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The map label for this gene is kdgR [H]

Identifier: 86751507

GI number: 86751507

Start: 4994082

End: 4994858

Strand: Reverse

Name: kdgR [H]

Synonym: RPB_4406

Alternate gene names: 86751507

Gene position: 4994858-4994082 (Counterclockwise)

Preceding gene: 86751508

Following gene: 86751506

Centisome position: 93.68

GC content: 63.32

Gene sequence:

>777_bases
ATGGTTAGTGTGGGAAAGACGGCGACCGGCAGTCAGACCGTCGCGCGTGCTTTGGCGGTGCTGGAGTTGCTGGGGCAGGA
AGGGGAGCTCGGCGTACGCGAACTGGGCCGCCAGCTCGGCGTGGCGCCGAGCATCGCGCAGCGCTTGATCAACACTTTGT
CCGAAGCCGGCTTCGTCGAGAAGTCGCTGGGAAATTCGAAGTGGAAGATCGGCTACAAGGCATTCCAGATCGGCTCGGCG
TTCCTCGCCTCGACCGACCTGAACGCCGCCACTGCACCTGAACTGCACCTACTTGCCGAGCAGCACCAGGTCAACAGCTT
CCTTGGCGTGCTGCGCGGCCAGGATGTCGTGTATCTGGCGACGGTGCAGAGTGGCGGCCCGATTTCGATTACTAACGCGC
CGGGATCACGCACCTATCTTCATTCGACCGCGCTCGGCAAAGCTCTGCTGCTCGACAGATCGGACGACGAAGTCCAGGCT
CTGCTCGGCACCGGCCCGCTCAAACAGCTGACGAAGAAGACAAAGCGCTCGGTGTCCGCAATCCTCAAAGATCTCAAGGA
GGGTCGTCGGCTGGGCTACGTCATCTGCGACGAGGAAAACCTCGAAAACGTCTTCGCCGTCGGAGTCCCCGTTCGCGACG
CCAGCGGCGGTATCATCGCCGCCCTGAGCGGCGCCGTGCCACGGCAGCGATTGTCGGCTCGCGCCATCGAAGAGCTCTGC
GAGCTGGTCAAGGCATCTGCGACCCGAGCGTCTCGGCGGCTCGGCTCGCTCAAGTGA

Upstream 100 bases:

>100_bases
GGCTTTGAAATGATGCCGGCAACCGAGTATCCGCATTGCCTGCCGATGCCGTGTCGTCGCGCGCTGAACGGCAGCAGTTT
CTCGCTGGGACGAAATCCAG

Downstream 100 bases:

>100_bases
ATATCCACTCCGCTGAACTATGGGGCAAGTCCACTCGCCGTCGCCGGGCACATCCCGGGCAGAACCAAGCGAGCTGCGAC
AGTCACTCGCGTGAACGCTT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MVSVGKTATGSQTVARALAVLELLGQEGELGVRELGRQLGVAPSIAQRLINTLSEAGFVEKSLGNSKWKIGYKAFQIGSA
FLASTDLNAATAPELHLLAEQHQVNSFLGVLRGQDVVYLATVQSGGPISITNAPGSRTYLHSTALGKALLLDRSDDEVQA
LLGTGPLKQLTKKTKRSVSAILKDLKEGRRLGYVICDEENLENVFAVGVPVRDASGGIIAALSGAVPRQRLSARAIEELC
ELVKASATRASRRLGSLK

Sequences:

>Translated_258_residues
MVSVGKTATGSQTVARALAVLELLGQEGELGVRELGRQLGVAPSIAQRLINTLSEAGFVEKSLGNSKWKIGYKAFQIGSA
FLASTDLNAATAPELHLLAEQHQVNSFLGVLRGQDVVYLATVQSGGPISITNAPGSRTYLHSTALGKALLLDRSDDEVQA
LLGTGPLKQLTKKTKRSVSAILKDLKEGRRLGYVICDEENLENVFAVGVPVRDASGGIIAALSGAVPRQRLSARAIEELC
ELVKASATRASRRLGSLK
>Mature_258_residues
MVSVGKTATGSQTVARALAVLELLGQEGELGVRELGRQLGVAPSIAQRLINTLSEAGFVEKSLGNSKWKIGYKAFQIGSA
FLASTDLNAATAPELHLLAEQHQVNSFLGVLRGQDVVYLATVQSGGPISITNAPGSRTYLHSTALGKALLLDRSDDEVQA
LLGTGPLKQLTKKTKRSVSAILKDLKEGRRLGYVICDEENLENVFAVGVPVRDASGGIIAALSGAVPRQRLSARAIEELC
ELVKASATRASRRLGSLK

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=253, Percent_Identity=28.8537549407115, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786715, Length=249, Percent_Identity=27.710843373494, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786468, Length=245, Percent_Identity=28.1632653061224, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082359, Length=255, Percent_Identity=28.6274509803922, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790752, Length=247, Percent_Identity=24.2914979757085, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27255; Mature: 27255

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS51000 HTH_DEOR_2 ; PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVGKTATGSQTVARALAVLELLGQEGELGVRELGRQLGVAPSIAQRLINTLSEAGFVE
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
KSLGNSKWKIGYKAFQIGSAFLASTDLNAATAPELHLLAEQHQVNSFLGVLRGQDVVYLA
HHCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
TVQSGGPISITNAPGSRTYLHSTALGKALLLDRSDDEVQALLGTGPLKQLTKKTKRSVSA
EECCCCCEEEECCCCCCCEEHHHHHHHHHEECCCCHHHHHHHCCCHHHHHHHHHHHHHHH
ILKDLKEGRRLGYVICDEENLENVFAVGVPVRDASGGIIAALSGAVPRQRLSARAIEELC
HHHHHHCCCCEEEEEECCCCCCCEEEECCCEECCCCCEEEECCCCCCHHHHHHHHHHHHH
ELVKASATRASRRLGSLK
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVSVGKTATGSQTVARALAVLELLGQEGELGVRELGRQLGVAPSIAQRLINTLSEAGFVE
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
KSLGNSKWKIGYKAFQIGSAFLASTDLNAATAPELHLLAEQHQVNSFLGVLRGQDVVYLA
HHCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
TVQSGGPISITNAPGSRTYLHSTALGKALLLDRSDDEVQALLGTGPLKQLTKKTKRSVSA
EECCCCCEEEECCCCCCCEEHHHHHHHHHEECCCCHHHHHHHCCCHHHHHHHHHHHHHHH
ILKDLKEGRRLGYVICDEENLENVFAVGVPVRDASGGIIAALSGAVPRQRLSARAIEELC
HHHHHHCCCCEEEEEECCCCCCCEEEECCCEECCCCCEEEECCCCCCHHHHHHHHHHHHH
ELVKASATRASRRLGSLK
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]