVFLTGLLLSFAGLEANTAPADVLPEV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
TYRLSLAYAASIALLAVLTALVVQRFPIDRAAHEARLARLDQVARVDPDAAGLHP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]