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The map label for this gene is crp [C]

Identifier: 86751337

GI number: 86751337

Start: 4807808

End: 4808470

Strand: Reverse

Name: crp [C]

Synonym: RPB_4231

Alternate gene names: 86751337

Gene position: 4808470-4807808 (Counterclockwise)

Preceding gene: 86751338

Following gene: 86751336

Centisome position: 90.19

GC content: 61.39

Gene sequence:

>663_bases
ATGAAGCTGGAAGCCGACTTCGACTATCGAGAGTACTTCTCCAGGCCGGGCGCTGGGAAGGCGCTGCTGCGGTTTGCGCG
GGATCAGGTGATCTTCTCCCAAGGCGATGCCGCCGACAACGTCTTCTTTCTGCTCGAGGGTCGGATCAAAGTCGTCGTGT
TGTCCGCGCAGGGCAAGGAGGCTGCGACCCGGCTGGTGGAGTCCGGGCAGTTCTTCGGCGACGGCTGCCTGATCGGCGAT
GAAACCCGATACGCGACCACGATCGCGATGCGCGATTGCGTCGTCGCCTCGATCAACAAATGCCGGGTGATCGAGGCCTT
GCGCACCGAGCCGGATTTCGCCGAACTGTTCATTCGCCATCTGCTGATCCGCAACCGCGGGATGGAAGAGGATCTGATCG
ATCAGCTGTTCAATTCGAGCGAGAAGCGGCTGGCGCGGTTGCTACTGCGTCTGTCGAAGCTCGACGATGACGGCAGCGCG
CAACCGATCGCGCCGCATATCAGCCAGGAGACGCTGGCCGAAATGATCGGCACCACCCGCTCGCGCGTCAGCTTCTTCAT
GAACAAGTTCCGCAAGCTCGGTCTGATCAGCTACGATCGCAACATCGAGGTGCATCCGCGGCTGAGCGCGATGTTGCAGG
ATCGCTCTCAGGCCCGCAACTGA

Upstream 100 bases:

>100_bases
CCTCGTACCTTCACTAGGAATGGAGTTTTTACCAGCGTTTTCAGGCTACGGCAGTCTATCATTTGAGCCGCATCAGCTTC
GCAGGGAGTTGGAGAGGCCA

Downstream 100 bases:

>100_bases
GACCGGGCGGAGGCACAGGCCTGATACCGGGCTCGCCCCCAACGCCAGGCAGAGCACGGCTGCATCCCGCCCCCTCGCGC
TTTGTGCGGCCGTTTGTATA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Transcriptional Regulator Crp/Fnr Family; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulator; Response Regulator Receiver; Crp/Fnr Family Transcriptional Regulator; CAMP-Regulatory Protein; Cyclic-AMP Receptor-Like Protein

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKLEADFDYREYFSRPGAGKALLRFARDQVIFSQGDAADNVFFLLEGRIKVVVLSAQGKEAATRLVESGQFFGDGCLIGD
ETRYATTIAMRDCVVASINKCRVIEALRTEPDFAELFIRHLLIRNRGMEEDLIDQLFNSSEKRLARLLLRLSKLDDDGSA
QPIAPHISQETLAEMIGTTRSRVSFFMNKFRKLGLISYDRNIEVHPRLSAMLQDRSQARN

Sequences:

>Translated_220_residues
MKLEADFDYREYFSRPGAGKALLRFARDQVIFSQGDAADNVFFLLEGRIKVVVLSAQGKEAATRLVESGQFFGDGCLIGD
ETRYATTIAMRDCVVASINKCRVIEALRTEPDFAELFIRHLLIRNRGMEEDLIDQLFNSSEKRLARLLLRLSKLDDDGSA
QPIAPHISQETLAEMIGTTRSRVSFFMNKFRKLGLISYDRNIEVHPRLSAMLQDRSQARN
>Mature_220_residues
MKLEADFDYREYFSRPGAGKALLRFARDQVIFSQGDAADNVFFLLEGRIKVVVLSAQGKEAATRLVESGQFFGDGCLIGD
ETRYATTIAMRDCVVASINKCRVIEALRTEPDFAELFIRHLLIRNRGMEEDLIDQLFNSSEKRLARLLLRLSKLDDDGSA
QPIAPHISQETLAEMIGTTRSRVSFFMNKFRKLGLISYDRNIEVHPRLSAMLQDRSQARN

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24983; Mature: 24983

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEADFDYREYFSRPGAGKALLRFARDQVIFSQGDAADNVFFLLEGRIKVVVLSAQGKE
CCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECCCHH
AATRLVESGQFFGDGCLIGDETRYATTIAMRDCVVASINKCRVIEALRTEPDFAELFIRH
HHHHHHHCCCEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLIRNRGMEEDLIDQLFNSSEKRLARLLLRLSKLDDDGSAQPIAPHISQETLAEMIGTTR
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHH
SRVSFFMNKFRKLGLISYDRNIEVHPRLSAMLQDRSQARN
HHHHHHHHHHHHCCCEEECCCCEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLEADFDYREYFSRPGAGKALLRFARDQVIFSQGDAADNVFFLLEGRIKVVVLSAQGKE
CCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECCCHH
AATRLVESGQFFGDGCLIGDETRYATTIAMRDCVVASINKCRVIEALRTEPDFAELFIRH
HHHHHHHCCCEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLIRNRGMEEDLIDQLFNSSEKRLARLLLRLSKLDDDGSAQPIAPHISQETLAEMIGTTR
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHH
SRVSFFMNKFRKLGLISYDRNIEVHPRLSAMLQDRSQARN
HHHHHHHHHHHHCCCEEECCCCEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA