Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 86751765

GI number: 86751765

Start: 5280608

End: 5281351

Strand: Direct

Name: ompR [H]

Synonym: RPB_4667

Alternate gene names: 86751765

Gene position: 5280608-5281351 (Clockwise)

Preceding gene: 86751764

Following gene: 86751766

Centisome position: 99.04

GC content: 67.61

Gene sequence:

>744_bases
ATGAGCCACAGCCCGCACATCATCGTCGTCGACGACGAAGCCCCTGCCCGCGAAATGGTCGGCGACTATCTGCGCATGCA
CGGCTTCGCCGTGACGCTGTGCGACGGCGGCAAGAGCCTGCGCGCCGAGATCGAAACCAAGGTCCCCGACCTCGTGGTGC
TCGATCTCAACATGCCGGAGGAGGATGGCCTGTCAATCATCCGTGACCTCAAGGCCAAGACCAATGTGCCGGTGATCATG
CTGACCGCGACCGCCAGCCCGATCGACCGCGTGGTCGGCCTCGAGCTCGGCGCCGACGATTATGTCGCCAAGCCGTGCGA
GCTGCGGGAGTTGATGGCCCGGATCCGCTCGGTGCTGCGCCGTTCGGCGCCGCGCCCCACCGCAGCCCCTGCTTCGGCCG
CGGCACCGACCAAAGCCGCCCCCGAGCAGCTCGTGCGGTTCGGCACCAAATGGCTCGACCTCGAGGCCCAGGCGCTGCGC
GACGACGACGGCAACGAACATCCGCTGACGGCGTCCGAATTCGGCCTCCTGAAGGTGTTCGCCGCCAATCCCAAGCGGGT
ACTGTCGCGCGAACGGCTGCTCGAACTCGCCAATGCCCGCGACGCGGAGGCGTTCGACCGCGCCGTCGACCTGCGGATCA
TGCGGATTCGGCGCAAGATCGAGCCGGATCCGACGAAGCCGGCCGTGATCCGGACAATTCGCGGCGGAGGCTATTTGTTC
TCGCCGGCCGCCGAGCGTCCCTGA

Upstream 100 bases:

>100_bases
AGAAGATCATCGACATGCACGGCGGCAATGTCGGCGCCCACAGCCCCGGCCCTGGCCAGGGCGCGACCTTCACCATCACC
CTGCCCGCATCGCCCGCATC

Downstream 100 bases:

>100_bases
GCGCGAACGCACCCCGACCTCTCTGGAATTGCAGGACTTTTTGTCGCAATGTTTCTTCGCCGCAATTGCGACGAAACATT
TCTCCCGGTCACGAAACCAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSHSPHIIVVDDEAPAREMVGDYLRMHGFAVTLCDGGKSLRAEIETKVPDLVVLDLNMPEEDGLSIIRDLKAKTNVPVIM
LTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLRRSAPRPTAAPASAAAPTKAAPEQLVRFGTKWLDLEAQALR
DDDGNEHPLTASEFGLLKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGGGYLF
SPAAERP

Sequences:

>Translated_247_residues
MSHSPHIIVVDDEAPAREMVGDYLRMHGFAVTLCDGGKSLRAEIETKVPDLVVLDLNMPEEDGLSIIRDLKAKTNVPVIM
LTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLRRSAPRPTAAPASAAAPTKAAPEQLVRFGTKWLDLEAQALR
DDDGNEHPLTASEFGLLKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGGGYLF
SPAAERP
>Mature_246_residues
SHSPHIIVVDDEAPAREMVGDYLRMHGFAVTLCDGGKSLRAEIETKVPDLVVLDLNMPEEDGLSIIRDLKAKTNVPVIML
TATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLRRSAPRPTAAPASAAAPTKAAPEQLVRFGTKWLDLEAQALRD
DDGNEHPLTASEFGLLKVFAANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGGGYLFS
PAAERP

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=243, Percent_Identity=40.3292181069959, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=36.2869198312236, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788394, Length=244, Percent_Identity=34.4262295081967, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790863, Length=243, Percent_Identity=32.5102880658436, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786599, Length=240, Percent_Identity=37.9166666666667, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI2367329, Length=238, Percent_Identity=34.0336134453782, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786911, Length=235, Percent_Identity=33.1914893617021, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=34.7457627118644, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=30.8333333333333, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786784, Length=236, Percent_Identity=32.2033898305085, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787375, Length=236, Percent_Identity=30.5084745762712, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=31.3304721030043, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790552, Length=243, Percent_Identity=30.0411522633745, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082012, Length=243, Percent_Identity=29.6296296296296, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=36.5217391304348, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790437, Length=137, Percent_Identity=31.3868613138686, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788905, Length=127, Percent_Identity=35.4330708661417, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27145; Mature: 27013

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSPHIIVVDDEAPAREMVGDYLRMHGFAVTLCDGGKSLRAEIETKVPDLVVLDLNMPE
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCCC
EDGLSIIRDLKAKTNVPVIMLTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLR
HHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCEECCCHHHCCCHHHHHHHHHHHHHHH
RSAPRPTAAPASAAAPTKAAPEQLVRFGTKWLDLEAQALRDDDGNEHPLTASEFGLLKVF
HCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHCCCHHHHHCCCCCCCCCCCHHHCCEEEEE
AANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGGGYLF
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
SPAAERP
CCCCCCC
>Mature Secondary Structure 
SHSPHIIVVDDEAPAREMVGDYLRMHGFAVTLCDGGKSLRAEIETKVPDLVVLDLNMPE
CCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCCC
EDGLSIIRDLKAKTNVPVIMLTATASPIDRVVGLELGADDYVAKPCELRELMARIRSVLR
HHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCEECCCHHHCCCHHHHHHHHHHHHHHH
RSAPRPTAAPASAAAPTKAAPEQLVRFGTKWLDLEAQALRDDDGNEHPLTASEFGLLKVF
HCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHCCCHHHHHCCCCCCCCCCCHHHCCEEEEE
AANPKRVLSRERLLELANARDAEAFDRAVDLRIMRIRRKIEPDPTKPAVIRTIRGGGYLF
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
SPAAERP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]