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The map label for this gene is kdpE [H]

Identifier: 86751747

GI number: 86751747

Start: 5258176

End: 5258868

Strand: Direct

Name: kdpE [H]

Synonym: RPB_4649

Alternate gene names: 86751747

Gene position: 5258176-5258868 (Clockwise)

Preceding gene: 86751746

Following gene: 86751748

Centisome position: 98.62

GC content: 67.53

Gene sequence:

>693_bases
ATGAGCGTGAAATCGCGCGTGCTGGTGGTCGACGACGAACCGGCGATCCTGCGCTTTCTCAAGCCGGCGCTGGAAGCCAA
CGGCTACGACGTCTCGCACGCCGCGACCGTCACCGAGGCGATCAAGCGGGTCGCCGCGGATGCGCCCGACATTGTGCTGC
TCGATCTCGGCCTCGCCGACGGCGACGGCAAGGACGTCATCCGGCAGGTCCGCGCCTGGTCGGATCTGCCGATCCTGGTC
CTGTCCGCGCGCGAGCGCGAAGCCGAGAAGATCGAGTCGCTCGACCTCGGCGCCGACGACTACGTCAACAAGCCGTTCAA
CTCCGGCGAACTGATGGCGCGGATGCGCGCAGCGTTACGCCACCGGATGCAGCGCAACGCCGAGCCCGCCGCGCTGTCGG
TCGGCGGCATCGAGATCGACGCAGTTCGCCACCGCGTCACCCGCGACGGCGACGAGATCAAGCTGACGCCGAAGGAATTC
GAACTGCTGGCCTTCCTGGTGCGGCACGCCGGCCGCGTCGTCACCCACCGGCAGATTCTCGCAGCGGTGTGGGGACCGGC
GCACACCTCGGACACGCAATATCTGCGGGTCTATATCGGCCAGTTGCGCCAGAAGATCGAAGCGCATGCCGACGAGCCGC
GGATCATCCTGACCGAGCCCGGCATCGGCTATCGGATCGGCGACGCAGGCTGA

Upstream 100 bases:

>100_bases
ATGGCGGCGCGGTGTCCGCGCTCAGCCCCGTCGCGAACGGGCACGGCACGCGCTTCGTGCTCACCTTCATGCGCGACAGG
ACACAGGAGACGCCGCAGCC

Downstream 100 bases:

>100_bases
GTCTCCGCGCAAGGCAGGGTTCCGCGCGTGAGGATTGCCGGCGCGCTGGTTGCTGTGTTTGATGCCGGACCGCCGCGCGC
GCGGCCTCGCCATCCTCGAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSVKSRVLVVDDEPAILRFLKPALEANGYDVSHAATVTEAIKRVAADAPDIVLLDLGLADGDGKDVIRQVRAWSDLPILV
LSAREREAEKIESLDLGADDYVNKPFNSGELMARMRAALRHRMQRNAEPAALSVGGIEIDAVRHRVTRDGDEIKLTPKEF
ELLAFLVRHAGRVVTHRQILAAVWGPAHTSDTQYLRVYIGQLRQKIEAHADEPRIILTEPGIGYRIGDAG

Sequences:

>Translated_230_residues
MSVKSRVLVVDDEPAILRFLKPALEANGYDVSHAATVTEAIKRVAADAPDIVLLDLGLADGDGKDVIRQVRAWSDLPILV
LSAREREAEKIESLDLGADDYVNKPFNSGELMARMRAALRHRMQRNAEPAALSVGGIEIDAVRHRVTRDGDEIKLTPKEF
ELLAFLVRHAGRVVTHRQILAAVWGPAHTSDTQYLRVYIGQLRQKIEAHADEPRIILTEPGIGYRIGDAG
>Mature_229_residues
SVKSRVLVVDDEPAILRFLKPALEANGYDVSHAATVTEAIKRVAADAPDIVLLDLGLADGDGKDVIRQVRAWSDLPILVL
SAREREAEKIESLDLGADDYVNKPFNSGELMARMRAALRHRMQRNAEPAALSVGGIEIDAVRHRVTRDGDEIKLTPKEFE
LLAFLVRHAGRVVTHRQILAAVWGPAHTSDTQYLRVYIGQLRQKIEAHADEPRIILTEPGIGYRIGDAG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=47.2972972972973, Blast_Score=209, Evalue=9e-56,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=33.7777777777778, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=37.3873873873874, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=36.036036036036, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=32.4200913242009, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=203, Percent_Identity=37.9310344827586, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=30.9090909090909, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=29.5652173913043, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=31.5555555555556, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.4444444444444, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=29.3859649122807, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=29.9107142857143, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=30.9734513274336, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=28.1385281385281, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=128, Percent_Identity=31.25, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25394; Mature: 25263

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKSRVLVVDDEPAILRFLKPALEANGYDVSHAATVTEAIKRVAADAPDIVLLDLGLAD
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
GDGKDVIRQVRAWSDLPILVLSAREREAEKIESLDLGADDYVNKPFNSGELMARMRAALR
CCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHH
HRMQRNAEPAALSVGGIEIDAVRHRVTRDGDEIKLTPKEFELLAFLVRHAGRVVTHRQIL
HHHHCCCCCCEEEECCEEHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCHHHHHHHHH
AAVWGPAHTSDTQYLRVYIGQLRQKIEAHADEPRIILTEPGIGYRIGDAG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCC
>Mature Secondary Structure 
SVKSRVLVVDDEPAILRFLKPALEANGYDVSHAATVTEAIKRVAADAPDIVLLDLGLAD
CCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
GDGKDVIRQVRAWSDLPILVLSAREREAEKIESLDLGADDYVNKPFNSGELMARMRAALR
CCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHH
HRMQRNAEPAALSVGGIEIDAVRHRVTRDGDEIKLTPKEFELLAFLVRHAGRVVTHRQIL
HHHHCCCCCCEEEECCEEHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCHHHHHHHHH
AAVWGPAHTSDTQYLRVYIGQLRQKIEAHADEPRIILTEPGIGYRIGDAG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]