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The map label for this gene is mltA [H]

Identifier: 87198607

GI number: 87198607

Start: 629263

End: 630486

Strand: Reverse

Name: mltA [H]

Synonym: Saro_0583

Alternate gene names: 87198607

Gene position: 630486-629263 (Counterclockwise)

Preceding gene: 87198608

Following gene: 87198606

Centisome position: 17.7

GC content: 71.24

Gene sequence:

>1224_bases
GTGTCCGGGGGACAATCGACCGCCAGGTCCACCACTTCGGTCGGGCTGCTGCTCGGCCTGACGCTGCTGGGCGGCTGCGT
GCGACTGGTCCCCGAATCGGGCGGGCCCCGCCCGGTGACGCCGCCCTCGCCTCCGCAGGCGGCAAAGCCGGCCACCGCCG
CGCTGACGGGCGTGACGCGTGGCCCGATTGCCGCAGGGCTGGGGTTCAAGCCAGACAACACAGCCGCCGCGCTGCGCTCG
TTCGTGCAGTCGTGCCCGCGCCTGACGAAGCGCACTGACAATTCAGGGCTGACCGTCCCCGCCGACTGGGCCCCGGCCTG
TGCCGCGGCACCGGGCTGGCCCGAAGGCGAGGCGGCGCGGTTCTTCTCGACCTATTTCGAAACCGCCGAGGTGGGCGACG
GCAATGCCTTCGTCACCGGGTACTTCGAACCGGAGATCGCGGGCGTGCGCACCCGCCAGCCCGGTTACGACATTCCCGTC
TATGCTATGCCGCCCGATCTGGTGCGGGCAAGGCCGGGCGATGCGCAACCGCTGCCCGACGGCAAGATGCCACTCGGTCG
CTATGACGACGCGGGCGTGTTCGTGCCCTACTACGACCGCGGCCAGATCGAGGACGGGGCACTGGCCGAAAAGGGACTGG
AGATTGCCTGGGCGGCAGACCCGGTCGAACTGTTCTTCCTCCAGATCCAGGGCTCGGGCCGCCTGCGCGCGCCCGACGGC
AGCGTGATCCGCATCGGTTTTGCCGCGCAGAACGGCCATCCCTATTCCGGCATCGGCTCGCTCATGCGCGAGCGCGGACT
GATCGGCAGCCAGCCGGGGCAATATCCCGGTTCGATGCAGGGCATCCAGCAGTACCTGCGCGACTATCCCGAAGCCGGCC
GCGCGCTGATGCGCCAGAACCGCAGCTATGTGTTCTTCCGCGAGCTGACCGGGCCCGGCCCCGTGGGCGCGCTCAACGTG
CCCATTTCGGGCCGCTCGACGGTGGCGGTCGACCCCGCCTTCGTGCCGCTGGGCGCGCCGGTCTGGCTCCAGCTTGACCG
GACGGAGGCGAGCGGGCTGTGGGTGGCGCAGGACACCGGAGGGGCGATCCAGGGCGCCAACCGCTTCGACAGCTTCTGGG
GCGCCGGCGCGGAGGCACGGCAGGTCGCGGGCGGCATGAGCGCGCGCGGCCGCGCGCTGCTCCTCCTGCCGAAGGGGACG
CTCGAGCGTCTGAACCAGCGCTGA

Upstream 100 bases:

>100_bases
ACGCTATCGACGCGCGCGACCTGTGGACCTTCCGCCGCGATCTGACCTCGCGCGATCCTGACTGGCTGCTCGACGAGACC
GACGAAGCCTGAGGGGCAAG

Downstream 100 bases:

>100_bases
TGCGCGCGCCGCGCGGCCTTTCGCCGGACGAGGCGGAGCTGTGGGAGAAGGTCGCCGCGACGATCAAGCCCATGCATCCC
GCCCGCCCCAAGGCGCGTGC

Product: MltA

Products: Muramic Acid Residue [C]

Alternate protein names: Mlt38; Murein hydrolase A [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSGGQSTARSTTSVGLLLGLTLLGGCVRLVPESGGPRPVTPPSPPQAAKPATAALTGVTRGPIAAGLGFKPDNTAAALRS
FVQSCPRLTKRTDNSGLTVPADWAPACAAAPGWPEGEAARFFSTYFETAEVGDGNAFVTGYFEPEIAGVRTRQPGYDIPV
YAMPPDLVRARPGDAQPLPDGKMPLGRYDDAGVFVPYYDRGQIEDGALAEKGLEIAWAADPVELFFLQIQGSGRLRAPDG
SVIRIGFAAQNGHPYSGIGSLMRERGLIGSQPGQYPGSMQGIQQYLRDYPEAGRALMRQNRSYVFFRELTGPGPVGALNV
PISGRSTVAVDPAFVPLGAPVWLQLDRTEASGLWVAQDTGGAIQGANRFDSFWGAGAEARQVAGGMSARGRALLLLPKGT
LERLNQR

Sequences:

>Translated_407_residues
MSGGQSTARSTTSVGLLLGLTLLGGCVRLVPESGGPRPVTPPSPPQAAKPATAALTGVTRGPIAAGLGFKPDNTAAALRS
FVQSCPRLTKRTDNSGLTVPADWAPACAAAPGWPEGEAARFFSTYFETAEVGDGNAFVTGYFEPEIAGVRTRQPGYDIPV
YAMPPDLVRARPGDAQPLPDGKMPLGRYDDAGVFVPYYDRGQIEDGALAEKGLEIAWAADPVELFFLQIQGSGRLRAPDG
SVIRIGFAAQNGHPYSGIGSLMRERGLIGSQPGQYPGSMQGIQQYLRDYPEAGRALMRQNRSYVFFRELTGPGPVGALNV
PISGRSTVAVDPAFVPLGAPVWLQLDRTEASGLWVAQDTGGAIQGANRFDSFWGAGAEARQVAGGMSARGRALLLLPKGT
LERLNQR
>Mature_406_residues
SGGQSTARSTTSVGLLLGLTLLGGCVRLVPESGGPRPVTPPSPPQAAKPATAALTGVTRGPIAAGLGFKPDNTAAALRSF
VQSCPRLTKRTDNSGLTVPADWAPACAAAPGWPEGEAARFFSTYFETAEVGDGNAFVTGYFEPEIAGVRTRQPGYDIPVY
AMPPDLVRARPGDAQPLPDGKMPLGRYDDAGVFVPYYDRGQIEDGALAEKGLEIAWAADPVELFFLQIQGSGRLRAPDGS
VIRIGFAAQNGHPYSGIGSLMRERGLIGSQPGQYPGSMQGIQQYLRDYPEAGRALMRQNRSYVFFRELTGPGPVGALNVP
ISGRSTVAVDPAFVPLGAPVWLQLDRTEASGLWVAQDTGGAIQGANRFDSFWGAGAEARQVAGGMSARGRALLLLPKGTL
ERLNQR

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=273, Percent_Identity=31.8681318681319, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 42882; Mature: 42751

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGQSTARSTTSVGLLLGLTLLGGCVRLVPESGGPRPVTPPSPPQAAKPATAALTGVTR
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
GPIAAGLGFKPDNTAAALRSFVQSCPRLTKRTDNSGLTVPADWAPACAAAPGWPEGEAAR
CCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHCCCCCCCCCHHHH
FFSTYFETAEVGDGNAFVTGYFEPEIAGVRTRQPGYDIPVYAMPPDLVRARPGDAQPLPD
HHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCCCEEEECCHHHHHCCCCCCCCCCC
GKMPLGRYDDAGVFVPYYDRGQIEDGALAEKGLEIAWAADPVELFFLQIQGSGRLRAPDG
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCEEEEECCCEEEEEEEEECCCEEECCCC
SVIRIGFAAQNGHPYSGIGSLMRERGLIGSQPGQYPGSMQGIQQYLRDYPEAGRALMRQN
CEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC
RSYVFFRELTGPGPVGALNVPISGRSTVAVDPAFVPLGAPVWLQLDRTEASGLWVAQDTG
CCEEEEEECCCCCCCCEEECCCCCCCEEEECCCEECCCCCEEEEEECCCCCCEEEEECCC
GAIQGANRFDSFWGAGAEARQVAGGMSARGRALLLLPKGTLERLNQR
CCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHCCC
>Mature Secondary Structure 
SGGQSTARSTTSVGLLLGLTLLGGCVRLVPESGGPRPVTPPSPPQAAKPATAALTGVTR
CCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
GPIAAGLGFKPDNTAAALRSFVQSCPRLTKRTDNSGLTVPADWAPACAAAPGWPEGEAAR
CCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHCCCCCCCCCHHHH
FFSTYFETAEVGDGNAFVTGYFEPEIAGVRTRQPGYDIPVYAMPPDLVRARPGDAQPLPD
HHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCCCEEEECCHHHHHCCCCCCCCCCC
GKMPLGRYDDAGVFVPYYDRGQIEDGALAEKGLEIAWAADPVELFFLQIQGSGRLRAPDG
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCEEEEECCCEEEEEEEEECCCEEECCCC
SVIRIGFAAQNGHPYSGIGSLMRERGLIGSQPGQYPGSMQGIQQYLRDYPEAGRALMRQN
CEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC
RSYVFFRELTGPGPVGALNVPISGRSTVAVDPAFVPLGAPVWLQLDRTEASGLWVAQDTG
CCEEEEEECCCCCCCCEEECCCCCCCEEEECCCEECCCCCEEEEEECCCCCCEEEEECCC
GAIQGANRFDSFWGAGAEARQVAGGMSARGRALLLLPKGTLERLNQR
CCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]