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The map label for this gene is cofC [H]

Identifier: 86751523

GI number: 86751523

Start: 5009692

End: 5010291

Strand: Reverse

Name: cofC [H]

Synonym: RPB_4422

Alternate gene names: 86751523

Gene position: 5010291-5009692 (Counterclockwise)

Preceding gene: 86751524

Following gene: 86751522

Centisome position: 93.97

GC content: 71.0

Gene sequence:

>600_bases
ATGACCCACGTTCTGATCCCCTGCAAACCGCTCGCGTTCGGCAAGTCGCGCCTGGCGAGCGCGCTCGATCCGATCGGCCG
GCGCTGGCTGTGCGAGCGCATGCTGCGCCGGACGCTGGCGGCGGCCGTTGCGGCCGTCGGTGCCGAGCAGGTGAGGGTGG
TGAGCGCGGACGCGCATGTCCACCGCGTCGCCGCGTCGTGCGGCGTGAGCGCGATCGACGACGAGGCCGACGGTCTCAAT
GGCGCCCTGGCCGTCGCGCGGCGCCAGCTGCTCCGGGACGTCACGACGCTGGCGCGCCTGATGATCCTGCCGATCGATCT
GCCCTATGTCGAGCCGGAGATCCTGCGCCGCGCCGCCGCCGAAGCCGCGGCGGTGATGATCGGGCCGGACCGCAAGTTCG
ATGGTACCAACCTGCTTTGCGTCGACGCGTGCTACGTGGCTTCGTTTCCGTTCCGCTACGGCCCGGCCAGCTTCCAGCGG
CACGCCGACGCGGCGCGCGCGCTCGGAACGACGCCGGCCATCATGGTCGATCAGCGTATCGCCTTCGATCTCGACGCGCC
GGACGACTATCGGGAGTGGGCGAATCACGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCCCGGTCGATGCCGAGCGCCGCGACGCCAGCTTCGCCGCGCCGGAGCTGCAGGATCTGGTGATGACACCGTTCGTGCCG
AAGCAGATGGCGCTGGCACG

Downstream 100 bases:

>100_bases
AGCGGCGAAAGGCACCGTCCGTCCCATGCCCATGTCGGTCGCGAACGCGCGAGGCCGTTCGGCTTCGTCCGCGGCGCCCT
TGTTGCCGCATGCGGTGTCC

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTHVLIPCKPLAFGKSRLASALDPIGRRWLCERMLRRTLAAAVAAVGAEQVRVVSADAHVHRVAASCGVSAIDDEADGLN
GALAVARRQLLRDVTTLARLMILPIDLPYVEPEILRRAAAEAAAVMIGPDRKFDGTNLLCVDACYVASFPFRYGPASFQR
HADAARALGTTPAIMVDQRIAFDLDAPDDYREWANHAAA

Sequences:

>Translated_199_residues
MTHVLIPCKPLAFGKSRLASALDPIGRRWLCERMLRRTLAAAVAAVGAEQVRVVSADAHVHRVAASCGVSAIDDEADGLN
GALAVARRQLLRDVTTLARLMILPIDLPYVEPEILRRAAAEAAAVMIGPDRKFDGTNLLCVDACYVASFPFRYGPASFQR
HADAARALGTTPAIMVDQRIAFDLDAPDDYREWANHAAA
>Mature_198_residues
THVLIPCKPLAFGKSRLASALDPIGRRWLCERMLRRTLAAAVAAVGAEQVRVVSADAHVHRVAASCGVSAIDDEADGLNG
ALAVARRQLLRDVTTLARLMILPIDLPYVEPEILRRAAAEAAAVMIGPDRKFDGTNLLCVDACYVASFPFRYGPASFQRH
ADAARALGTTPAIMVDQRIAFDLDAPDDYREWANHAAA

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor [H]

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002835 [H]

Pfam domain/function: PF01983 DUF121 [H]

EC number: =2.7.7.68 [H]

Molecular weight: Translated: 21488; Mature: 21357

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVLIPCKPLAFGKSRLASALDPIGRRWLCERMLRRTLAAAVAAVGAEQVRVVSADAHV
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCHHH
HRVAASCGVSAIDDEADGLNGALAVARRQLLRDVTTLARLMILPIDLPYVEPEILRRAAA
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
EAAAVMIGPDRKFDGTNLLCVDACYVASFPFRYGPASFQRHADAARALGTTPAIMVDQRI
HHHEEEECCCCCCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHH
AFDLDAPDDYREWANHAAA
EEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
THVLIPCKPLAFGKSRLASALDPIGRRWLCERMLRRTLAAAVAAVGAEQVRVVSADAHV
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCHHH
HRVAASCGVSAIDDEADGLNGALAVARRQLLRDVTTLARLMILPIDLPYVEPEILRRAAA
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
EAAAVMIGPDRKFDGTNLLCVDACYVASFPFRYGPASFQRHADAARALGTTPAIMVDQRI
HHHEEEECCCCCCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHH
AFDLDAPDDYREWANHAAA
EEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA