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The map label for this gene is pamO [H]

Identifier: 87198534

GI number: 87198534

Start: 550605

End: 552242

Strand: Reverse

Name: pamO [H]

Synonym: Saro_0510

Alternate gene names: 87198534

Gene position: 552242-550605 (Counterclockwise)

Preceding gene: 87198535

Following gene: 87198533

Centisome position: 15.51

GC content: 62.15

Gene sequence:

>1638_bases
ATGTCAGAATCAGGAACTCCCATCGTTGTTGATGCAGTCGTTGTCGGCGCAGGTGTCACGGGCATCTACCAGACCTATCT
CCTCGACCGGAACGGCATGTCGGTGCTTGGCGTCGATGCTGCGGACGACGTCGGGGGAACTTGGTACTGGAATCGCTATC
CGGGATGCCGCCTCGACACGGAAAGCTACGCCTACGGCTACTTCGCCCTCACCGGCATCATCCCCGACTGGAAGTGGAGC
GAGCGATTCGCGGGACAGGCGGAAATGCTCCGCTATGTGAATGCCGCCGCGGACGCGATGGACGTCCGCCGCCACTACAG
GTTCAAGACCAGGGTCCTGAGCGCGCACTTTCTCGATGACGAAAAGCGGTGGCAGATCACGCTGGACAGCGGCGAGATCG
TCCACGCCCGCTTCTTCATATCCGCCACCGGCCCGCTATCCGCTTCGAAGATGCCCGATTACAAGGGGATAGACCTCTTC
AAGGGCGAGGCGTTCCATTCCTCGCGCTGGCCCCGGGATGACCAGGGCAACCTTGCAGGCATGAATTTCGCCGGGAAGCG
GGTTGCCGTTCTCGGCACCGGCGCGACCGGGGTGCAGATCATTCCGATAGTAGCGGAAACCGCCGGAGAGCTGTTCGTCC
TGCAACGCAACCCGAACTGGTGCACCCCTCTAGGCAACACCCCGCTCAGCGACGAGGACATGAACCTCATCCGCACCCGA
TATCCGACGATCCTCGAGTATGTGAAGACGACGGATACCGCGTTCCCCTACCATCGCGATCCGCGCAAGGCGTCGCAGGT
GTCGGCCGAAGAGCGCGAGGAATTCTTCGAAAGGCTTTACGACCAGCCGGGCTACGGCATCTGGCTGAGTGGGTTTCGCG
ACCTGCTTCTCAGCCGGGAATCAAACCAGTTCCTTGCCGACTTCGTGGCCAGGAAGATCCGCCAGCGCGTCAAGGACCAG
GAGGTCGCAGAGAAGCTCATCCCCACCGACCATCCGTTCGGCTCCAAGCGTGTGCCCATGGAGACGAACTACTACGAGGC
GTACAACCGCGAGAACGTCCACCTCGTGGATCTCAAGGCCGCACCAATCGATGAGTTTGTCGAGAACGGCGTGATCATCG
GCGGTGAACTGCTGGAAGTCGACGTGATCATCTTCGCGACCGGCTTCGACGGCGTGACCGGCTCGCTCGACCGCATCGAC
ATCCGCGGGCGTGACGGACAGCGACTGATCGAGGCATGGGCCGATGGTCCGACGACCTACCTCGGTCTGCAGACGCGCAA
CTTCCCGAACTTCTTCGCGCTGGTCGGACCTCACAATGGCTCGGCTTTCTGCAACGTCGGCGTCTGCGGCGCGTTGCAGG
CGGAATGGGTCACCCAGATGCTGCTCTACATGGCAGCGCGCGGGTTCGTGGTTGCCGAGCCGACCGAAGAAGCCGAGGCC
GCCTGGACCGAGGCGATCTATCGCGATTTCGAACGAACGCTGATGGCTGAAACCAACGCCTGGTGGATCAAGGTCACCCA
CAAGCCGGACGGCAGCGTGGTGCGCCGAACGCTGGTCTACGTCGGCGGAGGCCCCGAGTACCGCCGACGCTGCGAGCAGG
TCGCCTATTGCGATTACGAAGGCTTCGAAATGGCCTGA

Upstream 100 bases:

>100_bases
CTGTTGCAACATAACCTAATTTTGATTAGGTGAATTTTATAGATTCAAGAACGGGCCGTGAGCCCTGAACGCAGCGCCGA
AACAAGGCTGAGGAATGGCA

Downstream 100 bases:

>100_bases
CCATCCGATGCTTCGGCTGGAACGTCTCCTTAATGAGTAAGCACGCGATGATTGATCTGAAAGTCGTCAAGCGCGACGGC
ACCAAACTTACCCTTCAGGC

Product: cyclohexanone monooxygenase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MSESGTPIVVDAVVVGAGVTGIYQTYLLDRNGMSVLGVDAADDVGGTWYWNRYPGCRLDTESYAYGYFALTGIIPDWKWS
ERFAGQAEMLRYVNAAADAMDVRRHYRFKTRVLSAHFLDDEKRWQITLDSGEIVHARFFISATGPLSASKMPDYKGIDLF
KGEAFHSSRWPRDDQGNLAGMNFAGKRVAVLGTGATGVQIIPIVAETAGELFVLQRNPNWCTPLGNTPLSDEDMNLIRTR
YPTILEYVKTTDTAFPYHRDPRKASQVSAEEREEFFERLYDQPGYGIWLSGFRDLLLSRESNQFLADFVARKIRQRVKDQ
EVAEKLIPTDHPFGSKRVPMETNYYEAYNRENVHLVDLKAAPIDEFVENGVIIGGELLEVDVIIFATGFDGVTGSLDRID
IRGRDGQRLIEAWADGPTTYLGLQTRNFPNFFALVGPHNGSAFCNVGVCGALQAEWVTQMLLYMAARGFVVAEPTEEAEA
AWTEAIYRDFERTLMAETNAWWIKVTHKPDGSVVRRTLVYVGGGPEYRRRCEQVAYCDYEGFEMA

Sequences:

>Translated_545_residues
MSESGTPIVVDAVVVGAGVTGIYQTYLLDRNGMSVLGVDAADDVGGTWYWNRYPGCRLDTESYAYGYFALTGIIPDWKWS
ERFAGQAEMLRYVNAAADAMDVRRHYRFKTRVLSAHFLDDEKRWQITLDSGEIVHARFFISATGPLSASKMPDYKGIDLF
KGEAFHSSRWPRDDQGNLAGMNFAGKRVAVLGTGATGVQIIPIVAETAGELFVLQRNPNWCTPLGNTPLSDEDMNLIRTR
YPTILEYVKTTDTAFPYHRDPRKASQVSAEEREEFFERLYDQPGYGIWLSGFRDLLLSRESNQFLADFVARKIRQRVKDQ
EVAEKLIPTDHPFGSKRVPMETNYYEAYNRENVHLVDLKAAPIDEFVENGVIIGGELLEVDVIIFATGFDGVTGSLDRID
IRGRDGQRLIEAWADGPTTYLGLQTRNFPNFFALVGPHNGSAFCNVGVCGALQAEWVTQMLLYMAARGFVVAEPTEEAEA
AWTEAIYRDFERTLMAETNAWWIKVTHKPDGSVVRRTLVYVGGGPEYRRRCEQVAYCDYEGFEMA
>Mature_544_residues
SESGTPIVVDAVVVGAGVTGIYQTYLLDRNGMSVLGVDAADDVGGTWYWNRYPGCRLDTESYAYGYFALTGIIPDWKWSE
RFAGQAEMLRYVNAAADAMDVRRHYRFKTRVLSAHFLDDEKRWQITLDSGEIVHARFFISATGPLSASKMPDYKGIDLFK
GEAFHSSRWPRDDQGNLAGMNFAGKRVAVLGTGATGVQIIPIVAETAGELFVLQRNPNWCTPLGNTPLSDEDMNLIRTRY
PTILEYVKTTDTAFPYHRDPRKASQVSAEEREEFFERLYDQPGYGIWLSGFRDLLLSRESNQFLADFVARKIRQRVKDQE
VAEKLIPTDHPFGSKRVPMETNYYEAYNRENVHLVDLKAAPIDEFVENGVIIGGELLEVDVIIFATGFDGVTGSLDRIDI
RGRDGQRLIEAWADGPTTYLGLQTRNFPNFFALVGPHNGSAFCNVGVCGALQAEWVTQMLLYMAARGFVVAEPTEEAEAA
WTEAIYRDFERTLMAETNAWWIKVTHKPDGSVVRRTLVYVGGGPEYRRRCEQVAYCDYEGFEMA

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=226, Percent_Identity=23.4513274336283, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4503755, Length=229, Percent_Identity=24.4541484716157, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19921694, Length=232, Percent_Identity=22.8448275862069, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 61378; Mature: 61247

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESGTPIVVDAVVVGAGVTGIYQTYLLDRNGMSVLGVDAADDVGGTWYWNRYPGCRLDT
CCCCCCEEEEEEEEECCCHHHHHHHHEECCCCCEEEEECCCCCCCCCEEECCCCCCEECC
ESYAYGYFALTGIIPDWKWSERFAGQAEMLRYVNAAADAMDVRRHYRFKTRVLSAHFLDD
CCCEEEEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHEECCC
EKRWQITLDSGEIVHARFFISATGPLSASKMPDYKGIDLFKGEAFHSSRWPRDDQGNLAG
CCEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEC
MNFAGKRVAVLGTGATGVQIIPIVAETAGELFVLQRNPNWCTPLGNTPLSDEDMNLIRTR
CCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
YPTILEYVKTTDTAFPYHRDPRKASQVSAEEREEFFERLYDQPGYGIWLSGFRDLLLSRE
HHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCC
SNQFLADFVARKIRQRVKDQEVAEKLIPTDHPFGSKRVPMETNYYEAYNRENVHLVDLKA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEEC
APIDEFVENGVIIGGELLEVDVIIFATGFDGVTGSLDRIDIRGRDGQRLIEAWADGPTTY
CCHHHHHHCCEEECCEEEEEEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEE
LGLQTRNFPNFFALVGPHNGSAFCNVGVCGALQAEWVTQMLLYMAARGFVVAEPTEEAEA
EEEEECCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHH
AWTEAIYRDFERTLMAETNAWWIKVTHKPDGSVVRRTLVYVGGGPEYRRRCEQVAYCDYE
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHEEEEEEEECCCHHHHHHHHHHEECCCC
GFEMA
CCCCC
>Mature Secondary Structure 
SESGTPIVVDAVVVGAGVTGIYQTYLLDRNGMSVLGVDAADDVGGTWYWNRYPGCRLDT
CCCCCEEEEEEEEECCCHHHHHHHHEECCCCCEEEEECCCCCCCCCEEECCCCCCEECC
ESYAYGYFALTGIIPDWKWSERFAGQAEMLRYVNAAADAMDVRRHYRFKTRVLSAHFLDD
CCCEEEEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHEECCC
EKRWQITLDSGEIVHARFFISATGPLSASKMPDYKGIDLFKGEAFHSSRWPRDDQGNLAG
CCEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEC
MNFAGKRVAVLGTGATGVQIIPIVAETAGELFVLQRNPNWCTPLGNTPLSDEDMNLIRTR
CCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
YPTILEYVKTTDTAFPYHRDPRKASQVSAEEREEFFERLYDQPGYGIWLSGFRDLLLSRE
HHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCC
SNQFLADFVARKIRQRVKDQEVAEKLIPTDHPFGSKRVPMETNYYEAYNRENVHLVDLKA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEEC
APIDEFVENGVIIGGELLEVDVIIFATGFDGVTGSLDRIDIRGRDGQRLIEAWADGPTTY
CCHHHHHHCCEEECCEEEEEEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEE
LGLQTRNFPNFFALVGPHNGSAFCNVGVCGALQAEWVTQMLLYMAARGFVVAEPTEEAEA
EEEEECCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHH
AWTEAIYRDFERTLMAETNAWWIKVTHKPDGSVVRRTLVYVGGGPEYRRRCEQVAYCDYE
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHEEEEEEEECCCHHHHHHHHHHEECCCC
GFEMA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA